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Search of human proteins with 21536294
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536294 claudin 14 [Homo sapiens]
(239 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225703142 claudin 14 [Homo sapiens] 487 e-138
gi|21536294 claudin 14 [Homo sapiens] 487 e-138
gi|225703138 claudin 14 [Homo sapiens] 487 e-138
gi|6912314 claudin 14 [Homo sapiens] 487 e-138
gi|225703140 claudin 14 [Homo sapiens] 487 e-138
gi|9966781 claudin 2 [Homo sapiens] 222 3e-58
gi|4502877 claudin 4 [Homo sapiens] 196 1e-50
gi|4502875 claudin 3 [Homo sapiens] 194 6e-50
gi|10863887 claudin 1 [Homo sapiens] 192 2e-49
gi|11141861 claudin 9 [Homo sapiens] 187 7e-48
gi|183979973 claudin 19 isoform a [Homo sapiens] 186 1e-47
gi|153792186 claudin 7 [Homo sapiens] 184 4e-47
gi|183979975 claudin 19 isoform b [Homo sapiens] 184 8e-47
gi|153792768 claudin 6 [Homo sapiens] 177 7e-45
gi|47716519 claudin 20 [Homo sapiens] 172 2e-43
gi|6912316 claudin 17 [Homo sapiens] 166 1e-41
gi|195947374 claudin 5 [Homo sapiens] 166 2e-41
gi|195947372 claudin 5 [Homo sapiens] 166 2e-41
gi|40788011 claudin 8 [Homo sapiens] 162 2e-40
gi|7656981 claudin 15 [Homo sapiens] 133 1e-31
gi|5921465 claudin 10 isoform b [Homo sapiens] 127 7e-30
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 125 4e-29
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 122 4e-28
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 116 2e-26
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 116 2e-26
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 114 1e-25
gi|33598916 claudin 10 isoform a [Homo sapiens] 108 4e-24
gi|162417973 claudin 22 [Homo sapiens] 107 1e-23
gi|157820127 claudin-like [Homo sapiens] 98 7e-21
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 94 1e-19
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 487 bits (1254), Expect = e-138
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 487 bits (1254), Expect = e-138
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 487 bits (1254), Expect = e-138
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 487 bits (1254), Expect = e-138
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 487 bits (1254), Expect = e-138
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 222 bits (565), Expect = 3e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
LC +C +PY A A + A
Sbjct: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 194 bits (493), Expect = 6e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
LLC SC PR TT+ P +P P++ KD
Sbjct: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 187 bits (475), Expect = 7e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 181 LCLSC---QDEAPYRP---YQAPPRA 200
LC +C Q E P P Y P R+
Sbjct: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
LC +C + P RP +P R + A P + PA+ K
Sbjct: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 184 bits (468), Expect = 4e-47
Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA++ +QLLGF ++ LG VG + T +P W+ +++ G NI+TA + KGLWM+CV STG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
+ C++Y S+LAL LQA RALMV+S +L +A A +GMKCTRC K A+
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
GG +FI+AGL +VA SW + +V +FYNPL+P+ +K+E G A+++G+ S+L ++GG
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203
LL SC + +A YR ++ P++ ++
Sbjct: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 184 bits (466), Expect = 8e-47
Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCLSCQDEAPYRPYQAP 197
LC +C + P RP +P
Sbjct: 181 FLCCTCPE--PERPNSSP 196
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 177 bits (449), Expect = 7e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
LC +C P Q P + +APA
Sbjct: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 172 bits (437), Expect = 2e-43
Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MAS +QLL F+L+ G+ G L T+LP+W+ V +NI+TA+ L GLWM+C W+STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
++ C + S+L+LP +QAARA MV++C+LS + + +GMKCTR K+ +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GG F+ AG+ +++ W T +++ NF + +P K E G A+Y+GFIS+ L I G +
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208
C SC EA P P + T N +
Sbjct: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 166 bits (421), Expect = 1e-41
Identities = 96/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA +Q+ G +L FLGMVGTL TT+LP WR +A VG+NI+ +GLWM C+ +
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC+ Y SLLALP L+ ARALM ++ LS IA + GMK +C G+ + +L
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCT-GSNERAKAYLL 119
Query: 121 G--GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
G G LFIL G+ ++ VSWT N ++++FYNP + G K E+G AL+LG+ S+++ IGG
Sbjct: 120 GTSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGG 179
Query: 179 TLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGY 233
LLC C + Y+ P P Y+ P K R ++ S T + Y
Sbjct: 180 GLLCGFCCCNRKKQGYRYP----------VPGYRVPHTDK-RRNTTMLSKTSTSY 223
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
LC D + Y AP R T T
Sbjct: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
LC D + Y AP R T T
Sbjct: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 162 bits (411), Expect = 2e-40
Identities = 79/205 (38%), Positives = 125/205 (60%), Gaps = 3/205 (1%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA+ A+++ G L +GMVGT+ T++P WR +A + NI+ ++ +GLWM CV +
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
QC+IY SLLAL DLQAAR LM + ++S +A A++GMKCTRC K +
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
G +FI+ G++ ++ VSW N ++++FYN ++ K E+G+ALYLG+ ++ + ++GG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 180 LLC--LSCQDEAPYRPYQAPPRATT 202
L C C +++ Y P TT
Sbjct: 181 LFCCVFCCNEKSSSYRYSIPSHRTT 205
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
Query: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
Query: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
Query: 182 CLSC---QDEAP----YRPYQAP 197
C +C DE P RPYQAP
Sbjct: 180 CSACCCGSDEDPAASARRPYQAP 202
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 127 bits (320), Expect = 7e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
Query: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
Query: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
Query: 179 TLLCLSCQD 187
+ C S D
Sbjct: 177 VIFCFSISD 185
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 125 bits (313), Expect = 4e-29
Identities = 71/202 (35%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
MA TA Q LGF++S +G+ G + T + W T + N +TAV +GLW CV S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
+C+ Y +LL LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 ISSSLSLIGGTLLCLSCQDEAP 190
++ L+LIGG ++C++C+ AP
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAP 201
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
Query: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 ISSSLSLIGGTLLCLSCQDEAP 190
++ L+LIGG ++C++C+ AP
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAP 201
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 116 bits (290), Expect = 2e-26
Identities = 68/190 (35%), Positives = 106/190 (55%), Gaps = 6/190 (3%)
Query: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63
TA+Q +G LLSFLG + ++ITT LPHW+ ++ ++ ++ GLW CV Q
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
Query: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122
C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181
L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 -CLSCQDEAP 190
C +C AP
Sbjct: 184 NCAACSSHAP 193
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 116 bits (290), Expect = 2e-26
Identities = 68/190 (35%), Positives = 106/190 (55%), Gaps = 6/190 (3%)
Query: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63
TA+Q +G LLSFLG + ++ITT LPHW+ ++ ++ ++ GLW CV Q
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
Query: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122
C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181
L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 -CLSCQDEAP 190
C +C AP
Sbjct: 184 NCAACSSHAP 193
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 114 bits (284), Expect = 1e-25
Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)
Query: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63
TA+Q +G LLS LG + ++ITT LPHW+ ++ ++ ++ GLW CV Q
Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
Query: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122
C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181
L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 -CLSCQDEAP 190
C +C AP
Sbjct: 184 NCAACSSHAP 193
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 108 bits (270), Expect = 4e-24
Identities = 59/177 (33%), Positives = 94/177 (53%), Gaps = 3/177 (1%)
Query: 12 LLSFLGMVGTLIT-TILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSL 70
L+S +G G L+ T W+ T ++++TA +GLWM C ++ G + C+ + ++
Sbjct: 9 LVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGNALGSFHCRPHFTI 67
Query: 71 LALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGL 130
+ +QA R LM+ + L A+ GMKCT+ AK A L G +FIL+GL
Sbjct: 68 FKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGL 127
Query: 131 LCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQD 187
M S N + F++PL K+E+G AL++G+ +SL +IGG + C S D
Sbjct: 128 CSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSISD 183
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 107 bits (266), Expect = 1e-23
Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)
Query: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63
T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q
Sbjct: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
Query: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122
C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181
L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL
Sbjct: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 -CLSCQDEAP 190
C +C AP
Sbjct: 184 HCAACSSHAP 193
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 97.8 bits (242), Expect = 7e-21
Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)
Query: 6 VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65
VQL G LLS LG V + +TTILP W+ T ++ N + +++ G+W CV C+
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
Query: 66 IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124
+ S L+LPQ+LQ AR LMV S L + G +C + + K +LG TL
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183
A ++ VSW + +Q+F++ +P + ++E G ALYLG+ + +GG LL
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217
S +++ P+ P A P T + AP + ++
Sbjct: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 93.6 bits (231), Expect = 1e-19
Identities = 57/177 (32%), Positives = 85/177 (48%), Gaps = 22/177 (12%)
Query: 12 LLSFLGMVGTLIT-TILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSL 70
L+S +G G L+ T W+ T ++++TA +GLWM C +
Sbjct: 9 LVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGY------------- 54
Query: 71 LALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGL 130
+QA R LM+ + L A+ GMKCT+ AK A L G +FIL+GL
Sbjct: 55 ------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGL 108
Query: 131 LCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQD 187
M S N + F++PL K+E+G AL++G+ +SL +IGG + C S D
Sbjct: 109 CSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSISD 164
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.135 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,327,623
Number of Sequences: 37866
Number of extensions: 419595
Number of successful extensions: 2148
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2062
Number of HSP's gapped (non-prelim): 62
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.