BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens] (662 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens] 1314 0.0 gi|115387108 regulator of G-protein signalling 1 [Homo sapiens] 47 7e-05 gi|21361304 regulator of G-protein signalling 14 [Homo sapiens] 47 7e-05 gi|17864088 sorting nexin 13 [Homo sapiens] 46 1e-04 gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo ... 44 4e-04 gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 44 4e-04 gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo ... 44 4e-04 gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 44 4e-04 gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 44 4e-04 gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] 44 5e-04 gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo ... 44 6e-04 gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sa... 44 6e-04 gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo ... 44 6e-04 gi|85540441 regulator of G-protein signaling 21 [Homo sapiens] 43 8e-04 gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens] 42 0.002 gi|4506511 regulator of G-protein signalling 13 [Homo sapiens] 41 0.004 gi|21464139 regulator of G-protein signalling 13 [Homo sapiens] 41 0.004 gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ... 39 0.012 gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo... 39 0.012 gi|38327599 regulator of G-protein signalling 12 isoform 3 [Homo... 39 0.012 gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ... 39 0.015 gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ... 39 0.015 gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 38 0.026 gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 38 0.026 gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 38 0.034 gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo ... 37 0.045 gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo... 37 0.045 gi|51873049 hypothetical protein LOC8603 [Homo sapiens] 35 0.22 gi|86990435 G protein signalling regulator 19 [Homo sapiens] 35 0.29 gi|5031705 G protein signalling regulator 19 [Homo sapiens] 35 0.29 >gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens] Length = 662 Score = 1314 bits (3401), Expect = 0.0 Identities = 662/662 (100%), Positives = 662/662 (100%) Query: 1 MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNH 60 MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNH Sbjct: 1 MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNH 60 Query: 61 ALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKS 120 ALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKS Sbjct: 61 ALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKS 120 Query: 121 SLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQS 180 SLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQS Sbjct: 121 SLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQS 180 Query: 181 SLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQ 240 SLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQ Sbjct: 181 SLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQ 240 Query: 241 ECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVN 300 ECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVN Sbjct: 241 ECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVN 300 Query: 301 TFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFL 360 TFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFL Sbjct: 301 TFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFL 360 Query: 361 RSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLA 420 RSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLA Sbjct: 361 RSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLA 420 Query: 421 AKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPL 480 AKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPL Sbjct: 421 AKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPL 480 Query: 481 RQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLTAPGSVGPPDESHPGS 540 RQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLTAPGSVGPPDESHPGS Sbjct: 481 RQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLTAPGSVGPPDESHPGS 540 Query: 541 SDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRE 600 SDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRE Sbjct: 541 SDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRE 600 Query: 601 SEPEPDVRKSKGSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKST 660 SEPEPDVRKSKGSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKST Sbjct: 601 SEPEPDVRKSKGSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKST 660 Query: 661 KL 662 KL Sbjct: 661 KL 662 >gi|115387108 regulator of G-protein signalling 1 [Homo sapiens] Length = 209 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 11/116 (9%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F +++ E + ++FWLA +++ KK + D + + +Y + A + Sbjct: 99 FGSFLKSEFSEENIEFWLACEDY------KKTESDLLPCKAEE--IYKAFVHSDAAKQIN 150 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDL 508 D R ES + P P CF + +T MEK P FL S++Y LNDL Sbjct: 151 IDFRTR---ESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDL 203 Score = 33.9 bits (76), Expect = 0.49 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 298 AVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFS 357 A + ++ DAAK I I R +I P CF AQ ++++ ME++ + Sbjct: 133 AEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPT----PTCFDEAQKVIYTLMEKDSYP 188 Query: 358 EFLRS 362 FL+S Sbjct: 189 RFLKS 193 >gi|21361304 regulator of G-protein signalling 14 [Homo sapiens] Length = 566 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 9/116 (7%) Query: 390 LFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATH 449 L YF+E+++KE + + FW A + FQ Q+ A Q QEA+N +Y ++ S QA Sbjct: 78 LAYFTEFLKKEFSAENVTFWKACERFQ-QIPASDTQQLAQEARN----IYQEFLSSQALS 132 Query: 450 PLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYL 505 P+ D L E + E P P+ F Q + M+ F+ S LY + L Sbjct: 133 PVNIDRQAWLGEE--VLAE--PRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECL 184 >gi|17864088 sorting nexin 13 [Homo sapiens] Length = 957 Score = 45.8 bits (107), Expect = 1e-04 Identities = 63/248 (25%), Positives = 103/248 (41%), Gaps = 37/248 (14%) Query: 377 TVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNF----QSQL-AAKKGQYDGQEA 431 TV L IL AL +F +YM++ L FW+ + + Q QL Q DG+ Sbjct: 371 TVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQ 430 Query: 432 QND--------AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQA 483 N A+ +Y++Y S +A+ + DD + ++ + E P P F R+ Sbjct: 431 TNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHE-DPTPEIFDDIQRKV 489 Query: 484 WTTM--EKVFLPGFLSSNLYYKYLNDL----IHSVRGDEFLGG---NVSLTAPGSVGPPD 534 + M ++ F P F + LY + L +L S RG + G N S T ++ D Sbjct: 490 YELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDD 549 Query: 535 ESHPGSSDSSASQSSVKKASI-----KILKNFDEAIIVDAASLDPESLYQRTYAGKMTFG 589 S+ S DS + + + K + AI V +L+ E +++ T+ Sbjct: 550 LSNVSSDDSVQLHAYISDTGVCNDHGKTYALY--AITVHRRNLNSEEMWK-------TYR 600 Query: 590 RVSDLGQF 597 R SD F Sbjct: 601 RYSDFHDF 608 >gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo sapiens] Length = 168 Score = 44.3 bits (103), Expect = 4e-04 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNF-----QSQLAAKKGQYDGQEAQND 434 L +L + L F ++ E + L+FWLA ++F QS++A+K Sbjct: 44 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASK------------ 91 Query: 435 AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPG 494 A ++ +Y ++QA + D R + N+ CF ++ + MEK P Sbjct: 92 AKKIFAEYIAIQACKEVNLDSYTREHTKDNL---QSVTRGCFDLAQKRIFGLMEKDSYPR 148 Query: 495 FLSSNLYYKYLN 506 FL S+LY +N Sbjct: 149 FLRSDLYLDLIN 160 Score = 32.7 bits (73), Expect = 1.1 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + A F +YI+ A K + + R + V CF LAQ +F Sbjct: 83 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNL----QSVTRGCFDLAQKRIF 138 Query: 349 SAMEQEHFSEFLRS 362 ME++ + FLRS Sbjct: 139 GLMEKDSYPRFLRS 152 >gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo sapiens] Length = 1198 Score = 44.3 bits (103), Expect = 4e-04 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNF-----QSQLAAKKGQYDGQEAQND 434 L +L + L F ++ E + L+FWLA ++F QS++A+K Sbjct: 1074 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASK------------ 1121 Query: 435 AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPG 494 A ++ +Y ++QA + D R + N+ CF ++ + MEK P Sbjct: 1122 AKKIFAEYIAIQACKEVNLDSYTREHTKDNL---QSVTRGCFDLAQKRIFGLMEKDSYPR 1178 Query: 495 FLSSNLYYKYLN 506 FL S+LY +N Sbjct: 1179 FLRSDLYLDLIN 1190 Score = 32.7 bits (73), Expect = 1.1 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + A F +YI+ A K + + R + V CF LAQ +F Sbjct: 1113 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNL----QSVTRGCFDLAQKRIF 1168 Query: 349 SAMEQEHFSEFLRS 362 ME++ + FLRS Sbjct: 1169 GLMEKDSYPRFLRS 1182 >gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo sapiens] Length = 311 Score = 44.3 bits (103), Expect = 4e-04 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNF-----QSQLAAKKGQYDGQEAQND 434 L +L + L F ++ E + L+FWLA ++F QS++A+K Sbjct: 187 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASK------------ 234 Query: 435 AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPG 494 A ++ +Y ++QA + D R + N+ CF ++ + MEK P Sbjct: 235 AKKIFAEYIAIQACKEVNLDSYTREHTKDNL---QSVTRGCFDLAQKRIFGLMEKDSYPR 291 Query: 495 FLSSNLYYKYLN 506 FL S+LY +N Sbjct: 292 FLRSDLYLDLIN 303 Score = 32.7 bits (73), Expect = 1.1 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + A F +YI+ A K + + R + V CF LAQ +F Sbjct: 226 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNL----QSVTRGCFDLAQKRIF 281 Query: 349 SAMEQEHFSEFLRS 362 ME++ + FLRS Sbjct: 282 GLMEKDSYPRFLRS 295 >gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo sapiens] Length = 519 Score = 44.3 bits (103), Expect = 4e-04 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNF-----QSQLAAKKGQYDGQEAQND 434 L +L + L F ++ E + L+FWLA ++F QS++A+K Sbjct: 395 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASK------------ 442 Query: 435 AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPG 494 A ++ +Y ++QA + D R + N+ CF ++ + MEK P Sbjct: 443 AKKIFAEYIAIQACKEVNLDSYTREHTKDNL---QSVTRGCFDLAQKRIFGLMEKDSYPR 499 Query: 495 FLSSNLYYKYLN 506 FL S+LY +N Sbjct: 500 FLRSDLYLDLIN 511 Score = 32.7 bits (73), Expect = 1.1 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + A F +YI+ A K + + R + V CF LAQ +F Sbjct: 434 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNL----QSVTRGCFDLAQKRIF 489 Query: 349 SAMEQEHFSEFLRS 362 ME++ + FLRS Sbjct: 490 GLMEKDSYPRFLRS 503 >gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo sapiens] Length = 917 Score = 44.3 bits (103), Expect = 4e-04 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNF-----QSQLAAKKGQYDGQEAQND 434 L +L + L F ++ E + L+FWLA ++F QS++A+K Sbjct: 793 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASK------------ 840 Query: 435 AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPG 494 A ++ +Y ++QA + D R + N+ CF ++ + MEK P Sbjct: 841 AKKIFAEYIAIQACKEVNLDSYTREHTKDNL---QSVTRGCFDLAQKRIFGLMEKDSYPR 897 Query: 495 FLSSNLYYKYLN 506 FL S+LY +N Sbjct: 898 FLRSDLYLDLIN 909 Score = 32.7 bits (73), Expect = 1.1 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + A F +YI+ A K + + R + V CF LAQ +F Sbjct: 832 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNL----QSVTRGCFDLAQKRIF 887 Query: 349 SAMEQEHFSEFLRS 362 ME++ + FLRS Sbjct: 888 GLMEKDSYPRFLRS 901 >gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] Length = 210 Score = 43.9 bits (102), Expect = 5e-04 Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 10/113 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F E++ E + L FWLA ++ K + + + + A ++Y+ Y S+ + + Sbjct: 98 FREFLRTEYSEENLLFWLACEDL-------KKEQNKKVIEEKARMIYEDYISILSPKEVS 150 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYL 505 D VR I N+ P P+ + Q +T M + P FL+S +Y ++ Sbjct: 151 LDSRVREVINRNLL---DPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFV 200 >gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo sapiens] Length = 187 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 10/127 (7%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILY 439 L +++ E L F +++ E + + FW++ + ++ + K A +Y Sbjct: 45 LENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSK-------LSPKAKKIY 97 Query: 440 DKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSN 499 +++ S+QAT + D R E N+ P CF ++ + MEK FL S Sbjct: 98 NEFISVQATKEVNLDSCTREETSRNMLE---PTITCFDEAQKKIFNLMEKDSYRRFLKSR 154 Query: 500 LYYKYLN 506 Y +N Sbjct: 155 FYLDLVN 161 >gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sapiens] Length = 205 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 10/127 (7%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILY 439 L +++ E L F +++ E + + FW++ + ++ + K A +Y Sbjct: 63 LENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSK-------LSPKAKKIY 115 Query: 440 DKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSN 499 +++ S+QAT + D R E N+ P CF ++ + MEK FL S Sbjct: 116 NEFISVQATKEVNLDSCTREETSRNMLE---PTITCFDEAQKKIFNLMEKDSYRRFLKSR 172 Query: 500 LYYKYLN 506 Y +N Sbjct: 173 FYLDLVN 179 >gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo sapiens] Length = 302 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 10/127 (7%) Query: 380 LADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILY 439 L +++ E L F +++ E + + FW++ + ++ + K A +Y Sbjct: 160 LENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSK-------LSPKAKKIY 212 Query: 440 DKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSN 499 +++ S+QAT + D R E N+ P CF ++ + MEK FL S Sbjct: 213 NEFISVQATKEVNLDSCTREETSRNMLE---PTITCFDEAQKKIFNLMEKDSYRRFLKSR 269 Query: 500 LYYKYLN 506 Y +N Sbjct: 270 FYLDLVN 276 >gi|85540441 regulator of G-protein signaling 21 [Homo sapiens] Length = 152 Score = 43.1 bits (100), Expect = 8e-04 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 10/124 (8%) Query: 383 ILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKY 442 +L ++ L F +++ E + ++FWLA ++F+ A K + A ++Y ++ Sbjct: 25 LLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTKNADK-------IASKAKMIYSEF 77 Query: 443 FSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYY 502 A + D R I NI P CF + + M K P FL S +Y Sbjct: 78 IEADAPKEINIDFGTRDLISKNIAE---PTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYK 134 Query: 503 KYLN 506 K +N Sbjct: 135 KLVN 138 Score = 31.2 bits (69), Expect = 3.2 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 294 IEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQ 353 I A ++++I DA K I I R D+I++ E CF AQ +++ M + Sbjct: 66 IASKAKMIYSEFIEADAPKEINIDFGTR-DLISKNIAEPTL---KCFDEAQKLIYCLMAK 121 Query: 354 EHFSEFLRSHHFCK 367 + F FL+S + K Sbjct: 122 DSFPRFLKSEIYKK 135 >gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens] Length = 211 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 10/120 (8%) Query: 382 DILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDK 441 ++L + L F +++ E ++FWLA ++F+ + +K + A +Y Sbjct: 86 ELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQK-------LSSKARKIYTD 138 Query: 442 YFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLY 501 + +A + D + I NI CFTT ++ ++ ME P FL S Y Sbjct: 139 FIEKEAPKEINIDFQTKTLIAQNIQEATS---GCFTTAQKRVYSLMENNSYPRFLESEFY 195 Score = 31.2 bits (69), Expect = 3.2 Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 289 KLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVF 348 K + + A +T +I +A K I I + I I + CF AQ V+ Sbjct: 123 KSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNI----QEATSGCFTTAQKRVY 178 Query: 349 SAMEQEHFSEFLRSHHF 365 S ME + FL S + Sbjct: 179 SLMENNSYPRFLESEFY 195 >gi|4506511 regulator of G-protein signalling 13 [Homo sapiens] Length = 159 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 ++ Y++ E + +QFW+A + ++ ++A++ + + A LY Y Q+ + Sbjct: 48 YAAYLKMEHSDENIQFWMACETYK-KIASRWSRI------SRAKKLYKIYIQPQSPREIN 100 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDL 508 D R I NI P CF + + ME+ P FL S +Y K L + Sbjct: 101 IDSSTRETIIRNIQE---PTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTM 153 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 305 YISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFLRSHH 364 YI P + + I I + R II I + CF AQ IV+ ME++ + FL+S Sbjct: 90 YIQPQSPREINIDSSTRETIIRNI----QEPTETCFEEAQKIVYMHMERDSYPRFLKSEM 145 Query: 365 FCK 367 + K Sbjct: 146 YQK 148 >gi|21464139 regulator of G-protein signalling 13 [Homo sapiens] Length = 159 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 ++ Y++ E + +QFW+A + ++ ++A++ + + A LY Y Q+ + Sbjct: 48 YAAYLKMEHSDENIQFWMACETYK-KIASRWSRI------SRAKKLYKIYIQPQSPREIN 100 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDL 508 D R I NI P CF + + ME+ P FL S +Y K L + Sbjct: 101 IDSSTRETIIRNIQE---PTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTM 153 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 305 YISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFLRSHH 364 YI P + + I I + R II I + CF AQ IV+ ME++ + FL+S Sbjct: 90 YIQPQSPREINIDSSTRETIIRNI----QEPTETCFEEAQKIVYMHMERDSYPRFLKSEM 145 Query: 365 FCK 367 + K Sbjct: 146 YQK 148 >gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo sapiens] Length = 1376 Score = 39.3 bits (90), Expect = 0.012 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 19/165 (11%) Query: 392 YFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPL 451 YFS+++ KE + + FW A + F A +D +E A ++ K+ +AT P+ Sbjct: 728 YFSDFLRKEFSEENILFWQACEYFNHVPA-----HDKKELSYRAREIFSKFLCSKATTPV 782 Query: 452 GFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS 511 D + ++ ++ R P P+ F Q + M+ FL S LY + ++ Sbjct: 783 NIDS--QAQLADDVLR--APHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC---ILAE 835 Query: 512 VRGDEFLGGNVSLTAPGSVGPPDESHPGSSDSSASQSSVKKASIK 556 V G S P S P H SD S S S+ KK S K Sbjct: 836 VEGRALPD---SQQVPSS---PASKHSLGSDHS-SVSTPKKLSGK 873 >gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo sapiens] Length = 1447 Score = 39.3 bits (90), Expect = 0.012 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 19/165 (11%) Query: 392 YFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPL 451 YFS+++ KE + + FW A + F A +D +E A ++ K+ +AT P+ Sbjct: 728 YFSDFLRKEFSEENILFWQACEYFNHVPA-----HDKKELSYRAREIFSKFLCSKATTPV 782 Query: 452 GFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS 511 D + ++ ++ R P P+ F Q + M+ FL S LY + ++ Sbjct: 783 NIDS--QAQLADDVLR--APHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC---ILAE 835 Query: 512 VRGDEFLGGNVSLTAPGSVGPPDESHPGSSDSSASQSSVKKASIK 556 V G S P S P H SD S S S+ KK S K Sbjct: 836 VEGRALPD---SQQVPSS---PASKHSLGSDHS-SVSTPKKLSGK 873 >gi|38327599 regulator of G-protein signalling 12 isoform 3 [Homo sapiens] Length = 799 Score = 39.3 bits (90), Expect = 0.012 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 19/165 (11%) Query: 392 YFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPL 451 YFS+++ KE + + FW A + F A +D +E A ++ K+ +AT P+ Sbjct: 80 YFSDFLRKEFSEENILFWQACEYFNHVPA-----HDKKELSYRAREIFSKFLCSKATTPV 134 Query: 452 GFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS 511 D + ++ ++ R P P+ F Q + M+ FL S LY + ++ Sbjct: 135 NIDS--QAQLADDVLR--APHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC---ILAE 187 Query: 512 VRGDEFLGGNVSLTAPGSVGPPDESHPGSSDSSASQSSVKKASIK 556 V G S P S P H SD S S S+ KK S K Sbjct: 188 VEGRALPD---SQQVPSS---PASKHSLGSDHS-SVSTPKKLSGK 225 >gi|13654235 regulator of G-protein signaling 20 isoform b [Homo sapiens] Length = 241 Score = 38.9 bits (89), Expect = 0.015 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F E++ E + + FW+A + K + + + A I+Y+ Y S+ + + Sbjct: 129 FREFLRTEFSEENMLFWMACEEL-------KKEANKNIIEEKARIIYEDYISILSPKEVS 181 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDL 508 D VR I N+ P + F Q +T M + P F++S +Y L L Sbjct: 182 LDSRVREVINRNMVE---PSQHIFDDAQLQIYTLMHRDSYPRFMNSAVYKDLLQSL 234 >gi|41281805 regulator of G-protein signaling 20 isoform a [Homo sapiens] Length = 388 Score = 38.9 bits (89), Expect = 0.015 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F E++ E + + FW+A + K + + + A I+Y+ Y S+ + + Sbjct: 276 FREFLRTEFSEENMLFWMACEEL-------KKEANKNIIEEKARIIYEDYISILSPKEVS 328 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDL 508 D VR I N+ P + F Q +T M + P F++S +Y L L Sbjct: 329 LDSRVREVINRNMVE---PSQHIFDDAQLQIYTLMHRDSYPRFMNSAVYKDLLQSL 381 >gi|24797143 sorting nexin 14 isoform b [Homo sapiens] Length = 893 Score = 38.1 bits (87), Expect = 0.026 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 24/134 (17%) Query: 387 ESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMI--------L 438 + LF F ++++E AV++LQF L + F ++ E ND M+ + Sbjct: 300 QDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRP-------ELSNDEMLSLHEELQKI 352 Query: 439 YDKYFSLQATHPLGFDDVVRLEIESNICREGGPLP-------NCFTTPLRQAWTTMEKVF 491 Y Y ++ + FD + EI+ EG + C + +E VF Sbjct: 353 YKTYCLDESIDKIRFDPFIVEEIQR--IAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVF 410 Query: 492 LPGFLSSNLYYKYL 505 P F S+ Y++ L Sbjct: 411 TPMFCHSDEYFRQL 424 >gi|24797145 sorting nexin 14 isoform a [Homo sapiens] Length = 946 Score = 38.1 bits (87), Expect = 0.026 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 24/134 (17%) Query: 387 ESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMI--------L 438 + LF F ++++E AV++LQF L + F ++ E ND M+ + Sbjct: 344 QDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRP-------ELSNDEMLSLHEELQKI 396 Query: 439 YDKYFSLQATHPLGFDDVVRLEIESNICREGGPLP-------NCFTTPLRQAWTTMEKVF 491 Y Y ++ + FD + EI+ EG + C + +E VF Sbjct: 397 YKTYCLDESIDKIRFDPFIVEEIQR--IAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVF 454 Query: 492 LPGFLSSNLYYKYL 505 P F S+ Y++ L Sbjct: 455 TPMFCHSDEYFRQL 468 >gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] Length = 1233 Score = 37.7 bits (86), Expect = 0.034 Identities = 50/219 (22%), Positives = 80/219 (36%), Gaps = 25/219 (11%) Query: 18 DPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNHALLEAAGPSHVAINAIS 77 D M R+K+ G +E T K + A I QK + H LL+A + + Sbjct: 886 DKNHEMEEIRKKLGGANKEMTHLQKEVTA-IETKLEQKRSDRHNLLQACKMQDIKLPLSK 944 Query: 78 ANMDSFS--------------SSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLS 123 MD S S R +++ + + +E +GDL D Q +E Sbjct: 945 GTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEI-DYGDLCEDLKDAQAEEEIKQEM 1003 Query: 124 KTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLA 183 TL+Q L++ + I ++ ME L + F T+ A K Sbjct: 1004 NTLQQKLNEQQSVLQRIAAPNMKAMEKLESV---RDKFQETS-DEFEAARKRAKKAKQAF 1059 Query: 184 EPVSPSKKHETTASFLT-----DSLDKRLEDSGSAQLFM 217 E + + A F + D + K L + SAQ F+ Sbjct: 1060 EQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFL 1098 >gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo sapiens] Length = 198 Score = 37.4 bits (85), Expect = 0.045 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 10/114 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F +++ E + L+FWLA + F+ + K + A +++++ +QA + Sbjct: 88 FRAFLKTEFSEENLEFWLACEEFKKTRSTAK-------LVSKAHRIFEEFVDVQAPREVN 140 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLN 506 D R N+ P CF + + MEK P FL S +Y L+ Sbjct: 141 IDFQTREATRKNLQE---PSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLS 191 >gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo sapiens] Length = 180 Score = 37.4 bits (85), Expect = 0.045 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 10/114 (8%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F +++ E + L+FWLA + F+ + K + A +++++ +QA + Sbjct: 70 FRAFLKTEFSEENLEFWLACEEFKKTRSTAK-------LVSKAHRIFEEFVDVQAPREVN 122 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLN 506 D R N+ P CF + + MEK P FL S +Y L+ Sbjct: 123 IDFQTREATRKNLQE---PSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLS 173 >gi|51873049 hypothetical protein LOC8603 [Homo sapiens] Length = 1224 Score = 35.0 bits (79), Expect = 0.22 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 13/99 (13%) Query: 473 PNCF-TTPLRQAWTTMEKVFLPGFLSSNLYYKYLND---LIHSVRGDEFLGGNVSLTAPG 528 P+CF TP W + + + L G S + K N L ++ G E LG +S T P Sbjct: 513 PSCFGNTP---EWNSSKFISLWG--SEVMNDKNWNPGTFLPDTISGSEILGPTLSETRPE 567 Query: 529 SVGPPDESH-PGSSDSSASQSSVKKASIKILKNFDEAII 566 ++ PP + P SDS +++ KK K L NF +A + Sbjct: 568 ALPPPSSNETPAVSDSKEKKNAAKK---KCLYNFQDAFM 603 >gi|86990435 G protein signalling regulator 19 [Homo sapiens] Length = 217 Score = 34.7 bits (78), Expect = 0.29 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F ++ E + + FWLA + +L A+ Q+ E A ++Y+ Y S+ + + Sbjct: 104 FRAFLRTEYSEENMLFWLACE----ELKAEANQHVVDEK---ARLIYEDYVSILSPKEVS 156 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLY 501 D VR I + P + F Q +T M + P FLSS Y Sbjct: 157 LDSRVREGINKKMQE---PSAHTFDDAQLQIYTLMHRDSYPRFLSSPTY 202 >gi|5031705 G protein signalling regulator 19 [Homo sapiens] Length = 217 Score = 34.7 bits (78), Expect = 0.29 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 393 FSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLG 452 F ++ E + + FWLA + +L A+ Q+ E A ++Y+ Y S+ + + Sbjct: 104 FRAFLRTEYSEENMLFWLACE----ELKAEANQHVVDEK---ARLIYEDYVSILSPKEVS 156 Query: 453 FDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLY 501 D VR I + P + F Q +T M + P FLSS Y Sbjct: 157 LDSRVREGINKKMQE---PSAHTFDDAQLQIYTLMHRDSYPRFLSSPTY 202 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.128 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,966,455 Number of Sequences: 37866 Number of extensions: 1087648 Number of successful extensions: 4285 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 4176 Number of HSP's gapped (non-prelim): 157 length of query: 662 length of database: 18,247,518 effective HSP length: 109 effective length of query: 553 effective length of database: 14,120,124 effective search space: 7808428572 effective search space used: 7808428572 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.