BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 2 [Homo sapiens] (254 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is... 499 e-142 gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 i... 499 e-142 gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is... 228 4e-60 gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is... 228 4e-60 gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is... 228 4e-60 gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is... 226 1e-59 gi|46409302 NIPA-like domain containing 1 [Homo sapiens] 225 3e-59 gi|149944536 ichthyin protein [Homo sapiens] 209 1e-54 gi|10092687 NIPA-like domain containing 3 [Homo sapiens] 94 1e-19 gi|13376097 NIPA-like domain containing 2 [Homo sapiens] 86 4e-17 gi|4504779 integrin, beta 8 precursor [Homo sapiens] 33 0.18 >gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 1 [Homo sapiens] Length = 329 Score = 499 bits (1285), Expect = e-142 Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV Sbjct: 76 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 135 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC Sbjct: 136 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 195 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF Sbjct: 196 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 255 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN Sbjct: 256 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 315 Query: 241 FNLGEMNKSNMKTD 254 FNLGEMNKSNMKTD Sbjct: 316 FNLGEMNKSNMKTD 329 >gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 2 [Homo sapiens] Length = 254 Score = 499 bits (1285), Expect = e-142 Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV Sbjct: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC Sbjct: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF Sbjct: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN Sbjct: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 Query: 241 FNLGEMNKSNMKTD 254 FNLGEMNKSNMKTD Sbjct: 241 FNLGEMNKSNMKTD 254 >gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 228 bits (581), Expect = 4e-60 Identities = 113/254 (44%), Positives = 169/254 (66%), Gaps = 2/254 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 M G++ NF AY P LVTPLGAL V +IL+SY L E+LN+ GK+GCLLS GS V Sbjct: 66 MGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTV 125 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+PK E + T E+ KL +P FV + +V+++ L+LIF + P HG TNI+VYI+IC Sbjct: 126 MVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITIC 185 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 S++G+F+V KG+G+A +++ P + L ++LL+++ C + Q Y+N+AL+ F Sbjct: 186 SVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA-WILLLSLIVC-VSTQINYLNRALDIF 243 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FTT VL SAILF+EW ++ + D +G GF T+ VGI L+ FK+ + Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVS 303 Query: 241 FNLGEMNKSNMKTD 254 F+L + S K + Sbjct: 304 FSLASLPVSFRKDE 317 >gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 228 bits (581), Expect = 4e-60 Identities = 113/254 (44%), Positives = 169/254 (66%), Gaps = 2/254 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 M G++ NF AY P LVTPLGAL V +IL+SY L E+LN+ GK+GCLLS GS V Sbjct: 66 MGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTV 125 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+PK E + T E+ KL +P FV + +V+++ L+LIF + P HG TNI+VYI+IC Sbjct: 126 MVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITIC 185 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 S++G+F+V KG+G+A +++ P + L ++LL+++ C + Q Y+N+AL+ F Sbjct: 186 SVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA-WILLLSLIVC-VSTQINYLNRALDIF 243 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FTT VL SAILF+EW ++ + D +G GF T+ VGI L+ FK+ + Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVS 303 Query: 241 FNLGEMNKSNMKTD 254 F+L + S K + Sbjct: 304 FSLASLPVSFRKDE 317 >gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 228 bits (581), Expect = 4e-60 Identities = 113/254 (44%), Positives = 169/254 (66%), Gaps = 2/254 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 M G++ NF AY P LVTPLGAL V +IL+SY L E+LN+ GK+GCLLS GS V Sbjct: 66 MGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTV 125 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+PK E + T E+ KL +P FV + +V+++ L+LIF + P HG TNI+VYI+IC Sbjct: 126 MVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITIC 185 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 S++G+F+V KG+G+A +++ P + L ++LL+++ C + Q Y+N+AL+ F Sbjct: 186 SVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA-WILLLSLIVC-VSTQINYLNRALDIF 243 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FTT VL SAILF+EW ++ + D +G GF T+ VGI L+ FK+ + Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVS 303 Query: 241 FNLGEMNKSNMKTD 254 F+L + S K + Sbjct: 304 FSLASLPVSFRKDE 317 >gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 isoform b [Homo sapiens] Length = 341 Score = 226 bits (577), Expect = 1e-59 Identities = 112/254 (44%), Positives = 169/254 (66%), Gaps = 2/254 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 + G++ NF AY P LVTPLGAL V +IL+SY L E+LN+ GK+GCLLS GS V Sbjct: 47 VGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTV 106 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+PK E + T E+ KL +P FV + +V+++ L+LIF + P HG TNI+VYI+IC Sbjct: 107 MVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITIC 166 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 S++G+F+V KG+G+A +++ P + L ++LL+++ C + Q Y+N+AL+ F Sbjct: 167 SVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA-WILLLSLIVC-VSTQINYLNRALDIF 224 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FTT VL SAILF+EW ++ + D +G GF T+ VGI L+ FK+ + Sbjct: 225 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVS 284 Query: 241 FNLGEMNKSNMKTD 254 F+L + S K + Sbjct: 285 FSLASLPVSFRKDE 298 >gi|46409302 NIPA-like domain containing 1 [Homo sapiens] Length = 410 Score = 225 bits (574), Expect = 3e-59 Identities = 115/252 (45%), Positives = 163/252 (64%), Gaps = 2/252 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 M G+ NF AY P LVTPLGAL V +IL+SY L E LNI GK+GC+LS GS V Sbjct: 124 MGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTV 183 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+P+ E VT+ E+E KL +P F+ + I+ ++ L+LI +AP G TNI+VYISIC Sbjct: 184 MVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYISIC 243 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 SL+G+F+V S KG+G+A ++++ P + L VLLAVL S+ Q Y+NKAL+ F Sbjct: 244 SLIGAFSVSSVKGLGIAIKELIEWKPVYKHP--LVFVLLAVLVLSVTTQINYLNKALDTF 301 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FT++V+ SAILF+EW + D +G GF T+ +GI L+ FK + Sbjct: 302 NTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKNTD 361 Query: 241 FNLGEMNKSNMK 252 E+ + K Sbjct: 362 ITWSELTSTAKK 373 >gi|149944536 ichthyin protein [Homo sapiens] Length = 466 Score = 209 bits (533), Expect = 1e-54 Identities = 101/246 (41%), Positives = 160/246 (65%), Gaps = 2/246 (0%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 MA G++ NF AY P +VTPLGAL V +IL+SY L+E LN+LGKLGC++ AGS V Sbjct: 174 MAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTV 233 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 ++IH+P+ E VTT E+ K+ + F+ + ++L+ L+LIF IAP +G NI++YI IC Sbjct: 234 MVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIIC 293 Query: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180 S++G+F+V + KG+G+ ++ P + L L L +L S+ Q ++N+AL+ F Sbjct: 294 SVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSL--ILALSLSTQVNFLNRALDIF 351 Query: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240 ++S+ IYYV FTT+V+ +S ILF+EW ++ VD G GF T+ +G+ ++ FK+ + Sbjct: 352 NTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLD 411 Query: 241 FNLGEM 246 + + Sbjct: 412 ISCASL 417 >gi|10092687 NIPA-like domain containing 3 [Homo sapiens] Length = 406 Score = 94.0 bits (232), Expect = 1e-19 Identities = 59/241 (24%), Positives = 120/241 (49%), Gaps = 11/241 (4%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLN--------ILGKLGCL 52 M +G++G F +Y P L+ PL A+ V +I+ +KEK +L +GC Sbjct: 83 MLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCG 142 Query: 53 LSCAGSVVLIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTN 112 L+ G+ +L+ +P S T + L + F+ Y+ + +++ LL+++ + N Sbjct: 143 LAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NN 201 Query: 113 IMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRY 172 I+V + + +LLGS TV + K + A +L + Q + V+ + + + Q + Sbjct: 202 IVVILLLVALLGSMTVVTVKAV--AGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAF 259 Query: 173 INKALECFDSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVL 232 +++A + +DSS+ ++ Y++ TT+ + A AI + ++ ++ A G +G+ L Sbjct: 260 LSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFL 319 Query: 233 I 233 I Sbjct: 320 I 320 >gi|13376097 NIPA-like domain containing 2 [Homo sapiens] Length = 368 Score = 85.5 bits (210), Expect = 4e-17 Identities = 49/209 (23%), Positives = 109/209 (52%), Gaps = 5/209 (2%) Query: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60 MAVG+ GNF AY P L+ PLG + V +I++ LK+ L LG L+ AG+ + Sbjct: 97 MAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYL 156 Query: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120 L+ +P + ++ L F+ Y+ + +L+ +L+++ G ++++ +++ Sbjct: 157 LVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLV 215 Query: 121 SLLGSFTVPSTKGI-GLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALEC 179 ++L S TV S K + G+ ++ Q + ++ ++ S + Q +++N+A + Sbjct: 216 AILASLTVISVKAVSGMITFSVM---DKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKL 272 Query: 180 FDSSVFGAIYYVVFTTLVLLASAILFREW 208 ++++ + ++ FT ++A I ++E+ Sbjct: 273 YNTTTVVPVNHIFFTISAIIAGIIFYQEF 301 >gi|4504779 integrin, beta 8 precursor [Homo sapiens] Length = 769 Score = 33.5 bits (75), Expect = 0.18 Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 7/68 (10%) Query: 142 LHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAIYYVVF--TTLVLL 199 LH + SQ L C C+++ Q Y+++ ECF S + I++++F T L+ L Sbjct: 644 LHPHNLSQAILDQCKT-----SCALMEQQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGL 698 Query: 200 ASAILFRE 207 ++ R+ Sbjct: 699 LKVLIIRQ 706 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.142 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,535,773 Number of Sequences: 37866 Number of extensions: 337242 Number of successful extensions: 1014 Number of sequences better than 10.0: 11 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 990 Number of HSP's gapped (non-prelim): 11 length of query: 254 length of database: 18,247,518 effective HSP length: 100 effective length of query: 154 effective length of database: 14,460,918 effective search space: 2226981372 effective search space used: 2226981372 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.