BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|11386147 prosaposin isoform a preproprotein [Homo sapiens] (524 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|11386147 prosaposin isoform a preproprotein [Homo sapiens] 1078 0.0 gi|110224479 prosaposin isoform c preproprotein [Homo sapiens] 1073 0.0 gi|110224476 prosaposin isoform b preproprotein [Homo sapiens] 1073 0.0 gi|145977198 prosaposin-like protein 1 [Homo sapiens] 456 e-128 gi|38504667 surfactant, pulmonary-associated protein B [Homo sap... 102 7e-22 gi|33943099 surfactant, pulmonary-associated protein B [Homo sap... 102 7e-22 gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens] 40 0.004 gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ... 38 0.020 gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s... 38 0.026 gi|39812027 amino-terminal enhancer of split isoform c [Homo sap... 35 0.22 gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2... 34 0.37 gi|156139127 hypothetical protein LOC80007 [Homo sapiens] 34 0.37 gi|39812019 amino-terminal enhancer of split isoform a [Homo sap... 33 0.49 gi|5706731 amino-terminal enhancer of split isoform b [Homo sapi... 33 0.49 gi|194473700 Src homology 3 domain-containing guanine nucleotide... 33 0.83 gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 32 1.1 gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 32 1.1 gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] 32 1.1 gi|41281907 StAR-related lipid transfer (START) domain containin... 32 1.9 gi|7657671 upstream binding transcription factor, RNA polymerase... 32 1.9 gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 32 1.9 gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 31 2.4 gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 31 2.4 gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 31 2.4 gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 31 3.2 gi|162287219 prune homolog 2 [Homo sapiens] 30 4.1 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 30 4.1 gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 30 4.1 gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 30 5.4 gi|7108344 granulysin isoform NKG5 [Homo sapiens] 30 5.4 >gi|11386147 prosaposin isoform a preproprotein [Homo sapiens] Length = 524 Score = 1078 bits (2789), Expect = 0.0 Identities = 524/524 (100%), Positives = 524/524 (100%) Query: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS Sbjct: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 Query: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI Sbjct: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 Query: 241 CKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVE 300 CKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVE Sbjct: 241 CKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVE 300 Query: 301 PIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV 360 PIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV Sbjct: 301 PIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV 360 Query: 361 VDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLD 420 VDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLD Sbjct: 361 VDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLD 420 Query: 421 RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIG 480 RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIG Sbjct: 421 RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIG 480 Query: 481 ACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524 ACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN Sbjct: 481 ACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524 >gi|110224479 prosaposin isoform c preproprotein [Homo sapiens] Length = 526 Score = 1073 bits (2776), Expect = 0.0 Identities = 524/526 (99%), Positives = 524/526 (99%), Gaps = 2/526 (0%) Query: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS Sbjct: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 Query: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI Sbjct: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 Query: 241 CKNYISQYSEIAIQMMMHM--QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 298 CKNYISQYSEIAIQMMMHM QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL Sbjct: 241 CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 300 Query: 299 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 358 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ Sbjct: 301 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 360 Query: 359 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 418 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY Sbjct: 361 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 420 Query: 419 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 478 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK Sbjct: 421 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 480 Query: 479 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN Sbjct: 481 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526 >gi|110224476 prosaposin isoform b preproprotein [Homo sapiens] Length = 527 Score = 1073 bits (2775), Expect = 0.0 Identities = 524/527 (99%), Positives = 524/527 (99%), Gaps = 3/527 (0%) Query: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS Sbjct: 1 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60 Query: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI Sbjct: 61 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120 Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180 Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 Query: 241 CKNYISQYSEIAIQMMMHMQ---PKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 297 CKNYISQYSEIAIQMMMHMQ PKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE Sbjct: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300 Query: 298 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 357 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC Sbjct: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360 Query: 358 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 417 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG Sbjct: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420 Query: 418 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 477 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL Sbjct: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480 Query: 478 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN Sbjct: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527 >gi|145977198 prosaposin-like protein 1 [Homo sapiens] Length = 521 Score = 456 bits (1173), Expect = e-128 Identities = 236/532 (44%), Positives = 334/532 (62%), Gaps = 36/532 (6%) Query: 3 ALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLP 62 AL LL SLLGA A P G +EC +GS VWCQ+++TA+ CGAV +C VWNKPT KSLP Sbjct: 4 ALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNKPTAKSLP 63 Query: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122 CD+C+D+ AAG+ L +ATE +IL + KTC+WLP SA CK +VD++ IL +++ Sbjct: 64 CDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLR 123 Query: 123 GEM-SRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181 G S P +VC+AL+LCE LQ+HLA L + + D E VAPFMAN PL +P Sbjct: 124 GAPDSAPAQVCTALSLCEPLQRHLATLR--------PLSKEDTFEAVAPFMANGPLTFHP 175 Query: 182 QDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADIC 241 + P G +CQDC++ V+ +Q AVR+N T +++E+C+ LGPG+A +C Sbjct: 176 RQAPE--------GALCQDCVRQVSRLQEAVRSNLTLADL---NIQEQCESLGPGLAVLC 224 Query: 242 KNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEP 301 KNY+ Q+ A Q + + P+E+C GFC+E+ T +V + + +P+LEL P Sbjct: 225 KNYLFQFFVPADQALRLLPPQELCRKGGFCEELGAPARLT----QVVAMDGVPSLELGLP 280 Query: 302 IKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVV 361 K+ E+ K+ V CEVC +V+++ + +N +E I A +++CS +P S+++EC +V Sbjct: 281 RKQSEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILV 340 Query: 362 DTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH-----VTQPK-----DGGFCEV 411 DTY S++ L+ +++PE VC + LC G R A VH V P+ G FC Sbjct: 341 DTYSPSLVQ-LVAKITPEKVCKFIRLC-GNRRRARAVHDAYAIVPSPEWDAENQGSFCNG 398 Query: 412 CKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMD 471 CK+L+ NLE STK++IL A + GCS LP PY QC FV +YEPVLIE L ++MD Sbjct: 399 CKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMD 458 Query: 472 PSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523 P VC K+GAC PLLGT++C GPS+WC++ E A CNAV+HC++HVW Sbjct: 459 PVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVW 510 Score = 45.8 bits (107), Expect = 9e-05 Identities = 17/37 (45%), Positives = 25/37 (67%) Query: 488 PLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524 P G ++C G + WCQ+ +TAA+C AV +C+ VWN Sbjct: 19 PTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWN 55 Score = 42.7 bits (99), Expect = 8e-04 Identities = 15/38 (39%), Positives = 24/38 (63%) Query: 18 PVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK 55 P+LG +C G + WC++ + A C AV+HC + VW + Sbjct: 475 PLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVWKE 512 >gi|38504667 surfactant, pulmonary-associated protein B [Homo sapiens] Length = 381 Score = 102 bits (255), Expect = 7e-22 Identities = 92/410 (22%), Positives = 165/410 (40%), Gaps = 53/410 (12%) Query: 2 YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61 + L LL +L G A C +G WCQ+++ A C A+ HCLQ VW L Sbjct: 9 WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68 Query: 62 PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121 C C+D+V M K+ ++ + +LE+ C+ LP + C +++D Y P+++D Sbjct: 69 -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127 Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181 + + G +C L LC+S Q Q+ S+ +P+ + P + + L + P Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182 Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232 + GP ++ + + C C ++ IQ + AL V + C Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237 Query: 233 LGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFCDEVKEMPMQTLVPAKVASKN 291 + IC+ +YS I + ++ M P+ +C LV C M + + Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCS------MDDSAGPRSPTGE 291 Query: 292 VIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--SKL 349 +P D C +C + + N +E+ I A + C S L Sbjct: 292 WLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGSWL 330 Query: 350 PKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 399 + E+C++ V+ + +L+++ C L +C P +H Sbjct: 331 DR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377 Score = 71.2 bits (173), Expect = 2e-12 Identities = 74/333 (22%), Positives = 134/333 (40%), Gaps = 49/333 (14%) Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254 D+CQ+C +V I + + F + + +++EC+ L + C + Y + I Sbjct: 67 DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125 Query: 255 MMMHMQPKE-ICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALELVE 300 + IC +G C + P++ +P + K V+P L Sbjct: 126 YFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP--G 183 Query: 301 PIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350 ++ P D+ YC +C L+K + +I + A ++C +P Sbjct: 184 ALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRVVP 239 Query: 351 KSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDGGF 408 CQ + + Y +L LL + P+LVC ++ CS + P P+D Sbjct: 240 LVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSE- 298 Query: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIEIL 466 C +C + NS++Q I A+ + C S+L +++C QFV ++ P L+ ++ Sbjct: 299 CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLTLV 350 Query: 467 VEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 499 D C +G C + PL +CI P Sbjct: 351 PRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379 Score = 43.9 bits (102), Expect = 4e-04 Identities = 15/29 (51%), Positives = 19/29 (65%) Query: 495 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 523 C GP +WCQ+ E A QC A+ HC + VW Sbjct: 32 CAQGPEFWCQSLEQALQCRALGHCLQEVW 60 >gi|33943099 surfactant, pulmonary-associated protein B [Homo sapiens] Length = 381 Score = 102 bits (255), Expect = 7e-22 Identities = 92/410 (22%), Positives = 165/410 (40%), Gaps = 53/410 (12%) Query: 2 YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61 + L LL +L G A C +G WCQ+++ A C A+ HCLQ VW L Sbjct: 9 WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68 Query: 62 PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121 C C+D+V M K+ ++ + +LE+ C+ LP + C +++D Y P+++D Sbjct: 69 -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127 Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181 + + G +C L LC+S Q Q+ S+ +P+ + P + + L + P Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182 Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232 + GP ++ + + C C ++ IQ + AL V + C Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237 Query: 233 LGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFCDEVKEMPMQTLVPAKVASKN 291 + IC+ +YS I + ++ M P+ +C LV C M + + Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCS------MDDSAGPRSPTGE 291 Query: 292 VIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--SKL 349 +P D C +C + + N +E+ I A + C S L Sbjct: 292 WLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGSWL 330 Query: 350 PKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 399 + E+C++ V+ + +L+++ C L +C P +H Sbjct: 331 DR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377 Score = 71.2 bits (173), Expect = 2e-12 Identities = 74/333 (22%), Positives = 134/333 (40%), Gaps = 49/333 (14%) Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254 D+CQ+C +V I + + F + + +++EC+ L + C + Y + I Sbjct: 67 DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125 Query: 255 MMMHMQPKE-ICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALELVE 300 + IC +G C + P++ +P + K V+P L Sbjct: 126 YFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP--G 183 Query: 301 PIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350 ++ P D+ YC +C L+K + +I + A ++C +P Sbjct: 184 ALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRVVP 239 Query: 351 KSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDGGF 408 CQ + + Y +L LL + P+LVC ++ CS + P P+D Sbjct: 240 LVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSE- 298 Query: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIEIL 466 C +C + NS++Q I A+ + C S+L +++C QFV ++ P L+ ++ Sbjct: 299 CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLTLV 350 Query: 467 VEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 499 D C +G C + PL +CI P Sbjct: 351 PRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379 Score = 43.9 bits (102), Expect = 4e-04 Identities = 15/29 (51%), Positives = 19/29 (65%) Query: 495 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 523 C GP +WCQ+ E A QC A+ HC + VW Sbjct: 32 CAQGPEFWCQSLEQALQCRALGHCLQEVW 60 >gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens] Length = 575 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 6/77 (7%) Query: 315 CEVCEFLVKEVTKLID-NNKTEKEILDAFDKMCSKLPKSL--SEECQEVVDTYGSSILSI 371 C C +V + +L +N T + + +++CS LP+ L C V+D +GS I+ + Sbjct: 41 CVGCVLVVSVIEQLAQVHNST---VQASMERLCSYLPEKLFLKTTCYLVIDKFGSDIIKL 97 Query: 372 LLEEVSPELVCSMLHLC 388 L +++ ++VC L C Sbjct: 98 LSADMNADVVCHTLEFC 114 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 7/107 (6%) Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG--MA 238 P + +S+P NG C C+ +V+ I+ + +++ VQA +E + C L + Sbjct: 25 PANDDQSRPS-LSNGHTCVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEKLFLK 80 Query: 239 DICKNYISQY-SEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVP 284 C I ++ S+I + M +C + FC + P+ L P Sbjct: 81 TTCYLVIDKFGSDIIKLLSADMNADVVCHTLEFCKQNTGQPLCHLYP 127 >gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo sapiens] Length = 706 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 16/140 (11%) Query: 182 QDGPRSKPQ-PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240 QD P S Q P +G + I + D ++ F+QA +K EC++L ++ Sbjct: 13 QDSPASGLQTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKTEM 69 Query: 241 CKNYISQYS-EIAIQMMMHMQPKEICALVGFCDEV--------KEMPMQTLVPAK---VA 288 ++Y+ Y + + MH Q + + L G C ++ ++ +Q + AK V Sbjct: 70 QRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVG 129 Query: 289 SKNVIPALELVEPIKKHEVP 308 N + + ++P+ H P Sbjct: 130 ELNSLIGQQQLQPLSHHAPP 149 >gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo sapiens] Length = 743 Score = 37.7 bits (86), Expect = 0.026 Identities = 30/141 (21%), Positives = 62/141 (43%), Gaps = 17/141 (12%) Query: 179 LYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA 238 +YPQ P P +G + I + D ++ F+QA +K EC++L Sbjct: 1 MYPQG---RHPTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKT 54 Query: 239 DICKNYISQYS-EIAIQMMMHMQPKEICALVGFCDEV--------KEMPMQTLVPAKVAS 289 ++ ++Y+ Y + + MH Q + + L G C ++ ++ +Q + AK + Sbjct: 55 EMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVT 114 Query: 290 KNVIPAL--ELVEPIKKHEVP 308 + +L + ++P+ H P Sbjct: 115 VGELNSLIGQQLQPLSHHAPP 135 >gi|39812027 amino-terminal enhancer of split isoform c [Homo sapiens] Length = 196 Score = 34.7 bits (78), Expect = 0.22 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Query: 189 PQPKDNGD--VCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246 PQ + +G + Q +D ++ +QA +K ECD+L +++ ++Y+ Sbjct: 4 PQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVM 63 Query: 247 QYS-EIAIQMMMHMQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKNVIPAL-ELV 299 Y + + MH Q + + L G C +V +E Q L + A + P L ++ Sbjct: 64 YYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSII 123 Query: 300 EPIKKHEV 307 ++ H++ Sbjct: 124 RQLQAHQL 131 >gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2 [Homo sapiens] Length = 492 Score = 33.9 bits (76), Expect = 0.37 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%) Query: 114 LPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMA 173 LP L I +MSRP V ESLQK + L ++ ++ KIP M E+ F+ Sbjct: 128 LPETLVIFVADMSRPWTVM------ESLQKWASVL--REHIDKMKIPPEKMRELERKFVK 179 Query: 174 NIPLLLYPQDGPRSKPQ 190 + + P++G + PQ Sbjct: 180 DFQDYMEPEEGCQGSPQ 196 >gi|156139127 hypothetical protein LOC80007 [Homo sapiens] Length = 445 Score = 33.9 bits (76), Expect = 0.37 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%) Query: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 366 ++D+ + FL K+V+ ++N E+L +CS+ L ECQE + +G Sbjct: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362 Query: 367 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 425 IL + +EE S +CS L + + KKL+ Y+D+ + + Sbjct: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403 >gi|39812019 amino-terminal enhancer of split isoform a [Homo sapiens] Length = 264 Score = 33.5 bits (75), Expect = 0.49 Identities = 28/138 (20%), Positives = 59/138 (42%), Gaps = 8/138 (5%) Query: 178 LLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGM 237 L + + G R + + + Q +D ++ +QA +K ECD+L Sbjct: 62 LFFDRWGNRGPAGCRGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEK 121 Query: 238 ADICKNYISQYS-EIAIQMMMHMQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKN 291 +++ ++Y+ Y + + MH Q + + L G C +V +E Q L + A + Sbjct: 122 SEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQV 181 Query: 292 VIPALELV--EPIKKHEV 307 P L + + ++ H++ Sbjct: 182 TAPELNSIIRQQLQAHQL 199 >gi|5706731 amino-terminal enhancer of split isoform b [Homo sapiens] Length = 197 Score = 33.5 bits (75), Expect = 0.49 Identities = 28/129 (21%), Positives = 57/129 (44%), Gaps = 10/129 (7%) Query: 189 PQPKDNGD--VCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246 PQ + +G + Q +D ++ +QA +K ECD+L +++ ++Y+ Sbjct: 4 PQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVM 63 Query: 247 QYS-EIAIQMMMHMQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKNVIPALELV- 299 Y + + MH Q + + L G C +V +E Q L + A + P L + Sbjct: 64 YYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSII 123 Query: 300 -EPIKKHEV 307 + ++ H++ Sbjct: 124 RQQLQAHQL 132 >gi|194473700 Src homology 3 domain-containing guanine nucleotide exchange factor [Homo sapiens] Length = 871 Score = 32.7 bits (73), Expect = 0.83 Identities = 29/136 (21%), Positives = 62/136 (45%), Gaps = 9/136 (6%) Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQM 255 DVC+ + +++ A N+ F+ + + V++ C N + Y + +Q Sbjct: 489 DVCEASKKFFIELE-ARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEV--YQQRTLQK 545 Query: 256 MMHMQP--KEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDV 313 ++ P KE+ + + ++ + +PM + + + + L L+ + P S Sbjct: 546 LLATNPSFKEVLSRIESHEDCRNLPMISFL---ILPMQRVTRLPLLMDTICQKTPKDSPK 602 Query: 314 YCEVCEFLVKEVTKLI 329 Y EVC+ +KEV+KL+ Sbjct: 603 Y-EVCKRALKEVSKLV 617 >gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] Length = 1184 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 477 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 518 LK G C + +GT C P + CQNT+ + C A + C Sbjct: 757 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 796 >gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] Length = 1231 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 477 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 518 LK G C + +GT C P + CQNT+ + C A + C Sbjct: 804 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 843 >gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] Length = 5183 Score = 32.3 bits (72), Expect = 1.1 Identities = 37/177 (20%), Positives = 72/177 (40%), Gaps = 16/177 (9%) Query: 143 KHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCI 202 K L+++ QK+L S PEL EV F+ + + P+ S+P ++ Sbjct: 165 KTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRT-VASQPISTQTLVEGENDE 223 Query: 203 QMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG--MADICKN------YISQYSEIAIQ 254 Q TD +A++T + F+ V ++E LG + +C N YI+++ + + Sbjct: 224 QSSTDQASAIKTKNVFIAQNVASLQE----LGGSEKLLRVCLNLPYFLRYINRFQDAVLA 279 Query: 255 MMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKS 311 + P + + + + + S +P LE + P + +V S Sbjct: 280 NSFFIMPATVADATAVRNGFHSLVIDVTMALDTLS---LPVLEPLNPSRLQDVTVLS 333 >gi|41281907 StAR-related lipid transfer (START) domain containing 13 isoform beta [Homo sapiens] Length = 1105 Score = 31.6 bits (70), Expect = 1.9 Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%) Query: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122 C CKD V + N T + + ++ CDWL + DS P+ + +K Sbjct: 25 CRECKDTVCGGKQKSRVNHTFQRREIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVK 84 Query: 123 G-----EMSRPGEVCSALNLCESLQKHLAELNHQKQ 153 E +C LN ++N Q++ Sbjct: 85 NDHDFLEKDLVEPLCRRLNTLNKCASMKLDVNFQRK 120 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 31.6 bits (70), Expect = 1.9 Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 24/186 (12%) Query: 297 ELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP------ 350 +L++ KK ++P K ++ K+V + + T KE+ D+ K S+L Sbjct: 185 DLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLK 244 Query: 351 ---KSLSE--ECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKD 405 K+L + E +E++ Y + + E + S L T+P Sbjct: 245 WIHKALEQRKEYEEIMRDYIQKHPELNISEEG--ITKSTLTKAERQLKDKFDGRPTKPPP 302 Query: 406 GGFCEVCKKLVGYLD-----RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEP 460 + C +L+ + + S + ++L+ EK D Y K+CDQ +YE Sbjct: 303 NSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEK------DAYHKKCDQKKKDYEV 356 Query: 461 VLIEIL 466 L+ L Sbjct: 357 ELLRFL 362 >gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] Length = 773 Score = 31.6 bits (70), Expect = 1.9 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 15/124 (12%) Query: 179 LYPQDGPRSKPQPKD--NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG 236 +YPQ + QP + + C ++ + Q F+QA +K EC++L Sbjct: 8 MYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQ--------FLQAQYHSLKLECEKLASE 59 Query: 237 MADICKNYISQYS-EIAIQMMMHMQPKEICALVGFCDEV----KEMPMQTLVPAKVASKN 291 ++ ++Y+ Y + + MH Q + + L C +V + Q +V A +K Sbjct: 60 KTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQ 119 Query: 292 VIPA 295 V A Sbjct: 120 VTMA 123 >gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] Length = 1164 Score = 31.2 bits (69), Expect = 2.4 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%) Query: 307 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 365 V + + CE + V +V K D + DA CS L + L + Q + D+ Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567 Query: 366 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 421 + +L +++EE + V S G L VT+P +K V + Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617 Query: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452 L NS K+ + +E+ + DP C+ Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648 >gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] Length = 1220 Score = 31.2 bits (69), Expect = 2.4 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%) Query: 307 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 365 V + + CE + V +V K D + DA CS L + L + Q + D+ Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567 Query: 366 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 421 + +L +++EE + V S G L VT+P +K V + Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617 Query: 422 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452 L NS K+ + +E+ + DP C+ Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648 >gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b [Homo sapiens] Length = 1524 Score = 31.2 bits (69), Expect = 2.4 Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 10/146 (6%) Query: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEV-TKLI 329 CD++KE+P T V ++ + AL ++E + + D+ E + + EV + + Sbjct: 404 CDDLKELPEPTPVKTRLPPEIFGDALMVLEFL--NAFGELFDLQDEFPDGVTLEVLEEAL 461 Query: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEV-------VDTYGSSILSILLEEVSPELVC 382 N +E + + + + ++++EE +EV DT G S+ S+ L+ + + Sbjct: 462 VGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKGCSLKSLDLDSCTLSEIL 521 Query: 383 SMLHLCSGTRLPALTVHVTQPKDGGF 408 + L SG + + K GGF Sbjct: 522 RLHILASGADVTSANAKYRYQKRGGF 547 >gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III isoform 2 [Homo sapiens] Length = 2098 Score = 30.8 bits (68), Expect = 3.2 Identities = 19/61 (31%), Positives = 30/61 (49%) Query: 415 LVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSF 474 L+G D +++ ST + I A L G S+ P P+ D+ YE + I V +PS Sbjct: 1610 LLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSS 1669 Query: 475 V 475 + Sbjct: 1670 I 1670 >gi|162287219 prune homolog 2 [Homo sapiens] Length = 3088 Score = 30.4 bits (67), Expect = 4.1 Identities = 36/175 (20%), Positives = 76/175 (43%), Gaps = 33/175 (18%) Query: 207 DIQTAVRT------NSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQ 260 +I+ A+ T N F + +K D+ G + + +Y+S+ + Q+ ++ + Sbjct: 239 EIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSE 298 Query: 261 PKEICALVGFCDEVKEM--PMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVC 318 E+C+ + C E++E P L P ++ + + E P+ V C+ Sbjct: 299 NMELCSQI--CCELEECQNPCLELEPFDCGCDEIL--------VYQQEDPS---VTCDQV 345 Query: 319 EFLVKEV-----TKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSI 368 +VKEV +++ N++T + + + P LS+ +++ YGS I Sbjct: 346 VLVVKEVINRRCPEMVSNSRT-----SSTEAVAGSAP--LSQGSSGIMELYGSDI 393 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 30.4 bits (67), Expect = 4.1 Identities = 46/239 (19%), Positives = 99/239 (41%), Gaps = 11/239 (4%) Query: 140 SLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNG-DVC 198 SL+ + ELN Q K+ +LD+ A LLL + ++ N D Sbjct: 618 SLETSVNELNSQLNESKEKVSQLDI-----QIKAKTELLLSAEAAKTAQRADLQNHLDTA 672 Query: 199 QDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMH 258 Q+ +Q + T V A ++ +E C +L + + + Y+S + + Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTE---ELE 729 Query: 259 MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNV-IPALELVEPIK-KHEVPAKSDVYCE 316 Q K++ A KE +Q L + + ++ + A EL + ++ + E+ + + + + Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQ 789 Query: 317 VCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEE 375 ++ + + + + EK+IL + S+ K EE + T + + + +E+ Sbjct: 790 KKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEK 848 >gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] Length = 529 Score = 30.4 bits (67), Expect = 4.1 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 324 EVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILL-EEVSPELVC 382 E+ K+I +N T + L + LSE E V+ + I + EVS E +C Sbjct: 193 ELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDIC 252 Query: 383 SMLHLCS 389 ++LHLC+ Sbjct: 253 NILHLCT 259 >gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] Length = 1153 Score = 30.0 bits (66), Expect = 5.4 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 11/94 (11%) Query: 380 LVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKG 439 L+ + L LC G L Q GF + +L G + QEI+AA ++G Sbjct: 6 LLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQG----SRVVVGAPQEIVAANQRG 61 Query: 440 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPS 473 + QCD EP+ +++ VE ++ S Sbjct: 62 SLY-------QCDYSTGSCEPIRLQVPVEAVNMS 88 >gi|7108344 granulysin isoform NKG5 [Homo sapiens] Length = 145 Score = 30.0 bits (66), Expect = 5.4 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Query: 318 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 377 C +V+++ K++D T++ + +A ++C + C+ + Y S + L+ + Sbjct: 69 CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127 Query: 378 PELVCSMLHLC 388 + +C L LC Sbjct: 128 AQQICEDLRLC 138 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,580,614 Number of Sequences: 37866 Number of extensions: 1000987 Number of successful extensions: 2785 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 2694 Number of HSP's gapped (non-prelim): 67 length of query: 524 length of database: 18,247,518 effective HSP length: 107 effective length of query: 417 effective length of database: 14,195,856 effective search space: 5919671952 effective search space used: 5919671952 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.