BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|11345450 secretin preproprotein [Homo sapiens] (121 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|11345450 secretin preproprotein [Homo sapiens] 248 8e-67 gi|153266792 adenylate cyclase activating polypeptide precursor ... 47 4e-06 gi|153266795 adenylate cyclase activating polypeptide precursor ... 47 4e-06 gi|37588853 vasoactive intestinal peptide isoform 2 preproprotei... 35 0.018 gi|4507897 vasoactive intestinal peptide isoform 1 preproprotein... 33 0.039 gi|4503945 glucagon preproprotein [Homo sapiens] 32 0.11 gi|11034841 growth hormone releasing hormone preproprotein [Homo... 31 0.25 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 30 0.33 gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 30 0.43 gi|31317307 proprotein convertase subtilisin/kexin type 9 prepro... 30 0.57 gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 30 0.57 gi|134244285 Notch homolog 3 [Homo sapiens] 29 0.74 gi|239754289 PREDICTED: hypothetical protein [Homo sapiens] 29 0.97 gi|239748826 PREDICTED: hypothetical protein XP_002346831 [Homo ... 29 0.97 gi|239742857 PREDICTED: hypothetical protein XP_002342664 [Homo ... 29 0.97 gi|239740873 PREDICTED: hypothetical protein XP_002344073 [Homo ... 29 0.97 gi|239740807 PREDICTED: hypothetical protein [Homo sapiens] 29 0.97 gi|239513965 PREDICTED: hypothetical protein [Homo sapiens] 29 0.97 gi|51988914 fibroblast growth factor receptor-like 1 precursor [... 29 0.97 gi|51988910 fibroblast growth factor receptor-like 1 precursor [... 29 0.97 gi|51988912 fibroblast growth factor receptor-like 1 precursor [... 29 0.97 gi|153792351 ADAM metallopeptidase with thrombospondin type 1 mo... 29 0.97 gi|8922108 cytokine-like 1 [Homo sapiens] 29 0.97 gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens] 29 0.97 gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] 28 1.3 gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 28 1.3 gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 28 1.3 gi|239740757 PREDICTED: hypothetical protein [Homo sapiens] 28 1.3 gi|239740703 PREDICTED: hypothetical protein [Homo sapiens] 28 1.3 gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 28 1.3 >gi|11345450 secretin preproprotein [Homo sapiens] Length = 121 Score = 248 bits (633), Expect = 8e-67 Identities = 121/121 (100%), Positives = 121/121 (100%) Query: 1 MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQ 60 MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQ Sbjct: 1 MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQ 60 Query: 61 DAENSMAWTRLSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRP 120 DAENSMAWTRLSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRP Sbjct: 61 DAENSMAWTRLSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRP 120 Query: 121 R 121 R Sbjct: 121 R 121 >gi|153266792 adenylate cyclase activating polypeptide precursor [Homo sapiens] Length = 176 Score = 46.6 bits (109), Expect = 4e-06 Identities = 22/52 (42%), Positives = 32/52 (61%) Query: 13 LGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAEN 64 LGG A A P ++RHSDG FT SR R+ +++ L ++GKR +Q +N Sbjct: 117 LGGGAGDDAEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKN 168 >gi|153266795 adenylate cyclase activating polypeptide precursor [Homo sapiens] Length = 176 Score = 46.6 bits (109), Expect = 4e-06 Identities = 22/52 (42%), Positives = 32/52 (61%) Query: 13 LGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAEN 64 LGG A A P ++RHSDG FT SR R+ +++ L ++GKR +Q +N Sbjct: 117 LGGGAGDDAEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKN 168 >gi|37588853 vasoactive intestinal peptide isoform 2 preproprotein [Homo sapiens] Length = 169 Score = 34.7 bits (78), Expect = 0.018 Identities = 18/49 (36%), Positives = 28/49 (57%) Query: 24 RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAWTRLS 72 R RH+DG FTS+ S+L ++ L+ L+GKR +E+ + R S Sbjct: 77 RNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSNISEDPVPVKRHS 125 Score = 31.6 bits (70), Expect = 0.15 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 22 PPRARRHSDGTFTSELSRLREGARLQRLLQGLV-GKRSEQ 60 P +RHSD FT +RLR+ +++ L ++ GKRS + Sbjct: 118 PVPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSE 157 >gi|4507897 vasoactive intestinal peptide isoform 1 preproprotein [Homo sapiens] Length = 170 Score = 33.5 bits (75), Expect = 0.039 Identities = 15/34 (44%), Positives = 22/34 (64%) Query: 24 RARRHSDGTFTSELSRLREGARLQRLLQGLVGKR 57 R RH+DG FTS+ S+L ++ L+ L+GKR Sbjct: 77 RNARHADGVFTSDFSKLLGQLSAKKYLESLMGKR 110 Score = 31.6 bits (70), Expect = 0.15 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 22 PPRARRHSDGTFTSELSRLREGARLQRLLQGLV-GKRSEQ 60 P +RHSD FT +RLR+ +++ L ++ GKRS + Sbjct: 119 PVPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSE 158 >gi|4503945 glucagon preproprotein [Homo sapiens] Length = 180 Score = 32.0 bits (71), Expect = 0.11 Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 27 RHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMA 67 RH++GTFTS++S EG + + LV R +D +A Sbjct: 97 RHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVA 137 Score = 30.8 bits (68), Expect = 0.25 Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 26 RRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQD 61 +RHS GTFTS+ S+ + R Q +Q L+ + ++ Sbjct: 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRN 86 >gi|11034841 growth hormone releasing hormone preproprotein [Homo sapiens] Length = 108 Score = 30.8 bits (68), Expect = 0.25 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 8 LLLLLLGGSAARPAPP---RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAEN 64 ++L L S P PP R RR++D FT+ ++ ++LLQ ++ ++ + + Sbjct: 9 VILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQE 68 Query: 65 SMAWTRL 71 A RL Sbjct: 69 RGARARL 75 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 30.4 bits (67), Expect = 0.33 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 13/92 (14%) Query: 42 EGARLQRLLQGLVGKRSEQDAENSM---AWTRLSAGLLCPSGSNMPILQAWMP------L 92 EG+ +R++ G + E++ EN + + TR + P + W+P L Sbjct: 280 EGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHL 339 Query: 93 DGTWSPW--LPPGPMVSEPAGA--AAEGTLRP 120 GT P LPPG + + PA + G +RP Sbjct: 340 PGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRP 371 >gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] Length = 2382 Score = 30.0 bits (66), Expect = 0.43 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 10/118 (8%) Query: 13 LGGSAARPAPPRARRHSDGTFTSELSRLREG-ARLQRLLQGLVGKRSEQDAENSMAWTRL 71 + AA+ PP GTFT +L +L + AR L G G + + E + Sbjct: 2226 VNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKF 2285 Query: 72 SA-GLLCPS-----GSNMPILQAWMPLDGTWSPWLPPGPMVSEPA---GAAAEGTLRP 120 SA G LC S G + PI A G ++ + P PA GA GT P Sbjct: 2286 SAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGGP 2343 >gi|31317307 proprotein convertase subtilisin/kexin type 9 preproprotein [Homo sapiens] Length = 692 Score = 29.6 bits (65), Expect = 0.57 Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 3 PRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLR 41 P PLLLLLLLL G PA RA+ DG + + LR Sbjct: 12 PLPLLLLLLLLLG----PAGARAQEDEDGDYEELVLALR 46 >gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] Length = 4646 Score = 29.6 bits (65), Expect = 0.57 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 78 PSGSNMPILQAWMPLDGTWSPWLPPGPMV 106 P+ N+PI+ + + G WSPW P + Sbjct: 2527 PTAPNIPIIDYEVSISGEWSPWQAKVPQI 2555 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 29.3 bits (64), Expect = 0.74 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 2/83 (2%) Query: 34 TSELSRLREGARLQRLLQGLVGKRSEQDAENSMAWTRLSAGLLCPSGSNMPILQAWMPLD 93 T L RL +RL Q +V + S LLCP G+ +P L+A Sbjct: 2001 TDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPGLKA--AQS 2058 Query: 94 GTWSPWLPPGPMVSEPAGAAAEG 116 G+ PPG P G G Sbjct: 2059 GSKKSRRPPGKAGLGPQGPRGRG 2081 >gi|239754289 PREDICTED: hypothetical protein [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|239748826 PREDICTED: hypothetical protein XP_002346831 [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|239742857 PREDICTED: hypothetical protein XP_002342664 [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|239740873 PREDICTED: hypothetical protein XP_002344073 [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|239740807 PREDICTED: hypothetical protein [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|239513965 PREDICTED: hypothetical protein [Homo sapiens] Length = 178 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 12/66 (18%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAW 68 S+A PAPP +RR DGT+T SR R+G L+ GKR ++ S+ Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG-----LVPRSRGKRLQKICRFSLLV 158 Query: 69 TRLSAG 74 R G Sbjct: 159 LRTHLG 164 >gi|51988914 fibroblast growth factor receptor-like 1 precursor [Homo sapiens] Length = 504 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 9/58 (15%) Query: 1 MAPRPLLLLL---LLLGG---SAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQG 52 M P PLLLLL LLLG +AA PP+ +D +++RL RLQ ++G Sbjct: 1 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKM---ADKVVPRQVARLGRTVRLQCPVEG 55 >gi|51988910 fibroblast growth factor receptor-like 1 precursor [Homo sapiens] Length = 504 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 9/58 (15%) Query: 1 MAPRPLLLLL---LLLGG---SAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQG 52 M P PLLLLL LLLG +AA PP+ +D +++RL RLQ ++G Sbjct: 1 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKM---ADKVVPRQVARLGRTVRLQCPVEG 55 >gi|51988912 fibroblast growth factor receptor-like 1 precursor [Homo sapiens] Length = 504 Score = 28.9 bits (63), Expect = 0.97 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 9/58 (15%) Query: 1 MAPRPLLLLL---LLLGG---SAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQG 52 M P PLLLLL LLLG +AA PP+ +D +++RL RLQ ++G Sbjct: 1 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKM---ADKVVPRQVARLGRTVRLQCPVEG 55 >gi|153792351 ADAM metallopeptidase with thrombospondin type 1 motif, 8 preproprotein [Homo sapiens] Length = 889 Score = 28.9 bits (63), Expect = 0.97 Identities = 17/45 (37%), Positives = 21/45 (46%), Gaps = 6/45 (13%) Query: 65 SMAW---TRLSAGLLCPSGSNMPILQAWMP---LDGTWSPWLPPG 103 S+ W T G LC GS +P + P DG W+PW P G Sbjct: 492 SLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWG 536 >gi|8922108 cytokine-like 1 [Homo sapiens] Length = 136 Score = 28.9 bits (63), Expect = 0.97 Identities = 15/22 (68%), Positives = 17/22 (77%), Gaps = 1/22 (4%) Query: 3 PRPLLLLLLLLGGS-AARPAPP 23 P PL +LLLLL G+ AARP PP Sbjct: 4 PGPLPVLLLLLAGAPAARPTPP 25 >gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens] Length = 892 Score = 28.9 bits (63), Expect = 0.97 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 15 GSAARPAPPRARRHSDGTFTSELSRLREGAR-LQRLLQGLVG 55 G A P P RARR TF R EG R L +LQG G Sbjct: 164 GPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAG 205 >gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 28.5 bits (62), Expect = 1.3 Identities = 13/27 (48%), Positives = 16/27 (59%) Query: 14 GGSAARPAPPRARRHSDGTFTSELSRL 40 GG ARP+PPRAR+ G +RL Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRL 234 >gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 28.5 bits (62), Expect = 1.3 Identities = 13/27 (48%), Positives = 16/27 (59%) Query: 14 GGSAARPAPPRARRHSDGTFTSELSRL 40 GG ARP+PPRAR+ G +RL Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRL 234 >gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 28.5 bits (62), Expect = 1.3 Identities = 13/27 (48%), Positives = 16/27 (59%) Query: 14 GGSAARPAPPRARRHSDGTFTSELSRL 40 GG ARP+PPRAR+ G +RL Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRL 234 >gi|239740757 PREDICTED: hypothetical protein [Homo sapiens] Length = 308 Score = 28.5 bits (62), Expect = 1.3 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 7/35 (20%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREG 43 S+A PAPP +RR DGT+T SR R+G Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG 138 >gi|239740703 PREDICTED: hypothetical protein [Homo sapiens] Length = 308 Score = 28.5 bits (62), Expect = 1.3 Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 7/35 (20%) Query: 16 SAARPAPP-------RARRHSDGTFTSELSRLREG 43 S+A PAPP +RR DGT+T SR R+G Sbjct: 104 SSATPAPPAGGDVTHHSRRGWDGTWTPRFSRPRDG 138 >gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] Length = 1159 Score = 28.5 bits (62), Expect = 1.3 Identities = 19/32 (59%), Positives = 21/32 (65%), Gaps = 3/32 (9%) Query: 4 RPLLLLLLLLG--GSAAR-PAPPRARRHSDGT 32 RPLLLLLLLLG G+A R P P R H+ T Sbjct: 34 RPLLLLLLLLGACGAAGRSPEPGRLGPHAQLT 65 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,780,250 Number of Sequences: 37866 Number of extensions: 261435 Number of successful extensions: 1261 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 1212 Number of HSP's gapped (non-prelim): 86 length of query: 121 length of database: 18,247,518 effective HSP length: 89 effective length of query: 32 effective length of database: 14,877,444 effective search space: 476078208 effective search space used: 476078208 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.