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Search of human proteins with 21361204
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 1265 0.0
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 1258 0.0
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 1258 0.0
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 1248 0.0
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 1168 0.0
gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens] 373 e-103
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 65 2e-10
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 65 2e-10
gi|83415184 transmembrane and tetratricopeptide repeat containin... 61 3e-09
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 55 1e-07
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 55 1e-07
gi|224809432 transmembrane and tetratricopeptide repeat containi... 49 2e-05
gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens] 48 2e-05
gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] 47 7e-05
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 45 3e-04
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 44 3e-04
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 42 0.001
gi|118766328 transmembrane and tetratricopeptide repeat containi... 42 0.002
gi|118766330 transmembrane and tetratricopeptide repeat containi... 42 0.002
gi|118402596 cell division cycle protein 23 [Homo sapiens] 40 0.005
gi|6912398 general transcription factor IIIC, polypeptide 3, 102... 40 0.005
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 40 0.007
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 39 0.011
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 39 0.015
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 39 0.019
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 39 0.019
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 39 0.019
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 39 0.019
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi... 38 0.025
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi... 38 0.025
>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
sapiens]
Length = 631
Score = 1265 bits (3274), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
Query: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIELQAELEEMAKRDAEAHPW 300
EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIELQAELEEMAKRDAEAHPW
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIELQAELEEMAKRDAEAHPW 300
Query: 301 LSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKH 360
LSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKH
Sbjct: 301 LSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKH 360
Query: 361 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRD 420
MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRD
Sbjct: 361 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRD 420
Query: 421 WLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDP 480
WLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDP
Sbjct: 421 WLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDP 480
Query: 481 DVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 540
DVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA
Sbjct: 481 DVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 540
Query: 541 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLR 600
LELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLR
Sbjct: 541 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLR 600
Query: 601 LALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
LALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 LALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 1258 bits (3255), Expect = 0.0
Identities = 631/639 (98%), Positives = 631/639 (98%), Gaps = 8/639 (1%)
Query: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
Query: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE--------LQAELEEMAK 292
EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE LQAELEEMAK
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
Query: 293 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 352
RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
Query: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412
AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
Query: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472
QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
Query: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
Query: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 592
AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
Query: 593 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 1258 bits (3255), Expect = 0.0
Identities = 631/639 (98%), Positives = 631/639 (98%), Gaps = 8/639 (1%)
Query: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
Query: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE--------LQAELEEMAK 292
EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE LQAELEEMAK
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
Query: 293 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 352
RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
Query: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412
AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
Query: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472
QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
Query: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
Query: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 592
AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
Query: 593 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
sapiens]
Length = 654
Score = 1248 bits (3229), Expect = 0.0
Identities = 631/654 (96%), Positives = 631/654 (96%), Gaps = 23/654 (3%)
Query: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEA----------- 49
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEA
Sbjct: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAVSVLEVESPGA 60
Query: 50 ----ASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR 105
ASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR
Sbjct: 61 ASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR 120
Query: 106 APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE 165
APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE
Sbjct: 121 APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE 180
Query: 166 QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG 225
QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG
Sbjct: 181 QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG 240
Query: 226 QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE--- 282
QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE
Sbjct: 241 QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDV 300
Query: 283 -----LQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR 337
LQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR
Sbjct: 301 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR 360
Query: 338 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 397
LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA
Sbjct: 361 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 420
Query: 398 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 457
LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD
Sbjct: 421 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 480
Query: 458 SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW 517
SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW
Sbjct: 481 SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW 540
Query: 518 NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 577
NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM
Sbjct: 541 NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 600
Query: 578 QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 654
>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
sapiens]
Length = 602
Score = 1168 bits (3022), Expect = 0.0
Identities = 594/639 (92%), Positives = 594/639 (92%), Gaps = 45/639 (7%)
Query: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1 MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
Query: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61 ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSE
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSE-------------------------- 214
Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE--------LQAELEEMAK 292
GTSDAWVDQFTRPVNTSALDMEFERAKSAIE LQAELEEMAK
Sbjct: 215 -----------GTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 263
Query: 293 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 352
RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 264 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 323
Query: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412
AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 324 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 383
Query: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472
QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 384 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 443
Query: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 444 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 503
Query: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 592
AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 504 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 563
Query: 593 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631
ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 564 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 602
>gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]
Length = 626
Score = 373 bits (957), Expect = e-103
Identities = 202/374 (54%), Positives = 265/374 (70%), Gaps = 23/374 (6%)
Query: 269 ALDMEFERAKSAIE--------LQAELEEMAKRDAEAHPWLSDYDD----LTSATYDKGY 316
+L+ EFERAK+A+E +QAE EEMA+R+ W+S+ + +T + +KGY
Sbjct: 261 SLEEEFERAKAAVESDTEFWDKMQAEWEEMARRN-----WISENQEAQNQVTISASEKGY 315
Query: 317 QFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQ 376
F ENP +D P FEEGL+RL+EGDLP +L EAA+ QDP EAWQ+LG TQAENE
Sbjct: 316 YFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENEN 375
Query: 377 ELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAE 436
E AI AL+RCLEL+P+N ALMALAVS+TN Q+ AC+ L++W++ P Y +LV +
Sbjct: 376 EQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKK 435
Query: 437 EGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEY 496
G GL ++R+ S + S+ VKEL+L A + IDPD+Q GLGVLF+LSGE+
Sbjct: 436 ---GSPGL--TRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEF 490
Query: 497 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGI 556
++A+D F AAL+VRP DY LWN+LGATLANG++SEEAV AY RALE+QPG+IRSRYNLGI
Sbjct: 491 NRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGI 550
Query: 557 SCINLGAHREAVEHFLEALNMQRKSRGPRG-EGGAMSENIWSTLRLALSMLGQSDAYGAA 615
SCINLGA+REAV +FL AL++QRKSR + A+S NIW+ LR+ALS++ Q + + AA
Sbjct: 551 SCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAA 610
Query: 616 DARDLSTLLTMFGL 629
+ DL LL F L
Sbjct: 611 NLGDLDVLLRAFNL 624
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 64.7 bits (156), Expect = 2e-10
Identities = 63/226 (27%), Positives = 89/226 (39%), Gaps = 17/226 (7%)
Query: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412
A++Q+P EA+ LG E Q AI R L LKPD + LA +
Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 130
Query: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472
A + L+Y P + + LG + LG L E K +L A+
Sbjct: 131 GAVQAYVSALQYNPDLYCV---------RSDLGNLLKALGRLE------EAKACYLKAIE 175
Query: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
P LG +FN GE A+ F A+++ PN + LG L +
Sbjct: 176 TQPNFAV--AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDR 233
Query: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 578
AVAAY RAL L P + NL G A++ + A+ +Q
Sbjct: 234 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 279
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 31/245 (12%)
Query: 340 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 399
+G++ A+ FE AV DP ++A+ LG E A++A R L L P++
Sbjct: 194 QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 253
Query: 400 ALAVSFTNESLQRQACETLRDWLRYTP----AYAHLVTPAEEGAGGAGLGPSKRILGSLL 455
LA + + L A +T R + P AY +L +E A
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA------------- 300
Query: 456 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNL---SGEYDKAVDCFTAALSVRPN 512
E ++ + A+RL PT D L L N+ G ++AV + AL V P
Sbjct: 301 ------EAEDCYNTALRLCPTHAD-----SLNNLANIKREQGNIEEAVRLYRKALEVFPE 349
Query: 513 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 572
+ L + L + +EA+ Y+ A+ + P + + N+G + + + A++ +
Sbjct: 350 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 409
Query: 573 EALNM 577
A+ +
Sbjct: 410 RAIQI 414
Score = 39.3 bits (90), Expect = 0.011
Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 487 GVLFNLSGEY------DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 540
GVL LS + D++ T A+ P ++ LG Q +EA+ YR A
Sbjct: 46 GVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHA 105
Query: 541 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 575
L L+P +I NL + + G AV+ ++ AL
Sbjct: 106 LRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 140
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 64.7 bits (156), Expect = 2e-10
Identities = 63/226 (27%), Positives = 89/226 (39%), Gaps = 17/226 (7%)
Query: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412
A++Q+P EA+ LG E Q AI R L LKPD + LA +
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 140
Query: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472
A + L+Y P + + LG + LG L E K +L A+
Sbjct: 141 GAVQAYVSALQYNPDLYCV---------RSDLGNLLKALGRLE------EAKACYLKAIE 185
Query: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
P LG +FN GE A+ F A+++ PN + LG L +
Sbjct: 186 TQPNFAV--AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDR 243
Query: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 578
AVAAY RAL L P + NL G A++ + A+ +Q
Sbjct: 244 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 31/245 (12%)
Query: 340 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 399
+G++ A+ FE AV DP ++A+ LG E A++A R L L P++
Sbjct: 204 QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 263
Query: 400 ALAVSFTNESLQRQACETLRDWLRYTP----AYAHLVTPAEEGAGGAGLGPSKRILGSLL 455
LA + + L A +T R + P AY +L +E A
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA------------- 310
Query: 456 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNL---SGEYDKAVDCFTAALSVRPN 512
E ++ + A+RL PT D L L N+ G ++AV + AL V P
Sbjct: 311 ------EAEDCYNTALRLCPTHAD-----SLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
Query: 513 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 572
+ L + L + +EA+ Y+ A+ + P + + N+G + + + A++ +
Sbjct: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 419
Query: 573 EALNM 577
A+ +
Sbjct: 420 RAIQI 424
Score = 39.3 bits (90), Expect = 0.011
Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 487 GVLFNLSGEY------DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 540
GVL LS + D++ T A+ P ++ LG Q +EA+ YR A
Sbjct: 56 GVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHA 115
Query: 541 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 575
L L+P +I NL + + G AV+ ++ AL
Sbjct: 116 LRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 150
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 61.2 bits (147), Expect = 3e-09
Identities = 60/245 (24%), Positives = 107/245 (43%), Gaps = 25/245 (10%)
Query: 340 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 399
+G A+ + A++ P+H A LGT + + A +R L+L P + AL
Sbjct: 388 QGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAE---AKMYYQRALQLHPQHNRALF 444
Query: 400 ALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD-S 458
L ++ + +A L+D ++Y P +A + L SLL++
Sbjct: 445 NLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSS----------------LASLLAEQE 488
Query: 459 LFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWN 518
F E +E++ ++ P S D+ GV +G +KAV + A+ + P+ ++
Sbjct: 489 RFKEAEEIYQTGIKNCPDS--SDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMV 546
Query: 519 KLGATLANGNQSEEAVAAYRRALEL-QPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 577
LG + ++ A Y+RAL++ I S LG N G + EA++ + EA +
Sbjct: 547 NLGRLYRSLGENSMAEEWYKRALQVAHKAEILS--PLGALYYNTGRYEEALQIYQEAAAL 604
Query: 578 QRKSR 582
Q R
Sbjct: 605 QPSQR 609
Score = 38.5 bits (88), Expect = 0.019
Identities = 48/221 (21%), Positives = 89/221 (40%), Gaps = 36/221 (16%)
Query: 346 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 405
AV ++ A++ P H A LG + +A +R L++ + L L +
Sbjct: 527 AVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEI-LSPLGALY 585
Query: 406 TNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFL--EV 463
N +A + ++ A L PS+R L L+ L + +
Sbjct: 586 YNTGRYEEALQIYQE--------------------AAALQPSQRELRLALAQVLAVMGQT 625
Query: 464 KELFLAAVRLDPTSIDPDVQCG-----LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWN 518
KE A ++ + + C L +++ +DKA+D AL ++P D + +
Sbjct: 626 KE----AEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVIS 681
Query: 519 KL----GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLG 555
+L G L N ++A +YR A++L P ++ N+G
Sbjct: 682 ELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMG 722
Score = 34.7 bits (78), Expect = 0.27
Identities = 22/83 (26%), Positives = 39/83 (46%)
Query: 313 DKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQA 372
DK Q + ++P F +G + ++ L A + AVQ +P +AW +G Q
Sbjct: 667 DKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQH 726
Query: 373 ENEQELLAISALRRCLELKPDNQ 395
+ + A + R L+L PD++
Sbjct: 727 IKGKYVSARAYYERALQLVPDSK 749
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 454 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 510
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 544 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 603
Query: 511 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 570
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 604 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 663
Query: 571 FLEALNMQRKS 581
F +AL++ +S
Sbjct: 664 FQKALDINPQS 674
Score = 35.8 bits (81), Expect = 0.12
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 342 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 401
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 622 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 681
Query: 402 AVSFTNESLQRQACETL 418
V +A +TL
Sbjct: 682 GVVQHALKKSEKALDTL 698
Score = 30.4 bits (67), Expect = 5.2
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 348 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 407
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 560 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 619
Query: 408 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 466
+A R+ +R P + + A G LG + + E+
Sbjct: 620 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 663
Query: 467 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 526
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 664 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 721
Query: 527 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 586
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 722 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 776
Query: 587 EGGAMSENI 595
+ E I
Sbjct: 777 ANNQIKEAI 785
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 454 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 510
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
Query: 511 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 570
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
Query: 571 FLEALNMQRKS 581
F +AL++ +S
Sbjct: 658 FQKALDINPQS 668
Score = 35.8 bits (81), Expect = 0.12
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 342 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 401
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
Query: 402 AVSFTNESLQRQACETL 418
V +A +TL
Sbjct: 676 GVVQHALKKSEKALDTL 692
Score = 30.4 bits (67), Expect = 5.2
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 348 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 407
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
Query: 408 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 466
+A R+ +R P + + A G LG + + E+
Sbjct: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
Query: 467 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 526
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
Query: 527 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 586
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
Query: 587 EGGAMSENI 595
+ E I
Sbjct: 771 ANNQIKEAI 779
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/88 (29%), Positives = 46/88 (52%)
Query: 490 FNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIR 549
F+ + +++ F +AL V N+ LWN +G L N E A+ + +A +QP I
Sbjct: 422 FHRNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIG 481
Query: 550 SRYNLGISCINLGAHREAVEHFLEALNM 577
+ N+G + NL +EA E ++ A ++
Sbjct: 482 AHMNVGRTYKNLNRTKEAEESYMMAKSL 509
Score = 39.7 bits (91), Expect = 0.009
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
Query: 470 AVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQ 529
A R+ P ++ + + N S ++A + A+S+RP+ + G L N+
Sbjct: 520 AARIAPNHLNVYINLANLIRANES-RLEEADQLYRQAISMRPDFKQAYISRGELLLKMNK 578
Query: 530 SEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSR 582
+A AY +ALEL YNL I I L EA+++F AL + K +
Sbjct: 579 PLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHK 631
Score = 36.2 bits (82), Expect = 0.094
Identities = 46/221 (20%), Positives = 91/221 (41%), Gaps = 14/221 (6%)
Query: 342 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 401
D + LF +A++ + + + W +G + A+ + ++PD+ A M +
Sbjct: 427 DWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNV 486
Query: 402 AVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRI----LGSLL-- 455
++ N + ++A E+ P + P ++ A A + P+ L +L+
Sbjct: 487 GRTYKNLNRTKEAEESYMMAKSLMPQ----IIPGKKYA--ARIAPNHLNVYINLANLIRA 540
Query: 456 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYL 515
++S E +L+ A+ + P G L + KA + + AL + N+
Sbjct: 541 NESRLEEADQLYRQAISMRPDF--KQAYISRGELLLKMNKPLKAKEAYLKALELDRNNAD 598
Query: 516 LWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGI 556
LW L + EA+ + RALEL P + + +N I
Sbjct: 599 LWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAI 639
>gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens]
Length = 519
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/90 (35%), Positives = 44/90 (48%)
Query: 486 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 545
LG F +G Y +AV FT AL + P D+ L+ Q A+A + AL L+P
Sbjct: 311 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 370
Query: 546 GYIRSRYNLGISCINLGAHREAVEHFLEAL 575
G+ R + LG + + L REA F E L
Sbjct: 371 GWPRGLFRLGKALMGLQRFREAAAVFQETL 400
>gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
Length = 843
Score = 46.6 bits (109), Expect = 7e-05
Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 312 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 371
YDK ++ R + L L+ + V FE +V+ +P + W LG
Sbjct: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
Query: 372 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 430
E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H
Sbjct: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
Query: 431 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 484
++T + G + R+L L ++V ++ + AV T DV
Sbjct: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
Query: 485 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532
GL G L L G V ND +W NG QSE+
Sbjct: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
Score = 37.4 bits (85), Expect = 0.042
Identities = 21/81 (25%), Positives = 36/81 (44%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 554
E+ + V+CF ++ + P +W LG + + A++R + L+P + NL
Sbjct: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
Query: 555 GISCINLGAHREAVEHFLEAL 575
S I L +A EAL
Sbjct: 602 STSYIRLKQKVKAFRTLQEAL 622
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 14/174 (8%)
Query: 431 LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLF 490
L+ A E AGLG + R + L + E ++L +A L + + LG++
Sbjct: 427 LMEKAIEMRAYAGLGHAARCMQDLERAKQYHE-QQLGIAE-DLKDRAAEGRASSNLGIIH 484
Query: 491 NLSGEYDKAVDCFTAALSVRP--NDYLLWNKLGATLANGNQS----EEAVAAYRRALEL- 543
+ G+YD A+ L + +DY + + N + ++AV +R+ L++
Sbjct: 485 QMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQIS 544
Query: 544 -----QPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 592
+ + NL ++ LGAH A++H+ LN+ R+ R + E A+S
Sbjct: 545 MEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALS 598
Score = 38.1 bits (87), Expect = 0.025
Identities = 22/88 (25%), Positives = 43/88 (48%)
Query: 494 GEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYN 553
G++ A+ + AL+V P + +L++ A Q ++A+ +A L P + ++ +
Sbjct: 72 GDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFR 131
Query: 554 LGISCINLGAHREAVEHFLEALNMQRKS 581
G++ LG H +A+ F L KS
Sbjct: 132 QGVALQYLGRHADALAAFASGLAQDPKS 159
Score = 30.0 bits (66), Expect = 6.7
Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 12/118 (10%)
Query: 478 IDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVR------PNDYLLWNKLGATLANGNQSE 531
++ LG + + +YDKA+ T L V P + L A +
Sbjct: 752 LEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYT 811
Query: 532 EAVAAYRRALEL-----QPGYIRSRY-NLGISCINLGAHREAVEHFLEALNMQRKSRG 583
A Y L+L P Y N+GI+ +N+ EA+ +F + L M ++ G
Sbjct: 812 MAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSG 869
Score = 29.6 bits (65), Expect = 8.8
Identities = 22/105 (20%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 477 SIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAA 536
+++ D CGLG ++ GEYD A+ L + + G N + E++
Sbjct: 994 ALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQ-GRAYGNLGLTYESLGT 1052
Query: 537 YRRALELQPGYIRSRYNLG------ISCINLGAHREAVEHFLEAL 575
+ RA+ Q ++ + +S +LG A++++ +A+
Sbjct: 1053 FERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAV 1097
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/236 (21%), Positives = 88/236 (37%), Gaps = 20/236 (8%)
Query: 346 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 405
A+ ++ A + + K E LG +Q A L L L + T +M +
Sbjct: 120 AIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHL 179
Query: 406 TNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSL-LSDSLFLEVK 464
L + A E + + ++P L+T LG L L ++ +
Sbjct: 180 LEGDLDK-AIEVYKKAVEFSPENTELLTT----------------LGLLYLQLGIYQKAF 222
Query: 465 ELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATL 524
E A+ DPT+ + G + G++D A+ + P LWN +G
Sbjct: 223 EHLGNALTYDPTNYKAILAAGS--MMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCF 280
Query: 525 ANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 580
+ A++ +RA L P + YNLG+ + + + A A+N Q K
Sbjct: 281 FGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPK 336
Score = 31.2 bits (69), Expect = 3.0
Identities = 20/92 (21%), Positives = 39/92 (42%)
Query: 488 VLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGY 547
++F L G ++++ F + P ++ +L + + A+ Y A +L
Sbjct: 75 LIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKD 134
Query: 548 IRSRYNLGISCINLGAHREAVEHFLEALNMQR 579
+NLG+ I L +A + ALN+ R
Sbjct: 135 WEISHNLGVCYIYLKQFNKAQDQLHNALNLNR 166
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/282 (23%), Positives = 101/282 (35%), Gaps = 34/282 (12%)
Query: 307 LTSATYDKGYQFEE-----ENPLRDHPQPFE----EGLRRLQEGDLPNAVLLFEAAVQQD 357
L S Y F+E E+ L +P E E L + D A F+ A+++D
Sbjct: 391 LKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKD 450
Query: 358 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACET 417
+ E LG T +E LK M + + +
Sbjct: 451 TEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDK 510
Query: 418 LRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTS 477
R Y A+ T AE GA L S+ LE E+ LA + T+
Sbjct: 511 NRARGCYRKAFELDDTDAESGAAAVDL-------------SVELEDMEMALAIL----TT 553
Query: 478 IDPDVQCGL--------GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQ 529
+ G G+ + +G++ +AV AAL P D+ W LG +
Sbjct: 554 VTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGG 613
Query: 530 SEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHF 571
A+ ++ +A EL P I S + + LG ++EAV +
Sbjct: 614 YTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQY 655
Score = 36.2 bits (82), Expect = 0.094
Identities = 18/52 (34%), Positives = 28/52 (53%)
Query: 351 EAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALA 402
+ ++Q+ + AW ++G AE EQ A SA ++ EL+PD A LA
Sbjct: 30 KTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/51 (33%), Positives = 27/51 (52%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 545
EY +A+ L N+Y W +G A Q ++A +AY++A EL+P
Sbjct: 21 EYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEP 71
Score = 35.0 bits (79), Expect = 0.21
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 5/107 (4%)
Query: 442 AGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVD 501
A G + L LL SL K AVRLD + G+ ++ G Y A
Sbjct: 794 AETGSNMNDLKELLEKSLHCLKK-----AVRLDSNNHLYWNALGVVACYSGIGNYALAQH 848
Query: 502 CFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYI 548
CF ++ + + W LG E+A A++ A L P Y+
Sbjct: 849 CFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYL 895
Score = 32.7 bits (73), Expect = 1.0
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 469 AAVRLDPTSIDPDVQC--GLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 526
AA+R DP D C LG + G Y A+ FT A + P K+ A
Sbjct: 589 AALRADPK----DFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQI 644
Query: 527 GNQSEEAVAAYRRALELQPGYIRSRYNLG 555
+ +EAVA Y+ ++ + Y+ + LG
Sbjct: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLG 673
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/270 (22%), Positives = 103/270 (38%), Gaps = 28/270 (10%)
Query: 338 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 397
L+ G+ + LF +A+ P + + +G A+ + AI R + L P A
Sbjct: 459 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 518
Query: 398 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 457
+ L + ++A E L ++ P +A A LG ++ +
Sbjct: 519 MNNLGNILKERNELQEAEELLSLAVQIQPDFA---------AAWMNLG--------IVQN 561
Query: 458 SLFLEVKELFLAAVRLDPTSID-----PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN 512
SL + F AA + T+I PD LG L+ + A++ + A ++P
Sbjct: 562 SL-----KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPE 616
Query: 513 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 572
L WN + L N +A A R ALEL P ++L ++E+ FL
Sbjct: 617 HSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 676
Query: 573 EALNMQRKSRGPRGEGGAMSENIWSTLRLA 602
+A+ + G + W L LA
Sbjct: 677 KAIKANPNAASYHGNLAVLYHR-WGHLDLA 705
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 31/269 (11%)
Query: 334 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPD 393
G +G+ A+ + AV+ +PK++ A LG E + A L ++++PD
Sbjct: 489 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 548
Query: 394 NQTALMALAVSFTNESLQR-QACE-----TLRDWLRYTPAYAHLVTPAEEGAGGAGLGPS 447
A M L + SL+R +A E ++ +Y Y +
Sbjct: 549 FAAAWMNLGI--VQNSLKRFEAAEQSYRTAIKHRRKYPDCYYN----------------- 589
Query: 448 KRILGSLLSD-SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAA 506
LG L +D + ++ + A L P + +L + +G +A A
Sbjct: 590 ---LGRLYADLNRHVDALNAWRNATVLKPE--HSLAWNNMIILLDNTGNLAQAEAVGREA 644
Query: 507 LSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHRE 566
L + PND+ L L L + +E+ A + +A++ P NL + G
Sbjct: 645 LELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDL 704
Query: 567 AVEHFLEALNMQRKSRGPRGEGGAMSENI 595
A +H+ +L + + G + G + +
Sbjct: 705 AKKHYEISLQLDPTASGTKENYGLLRRKL 733
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/270 (22%), Positives = 103/270 (38%), Gaps = 28/270 (10%)
Query: 338 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 397
L+ G+ + LF +A+ P + + +G A+ + AI R + L P A
Sbjct: 478 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 537
Query: 398 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 457
+ L + ++A E L ++ P +A A LG ++ +
Sbjct: 538 MNNLGNILKERNELQEAEELLSLAVQIQPDFA---------AAWMNLG--------IVQN 580
Query: 458 SLFLEVKELFLAAVRLDPTSID-----PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN 512
SL + F AA + T+I PD LG L+ + A++ + A ++P
Sbjct: 581 SL-----KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPE 635
Query: 513 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 572
L WN + L N +A A R ALEL P ++L ++E+ FL
Sbjct: 636 HSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 695
Query: 573 EALNMQRKSRGPRGEGGAMSENIWSTLRLA 602
+A+ + G + W L LA
Sbjct: 696 KAIKANPNAASYHGNLAVLYHR-WGHLDLA 724
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 31/269 (11%)
Query: 334 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPD 393
G +G+ A+ + AV+ +PK++ A LG E + A L ++++PD
Sbjct: 508 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 567
Query: 394 NQTALMALAVSFTNESLQR-QACE-----TLRDWLRYTPAYAHLVTPAEEGAGGAGLGPS 447
A M L + SL+R +A E ++ +Y Y +
Sbjct: 568 FAAAWMNLGI--VQNSLKRFEAAEQSYRTAIKHRRKYPDCYYN----------------- 608
Query: 448 KRILGSLLSD-SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAA 506
LG L +D + ++ + A L P + +L + +G +A A
Sbjct: 609 ---LGRLYADLNRHVDALNAWRNATVLKPE--HSLAWNNMIILLDNTGNLAQAEAVGREA 663
Query: 507 LSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHRE 566
L + PND+ L L L + +E+ A + +A++ P NL + G
Sbjct: 664 LELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDL 723
Query: 567 AVEHFLEALNMQRKSRGPRGEGGAMSENI 595
A +H+ +L + + G + G + +
Sbjct: 724 AKKHYEISLQLDPTASGTKENYGLLRRKL 752
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 40.4 bits (93), Expect = 0.005
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 484 CGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 543
C +G ++L +++KA F AL + P W +G + A+ AYR A+E+
Sbjct: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394
Query: 544 QPGYIRSRYNLG 555
R+ Y LG
Sbjct: 395 NKRDYRAWYGLG 406
Score = 32.7 bits (73), Expect = 1.0
Identities = 16/60 (26%), Positives = 30/60 (50%)
Query: 346 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 405
A L F+ A++ +P+++ AW +G E + AI A R +E+ + A L ++
Sbjct: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTY 409
>gi|6912398 general transcription factor IIIC, polypeptide 3, 102kDa
[Homo sapiens]
Length = 886
Score = 40.4 bits (93), Expect = 0.005
Identities = 22/100 (22%), Positives = 47/100 (47%)
Query: 486 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 545
L +++ G+ +K++ A + P+D W +L + ++A+ Y +AL+ +P
Sbjct: 189 LAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEP 248
Query: 546 GYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPR 585
+R + +G H+ A++ + LN+ S G R
Sbjct: 249 TNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGER 288
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 40.0 bits (92), Expect = 0.007
Identities = 24/78 (30%), Positives = 39/78 (50%)
Query: 484 CGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 543
C ++ G Y AV A+ + P + ++G L++ N+ EAVA Y++ALEL
Sbjct: 129 CNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALEL 188
Query: 544 QPGYIRSRYNLGISCINL 561
P + NL I+ + L
Sbjct: 189 DPDNETYKSNLKIAELKL 206
Score = 34.3 bits (77), Expect = 0.36
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 496 YDKAVDCFTAALSVRP-NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 554
++ AV + A+ + P N N+ A GN + AV RA+ + P Y ++ +
Sbjct: 107 FEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAG-AVQDCERAICIDPAYSKAYGRM 165
Query: 555 GISCINLGAHREAVEHFLEALNM 577
G++ +L H EAV ++ +AL +
Sbjct: 166 GLALSSLNKHVEAVAYYKKALEL 188
Score = 33.5 bits (75), Expect = 0.61
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 341 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQT 396
G+ AV E A+ DP + +A+ +G + + + A++ ++ LEL PDN+T
Sbjct: 139 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNET 194
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 39.3 bits (90), Expect = 0.011
Identities = 20/82 (24%), Positives = 41/82 (50%)
Query: 496 YDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLG 555
Y AVDC+T A+ + PN+ + + A + +A+ +A+ + Y ++ +G
Sbjct: 101 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMG 160
Query: 556 ISCINLGAHREAVEHFLEALNM 577
++ L EAV + +AL++
Sbjct: 161 LALTALNKFEEAVTSYQKALDL 182
Score = 37.0 bits (84), Expect = 0.055
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 465 ELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATL 524
+ + A+ LDP + C + G Y A+ A+++ + ++G L
Sbjct: 106 DCYTQAIELDPNNAV--YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLAL 163
Query: 525 ANGNQSEEAVAAYRRALELQPGYIRSRYNLGIS 557
N+ EEAV +Y++AL+L P + NL I+
Sbjct: 164 TALNKFEEAVTSYQKALDLDPENDSYKSNLKIA 196
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 38.9 bits (89), Expect = 0.015
Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 554
+Y +A C+ A++ P + + Q E+A+A RRALEL +++ + L
Sbjct: 41 KYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFL 100
Query: 555 GISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLA 602
G + + ++ EA+ + A ++ ++ R G ++I S LR+A
Sbjct: 101 GQCQLEMESYDEAIANLQRAYSLAKEQRLNFG------DDIPSALRIA 142
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 38.5 bits (88), Expect = 0.019
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 495 EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 551
E+++AV+ FT AL + P + Y+ + +++A + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 552 YNLGISCINLGAHREAVEHFLEALNMQRKS 581
+ G + G ++A HF A++ K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408
Score = 35.0 bits (79), Expect = 0.21
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 544
+Y+ A + ALS++PND L++N EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 30.0 bits (66), Expect = 6.7
Identities = 21/89 (23%), Positives = 39/89 (43%)
Query: 341 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 400
G NA+ ++ A+ +PK+ A+ G + Q A + L+ P+N+ LM
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515
Query: 401 LAVSFTNESLQRQACETLRDWLRYTPAYA 429
A++ T +A E + + P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 38.5 bits (88), Expect = 0.019
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 495 EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 551
E+++AV+ FT AL + P + Y+ + +++A + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 552 YNLGISCINLGAHREAVEHFLEALNMQRKS 581
+ G + G ++A HF A++ K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408
Score = 35.0 bits (79), Expect = 0.21
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 544
+Y+ A + ALS++PND L++N EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 30.0 bits (66), Expect = 6.7
Identities = 21/89 (23%), Positives = 39/89 (43%)
Query: 341 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 400
G NA+ ++ A+ +PK+ A+ G + Q A + L+ P+N+ LM
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515
Query: 401 LAVSFTNESLQRQACETLRDWLRYTPAYA 429
A++ T +A E + + P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 38.5 bits (88), Expect = 0.019
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 495 EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 551
E+++AV+ FT AL + P + Y+ + +++A + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 552 YNLGISCINLGAHREAVEHFLEALNMQRKS 581
+ G + G ++A HF A++ K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408
Score = 35.0 bits (79), Expect = 0.21
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 544
+Y+ A + ALS++PND L++N EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 30.0 bits (66), Expect = 6.7
Identities = 21/89 (23%), Positives = 39/89 (43%)
Query: 341 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 400
G NA+ ++ A+ +PK+ A+ G + Q A + L+ P+N+ LM
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515
Query: 401 LAVSFTNESLQRQACETLRDWLRYTPAYA 429
A++ T +A E + + P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo
sapiens]
Length = 1756
Score = 38.5 bits (88), Expect = 0.019
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 441 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 496
G+ P K++ G + L+ E KE LA L DP LG+L+ L
Sbjct: 17 GSAPSPGKKLRGFYFA-KLYYEAKEYDLAKKYVCTYLSVQERDPRAHRFLGLLYELEENT 75
Query: 497 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 546
+KAV+C+ +L + P L K+ L N + A Y RA +L PG
Sbjct: 76 EKAVECYRRSLELNPPQKDLVLKIAELLCK-NDVTDGRAKYWVERAAKLFPG 126
>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo
sapiens]
Length = 1758
Score = 38.1 bits (87), Expect = 0.025
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 441 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 496
G+ P K+ L+ E KE LA ++ +DP LG+L+ L
Sbjct: 17 GSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEENT 76
Query: 497 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 546
+KAV+C+ ++ + P L K+ L N + A Y RA +L PG
Sbjct: 77 EKAVECYRRSVELNPTQKDLVLKIAELLCK-NDVTDGRAEYWVERAAKLFPG 127
>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo
sapiens]
Length = 1758
Score = 38.1 bits (87), Expect = 0.025
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 441 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 496
G+ P K+ L+ E KE LA ++ +DP LG+L+ L
Sbjct: 17 GSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEENT 76
Query: 497 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 546
+KAV+C+ ++ + P L K+ L N + A Y RA +L PG
Sbjct: 77 EKAVECYRRSVELNPTQKDLVLKIAELLCK-NDVTDGRAKYWVERAAKLFPG 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,862,314
Number of Sequences: 37866
Number of extensions: 1159688
Number of successful extensions: 3750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 3403
Number of HSP's gapped (non-prelim): 327
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.