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Search of human proteins with 213511508
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|213511508 B-cell receptor-associated protein 31 isoform a
[Homo sapiens]
(313 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|213511508 B-cell receptor-associated protein 31 isoform a [Ho... 603 e-173
gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom... 471 e-133
gi|213511012 B-cell receptor-associated protein 31 isoform b [Ho... 471 e-133
gi|56549093 B-cell receptor-associated protein BAP29 isoform a [... 224 6e-59
gi|56549091 B-cell receptor-associated protein BAP29 isoform b [... 224 6e-59
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 48 1e-05
gi|212276088 leucine rich repeat (in FLII) interacting protein 1... 44 1e-04
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 44 1e-04
gi|55770834 centromere protein F [Homo sapiens] 42 7e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 42 0.001
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 41 0.001
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 40 0.003
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 40 0.003
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 40 0.003
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 40 0.003
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 40 0.003
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.003
gi|38044112 restin isoform b [Homo sapiens] 40 0.003
gi|4506751 restin isoform a [Homo sapiens] 40 0.003
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.005
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 39 0.005
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 39 0.005
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 39 0.005
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 39 0.005
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 39 0.005
gi|156104908 myosin heavy chain 6 [Homo sapiens] 39 0.005
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 39 0.005
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 39 0.006
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.006
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 39 0.006
>gi|213511508 B-cell receptor-associated protein 31 isoform a [Homo
sapiens]
Length = 313
Score = 603 bits (1554), Expect = e-173
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MGAEASSSWCPGTALPEERLSVKRASEISGFLGQGSSGEAALDVLTHVLEGAGNKLTSSC 60
MGAEASSSWCPGTALPEERLSVKRASEISGFLGQGSSGEAALDVLTHVLEGAGNKLTSSC
Sbjct: 1 MGAEASSSWCPGTALPEERLSVKRASEISGFLGQGSSGEAALDVLTHVLEGAGNKLTSSC 60
Query: 61 GKPSSNRMSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFV 120
GKPSSNRMSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFV
Sbjct: 61 GKPSSNRMSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFV 120
Query: 121 VLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLS 180
VLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLS
Sbjct: 121 VLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLS 180
Query: 181 FLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNA 240
FLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNA
Sbjct: 181 FLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNA 240
Query: 241 EVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
EVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL
Sbjct: 241 EVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
Query: 301 QAAVDGPMDKKEE 313
QAAVDGPMDKKEE
Sbjct: 301 QAAVDGPMDKKEE 313
>gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo
sapiens]
Length = 246
Score = 471 bits (1213), Expect = e-133
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127
MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV
Sbjct: 1 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
Query: 128 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 187
LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV
Sbjct: 61 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
Query: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247
TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE
Sbjct: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
Query: 248 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 307
NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP
Sbjct: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240
Query: 308 MDKKEE 313
MDKKEE
Sbjct: 241 MDKKEE 246
>gi|213511012 B-cell receptor-associated protein 31 isoform b [Homo
sapiens]
Length = 246
Score = 471 bits (1213), Expect = e-133
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127
MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV
Sbjct: 1 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
Query: 128 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 187
LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV
Sbjct: 61 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
Query: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247
TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE
Sbjct: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
Query: 248 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 307
NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP
Sbjct: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240
Query: 308 MDKKEE 313
MDKKEE
Sbjct: 241 MDKKEE 246
>gi|56549093 B-cell receptor-associated protein BAP29 isoform a
[Homo sapiens]
Length = 348
Score = 224 bits (572), Expect = 6e-59
Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)
Query: 68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127
M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF + + ++ N F+ +I++L+
Sbjct: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
Query: 128 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 186
+L +DAVRE+RKY V T + + + P A EH MKLFR+QRNLYI+GFSL +LRRL
Sbjct: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
Query: 187 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 246
VTLI+Q A L++ K QAE+ ++AAKK+MEEN++LK+ G + E LE
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
Query: 247 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301
EN+ L D +KLK EL T L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
>gi|56549091 B-cell receptor-associated protein BAP29 isoform b
[Homo sapiens]
Length = 241
Score = 224 bits (572), Expect = 6e-59
Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)
Query: 68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127
M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF + + ++ N F+ +I++L+
Sbjct: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
Query: 128 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 186
+L +DAVRE+RKY V T + + + P A EH MKLFR+QRNLYI+GFSL +LRRL
Sbjct: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
Query: 187 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 246
VTLI+Q A L++ K QAE+ ++AAKK+MEEN++LK+ G + E LE
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
Query: 247 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301
EN+ L D +KLK EL T L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 18/127 (14%)
Query: 197 LASNEAFKKQAESASEAAKKYMEE-NDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKAD- 254
L S EA KK+ E + A++ MEE ++++K A K+ ++LEEEN L+A+
Sbjct: 1650 LRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI------LELEEENDRLRAEV 1703
Query: 255 ----------LQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 304
++ L AS K++LE+ + + + K+ + L E D L EE L+ +
Sbjct: 1704 HPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQI 1763
Query: 305 DGPMDKK 311
+G + K+
Sbjct: 1764 EGNVSKQ 1770
Score = 47.8 bits (112), Expect = 1e-05
Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 28/182 (15%)
Query: 146 KVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKK 205
++ +N A+EH R + +A F +LL S+ A +LA N KK
Sbjct: 2057 EITKENLAQAVEH------RKKAQAELASFKVLLD-------DTQSEAARVLADNLKLKK 2103
Query: 206 QAESASEAAKKYMEENDQ-------------LKKGAAVDGGKLDVGNAE-VKLEEENRSL 251
+ +S E+ K M++ D+ LK+ + KLD E V LEE +
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQE-KLDALRREKVHLEETIGEI 2162
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 311
+ L K E+ ++ L+ Q+ A K L + DR+++E K + + K
Sbjct: 2163 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSK 2222
Query: 312 EE 313
EE
Sbjct: 2223 EE 2224
Score = 33.5 bits (75), Expect = 0.25
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 179 LSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG 238
+S + L +SQ+ + + + + E ++ +EE DQ V +
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQ-----QVTEISFSMT 911
Query: 239 NAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 293
V+L EE SL +++ LK++L + E + QV + S GL + YD +
Sbjct: 912 EKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEM 966
Score = 32.3 bits (72), Expect = 0.56
Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 204 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDEL 262
K A+ E K+ +E QL+K K+ VK LE + DL+ K+ L
Sbjct: 2004 KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENL 2063
Query: 263 ASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL-------QAAVDGPMDKKEE 313
A + +KA+ ++ + + + E R+L ++ KL + +V M +K+E
Sbjct: 2064 AQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE 2121
Score = 31.2 bits (69), Expect = 1.2
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 15/103 (14%)
Query: 212 EAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLE 270
EAAKK E D+LKK E+K L + ++ + + ++ +A + L
Sbjct: 2668 EAAKKVGEIEDKLKK--------------ELKHLHHDAGIMRNETETAEERVAELARDLV 2713
Query: 271 KAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
+ E ++L + K+++GLT + + LQ + D ++ +E
Sbjct: 2714 EMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Score = 29.6 bits (65), Expect = 3.6
Identities = 17/60 (28%), Positives = 29/60 (48%)
Query: 246 EENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
+EN+SL+ +L + + + L E+QV A K+ + + L EE KL +D
Sbjct: 1497 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD 1556
Score = 29.3 bits (64), Expect = 4.7
Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 3/53 (5%)
Query: 244 LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
LE+E L+ +KL++ L S K L+KA+ + +R++ + +Y+RL E+
Sbjct: 1169 LEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1218
Score = 28.5 bits (62), Expect = 8.0
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Query: 201 EAFKKQAESASEAAKKYMEENDQL----KKGAAVDGGKLDVGNAEVKLEEENRSLKADLQ 256
E FKK A++ S A EE DQL K+ + V + V E+ L E R + D +
Sbjct: 726 EEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYE 785
>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
isoform 2 [Homo sapiens]
Length = 394
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 185 RLVTLISQQATLLASNEAFKKQAESASEAAK--KYMEENDQLKKGAAVDGGKLDVGNAEV 242
RL L+ ++ LL + K Q E + K E+D L+ G + V + +
Sbjct: 243 RLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGT-----DMHVMDLQR 297
Query: 243 KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 302
+ LK L K + E+ + +Q + + E+QV + +E K D L E KLQ
Sbjct: 298 DANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQR 357
Query: 303 AVDGPMDKKEE 313
+ +DK EE
Sbjct: 358 ELRSALDKTEE 368
Score = 29.3 bits (64), Expect = 4.7
Identities = 33/158 (20%), Positives = 62/158 (39%), Gaps = 40/158 (25%)
Query: 193 QATLLASNEAFKKQAESASEAAKKYMEENDQLKKG------AAVDGGKLDVGNAEVKLEE 246
+A + E ++Q E K + E+ + G A++ G G+ + +
Sbjct: 36 EAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI 95
Query: 247 ENRSLKADLQKLKDELASTKQKLEKA----------------------------ENQVLA 278
+ +A ++++KD LA ++K +KA E Q+
Sbjct: 96 DT---EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAE 152
Query: 279 MRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDKKEE 313
R+Q E KE++R H+ LQ A V + ++EE
Sbjct: 153 SRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 190
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 185 RLVTLISQQATLLASNEAFKKQAESASEAAK--KYMEENDQLKKGAAVDGGKLDVGNAEV 242
RL L+ ++ LL + K Q E + K E+D L+ G + V + +
Sbjct: 489 RLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGT-----DMHVMDLQR 543
Query: 243 KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 302
+ LK L K + E+ + +Q + + E+QV + +E K D L E KLQ
Sbjct: 544 DANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQR 603
Query: 303 AVDGPMDKKEE 313
+ +DK EE
Sbjct: 604 ELRSALDKTEE 614
Score = 30.0 bits (66), Expect = 2.8
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 15/104 (14%)
Query: 216 KYMEENDQLKKGAAVDGGKLD---VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKA 272
KYM+ ++K A K V NA++ E+ N + D + K L +
Sbjct: 280 KYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---------TLKDMLLEL 330
Query: 273 ENQVLAMRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDKKEE 313
E Q+ R+Q E KE++R H+ LQ A V + ++EE
Sbjct: 331 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 374
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 18/124 (14%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL--------K 252
EA +K+ +E K+ END LK K++ E+++ EEN+ L K
Sbjct: 2129 EADEKKQLHIAEKLKERERENDSLKD-------KVENLERELQMSEENQELVILDAENSK 2181
Query: 253 ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTK---EYDRLLEEHAKLQAAVDGPMD 309
A+++ LK ++ + L+ E ++ +R + E LTK E L E KL ++ ++
Sbjct: 2182 AEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLE 2241
Query: 310 KKEE 313
+KE+
Sbjct: 2242 EKEQ 2245
Score = 33.9 bits (76), Expect = 0.19
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 17/123 (13%)
Query: 197 LASNEAFKKQAESASEAAKKYMEENDQLK-----KGAAVDGGKLDVGNAEVKLEEENRSL 251
L +EA KK + K+Y E + K + KL++ + EE N SL
Sbjct: 2701 LRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSL 2760
Query: 252 KADLQKLKDELASTK-----------QKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
KA Q L +EL TK ++ E+A+ ++ + K + L +E + L +E ++L
Sbjct: 2761 KATTQIL-EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2819
Query: 301 QAA 303
QAA
Sbjct: 2820 QAA 2822
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)
Query: 204 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 263
K+Q + ++ + +++ Q + +G L N +L E SL+ QK+ EL
Sbjct: 34 KQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQ--RLMEICESLEKTKQKISHELQ 91
Query: 264 STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 303
+ ++ E Q+ + +KQ E L +E R E + Q A
Sbjct: 92 VKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/120 (17%), Positives = 52/120 (43%), Gaps = 7/120 (5%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGG-------KLDVGNAEVKLEEENRSLKA 253
+ +K+ E S + ++ + K + V+G L++ N V+LE++ + L++
Sbjct: 2515 QKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS 2574
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
L+D L + + EN++ + ++ +++ + +LQ + K E
Sbjct: 2575 KNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE 2634
Score = 28.9 bits (63), Expect = 6.2
Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 18/142 (12%)
Query: 186 LVTLISQQATLLASNEA----------FKKQAESASEAAKKYMEENDQLKKGAAVDGGKL 235
LVT Q +LLA ++ +Q SE ++ +E DQ K +A+ ++
Sbjct: 774 LVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA-DQSPKNSAILQNRV 832
Query: 236 DVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 295
D + E LE + + + +DLQK +EL K ++E+ + M + T + L+
Sbjct: 833 D--SLEFSLESQ-KQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQ 889
Query: 296 E----HAKLQAAVDGPMDKKEE 313
E H + A ++ KE+
Sbjct: 890 EDTSAHQNVVAETLSALENKEK 911
Score = 28.9 bits (63), Expect = 6.2
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 29/134 (21%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 241
L L + S++ L + K+ + + ++K E+ +L+ + + V AE
Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAE 2008
Query: 242 VK----------------------LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAM 279
VK L+E+ +SL+ D Q L+ TK +L ENQ+ +
Sbjct: 2009 VKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQ----ALSLTKCEL---ENQIAQL 2061
Query: 280 RKQSEGLTKEYDRL 293
K+ E L KE + L
Sbjct: 2062 NKEKELLVKESESL 2075
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/120 (25%), Positives = 64/120 (53%), Gaps = 5/120 (4%)
Query: 195 TLLASNEAFKKQAESASEAAKKYMEENDQLKKGAA-VDGGKLDVGNAEVKLEEENRSLKA 253
TLL E ++ AE K + + D ++ A + K++ A LE + +KA
Sbjct: 623 TLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVETEEATACLELKFNQIKA 682
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
+L K K EL TK++L+K EN+ ++ ++ E K +++ ++ +++ ++ +D+KE+
Sbjct: 683 ELAKTKGELIKTKEELKKRENESDSLIQELETSNK---KIITQNQRIKELIN-IIDQKED 738
Score = 34.3 bits (77), Expect = 0.15
Identities = 24/106 (22%), Positives = 53/106 (50%), Gaps = 15/106 (14%)
Query: 190 ISQQATLLASN-EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEEN 248
+ ++ T L +N + K + E + +E ++LK+ + +
Sbjct: 1185 LKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSAR-------------T 1231
Query: 249 RSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLL 294
++LKADLQ+ +++ A K+KL A+ Q+ ++K+ + ++ D+LL
Sbjct: 1232 QNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKE-VSVMRDEDKLL 1276
Score = 32.0 bits (71), Expect = 0.73
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 7/73 (9%)
Query: 236 DVGNAEVKLEEENRSLKADLQKLK-------DELASTKQKLEKAENQVLAMRKQSEGLTK 288
D+ E+KL+EE L +LQ +K +E + +Q+ EK + ++ A +++ L
Sbjct: 1177 DLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKA 1236
Query: 289 EYDRLLEEHAKLQ 301
+ R E++A L+
Sbjct: 1237 DLQRKEEDYADLK 1249
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 13/127 (10%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 241
LL +V L A + ++ E A A ++ +E Q + A+ + K +
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKE----- 219
Query: 242 VKLEEENRSLKADLQKLKDELAS-------TKQKLEKAENQVLAMRKQSEGLTKEYDRLL 294
KLE+E + ++AD+ + E+ + +K++L+K E Q+ + +E KE ++
Sbjct: 220 -KLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQ 278
Query: 295 EEHAKLQ 301
+AKLQ
Sbjct: 279 MRNAKLQ 285
Score = 36.6 bits (83), Expect = 0.030
Identities = 25/90 (27%), Positives = 51/90 (56%), Gaps = 8/90 (8%)
Query: 215 KKYMEENDQLKKG-AAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTK---QKLE 270
K + + D+LK+ +A + + + + ++E+E +LKA+LQKL+ + TK +K E
Sbjct: 520 KIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE 579
Query: 271 KAENQVLAMRKQSEG----LTKEYDRLLEE 296
E ++L + +++G KE D+++ E
Sbjct: 580 AEERKLLRIIAEADGERLRQKKELDQVISE 609
Score = 35.4 bits (80), Expect = 0.066
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247
TL +Q L EA KKQAE +A + + E D L K VKL E+
Sbjct: 353 TLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQ 412
Query: 248 -NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKE 289
R+L+ ++Q KDE ++ + E + Q+ LT++
Sbjct: 413 AKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQK 455
Score = 31.6 bits (70), Expect = 0.95
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 36/151 (23%)
Query: 199 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEV----KLEEENR----S 250
S E F+ + E KK + +L ++ V +A+V KL ++++ S
Sbjct: 35 SLEKFRIEYERLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIAS 94
Query: 251 LKADLQKLKDELASTKQKLEKAENQVLAMRKQ---------------------------- 282
LK +++K + S K +KA+ +LA++++
Sbjct: 95 LKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRF 154
Query: 283 SEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
E +TKE D+LL E KL+ ++ ++++E
Sbjct: 155 KEEVTKERDQLLSEVVKLRESLAQTTEQQQE 185
Score = 31.2 bits (69), Expect = 1.2
Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 7/112 (6%)
Query: 188 TLISQQATLLASNEA------FKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 241
T QQ T + EA F+++ + A + + ++L+K +D E
Sbjct: 179 TTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTE 238
Query: 242 VK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDR 292
+K L++ + K +LQKL+ +L K E+A ++ + ++ L +E ++
Sbjct: 239 IKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQ 290
Score = 28.9 bits (63), Expect = 6.2
Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 25/136 (18%)
Query: 183 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEV 242
L++L + +Q L NE K+ E K +EN+Q + E+
Sbjct: 253 LQKLEQQLKEQKIL---NERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALEL 309
Query: 243 KL-EEENRSLKADLQKL--------------KDELASTKQKLEKAENQVL-------AMR 280
K EEE ++ D+ KL +D+ A +Q E +NQ++ A +
Sbjct: 310 KAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASK 369
Query: 281 KQSEGLTKEYDRLLEE 296
KQ+E K D LL E
Sbjct: 370 KQAELDRKAMDELLRE 385
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 40.0 bits (92), Expect = 0.003
Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVG 238
L +LVTL+ ++ L +A + A E + ++ QL+ K +
Sbjct: 874 LEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEI 933
Query: 239 NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 293
NAE+ KLE+E LK D+ L+ LA +++ EN+V + ++ GL + +L
Sbjct: 934 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 993
Query: 294 LEEHAKLQAAVDGPMD 309
E LQ A +D
Sbjct: 994 TREKKALQEAHQQALD 1009
Score = 34.7 bits (78), Expect = 0.11
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
E KK E + + ++E +QL A+ GGK + KLE R L+ +L+ +
Sbjct: 1781 ERMKKNLEQTVKDLQHRLDEAEQL----ALKGGKKQIQ----KLETRIRELEFELEGEQK 1832
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
+ + + L K E +V + QSE K RL + KLQ V + EE
Sbjct: 1833 KNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1885
Score = 31.6 bits (70), Expect = 0.95
Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 14/83 (16%)
Query: 245 EEENRSLKADLQKLKDELASTKQKLEKAENQV-----------LAMRKQSEGL---TKEY 290
E+E ++K + QK KDELA ++ K ++ E ++ L ++ +SE L +
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
Query: 291 DRLLEEHAKLQAAVDGPMDKKEE 313
D+L++ +L+A + ++ E+
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAED 929
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
QQA L + +K+A+ A EA ++YMEE A++ LD AE + E + +
Sbjct: 134 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 304
+A L++ DEL +T ++ KAE + K S+G Y +L E++A+L+ A+
Sbjct: 192 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 240
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 259
E+ +++ E+ E + + + LK G + ++K LEE+N LK L +++
Sbjct: 185 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 244
Query: 260 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
D +S KQ+ K + + ++ E + ++ +RL EE ++ ++ +D
Sbjct: 245 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 290
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
QQA L + +K+A+ A EA ++YMEE A++ LD AE + E + +
Sbjct: 248 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 305
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 304
+A L++ DEL +T ++ KAE + K S+G Y +L E++A+L+ A+
Sbjct: 306 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 354
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 259
E+ +++ E+ E + + + LK G + ++K LEE+N LK L +++
Sbjct: 299 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 358
Query: 260 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
D +S KQ+ K + + ++ E + ++ +RL EE ++ ++ +D
Sbjct: 359 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 404
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
QQA L + +K+A+ A EA ++YMEE A++ LD AE + E + +
Sbjct: 134 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 304
+A L++ DEL +T ++ KAE + K S+G Y +L E++A+L+ A+
Sbjct: 192 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 240
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 259
E+ +++ E+ E + + + LK G + ++K LEE+N LK L +++
Sbjct: 185 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 244
Query: 260 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
D +S KQ+ K + + ++ E + ++ +RL EE ++ ++ +D
Sbjct: 245 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 290
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
QQA L + +K+A+ A EA ++YMEE A++ LD AE + E + +
Sbjct: 268 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 325
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 304
+A L++ DEL +T ++ KAE + K S+G Y +L E++A+L+ A+
Sbjct: 326 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 374
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 259
E+ +++ E+ E + + + LK G + ++K LEE+N LK L +++
Sbjct: 319 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 378
Query: 260 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
D +S KQ+ K + + ++ E + ++ +RL EE ++ ++ +D
Sbjct: 379 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 424
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/122 (19%), Positives = 63/122 (51%), Gaps = 2/122 (1%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
Q+ + +E +++ E E K + +E +++++ + + E K+ EE R
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 311
+ + +K+++E +++ EK + Q MR+Q E + ++ +++ E+ K+ + +++
Sbjct: 564 ERE-KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 312 EE 313
EE
Sbjct: 623 EE 624
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/169 (21%), Positives = 79/169 (46%), Gaps = 10/169 (5%)
Query: 144 TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAF 203
+EK +Q N ++ KL RA+ L + L + R+ L Q+ + E
Sbjct: 201 SEKSEIQLN---VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
Query: 204 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 263
+Q E E K E+ +++++ + + E +L E+ + L+ + +KL+++
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQ------EKRLREQEKELREQEKELR-EQKKLREQEE 310
Query: 264 STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKE 312
+++ EK Q MR+Q E + ++ +RL E+ +++ D++E
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Score = 36.6 bits (83), Expect = 0.030
Identities = 23/122 (18%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 192 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 251
Q+ + E ++Q E E +K E+ +++ + K+ E K++E+ +
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE----KMWEQEEEDKMQEQEEMM 634
Query: 252 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 311
+K++++ ++ EK Q MR+Q E + + +++ E+ K+Q + +++
Sbjct: 635 WEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Query: 312 EE 313
E+
Sbjct: 695 EK 696
Score = 32.3 bits (72), Expect = 0.56
Identities = 33/186 (17%), Positives = 79/186 (42%), Gaps = 26/186 (13%)
Query: 135 REIRKYDDVT--EKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQ 192
++IRK ++ ++ L+ G M K+ R ++ L R + +
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL-------------REQEKELRE 294
Query: 193 QATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 252
Q L + ++Q E E +K E+ +++++ + E +L E+ + ++
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE------KMWRQEERLWEQEKQMR 348
Query: 253 ADLQKLKDELASTKQKLEKAENQVLAMRKQ-----SEGLTKEYDRLLEEHAKLQAAVDGP 307
QK++D+ ++ E+ + MR+Q E +E +R+ E K++ +
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 308 MDKKEE 313
+++E+
Sbjct: 409 REQEEK 414
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 14/98 (14%)
Query: 211 SEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLE 270
++ +++ +E + LK+ AA +L L+EEN L +L + +DE+ S QKLE
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSA------LQEENVKLAEELGRSRDEVTS-HQKLE 1154
Query: 271 K----AENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 304
+ NQ+L M+K+ K+ D EE A LQ ++
Sbjct: 1155 EERSVLNNQLLEMKKRESKFIKDAD---EEKASLQKSI 1189
Score = 36.2 bits (82), Expect = 0.039
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Query: 205 KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGN---AEVKLEEENRSLKADLQKLKDE 261
K +S EAAKK+ EE +L++ + K++ + E+K E R+ K ++
Sbjct: 939 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSETKTKHEEI 997
Query: 262 LASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 303
L + ++ L E+++ R+++ GL +E + L ++ K +AA
Sbjct: 998 LQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA 1039
Score = 36.2 bits (82), Expect = 0.039
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Query: 192 QQATLLASNEAFKKQAESASEA--AKKYMEENDQLKKGAAVDGGKL-DVGNAEVKLEEEN 248
+ + LL E +KQA+ A A A+ M+ +Q+ K L D KL+ E
Sbjct: 1018 ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1077
Query: 249 RSLKA-------DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
+LK +L K K+ L QK+E+ ++ +++ + +++ L EE+ KL
Sbjct: 1078 DTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1136
Score = 31.2 bits (69), Expect = 1.2
Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Query: 128 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 187
LL +DA+R+ + +E L+ A E +K ++N + S + L R +
Sbjct: 727 LLDLDALRKASS-EGKSEMKKLRQQLEAAEK-QIKHLEIEKNAESSKASSITRELQGREL 784
Query: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247
L + Q L ++ + + +K+ E +++ +V + N + EE+
Sbjct: 785 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEE---AVSVQRSMQETVNKLHQKEEQ 841
Query: 248 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 295
L +DL+KL++ LA + K + + + + K E L + +++
Sbjct: 842 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 889
Score = 29.3 bits (64), Expect = 4.7
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 24/191 (12%)
Query: 136 EIRKYDDVTEKVNLQNNPGAMEHFHMK----LFRAQRNLYIAGFSL-------------L 178
E+ + D E +L+ + GA E H K L+ A L SL +
Sbjct: 514 EVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDV 573
Query: 179 LSFLLRRLVTLI-SQQATLLASNEAFKKQ--AESASEAAKKYMEENDQLKKGAAVDGGKL 235
++ +L T I S Q + +F K E+A A K E +L ++ +
Sbjct: 574 IALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQN 633
Query: 236 DVGNAEVKLEEENRSLKADLQKL----KDELASTKQKLEKAENQVLAMRKQSEGLTKEYD 291
+ +E +L+A L K+ ++ L + + KL+KAE+Q L + + +E +
Sbjct: 634 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 693
Query: 292 RLLEEHAKLQA 302
++E LQA
Sbjct: 694 IKVKELEVLQA 704
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 14/98 (14%)
Query: 211 SEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLE 270
++ +++ +E + LK+ AA +L L+EEN L +L + +DE+ S QKLE
Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSA------LQEENVKLAEELGRSRDEVTS-HQKLE 1189
Query: 271 K----AENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 304
+ NQ+L M+K+ K+ D EE A LQ ++
Sbjct: 1190 EERSVLNNQLLEMKKRESKFIKDAD---EEKASLQKSI 1224
Score = 36.2 bits (82), Expect = 0.039
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Query: 205 KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGN---AEVKLEEENRSLKADLQKLKDE 261
K +S EAAKK+ EE +L++ + K++ + E+K E R+ K ++
Sbjct: 974 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSETKTKHEEI 1032
Query: 262 LASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 303
L + ++ L E+++ R+++ GL +E + L ++ K +AA
Sbjct: 1033 LQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA 1074
Score = 36.2 bits (82), Expect = 0.039
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Query: 192 QQATLLASNEAFKKQAESASEA--AKKYMEENDQLKKGAAVDGGKL-DVGNAEVKLEEEN 248
+ + LL E +KQA+ A A A+ M+ +Q+ K L D KL+ E
Sbjct: 1053 ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1112
Query: 249 RSLKA-------DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
+LK +L K K+ L QK+E+ ++ +++ + +++ L EE+ KL
Sbjct: 1113 DTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1171
Score = 31.2 bits (69), Expect = 1.2
Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 5/168 (2%)
Query: 128 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 187
LL +DA+R+ + +E L+ A E +K ++N + S + L R +
Sbjct: 762 LLDLDALRKASS-EGKSEMKKLRQQLEAAEK-QIKHLEIEKNAESSKASSITRELQGREL 819
Query: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247
L + Q L ++ + + +K+ E +++ +V + N + EE+
Sbjct: 820 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEE---AVSVQRSMQETVNKLHQKEEQ 876
Query: 248 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 295
L +DL+KL++ LA + K + + + + K E L + +++
Sbjct: 877 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 924
Score = 29.3 bits (64), Expect = 4.7
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 24/191 (12%)
Query: 136 EIRKYDDVTEKVNLQNNPGAMEHFHMK----LFRAQRNLYIAGFSL-------------L 178
E+ + D E +L+ + GA E H K L+ A L SL +
Sbjct: 549 EVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDV 608
Query: 179 LSFLLRRLVTLI-SQQATLLASNEAFKKQ--AESASEAAKKYMEENDQLKKGAAVDGGKL 235
++ +L T I S Q + +F K E+A A K E +L ++ +
Sbjct: 609 IALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQN 668
Query: 236 DVGNAEVKLEEENRSLKADLQKL----KDELASTKQKLEKAENQVLAMRKQSEGLTKEYD 291
+ +E +L+A L K+ ++ L + + KL+KAE+Q L + + +E +
Sbjct: 669 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 728
Query: 292 RLLEEHAKLQA 302
++E LQA
Sbjct: 729 IKVKELEVLQA 739
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/83 (26%), Positives = 45/83 (54%)
Query: 219 EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLA 278
E+N ++ L V + +++E N +L+A+ Q LK +L + + + Q+LA
Sbjct: 1026 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1085
Query: 279 MRKQSEGLTKEYDRLLEEHAKLQ 301
+++Q+ L ++ L ++AKLQ
Sbjct: 1086 LQRQTVSLQEQNTTLQTQNAKLQ 1108
Score = 38.9 bits (89), Expect = 0.006
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 185 RLVTLISQQATLLASNEAFK---KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 241
RL+ + ATL A +A K KQ E+ + + + + L NA
Sbjct: 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA- 1105
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301
KL+ EN +L + L ++ A + EN+ ++ K+ E L YD L+++H KL+
Sbjct: 1106 -KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1164
Score = 37.0 bits (84), Expect = 0.023
Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 26/141 (18%)
Query: 183 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYME---------------------EN 221
LRR V + + +A + K+ ES E KK +E EN
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765
Query: 222 DQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMR 280
+L+K K+ +E++ LE EN++L+ +L++LK + ++LE+ E + ++
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK----ISSKRLEQLEKENKSLE 821
Query: 281 KQSEGLTKEYDRLLEEHAKLQ 301
+++ L K+ +L +E+ +L+
Sbjct: 822 QETSQLEKDKKQLEKENKRLR 842
Score = 34.3 bits (77), Expect = 0.15
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 238 GNAE--VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 295
GNA +K+E+EN+ L ++ L++E+ KQ L+ +N + K+ L K + L E
Sbjct: 488 GNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE 547
Score = 33.9 bits (76), Expect = 0.19
Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLD----- 236
L+ + L+ QQ++L NE+ K+ E ++++++L+ + +
Sbjct: 1121 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 1180
Query: 237 ---VGNAEVKLEEENRSLK---ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEY 290
+ +A LE E+R L+ L K K +L ++ L+ + ++L K E + EY
Sbjct: 1181 HGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1240
Query: 291 DRLLEEHAKL 300
+L E+ +L
Sbjct: 1241 KKLCGENDRL 1250
Score = 31.6 bits (70), Expect = 0.95
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+KLE EN+S L K +EL +T +E +++L M K+++ L+K+ + L E
Sbjct: 463 LKLEMENQS----LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
Score = 31.6 bits (70), Expect = 0.95
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 17/108 (15%)
Query: 201 EAFKKQAESASEAAKKYM---EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK 257
E +K++ E A E + +EN+ L+K + K+ E LE+EN L+ + +K
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQK--KITNLKITCEKIEA-LEQENSELERENRK 674
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
LK L S K + Q E L KE +L EE+ +L+ V+
Sbjct: 675 LKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVE 711
Score = 30.0 bits (66), Expect = 2.8
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 185 RLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVGNAE 241
+L + +S+ L E +K + E E + +E L+ +G KL
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLH----- 378
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEK--AENQVLAM-RKQS 283
+LE+EN LKA L ++ E ++K+E+ EN L M +KQS
Sbjct: 379 -ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/83 (26%), Positives = 45/83 (54%)
Query: 219 EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLA 278
E+N ++ L V + +++E N +L+A+ Q LK +L + + + Q+LA
Sbjct: 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1084
Query: 279 MRKQSEGLTKEYDRLLEEHAKLQ 301
+++Q+ L ++ L ++AKLQ
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQ 1107
Score = 38.9 bits (89), Expect = 0.006
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 185 RLVTLISQQATLLASNEAFK---KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 241
RL+ + ATL A +A K KQ E+ + + + + L NA
Sbjct: 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA- 1104
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301
KL+ EN +L + L ++ A + EN+ ++ K+ E L YD L+++H KL+
Sbjct: 1105 -KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1163
Score = 37.0 bits (84), Expect = 0.023
Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 26/141 (18%)
Query: 183 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYME---------------------EN 221
LRR V + + +A + K+ ES E KK +E EN
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765
Query: 222 DQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMR 280
+L+K K+ +E++ LE EN++L+ +L++LK + ++LE+ E + ++
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK----ISSKRLEQLEKENKSLE 821
Query: 281 KQSEGLTKEYDRLLEEHAKLQ 301
+++ L K+ +L +E+ +L+
Sbjct: 822 QETSQLEKDKKQLEKENKRLR 842
Score = 34.3 bits (77), Expect = 0.15
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 238 GNAE--VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 295
GNA +K+E+EN+ L ++ L++E+ KQ L+ +N + K+ L K + L E
Sbjct: 488 GNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE 547
Score = 33.9 bits (76), Expect = 0.19
Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLD----- 236
L+ + L+ QQ++L NE+ K+ E ++++++L+ + +
Sbjct: 1120 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 1179
Query: 237 ---VGNAEVKLEEENRSLK---ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEY 290
+ +A LE E+R L+ L K K +L ++ L+ + ++L K E + EY
Sbjct: 1180 HGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1239
Query: 291 DRLLEEHAKL 300
+L E+ +L
Sbjct: 1240 KKLCGENDRL 1249
Score = 31.6 bits (70), Expect = 0.95
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+KLE EN+S L K +EL +T +E +++L M K+++ L+K+ + L E
Sbjct: 463 LKLEMENQS----LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
Score = 31.6 bits (70), Expect = 0.95
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 17/108 (15%)
Query: 201 EAFKKQAESASEAAKKYM---EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK 257
E +K++ E A E + +EN+ L+K + K+ E LE+EN L+ + +K
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQK--KITNLKITCEKIEA-LEQENSELERENRK 674
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 305
LK L S K + Q E L KE +L EE+ +L+ V+
Sbjct: 675 LKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVE 711
Score = 30.0 bits (66), Expect = 2.8
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 185 RLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVGNAE 241
+L + +S+ L E +K + E E + +E L+ +G KL
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLH----- 378
Query: 242 VKLEEENRSLKADLQKLKDELASTKQKLEK--AENQVLAM-RKQS 283
+LE+EN LKA L ++ E ++K+E+ EN L M +KQS
Sbjct: 379 -ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Query: 178 LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 237
LL L+ L ++ + A K++ E + +EE + +G + + +
Sbjct: 891 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 948
Query: 238 GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+ LEE+ +A QKL+ E + + K++K E+++L M Q+ L+KE +LLEE
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1006
Score = 34.3 bits (77), Expect = 0.15
Identities = 15/43 (34%), Positives = 29/43 (67%)
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
++Q +DEL TK++ +KAEN++ + ++ LT+E + L E+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Score = 31.6 bits (70), Expect = 0.95
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 199 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 257
S EA Q + AA++ ++ D K+ A + L NA L++E R L+A + +
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1740
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 289
L++EL + +E ++V +Q+E L+ E
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)
Query: 200 NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 257
NEA K + A + A + D + KL+V +LEEE SL+ L +
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 258 ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 298
L +L+ +K+KL+ + V A+ +K+ E LT++Y+ +
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416
Query: 299 KLQ 301
KL+
Sbjct: 1417 KLE 1419
Score = 29.6 bits (65), Expect = 3.6
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 166 AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 223
A++NL +I+ ++ LS ++L S L + F+K+ E+ ++ ++ D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 224 LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 282
L+K + +L++E L DL + +L S +K ++ +Q+LA K
Sbjct: 1418 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1463
Query: 283 SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 313
S E DR E + L A++ ++ KEE
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Score = 29.3 bits (64), Expect = 4.7
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)
Query: 214 AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 264
AK +++N Q L+K A G+L V G A+ ++E + + L+A +Q+L+ + A
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 265 TKQKLEKAENQV---LAMRKQSEG 285
K+ K +N+V M ++EG
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEG 1301
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Query: 178 LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 237
LL L+ L ++ + A K++ E + +EE + +G + + +
Sbjct: 898 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 955
Query: 238 GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+ LEE+ +A QKL+ E + + K++K E+++L M Q+ L+KE +LLEE
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1013
Score = 34.3 bits (77), Expect = 0.15
Identities = 15/43 (34%), Positives = 29/43 (67%)
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
++Q +DEL TK++ +KAEN++ + ++ LT+E + L E+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902
Score = 31.6 bits (70), Expect = 0.95
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 199 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 257
S EA Q + AA++ ++ D K+ A + L NA L++E R L+A + +
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1747
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 289
L++EL + +E ++V +Q+E L+ E
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)
Query: 200 NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 257
NEA K + A + A + D + KL+V +LEEE SL+ L +
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 258 ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 298
L +L+ +K+KL+ + V A+ +K+ E LT++Y+ +
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423
Query: 299 KLQ 301
KL+
Sbjct: 1424 KLE 1426
Score = 29.6 bits (65), Expect = 3.6
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 166 AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 223
A++NL +I+ ++ LS ++L S L + F+K+ E+ ++ ++ D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 224 LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 282
L+K + +L++E L DL + +L S +K ++ +Q+LA K
Sbjct: 1425 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1470
Query: 283 SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 313
S E DR E + L A++ ++ KEE
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508
Score = 29.3 bits (64), Expect = 4.7
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)
Query: 214 AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 264
AK +++N Q L+K A G+L V G A+ ++E + + L+A +Q+L+ + A
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 265 TKQKLEKAENQV---LAMRKQSEG 285
K+ K +N+V M ++EG
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEG 1308
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Query: 178 LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 237
LL L+ L ++ + A K++ E + +EE + +G + + +
Sbjct: 898 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 955
Query: 238 GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+ LEE+ +A QKL+ E + + K++K E+++L M Q+ L+KE +LLEE
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1013
Score = 34.3 bits (77), Expect = 0.15
Identities = 15/43 (34%), Positives = 29/43 (67%)
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
++Q +DEL TK++ +KAEN++ + ++ LT+E + L E+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902
Score = 31.6 bits (70), Expect = 0.95
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 199 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 257
S EA Q + AA++ ++ D K+ A + L NA L++E R L+A + +
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1747
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 289
L++EL + +E ++V +Q+E L+ E
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)
Query: 200 NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 257
NEA K + A + A + D + KL+V +LEEE SL+ L +
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 258 ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 298
L +L+ +K+KL+ + V A+ +K+ E LT++Y+ +
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423
Query: 299 KLQ 301
KL+
Sbjct: 1424 KLE 1426
Score = 29.6 bits (65), Expect = 3.6
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 166 AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 223
A++NL +I+ ++ LS ++L S L + F+K+ E+ ++ ++ D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 224 LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 282
L+K + +L++E L DL + +L S +K ++ +Q+LA K
Sbjct: 1425 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1470
Query: 283 SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 313
S E DR E + L A++ ++ KEE
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508
Score = 29.3 bits (64), Expect = 4.7
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)
Query: 214 AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 264
AK +++N Q L+K A G+L V G A+ ++E + + L+A +Q+L+ + A
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 265 TKQKLEKAENQV---LAMRKQSEG 285
K+ K +N+V M ++EG
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEG 1308
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Query: 178 LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 237
LL L+ L ++ + A K++ E + +EE + +G + + +
Sbjct: 891 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 948
Query: 238 GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+ LEE+ +A QKL+ E + + K++K E+++L M Q+ L+KE +LLEE
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1006
Score = 34.3 bits (77), Expect = 0.15
Identities = 15/43 (34%), Positives = 29/43 (67%)
Query: 254 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
++Q +DEL TK++ +KAEN++ + ++ LT+E + L E+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Score = 31.6 bits (70), Expect = 0.95
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 199 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 257
S EA Q + AA++ ++ D K+ A + L NA L++E R L+A + +
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1740
Query: 258 LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 289
L++EL + +E ++V +Q+E L+ E
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)
Query: 200 NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 257
NEA K + A + A + D + KL+V +LEEE SL+ L +
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 258 ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 298
L +L+ +K+KL+ + V A+ +K+ E LT++Y+ +
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416
Query: 299 KLQ 301
KL+
Sbjct: 1417 KLE 1419
Score = 29.6 bits (65), Expect = 3.6
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 166 AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 223
A++NL +I+ ++ LS ++L S L + F+K+ E+ ++ ++ D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 224 LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 282
L+K + +L++E L DL + +L S +K ++ +Q+LA K
Sbjct: 1418 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1463
Query: 283 SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 313
S E DR E + L A++ ++ KEE
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Score = 29.3 bits (64), Expect = 4.7
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)
Query: 214 AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 264
AK +++N Q L+K A G+L V G A+ ++E + + L+A +Q+L+ + A
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 265 TKQKLEKAENQV---LAMRKQSEG 285
K+ K +N+V M ++EG
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEG 1301
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 39.3 bits (90), Expect = 0.005
Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 8/136 (5%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG--- 238
L ++V+L+ ++ L +A + A E + ++ QL+ +L+
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 934
Query: 239 NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 293
NAE+ KLE+E LK D+ L+ LA +++ EN+V + ++ GL + +L
Sbjct: 935 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994
Query: 294 LEEHAKLQAAVDGPMD 309
+E LQ A +D
Sbjct: 995 TKEKKALQEAHQQALD 1010
Score = 33.9 bits (76), Expect = 0.19
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 201 EAFKKQAESASEAAKKYME--ENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKL 258
E K + +SA E A+ +E E L+ + K ++ + +EE K + Q++
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV 1595
Query: 259 KDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 303
D L ++ ++ N+VL ++K+ EG E + L HA AA
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL-SHANRMAA 1639
Score = 33.9 bits (76), Expect = 0.19
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
E KK E + + ++E +Q+ A+ GGK + KLE R L+ +L+ +
Sbjct: 1782 ERMKKNMEQTIKDLQHRLDEAEQI----ALKGGKKQLQ----KLEARVRELEGELEAEQK 1833
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
A + + + K+E ++ + Q+E K RL + KLQ V + EE
Sbjct: 1834 RNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886
Score = 30.4 bits (67), Expect = 2.1
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)
Query: 190 ISQQATLLASNEAFKKQAESASEAAKKYME-------------ENDQLKKGAAVDGGKLD 236
+ QQ L + +K+ E AK+ +E END+L+ + + D
Sbjct: 1029 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088
Query: 237 VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE- 295
+ K+E+E + L LQK E + ++LE+ R + E L + R LE
Sbjct: 1089 INQQNSKIEDE-QVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 296 -----EHAKLQAAVDGPMDKKEE 313
E A +V M+KK E
Sbjct: 1148 ISERLEEAGGATSVQIEMNKKRE 1170
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 189 LISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEEN 248
L ++Q L + E +S + K E +++L+ V+ D+ KLE+E
Sbjct: 940 LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNA---DLAARRRKLEDEC 996
Query: 249 RSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 303
LK D+ LK LA +++ + EN+V + ++ L + RL +E LQ A
Sbjct: 997 TELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEA 1051
Score = 36.2 bits (82), Expect = 0.039
Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
E KK E + +EE +Q AA+ GGK V KLE + R L+A+L +
Sbjct: 1829 ERMKKTLEQTVRELQARLEEAEQ----AALRGGKKQVQ----KLEAKVRELEAELDAEQK 1880
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
+ A + + K E +V + Q+E K R+ + KLQ+ V + EE
Sbjct: 1881 KHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Score = 33.5 bits (75), Expect = 0.25
Identities = 35/154 (22%), Positives = 72/154 (46%), Gaps = 27/154 (17%)
Query: 187 VTLISQQATLLASN--------EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG 238
VTL ++AT A+ E ++ E ++ +E + +G + +L G
Sbjct: 1477 VTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536
Query: 239 NAEV-----KLEEENRSLKADLQKLKD----------ELASTKQKLEKAENQVLAMRKQS 283
+ E L+ EN++L+ ++ L D EL TK+ LE ++++ A +++
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 284 EGLTKEYD----RLLEEHAKLQAAVDGPMDKKEE 313
EG + + R+ E ++++A VD + +K+E
Sbjct: 1597 EGALELEETKTLRIQLELSQVKAEVDRKLAEKDE 1630
Score = 31.2 bits (69), Expect = 1.2
Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
+A ++AE A E +EE L+ + K +V + +EE +L+ + Q+ +
Sbjct: 1590 QAALEEAEGALE-----LEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVE 1644
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 302
L ++ +A N+ L ++K+ EG + + L HA QA
Sbjct: 1645 SLQASLDAETRARNEALRLKKKMEGDLNDLELQL-GHATRQA 1685
Score = 30.0 bits (66), Expect = 2.8
Identities = 22/100 (22%), Positives = 46/100 (46%), Gaps = 2/100 (2%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
E +++AE+ +E + + N ++ + + + D +LEE + L LQ+ ++
Sbjct: 1394 EQHEEEAEAQAELQRLLSKANAEVAQWRSKY--EADAIQRTEELEEAKKKLALRLQEAEE 1451
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 300
+ + K E L ++ +SE +T E +R A L
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAAL 1491
Score = 29.6 bits (65), Expect = 3.6
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 204 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 263
K ES ++AA+ + ++LKK + ++ +++E+E + L A +QK EL
Sbjct: 1109 KLTQESVADAAQDKQQLEEKLKKKDS------ELSQLSLRVEDE-QLLGAQMQKKIKELQ 1161
Query: 264 STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 296
+ ++LE+ A R + E E R LEE
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEE 1194
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 14/111 (12%)
Query: 195 TLLASNEAFKKQAES--ASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 252
+LL + + KK ES E + + + L+ G + + + N +E E + L+
Sbjct: 48 SLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLR 107
Query: 253 ADLQKL-------KDELASTKQKLEKAENQVLAMRKQSEGL-----TKEYD 291
A +++L +DELA+T+QKL+K+E V + ++ + L K+YD
Sbjct: 108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYD 158
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 38.9 bits (89), Expect = 0.006
Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 8/136 (5%)
Query: 182 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG--- 238
L ++V+L+ ++ L +A + A E + ++ QL+ +L+
Sbjct: 873 LEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 932
Query: 239 NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 293
NAE+ KLE+E LK D+ L+ LA +++ EN+V + ++ GL + +L
Sbjct: 933 NAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 992
Query: 294 LEEHAKLQAAVDGPMD 309
+E LQ A +D
Sbjct: 993 TKEKKALQEAHQQALD 1008
Score = 33.1 bits (74), Expect = 0.33
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 260
E KK E + + ++E +Q+ A+ GGK + KLE R L+ +L+ +
Sbjct: 1780 ERMKKNMEQTIKDLQHRLDEAEQI----ALKGGKKQLQ----KLEARVRELENELEAEQK 1831
Query: 261 ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 313
A + + + K+E ++ + Q+E K RL + KLQ V + EE
Sbjct: 1832 RNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Score = 29.6 bits (65), Expect = 3.6
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 16/122 (13%)
Query: 201 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLK- 259
EA + +A+ KK+ + +L G +D ++ + KLE+E K +L +
Sbjct: 1180 EATLQHEATAAALRKKHADSVAEL--GEQID----NLQRVKQKLEKEKSEFKLELDDVTS 1233
Query: 260 --DELASTKQKLEKA----ENQVLAMRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDK 310
+++ K LEK E+Q+ R ++E + + L + AKLQ + +D+
Sbjct: 1234 NMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDE 1293
Query: 311 KE 312
KE
Sbjct: 1294 KE 1295
Score = 28.5 bits (62), Expect = 8.0
Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 190 ISQQATLLASNEAFKKQAESASEAAKKYME-------------ENDQLKKGAAVDGGKLD 236
+ QQ L + +K+ E AK+ +E END+ + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 237 VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE- 295
+ ++E+E ++L + LQK EL + ++LE+ R + E L + R LE
Sbjct: 1087 LNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
Query: 296 -----EHAKLQAAVDGPMDKKEE 313
E A +V M+KK E
Sbjct: 1146 ISERLEEAGGATSVQIEMNKKRE 1168
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 14/111 (12%)
Query: 195 TLLASNEAFKKQAES--ASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 252
+LL + + KK ES E + + + L+ G + + + N +E E + L+
Sbjct: 48 SLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLR 107
Query: 253 ADLQKL-------KDELASTKQKLEKAENQVLAMRKQSEGL-----TKEYD 291
A +++L +DELA+T+QKL+K+E V + ++ + L K+YD
Sbjct: 108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYD 158
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,051,105
Number of Sequences: 37866
Number of extensions: 392378
Number of successful extensions: 4952
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 363
Number of HSP's that attempted gapping in prelim test: 3167
Number of HSP's gapped (non-prelim): 2025
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.