Search of human proteins with 21264341

Search of human proteins with 21264341

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21264341 spermine synthase [Homo sapiens]
         (366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21264341 spermine synthase [Homo sapiens]                          744   0.0  
gi|63253298 spermidine synthase [Homo sapiens]                         69   7e-12
gi|156104874 envoplakin [Homo sapiens]                                 35   0.14 
gi|195927017 phosphatidylinositol transfer protein, membrane-ass...    30   3.4  
gi|195927015 phosphatidylinositol transfer protein, membrane-ass...    30   3.4  
gi|122937211 KIAA0368 protein [Homo sapiens]                           30   4.5  
gi|109689703 gasdermin-like isoform 1 [Homo sapiens]                   29   5.8  
gi|109689711 gasdermin-like isoform 2 [Homo sapiens]                   29   5.8  
gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]           29   5.8  
gi|188595687 gamma filamin isoform b [Homo sapiens]                    29   7.6  
gi|116805322 gamma filamin isoform a [Homo sapiens]                    29   7.6  
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          29   7.6  

>gi|21264341 spermine synthase [Homo sapiens]
          Length = 366

 Score =  744 bits (1921), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 1   MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFAN 60
           MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFAN
Sbjct: 1   MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFAN 60

Query: 61  LRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAI 120
           LRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAI
Sbjct: 61  LRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAI 120

Query: 121 DRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRA 180
           DRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRA
Sbjct: 121 DRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRA 180

Query: 181 IMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV 240
           IMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV
Sbjct: 181 IMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV 240

Query: 241 LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD 300
           LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD
Sbjct: 241 LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD 300

Query: 301 LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTV 360
           LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTV
Sbjct: 301 LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTV 360

Query: 361 WKKAKP 366
           WKKAKP
Sbjct: 361 WKKAKP 366


>gi|63253298 spermidine synthase [Homo sapiens]
          Length = 302

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 58/203 (28%), Positives = 92/203 (45%), Gaps = 29/203 (14%)

Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 182
           WP   G+ +   ++++++   S YQ+I +  SK +GN+L+L G +   E D  +Y   I 
Sbjct: 28  WP---GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIA 84

Query: 183 GSGKEDYTG-KDVLILGGGDGGILCEIVK-LKPKMVTMVEIDQMVIDGCKKYMRKTC--- 237
                 +   + VLI+GGGDGG+L E+VK    + V   EID+ VI   KK++       
Sbjct: 85  NLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGY 144

Query: 238 -GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGRE-FDYVINDLTAVPISTSPEEDSTWEFL 295
               L    GD ++            + K+ ++ FD +I D      S+ P   +   F 
Sbjct: 145 SSSKLTLHVGDGFE------------FMKQNQDAFDVIITD------SSDPMGPAESLFK 186

Query: 296 RLILDLSMKVLKQDGKYFTQGNC 318
                L    LK+DG    QG C
Sbjct: 187 ESYYQLMKTALKEDGVLCCQGEC 209


>gi|156104874 envoplakin [Homo sapiens]
          Length = 2033

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 276  DLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRL 335
            +L+ +  +   E+D  +E  R + DL  KV +++    TQ    NL+  +S+ E + G+ 
Sbjct: 1637 ELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRETNLSTKISILEPETGKD 1696

Query: 336  YCPVE-FSKEIVCVPSYLELWVFYTVWKK 363
              P E + + I+    YL+L      W++
Sbjct: 1697 MSPYEAYKRGIIDRGQYLQLQELECDWEE 1725


>gi|195927017 phosphatidylinositol transfer protein,
            membrane-associated isoform b [Homo sapiens]
          Length = 1243

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 9/70 (12%)

Query: 34   GMAESVHTWQDHGYLATYTNKNGSFANLRI--------YPHGLV-LLDLQSYDGDAQGKE 84
            G  + V  WQD GYL  Y          R+        +PHG+V   D  ++D   Q   
Sbjct: 1046 GAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAM 1105

Query: 85   EIDSILNKVE 94
             + S++ +VE
Sbjct: 1106 FLQSLVQEVE 1115


>gi|195927015 phosphatidylinositol transfer protein,
            membrane-associated isoform a [Homo sapiens]
          Length = 1244

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 9/70 (12%)

Query: 34   GMAESVHTWQDHGYLATYTNKNGSFANLRI--------YPHGLV-LLDLQSYDGDAQGKE 84
            G  + V  WQD GYL  Y          R+        +PHG+V   D  ++D   Q   
Sbjct: 1047 GAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAM 1106

Query: 85   EIDSILNKVE 94
             + S++ +VE
Sbjct: 1107 FLQSLVQEVE 1116


>gi|122937211 KIAA0368 protein [Homo sapiens]
          Length = 2017

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 5/87 (5%)

Query: 222  DQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVP 281
            D+ ++D   KY+++   D++ NL  + ++V    C+ +       GR  D +I+ L  + 
Sbjct: 1324 DKSMVD---KYLKEILQDLVKNLTSNMWRVRESSCLAL--NDLLRGRPLDDIIDKLPEIW 1378

Query: 282  ISTSPEEDSTWEFLRLILDLSMKVLKQ 308
             +    +D   E +R   +L++K L +
Sbjct: 1379 ETLFRVQDDIKESVRKAAELALKTLSK 1405


>gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
          Length = 403

 Score = 29.3 bits (64), Expect = 5.8
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 57  SFANLRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQ-DSTGR-VKRLP 112
           +F   R Y  GL L+D+   DGD +  +E+DS L   +   + L   DSTG  + RLP
Sbjct: 45  TFFGCRHYTTGLTLMDILDTDGD-KWLDELDSGLQGQKAEFQILDNVDSTGELIVRLP 101


>gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
          Length = 394

 Score = 29.3 bits (64), Expect = 5.8
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 57  SFANLRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQ-DSTGR-VKRLP 112
           +F   R Y  GL L+D+   DGD +  +E+DS L   +   + L   DSTG  + RLP
Sbjct: 45  TFFGCRHYTTGLTLMDILDTDGD-KWLDELDSGLQGQKAEFQILDNVDSTGELIVRLP 101


>gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
          Length = 524

 Score = 29.3 bits (64), Expect = 5.8
 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 6/59 (10%)

Query: 184 SGKEDYTGKDVLILGGGDGGILC--EIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV 240
           +G+ DY   D+L++GGG GG+ C  E  +L  K V +V+  +    G +  +  TC +V
Sbjct: 35  AGQRDY---DLLVVGGGSGGLACAKEAAQLGRK-VAVVDYVEPSPQGTRWGLGGTCVNV 89


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 28.9 bits (63), Expect = 7.6
 Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 29/120 (24%)

Query: 122 RYWPTADGRLVEYDIDEVVYDED---SPYQNIKILHS------------KQFGNILILSG 166
           RYWPT  G   EY +  +  DED   SP+    I H             K FG  L  +G
Sbjct: 629 RYWPTEPG---EYAVHVICDDEDIRDSPF----IAHILPAPPDCFPDKVKAFGPGLEPTG 681

Query: 167 DVNLAESDLAYTRAIMGSGK-----EDYTGK--DVLILGGGDGGILCEIVKLKPKMVTMV 219
            +    ++        G G      +D  G   D+ ++  GDG   C  V  KP   T++
Sbjct: 682 CIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTII 741


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 28.9 bits (63), Expect = 7.6
 Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 29/120 (24%)

Query: 122 RYWPTADGRLVEYDIDEVVYDED---SPYQNIKILHS------------KQFGNILILSG 166
           RYWPT  G   EY +  +  DED   SP+    I H             K FG  L  +G
Sbjct: 629 RYWPTEPG---EYAVHVICDDEDIRDSPF----IAHILPAPPDCFPDKVKAFGPGLEPTG 681

Query: 167 DVNLAESDLAYTRAIMGSGK-----EDYTGK--DVLILGGGDGGILCEIVKLKPKMVTMV 219
            +    ++        G G      +D  G   D+ ++  GDG   C  V  KP   T++
Sbjct: 682 CIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTII 741


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 28.9 bits (63), Expect = 7.6
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 126 TADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSG 185
           T DGR +E  + E+  + D P   +K    ++ G      G    A  +    + +  +G
Sbjct: 101 TEDGRALEGTLSELAAETDLPVVFVK---QRKIGG----HGPTLKAYQEGRLQKLLKMNG 153

Query: 186 KEDYTGK---DVLILGGGDGGI 204
            ED       D++I+GGG GG+
Sbjct: 154 PEDLPKSYDYDLIIIGGGSGGL 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,729,592
Number of Sequences: 37866
Number of extensions: 606598
Number of successful extensions: 1451
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1443
Number of HSP's gapped (non-prelim): 12
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.