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Search of human proteins with 113424103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113424103 PREDICTED: hypothetical protein [Homo sapiens]
(181 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169206039 PREDICTED: hypothetical protein [Homo sapiens] 350 4e-97
gi|113424287 PREDICTED: hypothetical protein [Homo sapiens] 350 4e-97
gi|113424103 PREDICTED: hypothetical protein [Homo sapiens] 350 4e-97
gi|113427727 PREDICTED: hypothetical protein [Homo sapiens] 314 2e-86
gi|169212923 PREDICTED: hypothetical protein [Homo sapiens] 312 1e-85
gi|17158023 hypothetical protein LOC85395 [Homo sapiens] 311 1e-85
gi|239752538 PREDICTED: hypothetical protein, partial [Homo sapi... 308 2e-84
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 42 2e-04
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 42 2e-04
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 42 2e-04
gi|148746195 trichohyalin [Homo sapiens] 39 0.002
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 35 0.027
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 35 0.027
gi|56549694 enabled homolog isoform a [Homo sapiens] 35 0.046
gi|39930375 enabled homolog isoform b [Homo sapiens] 35 0.046
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 35 0.046
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 35 0.046
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 35 0.046
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 35 0.046
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.046
gi|56118254 zinc finger protein 18 [Homo sapiens] 33 0.10
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 33 0.17
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 33 0.17
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 33 0.17
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 33 0.17
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 33 0.17
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 33 0.17
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 33 0.17
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 33 0.17
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 33 0.17
>gi|169206039 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 350 bits (898), Expect = 4e-97
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK
Sbjct: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
Query: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE
Sbjct: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
Query: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ
Sbjct: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
Query: 181 L 181
L
Sbjct: 181 L 181
>gi|113424287 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 350 bits (898), Expect = 4e-97
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK
Sbjct: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
Query: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE
Sbjct: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
Query: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ
Sbjct: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
Query: 181 L 181
L
Sbjct: 181 L 181
>gi|113424103 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 350 bits (898), Expect = 4e-97
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK
Sbjct: 1 MCELWLIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMK 60
Query: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE
Sbjct: 61 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRE 120
Query: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ
Sbjct: 121 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
Query: 181 L 181
L
Sbjct: 181 L 181
>gi|113427727 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 314 bits (805), Expect = 2e-86
Identities = 168/176 (95%), Positives = 169/176 (96%)
Query: 6 LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQ 65
LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQ
Sbjct: 6 LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQ 65
Query: 66 WLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPR 125
LQKIEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSRRQ SRESNKP
Sbjct: 66 CLQKIEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRRQACSRESNKPW 125
Query: 126 PSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL 181
PSELSRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLEDGGQL
Sbjct: 126 PSELSRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLEDGGQL 181
>gi|169212923 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 312 bits (799), Expect = 1e-85
Identities = 166/176 (94%), Positives = 168/176 (95%)
Query: 6 LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQ 65
LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKT+LPKKEKMKLRREQ
Sbjct: 27 LIRIIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTILPKKEKMKLRREQ 86
Query: 66 WLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPR 125
LQKIEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSR Q SRESNKP
Sbjct: 87 CLQKIEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRHQACSRESNKPW 146
Query: 126 PSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL 181
PSELSRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLEDGGQL
Sbjct: 147 PSELSRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLEDGGQL 202
>gi|17158023 hypothetical protein LOC85395 [Homo sapiens]
Length = 230
Score = 311 bits (798), Expect = 1e-85
Identities = 168/184 (91%), Positives = 168/184 (91%), Gaps = 15/184 (8%)
Query: 13 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 57
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
Query: 58 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTR 117
KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ R
Sbjct: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
Query: 118 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 177
SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED
Sbjct: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
Query: 178 GGQL 181
GGQL
Sbjct: 227 GGQL 230
>gi|239752538 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 172
Score = 308 bits (788), Expect = 2e-84
Identities = 164/172 (95%), Positives = 165/172 (95%)
Query: 10 IPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQK 69
IPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQ LQK
Sbjct: 1 IPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQCLQK 60
Query: 70 IEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSEL 129
IEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSRRQ SRESNKP PSEL
Sbjct: 61 IEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRRQACSRESNKPWPSEL 120
Query: 130 SRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL 181
SRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLEDGGQL
Sbjct: 121 SRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLEDGGQL 172
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 42.4 bits (98), Expect = 2e-04
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 16 TNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVL------PKKEKMKLRREQWLQK 69
T ++ + K D + K+ V T ++ G + KT+L P KEK + +E L K
Sbjct: 586 TQVYQKDKQDADRPLSKMNRAVNGET-LKTGGDNKTLLHLGSSAPGKEKSETDKETSLVK 644
Query: 70 IEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSEL 129
KL +Q+ REE P + + + G R +T +ES P +
Sbjct: 645 QTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSG 695
Query: 130 SRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 172
S R E +R + +E+L S + ++L RQ
Sbjct: 696 HSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo
sapiens]
Length = 1584
Score = 42.4 bits (98), Expect = 2e-04
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 16 TNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVL------PKKEKMKLRREQWLQK 69
T ++ + K D + K+ V T ++ G + KT+L P KEK + +E L K
Sbjct: 684 TQVYQKDKQDADRPLSKMNRAVNGET-LKTGGDNKTLLHLGSSAPGKEKSETDKETSLVK 742
Query: 70 IEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSEL 129
KL +Q+ REE P + + + G R +T +ES P +
Sbjct: 743 QTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSG 793
Query: 130 SRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 172
S R E +R + +E+L S + ++L RQ
Sbjct: 794 HSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 836
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
sapiens]
Length = 1460
Score = 42.4 bits (98), Expect = 2e-04
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 16 TNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVL------PKKEKMKLRREQWLQK 69
T ++ + K D + K+ V T ++ G + KT+L P KEK + +E L K
Sbjct: 586 TQVYQKDKQDADRPLSKMNRAVNGET-LKTGGDNKTLLHLGSSAPGKEKSETDKETSLVK 644
Query: 70 IEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSEL 129
KL +Q+ REE P + + + G R +T +ES P +
Sbjct: 645 QTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSG 695
Query: 130 SRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 172
S R E +R + +E+L S + ++L RQ
Sbjct: 696 HSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 38.9 bits (89), Expect = 0.002
Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 14/146 (9%)
Query: 34 ELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVG 93
E +R +RR + + + + +LRREQ L++ + + EQKH +ERR + +
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR--LKR 449
Query: 94 DLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQ---LLEEERTRFQE 150
+ RD L R + R + R +L R +R++ LEEE R Q+
Sbjct: 450 EQEERRDWL---------KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 151 LLASPAYRASPLVAIGQTLARQMQLE 176
R Q L RQ + E
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEE 526
Score = 35.8 bits (81), Expect = 0.021
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
Query: 32 KLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVV 91
KLE + R RR + + ++ + +L+R++ ++++ +EQ+ R E+ R +
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 92 VGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQEL 151
+ R LE R Q RE + R L R ++Q+L E+ R ++
Sbjct: 550 LKREEEKR--------LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 152 L 152
L
Sbjct: 602 L 602
Score = 35.0 bits (79), Expect = 0.035
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREER-RRRAT 89
++ E +R +RR + + + + +LRREQ L++ + ++ +Q RE++ RR
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 90 VVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQ 149
+ ++ + L E RR RE R + R +R Q EE R R+
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ-EEERRERWL 489
Query: 150 EL 151
+L
Sbjct: 490 KL 491
Score = 34.3 bits (77), Expect = 0.060
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 20/119 (16%)
Query: 38 RSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHP 97
R + + R + LP++E+ + RR Q ++ + ++ E++ + +RR RA L
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ----QLQE 851
Query: 98 LRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPA 156
D L +E + R S+ R R QL EE + R L A PA
Sbjct: 852 EEDGL----------------QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Score = 33.1 bits (74), Expect = 0.13
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 24/132 (18%)
Query: 34 ELDVRSVTSIRRGAEAKTVLPKKEK----MKLRREQ-----WLQKIEAIKLAEQKHREER 84
E +R +RR E + K E+ +L+REQ WL++ E + EQ+ R+++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 85 RRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLL--E 142
+R + L LE RR+ + R R +L R +R+Q L +
Sbjct: 476 LKR--------DQEEERRERWLKLEEEERREQQER-----REQQLRREQEERREQRLKRQ 522
Query: 143 EERTRFQELLAS 154
EE R Q+ L S
Sbjct: 523 EEEERLQQRLRS 534
Score = 32.7 bits (73), Expect = 0.17
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 9/119 (7%)
Query: 34 ELDVRSVTSIRRGAEAKTVLPK-KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVV 92
E + R ++R E + + + + + +LRREQ ++ + +K E+K E+ RR +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL-- 567
Query: 93 GDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQEL 151
+ +LL E R+Q RE + L R + + LE+E R Q L
Sbjct: 568 --KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR----EEVERLEQEERREQRL 620
Score = 32.3 bits (72), Expect = 0.23
Identities = 36/143 (25%), Positives = 57/143 (39%), Gaps = 15/143 (10%)
Query: 54 PKKEKMKLRREQWLQKIEAIKLAEQKHREER-----------RRRATVVVGDLHPLRDAL 102
P++++ E+ L+K+E +L ++ EE+ RR+ + R
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 103 PELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQR--QQLL--EEERTRFQELLASPAYR 158
E + R Q RE + R +L R +R QQL +EE R Q+L R
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 159 ASPLVAIGQTLARQMQLEDGGQL 181
+ Q L R+ QL QL
Sbjct: 385 REQQLRREQQLRREQQLRREQQL 407
Score = 31.6 bits (70), Expect = 0.39
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 54 PKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL---PELLGLEA 110
P+K + + R +++ ++ E + EQ REER +R + +D L E L E
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 111 GSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEER--TRFQEL 151
+R+ + RE EL + + +QLL EER R QEL
Sbjct: 1038 REKRRLQERERQYREEEELQQ----EEEQLLGEERETRRRQEL 1076
Score = 30.8 bits (68), Expect = 0.66
Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 14/97 (14%)
Query: 55 KKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRR 114
++E+ + RREQ L++ + ++ +Q RE++ RR +L + R
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRRE--------------QQLRREQQLRRE 410
Query: 115 QTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQEL 151
Q RE R +L R +R + E+ R Q L
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Score = 30.4 bits (67), Expect = 0.87
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 44 RRGAEAKTVLPKKEKMKLRREQ----WLQKIEAIKLAEQKHREERRRRATVVVGDLHPLR 99
R+G E K ++ + ++ +E+ W ++ ++ E+K +EE +R +L
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR----ELQEEE 275
Query: 100 DALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRA 159
+ L +L E RQ ++ + R + R + ++ +EER QE R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 160 SPLVAIGQTLARQMQL 175
+ Q R+ QL
Sbjct: 336 EQQLRREQEERREQQL 351
Score = 30.4 bits (67), Expect = 0.87
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 26/123 (21%)
Query: 55 KKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRR 114
++E+ + RREQ L++ + + +Q RE+ R +
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEER------------------------REQ 362
Query: 115 QTRSRESNKPRPSELSRMSAAQRQQLL--EEERTRFQELLASPAYRASPLVAIGQTLARQ 172
Q R + + R +L R +R+Q L E++ R Q+L R + Q L R+
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 173 MQL 175
QL
Sbjct: 423 QQL 425
Score = 30.0 bits (66), Expect = 1.1
Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 31/148 (20%)
Query: 34 ELDVRS--VTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRR----- 86
E D R V S R E + ++E+ + RRE LQ E + Q+ EE+RR
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 87 --------RATVVVGDLHPLRDALPELLGLEAGS----------------RRQTRSRESN 122
R + PLR+ L E RRQ R RE
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 123 KPRPSELSRMSAAQRQQLLEEERTRFQE 150
E ++ +R Q L+EE QE
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Score = 28.9 bits (63), Expect = 2.5
Identities = 38/161 (23%), Positives = 61/161 (37%), Gaps = 42/161 (26%)
Query: 30 VQKLELDVRSVTSIRRGA---EAKTVLPKKEKMK------LRREQWLQKIEAIKLAEQKH 80
V++LE + R ++R E + L K E+ + LRREQ ++ + +K E++
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 81 R---------EERRRRATVVVGDLHPLRDALPELL----------------------GLE 109
R EE RR + + R+ + + +
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 110 AGSRRQTRSRESNKPRPSEL--SRMSAAQRQQLLEEERTRF 148
G RR+ E + R SEL A RQQ EE+R F
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Score = 28.1 bits (61), Expect = 4.3
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 17/108 (15%)
Query: 44 RRGAEAKTVLPKKEKMKLRREQWLQKIEA----IKLAEQKHREERRRRATVVVGDLHPLR 99
R+ E + L ++E+ + REQ L+ E ++ +Q HR++R+R+
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF----------- 1533
Query: 100 DALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTR 147
L E L R Q R ++ ++ E + QQL +ER R
Sbjct: 1534 --LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Score = 27.7 bits (60), Expect = 5.6
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGS-RRQTRS 118
+LR+EQ L + E +L ++ + RR+ + L+ +LL E RRQ R
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 119 RESNKPRPSELSRMSAAQRQQLLEE-ERTRFQE 150
R+ K + ++ + Q L EE E+ R QE
Sbjct: 958 RQYRKDK-----KLQQKEEQLLGEEPEKRRRQE 985
Score = 27.7 bits (60), Expect = 5.6
Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 23/130 (17%)
Query: 44 RRGAEAKTVLPKKEKMKLRREQWLQKI---------EAIKLAEQKHREERRRRATVVVGD 94
R+ E + +L ++E+ LRR++ +K + K E++ R R+ R + +
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 95 LHPLR----------DALPELLGLEAGSRRQTRSR----ESNKPRPSELSRMSAAQRQQL 140
LR D + E RQ R R E + R E R + QQL
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 141 LEEERTRFQE 150
+E +F+E
Sbjct: 1456 RQERHRKFRE 1465
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 14/136 (10%)
Query: 53 LPKKEKMKLRRE----QWLQKIEAIKLAEQKHREE----RRRRATVVVGDLHPLRDALPE 104
L ++E+ K RR+ Q+ ++ E + EQ REE RR+ + L+ +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 105 LLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQ---ELLASPAYRASP 161
LL E RRQ R R+ + EL R QR + E++R+ + E A R +
Sbjct: 1183 LLREEQEKRRQERERQYRE--EEELQRQKRKQRYR-DEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 162 LVAIGQTLARQMQLED 177
+ G+ + QLED
Sbjct: 1240 VYCKGRENEQFRQLED 1255
Score = 26.9 bits (58), Expect = 9.6
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATV 90
QK + R + +E + L ++++ + E W Q+ E + E++ EE+ +
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
Query: 91 VVGDLHPLRDAL--PELLGLEAGSR--RQTRSRESNKPRPSELSRMSAAQRQQLLEEERT 146
+ P + L ELL L R +Q + RE E +R+ +L +E
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 147 RFQE 150
+ QE
Sbjct: 259 KLQE 262
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 35.4 bits (80), Expect = 0.027
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 55 KKEKMKLRREQWLQKIEAIK-----LAEQKHREERRRRATVVVGDLHPLRDALPELLGLE 109
+K++ + RR +WLQ+ E + L ++K E+ R R L R+
Sbjct: 639 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ-------- 690
Query: 110 AGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 152
RR+ RE + + Q +QL E+ER R QE L
Sbjct: 691 --ERREQERREQERREQERREQERREQERQLAEQERRREQERL 731
Score = 33.1 bits (74), Expect = 0.13
Identities = 35/158 (22%), Positives = 74/158 (46%), Gaps = 22/158 (13%)
Query: 9 IIPPFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKK---------EKM 59
++ FI N R +DP +E + + + ++RR EA+ + +K E++
Sbjct: 515 VMKSFIKRNTPLR--MDPKCSF--VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV 570
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSR 119
KL+RE+ L+K+ + ++ +EE++++ + + E E ++++ ++
Sbjct: 571 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 630
Query: 120 -----ESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 152
E+ + + E R+ Q+ EEE R QELL
Sbjct: 631 KMEEVEARRKQEEEARRLRWLQQ----EEEERRHQELL 664
Score = 30.8 bits (68), Expect = 0.66
Identities = 25/108 (23%), Positives = 45/108 (41%)
Query: 43 IRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL 102
+R+ AEAK + ++E+ + +E+ Q+ + EQ+ RE+ R+ A A
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 103 PELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQE 150
EL E R Q + + +QL EE+ + +E
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 35.4 bits (80), Expect = 0.027
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 55 KKEKMKLRREQWLQKIEAIK-----LAEQKHREERRRRATVVVGDLHPLRDALPELLGLE 109
+K++ + RR +WLQ+ E + L ++K E+ R R L R+
Sbjct: 635 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ-------- 686
Query: 110 AGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 152
RR+ RE + + Q +QL E+ER R QE L
Sbjct: 687 --ERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
Score = 30.8 bits (68), Expect = 0.66
Identities = 25/108 (23%), Positives = 45/108 (41%)
Query: 43 IRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL 102
+R+ AEAK + ++E+ + +E+ Q+ + EQ+ RE+ R+ A A
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 103 PELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQE 150
EL E R Q + + +QL EE+ + +E
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 30.4 bits (67), Expect = 0.87
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 14/127 (11%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ 115
KEK + R E +K EA +L QK E++RRR V L E R+
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-------------KLKREERLRKV 577
Query: 116 TRSRESNKPRPSELSRMSAAQRQQLLEE-ERTRFQELLASPAYRASPLVAIGQTLARQMQ 174
++RE + E + + Q+ E+ E+ + + L A + + + + AR+ Q
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 175 LEDGGQL 181
E+ +L
Sbjct: 638 EEEARRL 644
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 34.7 bits (78), Expect = 0.046
Identities = 45/179 (25%), Positives = 85/179 (47%), Gaps = 13/179 (7%)
Query: 12 PFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKM---KLRREQW-L 67
P N+ + A+ + PS ++LE+ R + +R E + ++E+M +L RE+
Sbjct: 121 PRQNSQLPAQVQNGPSQ--EELEIQRRQLQEQQRQKELERERLERERMERERLERERLER 178
Query: 68 QKIEAIKLAEQ---KHREERRRRATVVVGDLHPLRDALP--ELLGLEAGSRRQTRSRESN 122
+++E +L ++ + R+ER R+ + + ++ L E L E R++ E
Sbjct: 179 ERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 123 KPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAI-GQTLARQMQLEDGGQ 180
+ E R +R+QL E ER R A+PA +PL ++ G + A + L+ Q
Sbjct: 239 ERERQERERQEQLEREQL-EWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 34.7 bits (78), Expect = 0.046
Identities = 45/179 (25%), Positives = 85/179 (47%), Gaps = 13/179 (7%)
Query: 12 PFINTNIFARTKIDPSALVQKLELDVRSVTSIRRGAEAKTVLPKKEKM---KLRREQW-L 67
P N+ + A+ + PS ++LE+ R + +R E + ++E+M +L RE+
Sbjct: 121 PRQNSQLPAQVQNGPSQ--EELEIQRRQLQEQQRQKELERERLERERMERERLERERLER 178
Query: 68 QKIEAIKLAEQ---KHREERRRRATVVVGDLHPLRDALP--ELLGLEAGSRRQTRSRESN 122
+++E +L ++ + R+ER R+ + + ++ L E L E R++ E
Sbjct: 179 ERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 123 KPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAI-GQTLARQMQLEDGGQ 180
+ E R +R+QL E ER R A+PA +PL ++ G + A + L+ Q
Sbjct: 239 ERERQERERQEQLEREQL-EWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 28 ALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRR 87
AL Q +L+ + + + K+E+ + +R++ L++ + L Q+ E +RR
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 88 ATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTR 147
+ +AL E RRQ R E + + L R+ +R+ EEER +
Sbjct: 776 EEELA--RRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRRE---EEERRK 829
Query: 148 FQELL 152
+ELL
Sbjct: 830 QEELL 834
Score = 32.3 bits (72), Expect = 0.23
Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL------AEQKHREER 84
++ EL+V+ + R + + ++ +L+++Q Q++ +KL +Q +
Sbjct: 877 KRKELEVQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 85 RRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEE 144
+ +AT+ + ++ L + R+ + RE + + EL M A Q+QQ +++
Sbjct: 933 QSQATLSLAEIQKLEE------------ERERQLREEQRRQQREL--MKALQQQQQQQQQ 978
Query: 145 RTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
+ ++ P+ L+ I Q ARQMQ + Q
Sbjct: 979 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 28 ALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRR 87
AL Q +L+ + + + K+E+ + +R++ L++ + L Q+ E +RR
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 88 ATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTR 147
+ +AL E RRQ R E + + L R+ +R+ EEER +
Sbjct: 803 EEELA--RRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRRE---EEERRK 856
Query: 148 FQELL 152
+ELL
Sbjct: 857 QEELL 861
Score = 32.3 bits (72), Expect = 0.23
Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL------AEQKHREER 84
++ EL+V+ + R + + ++ +L+++Q Q++ +KL +Q +
Sbjct: 904 KRKELEVQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 85 RRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEE 144
+ +AT+ + ++ L + R+ + RE + + EL M A Q+QQ +++
Sbjct: 960 QSQATLSLAEIQKLEE------------ERERQLREEQRRQQREL--MKALQQQQQQQQQ 1005
Query: 145 RTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
+ ++ P+ L+ I Q ARQMQ + Q
Sbjct: 1006 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 28 ALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRR 87
AL Q +L+ + + + K+E+ + +R++ L++ + L Q+ E +RR
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 88 ATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTR 147
+ +AL E RRQ R E + + L R+ +R+ EEER +
Sbjct: 782 EEELA--RRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRRE---EEERRK 835
Query: 148 FQELL 152
+ELL
Sbjct: 836 QEELL 840
Score = 32.3 bits (72), Expect = 0.23
Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL------AEQKHREER 84
++ EL+V+ + R + + ++ +L+++Q Q++ +KL +Q +
Sbjct: 883 KRKELEVQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 85 RRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEE 144
+ +AT+ + ++ L + R+ + RE + + EL M A Q+QQ +++
Sbjct: 939 QSQATLSLAEIQKLEE------------ERERQLREEQRRQQREL--MKALQQQQQQQQQ 984
Query: 145 RTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
+ ++ P+ L+ I Q ARQMQ + Q
Sbjct: 985 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 28 ALVQKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRR 87
AL Q +L+ + + + K+E+ + +R++ L++ + L Q+ E +RR
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 88 ATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTR 147
+ +AL E RRQ R E + + L R+ +R+ EEER +
Sbjct: 782 EEELA--RRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRRE---EEERRK 835
Query: 148 FQELL 152
+ELL
Sbjct: 836 QEELL 840
Score = 32.3 bits (72), Expect = 0.23
Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 31 QKLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL------AEQKHREER 84
++ EL+V+ + R + + ++ +L+++Q Q++ +KL +Q +
Sbjct: 883 KRKELEVQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 85 RRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEE 144
+ +AT+ + ++ L + R+ + RE + + EL M A Q+QQ +++
Sbjct: 939 QSQATLSLAEIQKLEE------------ERERQLREEQRRQQREL--MKALQQQQQQQQQ 984
Query: 145 RTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQ 180
+ ++ P+ L+ I Q ARQMQ + Q
Sbjct: 985 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 34.7 bits (78), Expect = 0.046
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 58 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTR 117
K KLR EQ ++ +E E+K R + R + GDL ++++ + ++ + +
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD------AAQDKQQ 1124
Query: 118 SRESNKPRPSELSRMS---------AAQRQQLLEEERTRFQEL 151
E K + SELS++S AQ Q+ ++E + R +EL
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEEL 1167
Score = 32.7 bits (73), Expect = 0.17
Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 15/127 (11%)
Query: 25 DPSALVQKLELDVRSVTSIRRGAEAKTVL-----PKKEKMKLRREQWLQKIEAIKLAEQK 79
D L +KL+ ++ + E + +L K ++++ R E+ +++EA + A +
Sbjct: 1121 DKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARAR 1180
Query: 80 HREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQ 139
++R A +L L + L E G AG R R RE +EL R+ +
Sbjct: 1181 VEKQRAEAAR----ELEELSERLEEAGGASAGQREGCRKRE------AELGRLRRELEEA 1230
Query: 140 LLEEERT 146
L E T
Sbjct: 1231 ALRHEAT 1237
>gi|56118254 zinc finger protein 18 [Homo sapiens]
Length = 549
Score = 33.5 bits (75), Expect = 0.10
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 6/111 (5%)
Query: 46 GAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPEL 105
G EA T++ + R QW+ +I++ Q E+ + VG++ P + +P+
Sbjct: 109 GEEAVTLVESLKGDPQRLWQWI----SIQVLGQDILSEKMESPSCQVGEVEPHLEVVPQE 164
Query: 106 LGLEAGSR--RQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLAS 154
LGLE S + S + +E AA + LEE R Q+L AS
Sbjct: 165 LGLENSSSGPGELLSHIVKEESDTEAELALAASQPARLEERLIRDQDLGAS 215
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2375 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2435 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2491
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2510 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2560
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2598
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1710 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2313 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2431 VQTLEIQRQQSD 2442
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2379 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2438
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2439 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2495
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2496 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2514 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2564
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2565 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2602
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1654 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1713
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1714 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1759
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2317 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2375 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2434
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2435 VQTLEIQRQQSD 2446
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2375 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2434
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2435 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2491
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2510 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2560
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2598
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1710 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2313 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2431 VQTLEIQRQQSD 2442
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2343 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2402
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2403 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2459
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2460 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2478 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2528
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2529 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2566
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1618 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1677
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1678 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1723
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2281 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2339 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2398
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2399 VQTLEIQRQQSD 2410
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2512 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2571
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2572 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2628
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2629 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2647 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2697
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2698 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2735
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1787 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1846
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1847 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1892
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2450 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2507
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2508 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2567
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2568 VQTLEIQRQQSD 2579
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2353 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2412
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2413 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2469
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2470 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2488 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2538
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2539 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2576
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1628 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1687
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1688 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1733
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2291 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2348
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2349 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2408
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2409 VQTLEIQRQQSD 2420
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2361 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2420
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2421 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2477
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2478 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2496 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2546
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2547 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2584
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1636 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1695
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1696 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1741
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2299 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2356
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2357 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2416
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2417 VQTLEIQRQQSD 2428
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 32.7 bits (73), Expect = 0.17
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 22/173 (12%)
Query: 23 KIDPSALVQKLELDVRSVTSIRRGAE---------AKTVLPKKEKMKLRREQWLQKIEAI 73
+++ SA ++L+L V ++ + AE A+ + K + +L ++ + ++ +
Sbjct: 2402 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2461
Query: 74 KLAEQK--HREERRRRATVVVGDLHPLRDALPE---LLGLEAGSRRQTRS----RESNKP 124
++ Q+ H ER R A + +L ++ L + LL L++ + + +E+
Sbjct: 2462 EIQRQQSDHDAERLREA---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2518
Query: 125 RPSELSRM-SAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 176
+ S LS S QR++ +E+E+ + ++L +A L Q +QM+ E
Sbjct: 2519 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571
Score = 32.7 bits (73), Expect = 0.17
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 57 EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQT 116
E+ K + EQ Q + + A+Q E++R++ + R L + +E RRQ
Sbjct: 2537 EQEKAKLEQLFQ--DEVAKAQQLREEQQRQQQ-----QMEQERQRL--VASMEEARRRQH 2587
Query: 117 RSRESNKPRPSELSRMSAAQRQQ--LLEEERTRFQELL 152
+ E + + EL ++ +RQQ LL EE R +E L
Sbjct: 2588 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2625
Score = 29.6 bits (65), Expect = 1.5
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 60 KLRREQWLQKIEAIKLAEQKHREERRRRATV--VVGDLHPLRDALPELLGLEAGSRRQTR 117
++ +++ L + EA K E+ RE RRR V L + L G+ +Q
Sbjct: 1677 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1736
Query: 118 SRESNKPRPSELSRMSAA-----QRQQLLEEERTRFQELLASPAYRASPLVA 164
+ E EL R+ A Q++QLLEEE R Q A+ + L A
Sbjct: 1737 AAEQ------ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1782
Score = 27.3 bits (59), Expect = 7.3
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 56 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPE-----LLGLEA 110
KEKM+ +E K EA L +QK E + +A + D + L E LEA
Sbjct: 2340 KEKMQAVQEATRLKAEAELLQQQK--ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2397
Query: 111 GSRRQ---TRSRESNKPRPSELSRMSAAQRQ--QLLEEERTRFQELLASPAYRASPLVAI 165
+RQ + E K R +E+SR A + Q ++ E L V +
Sbjct: 2398 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2457
Query: 166 GQTLARQMQLED 177
QTL Q Q D
Sbjct: 2458 VQTLEIQRQQSD 2469
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 32.7 bits (73), Expect = 0.17
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 38 RSVTSIRRGAEAKTVLPKK-EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLH 96
R V ++ +A T L ++ + +K ++ Q E E RRR +G+L
Sbjct: 271 REVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRR-----LGELR 325
Query: 97 PLRDALPELLGLEAGSRRQTRSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 152
LR + +L AG +TR E R L AQR+Q+ E + R +E +
Sbjct: 326 ELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAM 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,461,388
Number of Sequences: 37866
Number of extensions: 264117
Number of successful extensions: 2146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 1803
Number of HSP's gapped (non-prelim): 418
length of query: 181
length of database: 18,247,518
effective HSP length: 96
effective length of query: 85
effective length of database: 14,612,382
effective search space: 1242052470
effective search space used: 1242052470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.