Guide to the Human Genome
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Search of human proteins with 19923879

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923879 Josephin domain containing 2 [Homo sapiens]
         (188 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923879 Josephin domain containing 2 [Homo sapiens]               376   e-105
gi|7661888 Josephin domain containing 1 [Homo sapiens]                200   5e-52
gi|189163493 ataxin 3 isoform 3 [Homo sapiens]                         52   3e-07
gi|13518019 ataxin 3 isoform 1 [Homo sapiens]                          52   3e-07
gi|209862748 ataxin 3-like [Homo sapiens]                              52   4e-07
gi|189163495 ataxin 3 isoform 4 [Homo sapiens]                         39   0.002
gi|13518013 ataxin 3 isoform 2 [Homo sapiens]                          31   0.72 
gi|40786404 coiled-coil domain containing 23 [Homo sapiens]            28   3.6  
gi|190684671 mitogen-activated protein kinase binding protein 1 ...    27   7.9  
gi|190684677 mitogen-activated protein kinase binding protein 1 ...    27   7.9  

>gi|19923879 Josephin domain containing 2 [Homo sapiens]
          Length = 188

 Score =  376 bits (966), Expect = e-105
 Identities = 188/188 (100%), Positives = 188/188 (100%)

Query: 1   MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHR 60
           MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHR
Sbjct: 1   MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHR 60

Query: 61  SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLP 120
           SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLP
Sbjct: 61  SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLP 120

Query: 121 LRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEE 180
           LRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEE
Sbjct: 121 LRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEE 180

Query: 181 KGSWLRTD 188
           KGSWLRTD
Sbjct: 181 KGSWLRTD 188


>gi|7661888 Josephin domain containing 1 [Homo sapiens]
          Length = 202

 Score =  200 bits (509), Expect = 5e-52
 Identities = 101/183 (55%), Positives = 131/183 (71%), Gaps = 3/183 (1%)

Query: 8   QPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEICKRLAPDSRLNPHR-SLLGT 65
           Q +PP +YHE+QR ELCA+HALNNV Q    F+++   EI +RL+P++ + PH+ S+LG 
Sbjct: 20  QAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGN 79

Query: 66  GNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRH 125
           GNYDVNVIMAALQ  G  AVWWD+RR +  +AL  V+G I+NLPS +  G L LPL+R+H
Sbjct: 80  GNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWGPLKLPLKRQH 139

Query: 126 WVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWL 185
           W+ +R+V G YYNLDSKL+ PE +G E  +R FL   L    CE+LLVV +EVE   SW 
Sbjct: 140 WICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVEAHQSW- 198

Query: 186 RTD 188
           RTD
Sbjct: 199 RTD 201


>gi|189163493 ataxin 3 isoform 3 [Homo sapiens]
          Length = 346

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 20/155 (12%)

Query: 13  TVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYD--V 70
           +++HE+Q   LCA H LNN+LQ + FS      I  +L  + R+      + + +Y   +
Sbjct: 3   SIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFL 62

Query: 71  NVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALR 130
            VI  AL+  GL  + ++          P+   L ++  +  S     +   + HW  +R
Sbjct: 63  QVISNALKVWGLELILFNS---------PEYQRLRIDPINERSF----ICNYKEHWFTVR 109

Query: 131 QVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQ 165
           ++   ++NL+S L  PE + D      +LA  LAQ
Sbjct: 110 KLGKQWFNLNSLLTGPELISD-----TYLALFLAQ 139


>gi|13518019 ataxin 3 isoform 1 [Homo sapiens]
          Length = 361

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 35/170 (20%)

Query: 13  TVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRL---------------- 56
           +++HE+Q   LCA H LNN+LQ + FS      I  +L  + R+                
Sbjct: 3   SIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFL 62

Query: 57  -NPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLG 115
             P  ++  +G + + VI  AL+  GL  + ++          P+   L ++  +  S  
Sbjct: 63  QQPSGNMDDSGFFSIQVISNALKVWGLELILFNS---------PEYQRLRIDPINERSF- 112

Query: 116 LLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQ 165
              +   + HW  +R++   ++NL+S L  PE + D      +LA  LAQ
Sbjct: 113 ---ICNYKEHWFTVRKLGKQWFNLNSLLTGPELISD-----TYLALFLAQ 154


>gi|209862748 ataxin 3-like [Homo sapiens]
          Length = 355

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 42/161 (26%)

Query: 14  VYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRL----------------- 56
           ++HE+Q   LCA H LNN+LQ + FS      I  +L  + R+                 
Sbjct: 4   IFHEKQEGFLCAQHCLNNLLQGEYFSPVELASIAHQLDEEERMRMAEGGVTSEEYLAFLQ 63

Query: 57  NPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGL 116
            P  ++  TG + + VI  AL+  GL  + +                   N P    LG+
Sbjct: 64  QPSENMDDTGFFSIQVISNALKFWGLEIIHF-------------------NNPEYQKLGI 104

Query: 117 LSLPLR------RRHWVALRQVDGVYYNLDSKLRAPEALGD 151
             +  R      ++HW  +R+    ++NL+S L  PE + D
Sbjct: 105 DPINERSFICNYKQHWFTIRKFGKHWFNLNSLLAGPELISD 145


>gi|189163495 ataxin 3 isoform 4 [Homo sapiens]
          Length = 295

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 17/44 (38%), Positives = 26/44 (59%)

Query: 13 TVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRL 56
          +++HE+Q   LCA H LNN+LQ + FS      I  +L  + R+
Sbjct: 3  SIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERM 46


>gi|13518013 ataxin 3 isoform 2 [Homo sapiens]
          Length = 306

 Score = 30.8 bits (68), Expect = 0.72
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 5/43 (11%)

Query: 123 RRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQ 165
           + HW  +R++   ++NL+S L  PE + D      +LA  LAQ
Sbjct: 62  KEHWFTVRKLGKQWFNLNSLLTGPELISD-----TYLALFLAQ 99


>gi|40786404 coiled-coil domain containing 23 [Homo sapiens]
          Length = 66

 Score = 28.5 bits (62), Expect = 3.6
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 5/45 (11%)

Query: 8  QPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAP 52
          Q S      +RQR E+ A++ +   L+QQ F     DE CK++ P
Sbjct: 24 QKSAQQELKQRQRAEIYALNRVMTELEQQQF-----DEFCKQMQP 63


>gi|190684671 mitogen-activated protein kinase binding protein 1
            isoform a [Homo sapiens]
          Length = 1508

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 12/24 (50%), Positives = 17/24 (70%)

Query: 89   RRRPLSQLALPQVLGLILNLPSPV 112
            R  PLS+LALP    L+L++P P+
Sbjct: 1275 RVSPLSKLALPSRAHLVLDIPKPL 1298


>gi|190684677 mitogen-activated protein kinase binding protein 1
            isoform b [Homo sapiens]
          Length = 1514

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 12/24 (50%), Positives = 17/24 (70%)

Query: 89   RRRPLSQLALPQVLGLILNLPSPV 112
            R  PLS+LALP    L+L++P P+
Sbjct: 1281 RVSPLSKLALPSRAHLVLDIPKPL 1304


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,741,014
Number of Sequences: 37866
Number of extensions: 326693
Number of successful extensions: 755
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 741
Number of HSP's gapped (non-prelim): 10
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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