BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|195972890 unc-84 homolog A isoform a [Homo sapiens] (785 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|195972890 unc-84 homolog A isoform a [Homo sapiens] 1576 0.0 gi|110227866 unc-84 homolog A isoform b [Homo sapiens] 1387 0.0 gi|31742498 unc-84 homolog B [Homo sapiens] 358 1e-98 gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens] 186 6e-47 gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens] 186 6e-47 gi|21361792 sperm associated antigen 4-like [Homo sapiens] 150 4e-36 gi|11037055 sperm associated antigen 4 [Homo sapiens] 144 2e-34 gi|110611218 ribosome binding protein 1 [Homo sapiens] 42 0.003 gi|110611220 ribosome binding protein 1 [Homo sapiens] 42 0.003 gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 41 0.004 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 41 0.005 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 40 0.006 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.006 gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 40 0.008 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 40 0.011 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 39 0.014 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.019 gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 39 0.024 gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 39 0.024 gi|154090997 coiled-coil domain containing 13 [Homo sapiens] 39 0.024 gi|170784854 PTPRF interacting protein, binding protein 2 (lipri... 38 0.032 gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 38 0.032 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 38 0.042 gi|4504063 golgin 97 [Homo sapiens] 38 0.042 gi|118498356 kinectin 1 isoform a [Homo sapiens] 37 0.054 gi|33620775 kinectin 1 isoform a [Homo sapiens] 37 0.054 gi|238908495 similar to pleckstrin homology domain protein (5V32... 37 0.071 gi|21493045 A-kinase anchor protein 6 [Homo sapiens] 37 0.071 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.093 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.093 >gi|195972890 unc-84 homolog A isoform a [Homo sapiens] Length = 785 Score = 1576 bits (4081), Expect = 0.0 Identities = 785/785 (100%), Positives = 785/785 (100%) Query: 1 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT 60 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT Sbjct: 1 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT 60 Query: 61 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG 120 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG Sbjct: 61 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG 120 Query: 121 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH 180 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH Sbjct: 121 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH 180 Query: 181 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRT 240 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRT Sbjct: 181 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRT 240 Query: 241 AWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLF 300 AWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLF Sbjct: 241 AWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLF 300 Query: 301 LLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWH 360 LLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWH Sbjct: 301 LLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWH 360 Query: 361 WMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPR 420 WMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPR Sbjct: 361 WMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPR 420 Query: 421 ETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQL 480 ETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQL Sbjct: 421 ETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQL 480 Query: 481 ELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ 540 ELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ Sbjct: 481 ELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ 540 Query: 541 FVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVN 600 FVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVN Sbjct: 541 FVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVN 600 Query: 601 SALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQ 660 SALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQ Sbjct: 601 SALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQ 660 Query: 661 PDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLEN 720 PDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLEN Sbjct: 661 PDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLEN 720 Query: 721 EYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVH 780 EYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVH Sbjct: 721 EYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVH 780 Query: 781 GEPVK 785 GEPVK Sbjct: 781 GEPVK 785 >gi|110227866 unc-84 homolog A isoform b [Homo sapiens] Length = 702 Score = 1387 bits (3590), Expect = 0.0 Identities = 702/735 (95%), Positives = 702/735 (95%), Gaps = 33/735 (4%) Query: 51 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 110 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ Sbjct: 1 MSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQ 60 Query: 111 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 170 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG Sbjct: 61 VTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG 120 Query: 171 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRI 230 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK Sbjct: 121 DVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK----------- 169 Query: 231 GAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC 290 W KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC Sbjct: 170 -----------W-----------KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNIC 207 Query: 291 KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL 350 KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL Sbjct: 208 KFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPL 267 Query: 351 QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS 410 QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS Sbjct: 268 QGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSAS 327 Query: 411 VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ 470 VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ Sbjct: 328 VRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQ 387 Query: 471 LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL 530 LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL Sbjct: 388 LLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSL 447 Query: 531 EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI 590 EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI Sbjct: 448 EQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGI 507 Query: 591 TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY 650 TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY Sbjct: 508 TEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWY 567 Query: 651 FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP 710 FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP Sbjct: 568 FSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAP 627 Query: 711 KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE 770 KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE Sbjct: 628 KDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPE 687 Query: 771 YTCLYRFRVHGEPVK 785 YTCLYRFRVHGEPVK Sbjct: 688 YTCLYRFRVHGEPVK 702 >gi|31742498 unc-84 homolog B [Homo sapiens] Length = 717 Score = 358 bits (919), Expect = 1e-98 Identities = 269/776 (34%), Positives = 386/776 (49%), Gaps = 104/776 (13%) Query: 51 MSRRSLRLATTACTLGDGEAVGADSGTSSAVS----LKNRAARTTKQRRSTNKSAFSINH 106 MSRRS RL T + GD + + G+S A S K+ RT K R+S+N S Sbjct: 1 MSRRSQRL--TRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSSNMKRLS--- 54 Query: 107 VSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAI 166 + Q+ S +H S ++ ESW +++++ GD G + Sbjct: 55 PAPQLGPSSDAHTSYYS--------ESLVHESWFPPRSSLEEL-----HGDANWGEDLRV 101 Query: 167 QGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQI 226 + G G S S L RK ++ G YS + + Y + Sbjct: 102 RRRRGTG--------GSESSRASGLVGRKATEDFLGSSSG-----YSSEDDYVGYSDVDQ 148 Query: 227 LRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCL 286 + AVSR A S LW+ +PG+ ++WW G WY+ T S L+VF+LTR Sbjct: 149 QSSSSRLRSAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRF 207 Query: 287 RNICKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFK 340 ++ FL L+PL LL G F+ +F P L +W + ++R D+ + Sbjct: 208 SSLKTFLWFLLPLLLLTC--LTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE--- 262 Query: 341 PTTSRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQ 399 +R P Q + MS V L N ++ L++L+ R Sbjct: 263 ---ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGA 314 Query: 400 M-EGGAAGPS-----------ASVRDAVGQPP--RETDFMAFHQEHEVRMSHL---EDIL 442 +GG G S S R+A + RET + +R H ED+ Sbjct: 315 PGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLF 374 Query: 443 GKLREKSEAIQKELEQTKQK----TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTG 498 K+ S+ + ++Q K + T + E + + L+ +L L+ EL++ ++ Sbjct: 375 KKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSS 434 Query: 499 C--------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTM 550 + + AV++ V+ Q + + GG LLQR ++Q Sbjct: 435 VAEEVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQR--------EEMQAQ 484 Query: 551 LRDLQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYS 607 LR+L+ +IL HV+ + EA S + + G G+TE Q IV AL+ YS Sbjct: 485 LRELESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 540 Query: 608 QDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGN 667 +D+ G+ D+ALESGG S++STRCSETYETKTAL+SLFGIPLWY SQSPRV++QPD++PGN Sbjct: 541 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 600 Query: 668 CWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQ 727 CWAF+G QG+ VVRLS I P A TLEH+PK LSP ISSAPKDFA++G + + Q+EG Sbjct: 601 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 660 Query: 728 LLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEP 783 LLG+FTYDQDGE +Q F + P +Q+VELRI +NWGHPEYTC+YRFRVHGEP Sbjct: 661 LLGKFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEP 715 >gi|71834870 Sad1 and UNC84 domain containing 1 [Homo sapiens] Length = 357 Score = 186 bits (473), Expect = 6e-47 Identities = 89/188 (47%), Positives = 124/188 (65%), Gaps = 1/188 (0%) Query: 598 IVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRV 657 +VN LK +D+ M D+AL+S G SI+ SE+Y+ A + GI P + Sbjct: 169 LVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDI 228 Query: 658 VIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYG 717 ++QPD+YPG CWAF GSQG+ +++L+ I P A T+EHI + +SP+GNISSAPK+F+VYG Sbjct: 229 ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYG 288 Query: 718 LENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRF 777 + + + E LGQF Y++ G ++Q F+ L+ V+L IFSNWGHP+YTCLYRF Sbjct: 289 ITKKCEGEEIFLGQFIYNKTGTTVQTFE-LQHAVSEYLLCVKLNIFSNWGHPKYTCLYRF 347 Query: 778 RVHGEPVK 785 RVHG P K Sbjct: 348 RVHGTPGK 355 >gi|71834868 Sad1 and UNC84 domain containing 1 [Homo sapiens] Length = 357 Score = 186 bits (473), Expect = 6e-47 Identities = 89/188 (47%), Positives = 124/188 (65%), Gaps = 1/188 (0%) Query: 598 IVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRV 657 +VN LK +D+ M D+AL+S G SI+ SE+Y+ A + GI P + Sbjct: 169 LVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDI 228 Query: 658 VIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYG 717 ++QPD+YPG CWAF GSQG+ +++L+ I P A T+EHI + +SP+GNISSAPK+F+VYG Sbjct: 229 ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYG 288 Query: 718 LENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRF 777 + + + E LGQF Y++ G ++Q F+ L+ V+L IFSNWGHP+YTCLYRF Sbjct: 289 ITKKCEGEEIFLGQFIYNKTGTTVQTFE-LQHAVSEYLLCVKLNIFSNWGHPKYTCLYRF 347 Query: 778 RVHGEPVK 785 RVHG P K Sbjct: 348 RVHGTPGK 355 >gi|21361792 sperm associated antigen 4-like [Homo sapiens] Length = 379 Score = 150 bits (379), Expect = 4e-36 Identities = 89/231 (38%), Positives = 133/231 (57%), Gaps = 12/231 (5%) Query: 556 LQILR----NVTHHVSVTKQLPTS-EAVVSAVSEAGASGITEAQARAIVNSALKLYSQDK 610 LQ LR V HH + L S +++ + E A + A+ I +K+ D Sbjct: 138 LQSLRLYQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKI----MKMIHGDY 193 Query: 611 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA 670 DFAL+S G SI S TY + A I LW ++Q P V+++P++ PGNCWA Sbjct: 194 IEKPDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWA 253 Query: 671 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG 730 F+G +G + ++L+ ++ + TL+HIPKT+S +G++ +APKDF +YG+E +EE LG Sbjct: 254 FEGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEE-VFLG 312 Query: 731 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHG 781 F + Q +QMF +P AF V+++I SNWG+P +TCLYR RVHG Sbjct: 313 AFQF-QPENIIQMFPLQNQP-ARAFSAVKVKISSNWGNPGFTCLYRVRVHG 361 >gi|11037055 sperm associated antigen 4 [Homo sapiens] Length = 437 Score = 144 bits (364), Expect = 2e-34 Identities = 71/194 (36%), Positives = 110/194 (56%), Gaps = 2/194 (1%) Query: 588 SGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIP 647 S + A + + + ++D D+AL S G SI + S Y + Sbjct: 231 STVRAANSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFS 290 Query: 648 LWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNIS 707 W +++ P V+++P ++PGNCWAF+G QG +V++L + + TL+H P ++ TG + Sbjct: 291 FWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGAN 350 Query: 708 SAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWG 767 SAP+DFAV+GL+ Y E LG+FT+D + +Q F L+ AF V+++I SNWG Sbjct: 351 SAPRDFAVFGLQ-VYDETEVSLGKFTFDVEKSEIQTFH-LQNDPPAAFPKVKIQILSNWG 408 Query: 768 HPEYTCLYRFRVHG 781 HP +TCLYR R HG Sbjct: 409 HPRFTCLYRVRAHG 422 >gi|110611218 ribosome binding protein 1 [Homo sapiens] Length = 977 Score = 41.6 bits (96), Expect = 0.003 Identities = 56/249 (22%), Positives = 110/249 (44%), Gaps = 35/249 (14%) Query: 366 EQQVASLSGQCH-HHGENLRELTTLLQKLQARVDQMEGGAAGPSASV-------RDAVGQ 417 EQ++ ++ + + E+++E+ L K++ +Q+E G A + RDA+ Q Sbjct: 319 EQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQ 378 Query: 418 PPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLL--- 472 + + + ++R L + +L EKSEA++++ +Q K + +A +Q+L Sbjct: 379 ATSQVESKQNAELAKLRQE-LSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ 437 Query: 473 ----PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGG 528 + E LQ LD++ EL H ++ ++ A E+ Q QQ Sbjct: 438 ASHRESEEALQKRLDEVSRELC---HTQSSHASLRADAEKAQEQ-----------QQQMA 483 Query: 529 SLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGAS 588 L LQ ++ SK + L L Q+ + +T+++ + EA++ A A Sbjct: 484 ELHSKLQSSEAEVRSKCE---ELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQ 540 Query: 589 GITEAQARA 597 + +QA A Sbjct: 541 DVQASQAEA 549 Score = 32.7 bits (73), Expect = 1.3 Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 53/210 (25%) Query: 299 LFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFP 358 L LL LS+ Q N+ +L L + P + S+L++ Sbjct: 634 LLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLRE---------- 683 Query: 359 WHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQP 418 E+ ++L +C + L E +L+ LQ V++ E R VG Sbjct: 684 ------AEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE-------QVWRAKVGAA 730 Query: 419 PRETDFMAFHQEHEVRMSHLEDILGKL----------REKSEAIQKELE----------Q 458 E Q+ V + HLE+I+ KL RE + ++ ELE Q Sbjct: 731 EEEL------QKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQ 784 Query: 459 TKQKTISAVGEQLLPTVEHLQLELDQLKSE 488 K ++ + + LL + Q +LD KSE Sbjct: 785 NYAKEVAGLRQLLLES----QSQLDAAKSE 810 >gi|110611220 ribosome binding protein 1 [Homo sapiens] Length = 977 Score = 41.6 bits (96), Expect = 0.003 Identities = 56/249 (22%), Positives = 110/249 (44%), Gaps = 35/249 (14%) Query: 366 EQQVASLSGQCH-HHGENLRELTTLLQKLQARVDQMEGGAAGPSASV-------RDAVGQ 417 EQ++ ++ + + E+++E+ L K++ +Q+E G A + RDA+ Q Sbjct: 319 EQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQ 378 Query: 418 PPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLL--- 472 + + + ++R L + +L EKSEA++++ +Q K + +A +Q+L Sbjct: 379 ATSQVESKQNAELAKLRQE-LSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ 437 Query: 473 ----PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGG 528 + E LQ LD++ EL H ++ ++ A E+ Q QQ Sbjct: 438 ASHRESEEALQKRLDEVSRELC---HTQSSHASLRADAEKAQEQ-----------QQQMA 483 Query: 529 SLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGAS 588 L LQ ++ SK + L L Q+ + +T+++ + EA++ A A Sbjct: 484 ELHSKLQSSEAEVRSKCE---ELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQ 540 Query: 589 GITEAQARA 597 + +QA A Sbjct: 541 DVQASQAEA 549 Score = 32.7 bits (73), Expect = 1.3 Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 53/210 (25%) Query: 299 LFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFP 358 L LL LS+ Q N+ +L L + P + S+L++ Sbjct: 634 LLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLRE---------- 683 Query: 359 WHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQP 418 E+ ++L +C + L E +L+ LQ V++ E R VG Sbjct: 684 ------AEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE-------QVWRAKVGAA 730 Query: 419 PRETDFMAFHQEHEVRMSHLEDILGKL----------REKSEAIQKELE----------Q 458 E Q+ V + HLE+I+ KL RE + ++ ELE Q Sbjct: 731 EEEL------QKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQ 784 Query: 459 TKQKTISAVGEQLLPTVEHLQLELDQLKSE 488 K ++ + + LL + Q +LD KSE Sbjct: 785 NYAKEVAGLRQLLLES----QSQLDAAKSE 810 >gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] Length = 1194 Score = 41.2 bits (95), Expect = 0.004 Identities = 39/144 (27%), Positives = 71/144 (49%), Gaps = 7/144 (4%) Query: 345 RLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGA 404 +L+Q LQ +E P + + Q+VA+L+ HG L L +L+ + +++ Sbjct: 360 KLQQTLQ-KAETLP-EIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQ--R 415 Query: 405 AGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QK 462 A + D + ET + +E HL++ +G L EK+ ++ +E+ K Q Sbjct: 416 ARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKN-SLSEEIANMKKLQD 474 Query: 463 TISAVGEQLLPTVEHLQLELDQLK 486 + EQLL +E +Q+E+DQL+ Sbjct: 475 ELLLNKEQLLAEMERMQMEIDQLR 498 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 40.8 bits (94), Expect = 0.005 Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 23/223 (10%) Query: 345 RLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQ----- 399 RLK+ Q SE + EQQVA L + E L+E T +LQ ++D+ Sbjct: 436 RLKEQRQLSSEK-----LMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490 Query: 400 MEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQT 459 E A S + + Q E + + ++ +LE +L K +E ++KE E Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQ-KIQNLEALLQKSKENISLLEKEREDL 549 Query: 460 KQKTISAVGE-----QLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVR 514 K + GE QL LQ ++ QL +L K E+ QE + QV+ Sbjct: 550 YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKL------KNQSESHKQAQENLHDQVQ 603 Query: 515 EMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQ 557 E L + + SLE + +SQ + + L D+Q++ Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQL-DIQIK 645 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 40.4 bits (93), Expect = 0.006 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 18/199 (9%) Query: 377 HHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMS 436 H E L L+ KL+ +VD++EG + + + + + ++E M Sbjct: 1023 HMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRE---SME 1079 Query: 437 HLEDILGKLREKSEAIQKELEQTKQKTISAVG--EQLLPTVEHLQLELDQLKSELSSWR- 493 +LE L E+ + EL Q K + G QL TV+ LQ ++ LK +L + R Sbjct: 1080 NLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERT 1139 Query: 494 -HVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLR 552 K E D Q+ D+ R E+ G SL QL + + +K Q + R Sbjct: 1140 TRAKMERERADLTQDLADLNER-------LEEVGGSSLAQL--EITKKQETK--FQKLHR 1188 Query: 553 DLQLQILRNVTHHVSVTKQ 571 D++ L T S+ K+ Sbjct: 1189 DMEEATLHFETTSASLKKR 1207 Score = 37.7 bits (86), Expect = 0.042 Identities = 35/161 (21%), Positives = 76/161 (47%), Gaps = 15/161 (9%) Query: 429 QEHEVRMSHLEDILGKLREKSEAIQKELEQTK------QKTISAVGEQLLPTVEHLQLEL 482 +E ++ +E + + E+ +Q LE+T+ + I +LL L+ +L Sbjct: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588 Query: 483 DQLKSELSSWRHVKTGCETVDAVQERVDVQVR---EMVKLLFSEDQQGGSLEQLL----Q 535 + E+ ++R K C T+D++Q +D + + E+ +L ++ +E L + Sbjct: 1589 SEKDEEIENFRR-KQQC-TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANR 1646 Query: 536 RFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSE 576 + S S G LQ ++DLQ+Q+ + + + +Q+ +E Sbjct: 1647 QVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAE 1687 Score = 34.3 bits (77), Expect = 0.46 Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 7/123 (5%) Query: 385 ELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGK 444 +LT L L R++++ G + + +ET F H++ E H E Sbjct: 1150 DLTQDLADLNERLEEVGGSSLAQLEITKK------QETKFQKLHRDMEEATLHFETTSAS 1203 Query: 445 LREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDA 504 L+++ ELE + + + V ++L LQLE+D L + + K E + Sbjct: 1204 LKKRHADSLAELE-GQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCT 1262 Query: 505 VQE 507 + E Sbjct: 1263 LYE 1265 Score = 33.5 bits (75), Expect = 0.78 Identities = 39/171 (22%), Positives = 86/171 (50%), Gaps = 8/171 (4%) Query: 433 VRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSW 492 V+ S + + + L+E+ +QK LE+++ + +Q+ T E L L QL++E + Sbjct: 852 VKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL-QLQAEQETL 910 Query: 493 RHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ-FVSK---GDLQ 548 +V+ CE + + +++ +V+E+ + + E++ L ++ + F K DL+ Sbjct: 911 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970 Query: 549 TMLRDLQLQILRNVTHHV-SVTKQLPTSEAVVSAVSEAGASGITEAQARAI 598 TML + + R H V ++T+++ +S ++ A A + EA + + Sbjct: 971 TMLVKSEKE-KRTTEHKVKNLTEEVEFLNEDISKLNRA-AKVVQEAHQQTL 1019 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 40.4 bits (93), Expect = 0.006 Identities = 63/265 (23%), Positives = 111/265 (41%), Gaps = 60/265 (22%) Query: 329 TQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELT- 387 T+ + D ++ + L+ D E +SG+++ + ++ GQ R+L Sbjct: 589 TEEIKDLEEQLTEGQIAANEALKKDLEGV----ISGLQEYLGTIKGQATQAQNECRKLRD 644 Query: 388 ---TLLQKL---QARVDQMEGGAAGPS------ASVRDAVGQPPR--------ETDFMAF 427 TLLQ+L + DQ+E A A + A+ + + D A+ Sbjct: 645 EKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAY 704 Query: 428 HQEHEVRMSHLEDILGKLREKSE-----------AIQKELEQTKQKTISAVGE------- 469 E E R++ + +L+E+ E A+Q ELE+ +Q +A+G+ Sbjct: 705 EAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEK 764 Query: 470 -----QLLPTVEHLQLELDQLKSELSSWR----HVKTGCETVDAVQERVDVQVREMVKLL 520 +L ++HLQ + + LK +L ++ HV G + V RVD ++R +KL Sbjct: 765 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRRKLKLG 823 Query: 521 FSE-------DQQGGSLEQLLQRFS 538 E D G SL L ++FS Sbjct: 824 TGEMNIHSPSDVLGKSLADLQKQFS 848 >gi|21450705 leucine rich repeat containing 45 [Homo sapiens] Length = 670 Score = 40.0 bits (92), Expect = 0.008 Identities = 57/250 (22%), Positives = 109/250 (43%), Gaps = 32/250 (12%) Query: 368 QVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAF 427 ++ + H E+ + + +Q+L+A +E + A+ GQ E A Sbjct: 433 RIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEEL-IKAK 491 Query: 428 HQ---EHEVRMSHLED---ILGKLREKSEAI---QKELEQTKQKTISAVGEQLLPTVEHL 478 Q E + R++HLED +L + R++++ QK++ Q +S +G Q VE L Sbjct: 492 SQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQ----VEGL 547 Query: 479 QLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFS 538 + L++L+ ELS + A RV V+++E L +E +L + Sbjct: 548 RRRLEELQQELSLKDQERV------AEVSRVRVELQEQNGRLQAELAAQEALREKAAALE 601 Query: 539 SQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAI 598 Q L+ M D + +L + + S+ ++L EA ++ + + EAQ + Sbjct: 602 RQ------LKVMASDHREALLDRESENASLREKLRLREAEIARIRD------EEAQRASF 649 Query: 599 VNSALKLYSQ 608 + +A+ Y Q Sbjct: 650 LQNAVLAYVQ 659 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 39.7 bits (91), Expect = 0.011 Identities = 38/185 (20%), Positives = 81/185 (43%), Gaps = 11/185 (5%) Query: 366 EQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFM 425 E QV GQ +RE +++ + +V + EG VR+ GQ + M Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201 Query: 426 AFHQ----EHEVRMSHLEDILG----KLREKSEAI--QKELEQTKQKTISAVGEQLLPTV 475 + E E +M E+ +G ++R++ E + Q+E Q +++ + EQ+ Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261 Query: 476 EHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQ 535 E ++ + +Q++ + K E + E+ + Q+RE + + +++Q E+ ++ Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ-EEQMREQEEQMREQEEQMREQEEQMR 320 Query: 536 RFSSQ 540 Q Sbjct: 321 EQEEQ 325 Score = 34.7 bits (78), Expect = 0.35 Identities = 44/231 (19%), Positives = 93/231 (40%), Gaps = 17/231 (7%) Query: 330 QRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTL 389 Q V+ + + LK+ L+ D P E QV GQ +RE Sbjct: 21 QLVETEKSEIQLHIKELKRKLETDKIPLPQ------EGQVREQEGQVREQEGQVREQEGQ 74 Query: 390 LQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKS 449 +++ + +V + EG VR+ GQ RE + QE +VR G++RE+ Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE-----GQVREQE 128 Query: 450 EAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQE 507 ++++ Q +++ + Q+ ++ + Q++ + R + + Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188 Query: 508 RVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQI 558 + Q+ E + +++Q G E+ +Q+ Q G+ + +R + Q+ Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM---GEQEEQMRKQEEQM 236 Score = 32.3 bits (72), Expect = 1.7 Identities = 35/204 (17%), Positives = 91/204 (44%), Gaps = 8/204 (3%) Query: 362 MSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRE 421 M E+Q+ Q E + E +QK + +V + E +R+ Q + Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274 Query: 422 TDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTK--QKTISAVGEQLLPTVEHLQ 479 + M +E + + ++RE+ E ++++ EQ + ++ + EQ+ E + Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334 Query: 480 LELDQL-KSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFS 538 + +Q+ + + W+ + E + +Q++ + QVR+ + + +++Q E+ +++ Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ-EEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393 Query: 539 SQFVSK----GDLQTMLRDLQLQI 558 Q + G+ + +R+ + Q+ Sbjct: 394 EQMGEQKEQMGEQKEQMREQEEQM 417 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 39.3 bits (90), Expect = 0.014 Identities = 39/201 (19%), Positives = 82/201 (40%), Gaps = 6/201 (2%) Query: 382 NLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDI 441 +L ++ +++LQ D+ G SA R + Q + + +E E MS ++++ Sbjct: 378 HLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTL--REEKECSMSRVQEL 435 Query: 442 LGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCET 501 L E + + S V +QL EHL+ EL+ L +L + G Sbjct: 436 ETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSR 495 Query: 502 VDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQR----FSSQFVSKGDLQTMLRDLQLQ 557 ++ QE +++ +L + + + + +Q S +L+ L +LQ Sbjct: 496 LNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSG 555 Query: 558 ILRNVTHHVSVTKQLPTSEAV 578 ++ ++ +T L + + V Sbjct: 556 FVKLTNENMEITSALQSEQHV 576 Score = 39.3 bits (90), Expect = 0.014 Identities = 61/230 (26%), Positives = 93/230 (40%), Gaps = 42/230 (18%) Query: 391 QKLQARVD----QMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLR 446 Q+LQA + ++EG A A V+D G ++E E R+ LE Sbjct: 463 QQLQAEAEHLRKELEGLAGQLQAQVQDNEG-------LSRLNREQEERLLELERAAELWG 515 Query: 447 EKSEAIQKELE--QTKQKTISAV---GEQLLPTVEHLQLELDQLKSE-------LSSWRH 494 E++EA ++ LE Q + TIS +L + LQ +L +E L S +H Sbjct: 516 EQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQH 575 Query: 495 VKTGC--------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGD 546 VK E + ++E V+++ +E L DQ G L+Q + + K Sbjct: 576 VKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEV 635 Query: 547 LQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQAR 596 L L LQ Q++ QL EA AV+E + E Q R Sbjct: 636 LHNQLL-LQTQLV----------DQLQQQEAQGKAVAEMARQELQETQER 674 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 38.9 bits (89), Expect = 0.019 Identities = 44/232 (18%), Positives = 109/232 (46%), Gaps = 21/232 (9%) Query: 381 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 440 + L+E + LQA++ Q + A VR+ + R + H++ +++ D Sbjct: 190 QQLQEKEEFISTLQAQLSQTQAEQAAQQV-VRE---KDARFETQVRLHEDELLQLVTQAD 245 Query: 441 ILGKLREKSEAIQKELEQTKQKTISAVG-----EQLLPTVEH----LQLELDQLKSELSS 491 + ++++K +Q++LE+ ++ + +Q L E L +L Q+++E ++ Sbjct: 246 VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 305 Query: 492 WRH-VKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTM 550 R+ V+T E + E+++++V E KL F Q+ + LL++F ++ +L++ Sbjct: 306 LRNTVETEREESKILLEKMELEVAER-KLSFHNLQE--EMHHLLEQFEQAGQAQAELESR 362 Query: 551 LRDLQ----LQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAI 598 L+ ++ +H +S+ K ++ A+ + + + + +A+ Sbjct: 363 YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAV 414 Score = 37.7 bits (86), Expect = 0.042 Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 16/202 (7%) Query: 360 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDA-VGQP 418 H + ++A L + + L +L+ L+K + + +EG A ++++ Sbjct: 2298 HLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYE 2357 Query: 419 PRETDFMAFHQ-----EHEVRMSHLEDILGKLREKSEAIQ---KELEQTKQKTISAVGEQ 470 ETD A + E+ M + I+ L K EAIQ EL Q K I + E Sbjct: 2358 QLETDLQASRELTSRLHEEINMKE-QKIISLLSGKEEAIQVAIAELRQQHDKEIKEL-EN 2415 Query: 471 LLPTVEHLQLEL-DQLKSELSSWRHVKTGCETV--DAVQER--VDVQVREMVKLLFSEDQ 525 LL E + L ++ K + + +T+ + +Q++ +D V+ M L D+ Sbjct: 2416 LLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2475 Query: 526 QGGSLEQLLQRFSSQFVSKGDL 547 G +QL +R S + K L Sbjct: 2476 IVGDYQQLEERHLSIILEKDQL 2497 Score = 31.6 bits (70), Expect = 3.0 Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 24/216 (11%) Query: 371 SLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQE 430 SLS C L LT +KL ++ ++ S ++ + +E + + E Sbjct: 1564 SLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYE 1623 Query: 431 H----EVRMSHL--------EDILGKLREKSEAIQKELEQTKQKTISAVGE------QLL 472 + R+ H+ +++ GKLR +EA +KE E+ Q+ + E + Sbjct: 1624 NVSNEAERIQHVVEAVRQEKQELYGKLRS-TEANKKETEKQLQEAEQEMEEMKEKMRKFA 1682 Query: 473 PTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQ 532 + + LEL++ L + H D +E ++ + + ++ E Sbjct: 1683 KSKQQKILELEEENDRLRAEVH-----PAGDTAKECMETLLSSNASMKEELERVKMEYET 1737 Query: 533 LLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSV 568 L ++F S K L ++DL+ QI NV+ ++ Sbjct: 1738 LSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL 1773 >gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sapiens] Length = 1185 Score = 38.5 bits (88), Expect = 0.024 Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 21/185 (11%) Query: 320 VLNWASMHRTQRVDDPQ--DVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCH 377 + N SMHR + Q + + +L+Q L+ +E P + + Q+VA+LS Sbjct: 350 IANKDSMHRQTEDKNRQLQERLELAEQKLQQTLR-KAETLP-EVEAELAQRVAALSKAEE 407 Query: 378 HHG---ENLRELTTLL----QKLQARVDQMEGGAAGPSASVRDAVGQPPRET-DFMAFHQ 429 HG E LR++ L Q+LQ R Q E + + D V + E+ + + H Sbjct: 408 RHGNIEERLRQMEAQLEEKNQELQ-RARQREKMNEEHNKRLSDTVDKLLSESNERLQLHL 466 Query: 430 EHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSEL 489 + RM+ LED LRE E+ +K+LE+T+ +QL+ +E L+ ELD ++ Sbjct: 467 KE--RMAALEDKNSLLREV-ESAKKQLEETQHDK-----DQLVLNIEALRAELDHMRLRG 518 Query: 490 SSWRH 494 +S H Sbjct: 519 ASLHH 523 >gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens] Length = 1202 Score = 38.5 bits (88), Expect = 0.024 Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 21/185 (11%) Query: 320 VLNWASMHRTQRVDDPQ--DVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCH 377 + N SMHR + Q + + +L+Q L+ +E P + + Q+VA+LS Sbjct: 350 IANKDSMHRQTEDKNRQLQERLELAEQKLQQTLR-KAETLP-EVEAELAQRVAALSKAEE 407 Query: 378 HHG---ENLRELTTLL----QKLQARVDQMEGGAAGPSASVRDAVGQPPRET-DFMAFHQ 429 HG E LR++ L Q+LQ R Q E + + D V + E+ + + H Sbjct: 408 RHGNIEERLRQMEAQLEEKNQELQ-RARQREKMNEEHNKRLSDTVDKLLSESNERLQLHL 466 Query: 430 EHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSEL 489 + RM+ LED LRE E+ +K+LE+T+ +QL+ +E L+ ELD ++ Sbjct: 467 KE--RMAALEDKNSLLREV-ESAKKQLEETQHDK-----DQLVLNIEALRAELDHMRLRG 518 Query: 490 SSWRH 494 +S H Sbjct: 519 ASLHH 523 >gi|154090997 coiled-coil domain containing 13 [Homo sapiens] Length = 715 Score = 38.5 bits (88), Expect = 0.024 Identities = 44/191 (23%), Positives = 90/191 (47%), Gaps = 14/191 (7%) Query: 367 QQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMA 426 QQ+ S G + + L + +Q+L+ ++ Q +AG +AS +V PR+ ++ Sbjct: 253 QQLLSSPGTWRGRAQQILVLQSKVQELEKQLGQARSQSAG-TASDELSVYPDPRK---LS 308 Query: 427 FHQEHEVRMSHLE----DILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLEL 482 +++ +R+ LE + L KL + + +Q+ELE+ K+K E + + L E+ Sbjct: 309 AQEKNLLRIRSLEREKQEGLEKLASERDVLQRELEELKKKF-----EGMRSRNKLLSSEM 363 Query: 483 DQLKSELSSW-RHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQF 541 LKS++ + + E +DA+ +++ + L E++ S L Q+ +S+ Sbjct: 364 KTLKSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHHLDQQLNSEA 423 Query: 542 VSKGDLQTMLR 552 L L+ Sbjct: 424 QRSNSLVAQLQ 434 >gi|170784854 PTPRF interacting protein, binding protein 2 (liprin beta 2) [Homo sapiens] Length = 876 Score = 38.1 bits (87), Expect = 0.032 Identities = 40/173 (23%), Positives = 82/173 (47%), Gaps = 32/173 (18%) Query: 350 LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSA 409 L+GD E+ + QV+ L+ Q GE +R+L L+ Q +++ E Sbjct: 114 LEGDKES--------LILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE------EM 159 Query: 410 SVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLRE-KSEAIQKELEQTKQKTISAVG 468 ++ + + ET + D++ ++ E K + + E EQ +Q+ Sbjct: 160 LQQELLSRTSLETQKL--------------DLMTEVSELKLKLVGMEKEQREQEEKQRKA 205 Query: 469 EQLLPTVEHLQLELDQLKSELS--SWRHVKTGCETVDAVQERVDVQVREMVKL 519 E+LL + HL++++++L++E + W+ T E V +QE+V ++ E+ +L Sbjct: 206 EELLQELRHLKIKVEELENERNQYEWKLKATKAE-VAQLQEQVALKDAEIERL 257 >gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] Length = 1219 Score = 38.1 bits (87), Expect = 0.032 Identities = 65/286 (22%), Positives = 118/286 (41%), Gaps = 32/286 (11%) Query: 365 VEQQVASLSGQCHH-------HGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQ 417 V +++A+ + Q H H + EL L + D + G A + + Q Sbjct: 641 VTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSEL--Q 698 Query: 418 PPRETDFMAFHQEH------EVRMSHLEDILGKLREKSEAIQKELEQTKQKTI---SAVG 468 E F E E++++ LE+ L LR + E+++K L + K+K+ S Sbjct: 699 ETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAE 758 Query: 469 EQLLPTVEHLQLELDQLKSELSSWR--HVKTGCETVDAVQERVDVQVREMVK--LLFSED 524 E++ + Q ELD+L+ L R + E + VQ + Q + L ++D Sbjct: 759 EEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKD 818 Query: 525 QQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSE 584 + +++ + + LQ LQ QI + K+L +++ +S V E Sbjct: 819 EHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSGV-E 877 Query: 585 AGASGITEAQARAIVNSALKLYSQDKTGMVDFALES--GGGSILST 628 A AS +E + + I+N + + +F LE G +IL T Sbjct: 878 AAASDPSE-KVKKIMNQVFQSLRR------EFELEESYNGRTILGT 916 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 37.7 bits (86), Expect = 0.042 Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%) Query: 381 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 440 + + LT KL+ +VD +EG D + + QE + + + + Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078 Query: 441 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 500 L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E Sbjct: 1079 QLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137 Query: 501 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 560 ++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+ Sbjct: 1138 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1188 Query: 561 NVTHHVSVTKQLPTSEA 577 + ++ K+ S A Sbjct: 1189 HEATAATLRKKHADSVA 1205 Score = 33.9 bits (76), Expect = 0.60 Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 28/141 (19%) Query: 443 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 495 GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R + Sbjct: 1524 GKRIHELEKIKKQVEQEKSELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1580 Query: 496 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL------LQRFS 538 E +D ++Q +D ++R + + + G L ++ R + Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640 Query: 539 SQFV-SKGDLQTMLRDLQLQI 558 ++ + + + Q +L+D QL + Sbjct: 1641 AEALRNYRNTQAILKDTQLHL 1661 Score = 30.0 bits (66), Expect = 8.7 Identities = 18/78 (23%), Positives = 44/78 (56%), Gaps = 4/78 (5%) Query: 390 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 445 +QKL+ARV ++EG +AV + R+ + + E + + + L+D++ KL Sbjct: 1816 IQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKL 1875 Query: 446 REKSEAIQKELEQTKQKT 463 + K ++ +++ E+ ++++ Sbjct: 1876 QAKVKSYKRQAEEAEEQS 1893 >gi|4504063 golgin 97 [Homo sapiens] Length = 767 Score = 37.7 bits (86), Expect = 0.042 Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 16/147 (10%) Query: 427 FHQEHEVRMSHL----EDILGKLREKSEAIQKELEQTKQKTISA--VGEQLLPTVEHLQL 480 F Q+ ++ H+ E+ LGK+ ++ EA +EL +T+++ +++ + L +E LQ Sbjct: 176 FQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQR 235 Query: 481 ELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQ 540 L+ + KTG E+ E+ + +++ +++ L + LQ+ +++ Sbjct: 236 HYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSID----------LQKVTAE 285 Query: 541 FVSKGDLQTMLRDLQLQILRNVTHHVS 567 K D+ T L++ + + + ++S Sbjct: 286 TQEKEDVITHLQEKVASLEKRLEQNLS 312 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 37.4 bits (85), Expect = 0.054 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 5/131 (3%) Query: 360 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPP 419 H + ++ L +C + L E +LQKLQ V+Q E + Q Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ-- 1177 Query: 420 RETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGE--QLLPTVEH 477 ++ F + QE E S +DI LR + E ++ ELE+ + + + V E +L + Sbjct: 1178 MQSSFTSSEQELERLRSENKDI-ENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTE 1236 Query: 478 LQLELDQLKSE 488 LQ +LD SE Sbjct: 1237 LQKKLDDSYSE 1247 Score = 31.2 bits (69), Expect = 3.9 Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 48/267 (17%) Query: 328 RTQRVDDPQD---VFKPTTSRLKQPLQGDSEAFPWH------------WMSGVEQQVASL 372 +TQ + D QD +FK +LKQ + +FP H +SG+ ++ SL Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1018 Query: 373 SGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHE 432 H + +L + + ME A ++D V + +E Q+ E Sbjct: 1019 KDAVEHQRKKNNDLR------EKNWEAME-ALASTEKMLQDKVNKTSKER-----QQQVE 1066 Query: 433 VRMSHLEDILGKLREK---------SEAIQKELEQTKQKTISAVGEQLLPTVEH------ 477 +++L KL K E + ++ K+ G + + +EH Sbjct: 1067 AVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEAD 1126 Query: 478 -----LQLELDQLKSELSSWRHVKTGCE-TVDAVQERVDVQVREMVKLLFSEDQQGGSLE 531 LQLE ++ KS L+ + + +V+ + + V+V E K + S E Sbjct: 1127 EMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSE 1186 Query: 532 QLLQRFSSQFVSKGDLQTMLRDLQLQI 558 Q L+R S+ +L+ L++++ Sbjct: 1187 QELERLRSENKDIENLRREREHLEMEL 1213 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 37.4 bits (85), Expect = 0.054 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 5/131 (3%) Query: 360 HWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPP 419 H + ++ L +C + L E +LQKLQ V+Q E + Q Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ-- 1177 Query: 420 RETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGE--QLLPTVEH 477 ++ F + QE E S +DI LR + E ++ ELE+ + + + V E +L + Sbjct: 1178 MQSSFTSSEQELERLRSENKDI-ENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTE 1236 Query: 478 LQLELDQLKSE 488 LQ +LD SE Sbjct: 1237 LQKKLDDSYSE 1247 Score = 31.2 bits (69), Expect = 3.9 Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 48/267 (17%) Query: 328 RTQRVDDPQD---VFKPTTSRLKQPLQGDSEAFPWH------------WMSGVEQQVASL 372 +TQ + D QD +FK +LKQ + +FP H +SG+ ++ SL Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1018 Query: 373 SGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHE 432 H + +L + + ME A ++D V + +E Q+ E Sbjct: 1019 KDAVEHQRKKNNDLR------EKNWEAME-ALASTEKMLQDKVNKTSKER-----QQQVE 1066 Query: 433 VRMSHLEDILGKLREK---------SEAIQKELEQTKQKTISAVGEQLLPTVEH------ 477 +++L KL K E + ++ K+ G + + +EH Sbjct: 1067 AVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEAD 1126 Query: 478 -----LQLELDQLKSELSSWRHVKTGCE-TVDAVQERVDVQVREMVKLLFSEDQQGGSLE 531 LQLE ++ KS L+ + + +V+ + + V+V E K + S E Sbjct: 1127 EMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSE 1186 Query: 532 QLLQRFSSQFVSKGDLQTMLRDLQLQI 558 Q L+R S+ +L+ L++++ Sbjct: 1187 QELERLRSENKDIENLRREREHLEMEL 1213 >gi|238908495 similar to pleckstrin homology domain protein (5V327) [Homo sapiens] Length = 506 Score = 37.0 bits (84), Expect = 0.071 Identities = 39/183 (21%), Positives = 84/183 (45%), Gaps = 16/183 (8%) Query: 439 EDILGKLREKSEAIQKELEQTKQ-----KTISAVGEQLLPTVEHLQLELDQLKSELSSWR 493 ++ L KL E++E + + EQ ++ + + A +Q V+ L++E +Q+K EL Sbjct: 164 QEYLDKLMEETEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELTA 223 Query: 494 HVKTGCE--------TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKG 545 G E +++Q+ ++ E K L ++ L+ L + S Q G Sbjct: 224 RCLKGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEENENHLQTLANQ-SEQPPPSG 282 Query: 546 DLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKL 605 L + LR ++ ++ + + + K++ +E A+ E +Q++A+ NS +L Sbjct: 283 GLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEE--EREFYSSQSQALQNSLQEL 340 Query: 606 YSQ 608 ++ Sbjct: 341 TAE 343 >gi|21493045 A-kinase anchor protein 6 [Homo sapiens] Length = 2319 Score = 37.0 bits (84), Expect = 0.071 Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 43/198 (21%) Query: 428 HQE-HEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLK 486 HQ+ +E +E + KL E + + + +E T+ T + E+D LK Sbjct: 770 HQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPP-------------KAEMDDLK 816 Query: 487 SELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGD 546 L + K ++ A++E V+ + ++++L+ S L+ +L+ +SQ+ Sbjct: 817 LYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHK---AGLKDMLRMIASQW----- 868 Query: 547 LQTMLRDLQLQILRNVTHHVSVTKQLPTSEAV-----VSAVSEAGASG--------ITEA 593 ++LQ QI R H + + L T +A VS E G EA Sbjct: 869 -----KELQRQIKRQ---HSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEA 920 Query: 594 QARAIVNSALKLYSQDKT 611 Q A+ +LKLYS+ T Sbjct: 921 QRDAVEQMSLKLYSEQYT 938 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 36.6 bits (83), Expect = 0.093 Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%) Query: 381 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 440 + + LT KL+ +VD +EG D + + QE + + + + Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 441 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 500 L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E Sbjct: 1081 QLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139 Query: 501 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 560 ++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+ Sbjct: 1140 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1190 Query: 561 NVTHHVSVTKQLPTSEA 577 + ++ K+ S A Sbjct: 1191 HEATAATLRKKHADSVA 1207 Score = 31.6 bits (70), Expect = 3.0 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 21/109 (19%) Query: 443 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 495 GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R + Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1582 Query: 496 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL 533 E +D ++Q +D ++R + + + G L ++ Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631 Score = 31.2 bits (69), Expect = 3.9 Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 6/110 (5%) Query: 390 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 445 +QKL+ARV ++EG +AV + R + + E + + + L+D++ KL Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877 Query: 446 REKSEAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWR 493 + K ++ +++ E+ +++ T A +L +E + D +S+++ R Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 36.6 bits (83), Expect = 0.093 Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 10/197 (5%) Query: 381 ENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLED 440 + + LT KL+ +VD +EG D + + QE + + + + Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 441 ILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCE 500 L + +K E L Q+K + A+G QL ++ LQ +++L+ E+ + R + E Sbjct: 1081 QLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139 Query: 501 TVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILR 560 ++R D+ RE+ ++ ++ GG+ ++ + + + Q M RDL+ L+ Sbjct: 1140 -----KQRSDLS-RELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQ 1190 Query: 561 NVTHHVSVTKQLPTSEA 577 + ++ K+ S A Sbjct: 1191 HEATAATLRKKHADSVA 1207 Score = 31.6 bits (70), Expect = 3.0 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 21/109 (19%) Query: 443 GKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEH-------LQLELDQLKSELSSWRHV 495 GK + E I+K++EQ K + +A+ E+ ++EH +QLEL+Q+KSE+ R + Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAAL-EEAEASLEHEEGKILRIQLELNQVKSEVD--RKI 1582 Query: 496 KTGCETVD-----------AVQERVDVQVREMVKLLFSEDQQGGSLEQL 533 E +D ++Q +D ++R + + + G L ++ Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631 Score = 31.2 bits (69), Expect = 3.9 Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 6/110 (5%) Query: 390 LQKLQARVDQMEGGAAGPSASVRDAV---GQPPRETDFMAFHQEHEVR-MSHLEDILGKL 445 +QKL+ARV ++EG +AV + R + + E + + + L+D++ KL Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1877 Query: 446 REKSEAIQKELEQTKQK--TISAVGEQLLPTVEHLQLELDQLKSELSSWR 493 + K ++ +++ E+ +++ T A +L +E + D +S+++ R Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.132 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,519,242 Number of Sequences: 37866 Number of extensions: 1277614 Number of successful extensions: 5195 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 198 Number of HSP's that attempted gapping in prelim test: 4895 Number of HSP's gapped (non-prelim): 474 length of query: 785 length of database: 18,247,518 effective HSP length: 110 effective length of query: 675 effective length of database: 14,082,258 effective search space: 9505524150 effective search space used: 9505524150 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.