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Search of human proteins with 194018732
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018732 hypothetical protein LOC100130958 [Homo sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018732 hypothetical protein LOC100130958 [Homo sapiens] 472 e-133
gi|219555718 synaptonemal complex central element protein 1 isof... 197 7e-51
gi|219555716 synaptonemal complex central element protein 1 isof... 197 7e-51
gi|18640754 synaptonemal complex central element protein 1 isofo... 185 3e-47
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 55 7e-08
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 50 2e-06
gi|42794779 myosin 18A isoform b [Homo sapiens] 50 2e-06
gi|28416946 myosin 18A isoform a [Homo sapiens] 50 2e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 47 1e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 1e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 1e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 1e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 47 1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 1e-05
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 46 3e-05
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 46 3e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 46 3e-05
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 46 3e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 46 3e-05
gi|148746195 trichohyalin [Homo sapiens] 45 4e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 45 4e-05
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 45 4e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 6e-05
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 45 6e-05
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 45 6e-05
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 45 6e-05
gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo s... 45 7e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 44 1e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 44 1e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 44 1e-04
>gi|194018732 hypothetical protein LOC100130958 [Homo sapiens]
Length = 242
Score = 472 bits (1214), Expect = e-133
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQ 60
MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQ
Sbjct: 1 MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQ 60
Query: 61 AKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR 120
AKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR
Sbjct: 61 AKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR 120
Query: 121 LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLH 180
LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLH
Sbjct: 121 LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLH 180
Query: 181 SPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPEPPVAAPD 240
SPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPEPPVAAPD
Sbjct: 181 SPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPEPPVAAPD 240
Query: 241 AL 242
AL
Sbjct: 241 AL 242
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 197 bits (501), Expect = 7e-51
Identities = 120/250 (48%), Positives = 158/250 (63%), Gaps = 39/250 (15%)
Query: 12 APEATEEAEGQ-AKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELR 70
A + E+A GQ S K EDL+ MV KLQK GSLEP++E LI+RIN++QQAKKK++++L
Sbjct: 16 AVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLG 75
Query: 71 ETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR---------- 120
E ++ EAL +ELDSL+GEKVHL+E+L KKQE LRIL++HCQEKESEA R
Sbjct: 76 EARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKE 135
Query: 121 --------------------LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQ 160
L QLEDLMGQHKDLW+FHM E RLA+EI AL+ SKEQ
Sbjct: 136 RISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE-RLAKEICALDSSKEQ 194
Query: 161 LLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGL-------KAELEIFGEQVRSAPEVG 213
LL E +LV+A L +V+ +L S EG +++GL A +++F E+ R A E+
Sbjct: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
Query: 214 AGEGEAGPEL 223
A + +L
Sbjct: 255 AAAAQRHQQL 264
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 197 bits (501), Expect = 7e-51
Identities = 120/250 (48%), Positives = 158/250 (63%), Gaps = 39/250 (15%)
Query: 12 APEATEEAEGQ-AKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELR 70
A + E+A GQ S K EDL+ MV KLQK GSLEP++E LI+RIN++QQAKKK++++L
Sbjct: 16 AVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLG 75
Query: 71 ETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR---------- 120
E ++ EAL +ELDSL+GEKVHL+E+L KKQE LRIL++HCQEKESEA R
Sbjct: 76 EARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKE 135
Query: 121 --------------------LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQ 160
L QLEDLMGQHKDLW+FHM E RLA+EI AL+ SKEQ
Sbjct: 136 RISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE-RLAKEICALDSSKEQ 194
Query: 161 LLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGL-------KAELEIFGEQVRSAPEVG 213
LL E +LV+A L +V+ +L S EG +++GL A +++F E+ R A E+
Sbjct: 195 LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELL 254
Query: 214 AGEGEAGPEL 223
A + +L
Sbjct: 255 AAAAQRHQQL 264
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 185 bits (470), Expect = 3e-47
Identities = 110/229 (48%), Positives = 146/229 (63%), Gaps = 38/229 (16%)
Query: 32 LAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKV 91
+ MV KLQK GSLEP++E LI+RIN++QQAKKK++++L E ++ EAL +ELDSL+GEKV
Sbjct: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
Query: 92 HLEEVLGKKQEALRILQMHCQEKESEAQR------------------------------L 121
HL+E+L KKQE LRIL++HCQEKESEA R L
Sbjct: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
Query: 122 DVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHS 181
QLEDLMGQHKDLW+FHM E RLA+EI AL+ SKEQLL E +LV+A L +V+ +L S
Sbjct: 121 AFEEQLEDLMGQHKDLWDFHMPE-RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCS 179
Query: 182 PPEVEGAMAVNDGL-------KAELEIFGEQVRSAPEVGAGEGEAGPEL 223
EG +++GL A +++F E+ R A E+ A + +L
Sbjct: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQL 228
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 54.7 bits (130), Expect = 7e-08
Identities = 46/193 (23%), Positives = 89/193 (46%), Gaps = 16/193 (8%)
Query: 23 AKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRE 82
+K L+ ++L + KL+K+ + +E + N ++Q + +++ + L +E
Sbjct: 484 SKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQE 543
Query: 83 LDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHM 142
+ LN E V E L K ++ + HCQ K + +++ M ++ L E H
Sbjct: 544 REDLNKELVQASERL--KNQSKELKDAHCQRKLA----------MQEFMEINERLTELHT 591
Query: 143 LEQRLAREIRALERSKEQLLSERRLVRAKLREVER---RLHSPPEVEGAMAVND-GLKAE 198
+Q+LAR +R E + ++ + +R +LR ER L E A A D L+ +
Sbjct: 592 QKQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQ 651
Query: 199 LEIFGEQVRSAPE 211
E + +Q+ + E
Sbjct: 652 SEHYSKQLENELE 664
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 50.1 bits (118), Expect = 2e-06
Identities = 53/179 (29%), Positives = 90/179 (50%), Gaps = 27/179 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K K L++E + TEE EGQ K L+ + L +K KE +L+ DLQQ ++
Sbjct: 715 KEKYLSLE--QKTEELEGQIKKLEADSL---EVKASKEQALQ-----------DLQQQRQ 758
Query: 64 KSSE-ELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRL- 121
+++ ELR T L + L E + ++ ++ L+ KK EAL ++ ++E E Q L
Sbjct: 759 LNTDLELRAT-ELSKQLEMEKEIVSSTRLDLQ----KKSEALESIKQKLTKQEEEKQILK 813
Query: 122 -DVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
D ++ QH++L + Q E++ ++ KE L++E V+ KL +V L
Sbjct: 814 QDFETLSQETKIQHEEL---NNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSL 869
Score = 37.4 bits (85), Expect = 0.012
Identities = 35/160 (21%), Positives = 79/160 (49%), Gaps = 11/160 (6%)
Query: 20 EGQAKSLKTE-DLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEA 78
E + + LK + + L+ K+Q E L +I+ + + +LQ+ K + + E ++ +
Sbjct: 806 EEEKQILKQDFETLSQETKIQHE-ELNNRIQ---TTVTELQKVKMEKEALMTELSTVKDK 861
Query: 79 LHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLW 138
L + DSL K E+ K + A+ L+ C+E + + Q Q+E+ + + K+L
Sbjct: 862 LSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ-----VQMENTLKEQKELK 916
Query: 139 EFHMLEQRLAREIR-ALERSKEQLLSERRLVRAKLREVER 177
+ E+ + +++ L +EQL+ + ++ +E ++
Sbjct: 917 KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ 956
Score = 31.6 bits (70), Expect = 0.65
Identities = 40/192 (20%), Positives = 88/192 (45%), Gaps = 34/192 (17%)
Query: 10 VEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSL-EPQIEDLISRINDLQQAKKKSSEE 68
++ +AT E + K + ++ + +QKE SL E ++ + S++ ++++ K + +E
Sbjct: 1080 LKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Query: 69 LRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLE 128
+ + L+ EL S E + +E+ K ++Q Q+L+++G+ +
Sbjct: 1140 ITK-------LNEELKSHKLESI--KEITNLKDAKQLLIQ----------QKLELQGKAD 1180
Query: 129 DLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSP-PEVEG 187
L + + +E R + K+Q+ E ++ + E E +LHS E E
Sbjct: 1181 SL-------------KAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEV 1227
Query: 188 AMAVNDGLKAEL 199
M ++ +A+L
Sbjct: 1228 GMKKHEENEAKL 1239
Score = 29.6 bits (65), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 49 EDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQ 108
+ L SR++ + + + EL E + L EL + + HL+ + Q+ +
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKE 406
Query: 109 MHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFH--MLEQRLAREIRALERSKEQLLSERR 166
H + +SE +L + L+ + L E H + EQR + ++ KEQ +++ +
Sbjct: 407 QHGLQLQSEINQLHSK-----LLETERQLGEAHGRLKEQRQLSSEKLMD--KEQQVADLQ 459
Query: 167 LVRAKLRE 174
L ++L E
Sbjct: 460 LKLSRLEE 467
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 49.7 bits (117), Expect = 2e-06
Identities = 66/245 (26%), Positives = 109/245 (44%), Gaps = 29/245 (11%)
Query: 5 LKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKK 64
L L AP E A+ + + ++E A +K +K ++E +IEDL +I+D+ +AK
Sbjct: 1672 LDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK--AMEVEIEDLHLQIDDIAKAK-- 1727
Query: 65 SSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR 124
AL +L L EK ++ L + QE + L + K + AQ
Sbjct: 1728 ------------TALEEQLSRLQREKNEIQNRLEEDQEDMNELMK--KHKAAVAQASRDL 1773
Query: 125 GQLEDLMGQHKDLWEFHMLEQRLAREIRALERS---KEQLLSERRLV---RAKLREVERR 178
Q+ DL Q L E + +Q L +++AL+ EQ + ++ LV AK+RE+E R
Sbjct: 1774 AQINDLQAQ---LEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETR 1830
Query: 179 LH-SPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPR-ARDEEDPEPPV 236
L +V+ ++ LK +E E+ E E L R RD ++ +
Sbjct: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL 1890
Query: 237 AAPDA 241
A +A
Sbjct: 1891 ARKEA 1895
Score = 41.6 bits (96), Expect = 6e-04
Identities = 51/207 (24%), Positives = 97/207 (46%), Gaps = 16/207 (7%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K K E + + + ++ ED M ++K + Q +++INDLQ +
Sbjct: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE 1784
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV 123
++++E +E +AL +++ L E+ +++ L +QEA +I ++ E E +R V
Sbjct: 1785 EANKEKQELQEKLQALQSQVEFL--EQSMVDKSLVSRQEA-KIREL---ETRLEFERTQV 1838
Query: 124 RGQLEDLMGQHKDLWE--FHMLEQRLAREIRALERSK------EQLLSERRLVRAKLREV 175
+ +LE L + K+ E +QR+A E R E++K E + K E
Sbjct: 1839 K-RLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
Query: 176 ERRLHS-PPEVEGAMAVNDGLKAELEI 201
R+ H ++E A N L+A+L++
Sbjct: 1898 SRKKHELEMDLESLEAANQSLQADLKL 1924
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 6/144 (4%)
Query: 39 QKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEV-L 97
QK SLE +++D+ S+ + + + K ++LR+ + + ELD G LE+ L
Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
Query: 98 GKKQEALRILQMHCQEKESEAQRLDVRGQ--LEDLMGQHKDLWEFHMLEQRLAREIRALE 155
+ E R+ Q H +E ES + ++ Q + L L E + +Q++ RE R LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 156 RSKEQLLSERRLVRAKLREVERRL 179
K LS++ V + E E+RL
Sbjct: 1634 -GKLATLSDQ--VNRRDFESEKRL 1654
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 49.7 bits (117), Expect = 2e-06
Identities = 66/245 (26%), Positives = 109/245 (44%), Gaps = 29/245 (11%)
Query: 5 LKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKK 64
L L AP E A+ + + ++E A +K +K ++E +IEDL +I+D+ +AK
Sbjct: 1672 LDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK--AMEVEIEDLHLQIDDIAKAK-- 1727
Query: 65 SSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR 124
AL +L L EK ++ L + QE + L + K + AQ
Sbjct: 1728 ------------TALEEQLSRLQREKNEIQNRLEEDQEDMNELMK--KHKAAVAQASRDL 1773
Query: 125 GQLEDLMGQHKDLWEFHMLEQRLAREIRALERS---KEQLLSERRLV---RAKLREVERR 178
Q+ DL Q L E + +Q L +++AL+ EQ + ++ LV AK+RE+E R
Sbjct: 1774 AQINDLQAQ---LEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETR 1830
Query: 179 LH-SPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPR-ARDEEDPEPPV 236
L +V+ ++ LK +E E+ E E L R RD ++ +
Sbjct: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL 1890
Query: 237 AAPDA 241
A +A
Sbjct: 1891 ARKEA 1895
Score = 41.6 bits (96), Expect = 6e-04
Identities = 51/207 (24%), Positives = 97/207 (46%), Gaps = 16/207 (7%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K K E + + + ++ ED M ++K + Q +++INDLQ +
Sbjct: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE 1784
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV 123
++++E +E +AL +++ L E+ +++ L +QEA +I ++ E E +R V
Sbjct: 1785 EANKEKQELQEKLQALQSQVEFL--EQSMVDKSLVSRQEA-KIREL---ETRLEFERTQV 1838
Query: 124 RGQLEDLMGQHKDLWE--FHMLEQRLAREIRALERSK------EQLLSERRLVRAKLREV 175
+ +LE L + K+ E +QR+A E R E++K E + K E
Sbjct: 1839 K-RLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
Query: 176 ERRLHS-PPEVEGAMAVNDGLKAELEI 201
R+ H ++E A N L+A+L++
Sbjct: 1898 SRKKHELEMDLESLEAANQSLQADLKL 1924
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 6/144 (4%)
Query: 39 QKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEV-L 97
QK SLE +++D+ S+ + + + K ++LR+ + + ELD G LE+ L
Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
Query: 98 GKKQEALRILQMHCQEKESEAQRLDVRGQ--LEDLMGQHKDLWEFHMLEQRLAREIRALE 155
+ E R+ Q H +E ES + ++ Q + L L E + +Q++ RE R LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 156 RSKEQLLSERRLVRAKLREVERRL 179
K LS++ V + E E+RL
Sbjct: 1634 -GKLATLSDQ--VNRRDFESEKRL 1654
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 47.4 bits (111), Expect = 1e-05
Identities = 59/226 (26%), Positives = 97/226 (42%), Gaps = 26/226 (11%)
Query: 12 APEATEEAEGQAKSLKTE--DLLAMVIKL---------------QKEGSLEPQIEDLISR 54
A ++ E +LKTE DL A +KL Q+ LE + + + SR
Sbjct: 573 AEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSR 632
Query: 55 INDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEK 114
+ +QA+ +L E EAL + L + EE + Q LR +Q +EK
Sbjct: 633 MEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ---EEK 689
Query: 115 ESEAQRL-DVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLR 173
E ++L + R Q E Q L + H +R + + KE L+ E+ + +L+
Sbjct: 690 EEIQKKLSESRHQQEAATTQ---LEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ 746
Query: 174 EVER-RLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGE 218
VER R +++G + + L++ L +Q S EV G+ E
Sbjct: 747 AVERDRQDLAEQLQGLSSAKELLESSL-FEAQQQNSVIEVTKGQLE 791
Score = 42.4 bits (98), Expect = 4e-04
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 24/182 (13%)
Query: 22 QAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRI---------NDLQQAKKKSSEELRET 72
QAK + ++ + ++L E S Q D +R L+Q K +E+ +
Sbjct: 799 QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQL 858
Query: 73 HSLWEA--------LHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR 124
WE L + L+SL EK+ LE L ++Q + +Q +E+ ++A+ +
Sbjct: 859 REKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQ 918
Query: 125 GQLEDLMGQHKDLWEFHMLEQRLAREIRALER----SKEQLLSERR---LVRAKLREVER 177
QLE + L ++ LA + LER K Q L E+ +++ +L+E +R
Sbjct: 919 MQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQR 978
Query: 178 RL 179
L
Sbjct: 979 EL 980
Score = 40.4 bits (93), Expect = 0.001
Identities = 55/204 (26%), Positives = 97/204 (47%), Gaps = 34/204 (16%)
Query: 18 EAEGQAKSL--KTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSL 75
EAE + ++L K L A + K ++ G+ +L + + D+Q+ K++ ++L E+
Sbjct: 649 EAEKRREALWEKNTHLEAQLQKAEEAGA------ELQADLRDIQEEKEEIQKKLSESRHQ 702
Query: 76 WEALHRELDSLNGEKVHLEEVLGK---KQEAL----RILQMHCQEKESEAQRLDVRGQLE 128
EA +L+ L+ E EEVL + ++EAL L++ Q E + Q D+ QL+
Sbjct: 703 QEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQ--DLAEQLQ 760
Query: 129 DLMGQHKDLWEFHMLEQ------------RLAREIRALERSKEQLLSERRLVRAKLREVE 176
L K+L E + E +L +I+ + ++KE + E R ++ +L + E
Sbjct: 761 GL-SSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL-DTE 818
Query: 177 RRLHSPPEVEGAMAVNDGLKAELE 200
R S E E A +AE E
Sbjct: 819 R---SQAEQERDAAARQLAQAEQE 839
Score = 36.2 bits (82), Expect = 0.026
Identities = 50/177 (28%), Positives = 77/177 (43%), Gaps = 22/177 (12%)
Query: 44 LEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLE--------- 94
L Q+ +N LQQ + EE + + L E D+L G+ V L+
Sbjct: 405 LRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE 464
Query: 95 -EVLGKKQEALRILQMHCQEKES-EAQRLDVRGQL--EDLMGQHKDLW-EFHML---EQR 146
E+L K +E LR Q+ E+E+ +R++V QL + GQ ++ E H+ +R
Sbjct: 465 RELLQKAREELR-QQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERER 523
Query: 147 LAREIRALERSKEQLLSERRLVRAKLR----EVERRLHSPPEVEGAMAVNDGLKAEL 199
L + LE + + LSE +R L E E EV A+A + AEL
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAEL 580
Score = 36.2 bits (82), Expect = 0.026
Identities = 40/167 (23%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLW 76
+E EGQ ++ + L + + L+ E S E Q + S+I+DL+ + EL+E
Sbjct: 1577 KELEGQRETQRVA-LTHLTLDLE-ERSQELQAQS--SQIHDLESHSTVLARELQERDQEV 1632
Query: 77 EALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRL------DVRGQLEDL 130
++ +++ L +K HL + L ++ + L + + Q E + R D+ L
Sbjct: 1633 KSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSL 1692
Query: 131 MGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLV-RAKLREVE 176
+ ++L L Q A E + +++ L +L+ R K +EVE
Sbjct: 1693 RERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVE 1739
Score = 35.8 bits (81), Expect = 0.034
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 23/154 (14%)
Query: 40 KEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHL------ 93
K+ SLE ++ +L + LQ +++ + E E L ++L + HL
Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVE 1366
Query: 94 -----------EEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWE-FH 141
EE L + AL++ + + AQ L +G+L+ + Q K L E
Sbjct: 1367 ARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELK--VAQGKALQENLA 1424
Query: 142 MLEQRLA---REIRALERSKEQLLSERRLVRAKL 172
+L Q LA E+ L ++L +R + +A L
Sbjct: 1425 LLTQTLAEREEEVETLRGQIQELEKQREMQKAAL 1458
Score = 32.3 bits (72), Expect = 0.38
Identities = 43/186 (23%), Positives = 82/186 (44%), Gaps = 22/186 (11%)
Query: 10 VEAPEATEEAEGQAK-SLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEE 68
+E EA+ E Q + SL ++ A ++L+ S E Q+E L + QA+ ++
Sbjct: 1125 LEELEASHITEQQLRASLWAQEAKAAQLQLRLR-STESQLEALAAEQQPGNQAQAQA--- 1180
Query: 69 LRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLE 128
+ SL+ AL + L S+ + E+ G A + + + ++ A+ L RG L
Sbjct: 1181 --QLASLYSALQQALGSVCESR---PELSGGGDSAPSVWGL--EPDQNGARSLFKRGPLL 1233
Query: 129 DLMGQ----------HKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
+ H+DLW+ L +++ LE +E+ V +L++++R+
Sbjct: 1234 TALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Query: 179 LHSPPE 184
L E
Sbjct: 1294 LSQNQE 1299
Score = 32.0 bits (71), Expect = 0.50
Identities = 38/188 (20%), Positives = 78/188 (41%), Gaps = 16/188 (8%)
Query: 8 LNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSE 67
L + EA E+ E + +SL+++ A Q++ LE ++ ++ K+K+
Sbjct: 1783 LQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADA 1842
Query: 68 ---ELRETHSLWEALHRELDSLNGEKVHLEEVL---GKKQEALR--ILQMHCQEKESEAQ 119
L + H + H EL + LEE L G++ +AL + + + +E E
Sbjct: 1843 LQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKA 1902
Query: 120 RLDVRGQLEDLMGQH-------KDLW-EFHMLEQRLAREIRALERSKEQLLSERRLVRAK 171
L ++ Q + +H +D W + + + +E+ AL + + RA+
Sbjct: 1903 LLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARAR 1962
Query: 172 LREVERRL 179
++ L
Sbjct: 1963 AEALQEAL 1970
Score = 29.3 bits (64), Expect = 3.2
Identities = 48/238 (20%), Positives = 98/238 (41%), Gaps = 31/238 (13%)
Query: 14 EATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
+A EE G ++ E A+ + LQ++ + + Q ++ +R LQ + ++ L+E
Sbjct: 1883 QALEEVLGDLRAESREQEKAL-LALQQQCAEQAQEHEVETRA--LQDSWLQAQAVLKERD 1939
Query: 74 SLWEALHRELDSLNGEKVH-------LEEVLGKKQEALRILQMHCQE-----KESEAQRL 121
EAL E S ++ L+E LGK AL+ + H E + EA
Sbjct: 1940 QELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTA 1999
Query: 122 DVRGQLEDLMGQHKDLWEFHMLEQ--------RLAREIRALERSKEQLLSERRLVRAKLR 173
++ L+ + L E +++ R +++ L+++ Q E R + + +
Sbjct: 2000 TLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQ 2059
Query: 174 EVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEED 231
+E+ L A V + + E + G++ G + +L A+ E++
Sbjct: 2060 LLEKSL--------AQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/199 (25%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 15 ATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
A +E E QA + +D +A L+K LE I DL ++ + A+ K+ ++ R+
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--KESEAQRLDVRGQ----L 127
EAL EL+ +E+ K+++ + +L+ E + EAQ ++R + +
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 128 EDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEG 187
E+L Q L +F + L + + LE+ L E R++ +EVE H ++E
Sbjct: 1206 EELTEQ---LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE---HKKKKLEA 1259
Query: 188 AM-----AVNDGLKAELEI 201
+ +DG +A E+
Sbjct: 1260 QVQELQSKCSDGERARAEL 1278
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 18/190 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K+KPL +E E QAK ED L + Q++ E ++++L + + L + K
Sbjct: 840 KVKPL---LQVTRQEEEMQAK----EDELQKTKERQQKA--ENELKELEQKHSQLTEEKN 890
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGK-----KQEALRILQMHCQEKESEA 118
E+L+ L+ L +K LEE+L + ++E R Q+ + K+
Sbjct: 891 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 119 QRLDVRGQLEDLMGQHKDLWEFHMLEQ----RLAREIRALERSKEQLLSERRLVRAKLRE 174
Q LD+ QLE+ + L + + +L EI ++ +L ER+L+ ++ +
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 175 VERRLHSPPE 184
+ L E
Sbjct: 1011 LTTNLAEEEE 1020
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/180 (20%), Positives = 84/180 (46%), Gaps = 20/180 (11%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWE 77
E E + + + + LA K + EG L+ DL + + + ++++ ++LR+ + +
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 78 ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDL 137
REL+ + +E+ +E EK++++ D+ EDL +
Sbjct: 1656 DFQRELEDARASR---DEIFATAKE---------NEKKAKSLEADLMQLQEDLAAAERAR 1703
Query: 138 WEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAM-AVNDGLK 196
+ + ++ LA E+ + + L E+R + A++ ++E L E +G M A++D ++
Sbjct: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE---EEQGNMEAMSDRVR 1760
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 29 EDLLAMVIKLQK-EGSLEPQIEDLI-------SRINDLQQAKKKSSEELRETHSLWEALH 80
E+ A KL+K + L+ +++DL+ +++L++ ++K + L E ++
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 81 RELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES-EAQRLDVRGQLEDLMGQHKDLWE 139
E D E E K R L+ + KE E ++ ++EDL+ D+
Sbjct: 1469 DERDRAEAEAREKET---KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV-- 1523
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLKAE 198
+ + LE+SK L ++ ++ +L E+E L + + + + VN LK +
Sbjct: 1524 --------GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575
Query: 199 LE 200
E
Sbjct: 1576 FE 1577
Score = 32.3 bits (72), Expect = 0.38
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 36/234 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQI----EDLISRINDLQ 59
+L+ L + + E E A++ + E +K SLE + EDL + +
Sbjct: 1646 QLRKLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704
Query: 60 QA---KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES 116
QA K++ +EEL + S AL E L LEE L ++Q + + ++
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVE 176
+A++L E Q E +++QL + + +R+KL E+E
Sbjct: 1765 QAEQLSNELATERSTAQKN-------------------ESARQQLERQNKELRSKLHEME 1805
Query: 177 RRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
+ S + + +A + A+LE EQV E A E +A + + +D++
Sbjct: 1806 GAVKS--KFKSTIAALEAKIAQLE---EQV----EQEAREKQAATKSLKQKDKK 1850
Score = 31.2 bits (69), Expect = 0.85
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 59/224 (26%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIEDLISRINDLQQAKKKSSEELR----ET 72
EAEG+A IKL K+ SL Q++D + + + K S +LR E
Sbjct: 1298 EAEGKA------------IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 73 HSLWEALHRELDSLNGEKVH------------------------LEEVLGKKQEALRILQ 108
+SL + L E+++ + H LEE + Q+ + L
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 109 MHCQEKESEAQRLD-----VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLS 163
+EK + +L+ ++ +L+DL+ + +++L + +R +QLL+
Sbjct: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-------QRQLVSNLEKKQRKFDQLLA 1458
Query: 164 ERRLVRAKL------REVERRLHSPPEVEGAMAVNDGLKAELEI 201
E + + +K E E R + A A+ + L+A+ E+
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1502
Score = 27.7 bits (60), Expect = 9.4
Identities = 31/149 (20%), Positives = 57/149 (38%), Gaps = 24/149 (16%)
Query: 1 MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGS----------------- 43
+ K+ L + + E + KSLK +D I LQ E
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
Query: 44 ---LEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEE---VL 97
L+ Q+E+ + ++K EL E EA+ RE+++L + E V
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1938
Query: 98 GKKQEALRILQ-MHCQEKESEAQRLDVRG 125
++ R+++ E+E++ + D G
Sbjct: 1939 SRRSGGRRVIENADGSEEETDTRDADFNG 1967
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/199 (25%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 15 ATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
A +E E QA + +D +A L+K LE I DL ++ + A+ K+ ++ R+
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--KESEAQRLDVRGQ----L 127
EAL EL+ +E+ K+++ + +L+ E + EAQ ++R + +
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 128 EDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEG 187
E+L Q L +F + L + + LE+ L E R++ +EVE H ++E
Sbjct: 1213 EELTEQ---LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE---HKKKKLEA 1266
Query: 188 AM-----AVNDGLKAELEI 201
+ +DG +A E+
Sbjct: 1267 QVQELQSKCSDGERARAEL 1285
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 18/190 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K+KPL +E E QAK ED L + Q++ E ++++L + + L + K
Sbjct: 847 KVKPL---LQVTRQEEEMQAK----EDELQKTKERQQKA--ENELKELEQKHSQLTEEKN 897
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGK-----KQEALRILQMHCQEKESEA 118
E+L+ L+ L +K LEE+L + ++E R Q+ + K+
Sbjct: 898 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 119 QRLDVRGQLEDLMGQHKDLWEFHMLEQ----RLAREIRALERSKEQLLSERRLVRAKLRE 174
Q LD+ QLE+ + L + + +L EI ++ +L ER+L+ ++ +
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 175 VERRLHSPPE 184
+ L E
Sbjct: 1018 LTTNLAEEEE 1027
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/180 (20%), Positives = 84/180 (46%), Gaps = 20/180 (11%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWE 77
E E + + + + LA K + EG L+ DL + + + ++++ ++LR+ + +
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 78 ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDL 137
REL+ + +E+ +E EK++++ D+ EDL +
Sbjct: 1663 DFQRELEDARASR---DEIFATAKE---------NEKKAKSLEADLMQLQEDLAAAERAR 1710
Query: 138 WEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAM-AVNDGLK 196
+ + ++ LA E+ + + L E+R + A++ ++E L E +G M A++D ++
Sbjct: 1711 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE---EEQGNMEAMSDRVR 1767
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 29 EDLLAMVIKLQK-EGSLEPQIEDLI-------SRINDLQQAKKKSSEELRETHSLWEALH 80
E+ A KL+K + L+ +++DL+ +++L++ ++K + L E ++
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 81 RELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES-EAQRLDVRGQLEDLMGQHKDLWE 139
E D E E K R L+ + KE E ++ ++EDL+ D+
Sbjct: 1476 DERDRAEAEAREKET---KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV-- 1530
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLKAE 198
+ + LE+SK L ++ ++ +L E+E L + + + + VN LK +
Sbjct: 1531 --------GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 199 LE 200
E
Sbjct: 1583 FE 1584
Score = 32.3 bits (72), Expect = 0.38
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 36/234 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQI----EDLISRINDLQ 59
+L+ L + + E E A++ + E +K SLE + EDL + +
Sbjct: 1653 QLRKLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711
Query: 60 QA---KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES 116
QA K++ +EEL + S AL E L LEE L ++Q + + ++
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVE 176
+A++L E Q E +++QL + + +R+KL E+E
Sbjct: 1772 QAEQLSNELATERSTAQKN-------------------ESARQQLERQNKELRSKLHEME 1812
Query: 177 RRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
+ S + + +A + A+LE EQV E A E +A + + +D++
Sbjct: 1813 GAVKS--KFKSTIAALEAKIAQLE---EQV----EQEAREKQAATKSLKQKDKK 1857
Score = 31.2 bits (69), Expect = 0.85
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 59/224 (26%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIEDLISRINDLQQAKKKSSEELR----ET 72
EAEG+A IKL K+ SL Q++D + + + K S +LR E
Sbjct: 1305 EAEGKA------------IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 73 HSLWEALHRELDSLNGEKVH------------------------LEEVLGKKQEALRILQ 108
+SL + L E+++ + H LEE + Q+ + L
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 109 MHCQEKESEAQRLD-----VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLS 163
+EK + +L+ ++ +L+DL+ + +++L + +R +QLL+
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-------QRQLVSNLEKKQRKFDQLLA 1465
Query: 164 ERRLVRAKL------REVERRLHSPPEVEGAMAVNDGLKAELEI 201
E + + +K E E R + A A+ + L+A+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1509
Score = 27.7 bits (60), Expect = 9.4
Identities = 31/149 (20%), Positives = 57/149 (38%), Gaps = 24/149 (16%)
Query: 1 MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGS----------------- 43
+ K+ L + + E + KSLK +D I LQ E
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 44 ---LEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEE---VL 97
L+ Q+E+ + ++K EL E EA+ RE+++L + E V
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1945
Query: 98 GKKQEALRILQ-MHCQEKESEAQRLDVRG 125
++ R+++ E+E++ + D G
Sbjct: 1946 SRRSGGRRVIENADGSEEETDTRDADFNG 1974
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/199 (25%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 15 ATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
A +E E QA + +D +A L+K LE I DL ++ + A+ K+ ++ R+
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--KESEAQRLDVRGQ----L 127
EAL EL+ +E+ K+++ + +L+ E + EAQ ++R + +
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 128 EDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEG 187
E+L Q L +F + L + + LE+ L E R++ +EVE H ++E
Sbjct: 1213 EELTEQ---LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE---HKKKKLEA 1266
Query: 188 AM-----AVNDGLKAELEI 201
+ +DG +A E+
Sbjct: 1267 QVQELQSKCSDGERARAEL 1285
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 18/190 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K+KPL +E E QAK ED L + Q++ E ++++L + + L + K
Sbjct: 847 KVKPL---LQVTRQEEEMQAK----EDELQKTKERQQKA--ENELKELEQKHSQLTEEKN 897
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGK-----KQEALRILQMHCQEKESEA 118
E+L+ L+ L +K LEE+L + ++E R Q+ + K+
Sbjct: 898 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 119 QRLDVRGQLEDLMGQHKDLWEFHMLEQ----RLAREIRALERSKEQLLSERRLVRAKLRE 174
Q LD+ QLE+ + L + + +L EI ++ +L ER+L+ ++ +
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 175 VERRLHSPPE 184
+ L E
Sbjct: 1018 LTTNLAEEEE 1027
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 4/187 (2%)
Query: 3 GKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQA- 61
G ++ ++ +AT++AE + L TE A + ++ LE Q ++L S++++++ A
Sbjct: 1757 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ-QLERQNKELRSKLHEMEGAV 1815
Query: 62 KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALR--ILQMHCQEKESEAQ 119
K K + + L +++ EK + L +K + L+ +LQ+ + K +E
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1875
Query: 120 RLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
+ + + L E QR+ R L+R ++ + ++ ++ +L
Sbjct: 1876 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Query: 180 HSPPEVE 186
PP E
Sbjct: 1936 RGPPPQE 1942
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/180 (20%), Positives = 84/180 (46%), Gaps = 20/180 (11%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWE 77
E E + + + + LA K + EG L+ DL + + + ++++ ++LR+ + +
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 78 ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDL 137
REL+ + +E+ +E EK++++ D+ EDL +
Sbjct: 1663 DFQRELEDARASR---DEIFATAKE---------NEKKAKSLEADLMQLQEDLAAAERAR 1710
Query: 138 WEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAM-AVNDGLK 196
+ + ++ LA E+ + + L E+R + A++ ++E L E +G M A++D ++
Sbjct: 1711 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE---EEQGNMEAMSDRVR 1767
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 29 EDLLAMVIKLQK-EGSLEPQIEDLI-------SRINDLQQAKKKSSEELRETHSLWEALH 80
E+ A KL+K + L+ +++DL+ +++L++ ++K + L E ++
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 81 RELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES-EAQRLDVRGQLEDLMGQHKDLWE 139
E D E E K R L+ + KE E ++ ++EDL+ D+
Sbjct: 1476 DERDRAEAEAREKET---KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV-- 1530
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLKAE 198
+ + LE+SK L ++ ++ +L E+E L + + + + VN LK +
Sbjct: 1531 --------GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 199 LE 200
E
Sbjct: 1583 FE 1584
Score = 32.3 bits (72), Expect = 0.38
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 36/234 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQI----EDLISRINDLQ 59
+L+ L + + E E A++ + E +K SLE + EDL + +
Sbjct: 1653 QLRKLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711
Query: 60 QA---KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES 116
QA K++ +EEL + S AL E L LEE L ++Q + + ++
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVE 176
+A++L E Q E +++QL + + +R+KL E+E
Sbjct: 1772 QAEQLSNELATERSTAQKN-------------------ESARQQLERQNKELRSKLHEME 1812
Query: 177 RRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
+ S + + +A + A+LE EQV E A E +A + + +D++
Sbjct: 1813 GAVKS--KFKSTIAALEAKIAQLE---EQV----EQEAREKQAATKSLKQKDKK 1857
Score = 31.2 bits (69), Expect = 0.85
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 59/224 (26%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIEDLISRINDLQQAKKKSSEELR----ET 72
EAEG+A IKL K+ SL Q++D + + + K S +LR E
Sbjct: 1305 EAEGKA------------IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 73 HSLWEALHRELDSLNGEKVH------------------------LEEVLGKKQEALRILQ 108
+SL + L E+++ + H LEE + Q+ + L
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 109 MHCQEKESEAQRLD-----VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLS 163
+EK + +L+ ++ +L+DL+ + +++L + +R +QLL+
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-------QRQLVSNLEKKQRKFDQLLA 1465
Query: 164 ERRLVRAKL------REVERRLHSPPEVEGAMAVNDGLKAELEI 201
E + + +K E E R + A A+ + L+A+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1509
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/199 (25%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 15 ATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
A +E E QA + +D +A L+K LE I DL ++ + A+ K+ ++ R+
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--KESEAQRLDVRGQ----L 127
EAL EL+ +E+ K+++ + +L+ E + EAQ ++R + +
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 128 EDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEG 187
E+L Q L +F + L + + LE+ L E R++ +EVE H ++E
Sbjct: 1206 EELTEQ---LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE---HKKKKLEA 1259
Query: 188 AM-----AVNDGLKAELEI 201
+ +DG +A E+
Sbjct: 1260 QVQELQSKCSDGERARAEL 1278
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 18/190 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K+KPL +E E QAK ED L + Q++ E ++++L + + L + K
Sbjct: 840 KVKPL---LQVTRQEEEMQAK----EDELQKTKERQQKA--ENELKELEQKHSQLTEEKN 890
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGK-----KQEALRILQMHCQEKESEA 118
E+L+ L+ L +K LEE+L + ++E R Q+ + K+
Sbjct: 891 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 119 QRLDVRGQLEDLMGQHKDLWEFHMLEQ----RLAREIRALERSKEQLLSERRLVRAKLRE 174
Q LD+ QLE+ + L + + +L EI ++ +L ER+L+ ++ +
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 175 VERRLHSPPE 184
+ L E
Sbjct: 1011 LTTNLAEEEE 1020
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 4/187 (2%)
Query: 3 GKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQA- 61
G ++ ++ +AT++AE + L TE A + ++ LE Q ++L S++++++ A
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ-QLERQNKELRSKLHEMEGAV 1808
Query: 62 KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALR--ILQMHCQEKESEAQ 119
K K + + L +++ EK + L +K + L+ +LQ+ + K +E
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
Query: 120 RLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
+ + + L E QR+ R L+R ++ + ++ ++ +L
Sbjct: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Query: 180 HSPPEVE 186
PP E
Sbjct: 1929 RGPPPQE 1935
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/180 (20%), Positives = 84/180 (46%), Gaps = 20/180 (11%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWE 77
E E + + + + LA K + EG L+ DL + + + ++++ ++LR+ + +
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 78 ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDL 137
REL+ + +E+ +E EK++++ D+ EDL +
Sbjct: 1656 DFQRELEDARASR---DEIFATAKE---------NEKKAKSLEADLMQLQEDLAAAERAR 1703
Query: 138 WEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAM-AVNDGLK 196
+ + ++ LA E+ + + L E+R + A++ ++E L E +G M A++D ++
Sbjct: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE---EEQGNMEAMSDRVR 1760
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 29 EDLLAMVIKLQK-EGSLEPQIEDLI-------SRINDLQQAKKKSSEELRETHSLWEALH 80
E+ A KL+K + L+ +++DL+ +++L++ ++K + L E ++
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 81 RELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES-EAQRLDVRGQLEDLMGQHKDLWE 139
E D E E K R L+ + KE E ++ ++EDL+ D+
Sbjct: 1469 DERDRAEAEAREKET---KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV-- 1523
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLKAE 198
+ + LE+SK L ++ ++ +L E+E L + + + + VN LK +
Sbjct: 1524 --------GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575
Query: 199 LE 200
E
Sbjct: 1576 FE 1577
Score = 32.3 bits (72), Expect = 0.38
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 36/234 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQI----EDLISRINDLQ 59
+L+ L + + E E A++ + E +K SLE + EDL + +
Sbjct: 1646 QLRKLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704
Query: 60 QA---KKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES 116
QA K++ +EEL + S AL E L LEE L ++Q + + ++
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVE 176
+A++L E Q E +++QL + + +R+KL E+E
Sbjct: 1765 QAEQLSNELATERSTAQKN-------------------ESARQQLERQNKELRSKLHEME 1805
Query: 177 RRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
+ S + + +A + A+LE EQV E A E +A + + +D++
Sbjct: 1806 GAVKS--KFKSTIAALEAKIAQLE---EQV----EQEAREKQAATKSLKQKDKK 1850
Score = 31.2 bits (69), Expect = 0.85
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 59/224 (26%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIEDLISRINDLQQAKKKSSEELR----ET 72
EAEG+A IKL K+ SL Q++D + + + K S +LR E
Sbjct: 1298 EAEGKA------------IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 73 HSLWEALHRELDSLNGEKVH------------------------LEEVLGKKQEALRILQ 108
+SL + L E+++ + H LEE + Q+ + L
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 109 MHCQEKESEAQRLD-----VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLS 163
+EK + +L+ ++ +L+DL+ + +++L + +R +QLL+
Sbjct: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-------QRQLVSNLEKKQRKFDQLLA 1458
Query: 164 ERRLVRAKL------REVERRLHSPPEVEGAMAVNDGLKAELEI 201
E + + +K E E R + A A+ + L+A+ E+
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1502
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 47.0 bits (110), Expect = 1e-05
Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 29/203 (14%)
Query: 14 EATEEA------EGQAKSLKTEDLLAMVIKLQK-EGSLEPQIEDLISRIN-------DLQ 59
E+ EEA + +A S + E+ KL+K + L+ +++DL ++ +L+
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1447
Query: 60 QAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKES-EA 118
+ +KK + L E S+ E D E E K R L+ + KE E
Sbjct: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET---KALSLARALEEALEAKEEFER 1504
Query: 119 QRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
Q +R +EDLM D+ + + LE+SK L + +R +L E+E
Sbjct: 1505 QNKQLRADMEDLMSSKDDV----------GKNVHELEKSKRALEQQVEEMRTQLEELEDE 1554
Query: 179 LHSPPEVEGAMAVN-DGLKAELE 200
L + + + + VN +KA+ E
Sbjct: 1555 LQATEDAKLRLEVNMQAMKAQFE 1577
Score = 43.9 bits (102), Expect = 1e-04
Identities = 42/181 (23%), Positives = 81/181 (44%), Gaps = 11/181 (6%)
Query: 8 LNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSE 67
+N++A +A E + Q + + E+ ++IK +E LE ++ED + +KKK
Sbjct: 1567 VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE--LEAELEDERKQRALAVASKKKMEI 1624
Query: 68 ELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRIL-----QMHCQEKESEAQRLD 122
+L++ + EA ++ D + + L+ + Q L ++ Q KESE +
Sbjct: 1625 DLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKS 1684
Query: 123 VRGQL----EDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
+ ++ E+L + LA EI K LL E+R + A++ ++E
Sbjct: 1685 LEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 1744
Query: 179 L 179
L
Sbjct: 1745 L 1745
Score = 38.5 bits (88), Expect = 0.005
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 21/192 (10%)
Query: 19 AEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWE 77
A G ++L + L +V +LQ + L+ E + N ++ K+ SEEL E
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL-------E 1149
Query: 78 ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--KESEAQRLDVRGQ----LEDLM 131
AL EL+ +E+ K+++ + L+ +E K EAQ D+R + LE+L
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELS 1209
Query: 132 GQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRL---VRAKLREVERRLHSP-PEVEG 187
Q + F + L + + LE ++L E ++ V+A+ ++L + E+
Sbjct: 1210 EQLEQAKRF---KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266
Query: 188 AMAVNDGLKAEL 199
++ D L+ EL
Sbjct: 1267 KVSEGDRLRVEL 1278
Score = 37.0 bits (84), Expect = 0.015
Identities = 52/228 (22%), Positives = 101/228 (44%), Gaps = 37/228 (16%)
Query: 3 GKLKPLNVEAPEATEEAEGQAKSLKTE-DLLAMVIKLQ-----KEGSLEPQIEDLISRIN 56
G+L+ + + + EE A+ L+ E +L A +++ K+ LE + DL SR+
Sbjct: 873 GELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVE 932
Query: 57 D-------LQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQ- 108
+ LQ KKK +++ + L EKV E + K +E + +L+
Sbjct: 933 EEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 992
Query: 109 ---MHCQEKESEAQRL-DVRGQLEDLMGQHKDLWEFHM--------LEQRLAREIRA--- 153
+EK+ R+ + QL + + K+L + LE+RL +E +
Sbjct: 993 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQE 1052
Query: 154 LERSKEQLLSERRLVRAKLREVERRL--------HSPPEVEGAMAVND 193
LE++K +L E ++ ++ E++ ++ E++GA+A D
Sbjct: 1053 LEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
Score = 37.0 bits (84), Expect = 0.015
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 10/168 (5%)
Query: 14 EATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
E +E+ E QAK K ++ K+G LE ++L + LQQ K +S + ++
Sbjct: 1207 ELSEQLE-QAKRFKAN------LEKNKQG-LETDNKELACEVKVLQQVKAESEHKRKKLD 1258
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRL--DVRGQLEDLM 131
+ + LH ++ + +V L E K Q L + +E E + + D L
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ 1318
Query: 132 GQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
+ L E + L+ IR LE K L ++ + +E+++
Sbjct: 1319 DTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 36.6 bits (83), Expect = 0.020
Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 25/176 (14%)
Query: 55 INDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEK 114
I+DL++ KK + +E E R+LD GE L++ + + Q + L++ +K
Sbjct: 1036 ISDLEERLKKEEKTRQEL----EKAKRKLD---GETTDLQDQIAELQAQIDELKLQLAKK 1088
Query: 115 ESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLRE 174
E E Q RG E L HK+ + + L +I L+ E + R + R+
Sbjct: 1089 EEELQGALARGDDETL---HKN--NALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD 1143
Query: 175 VERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
+ L + LK ELE + + E+ + EL +A +EE
Sbjct: 1144 LSEEL-------------EALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Score = 36.6 bits (83), Expect = 0.020
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 47/212 (22%)
Query: 14 EATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIE-------DLISRINDLQQAKKKSS 66
EA E E + ++L M I L+ LE QIE ++I ++ LQ K
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLK---DLEAQIEAANKARDEVIKQLRKLQAQMKDYQ 1658
Query: 67 EELRETHSLWEAL-------HRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEA- 118
EL E + + + ++L SL E + L+E L + A R + E E
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIT 1718
Query: 119 -------------QRLDVR-GQLEDLMGQHKDLWEF------------HMLEQRLAREIR 152
+RL+ R QLE+ + + + E L LA E
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 153 ALERS---KEQLLSERRLVRAKLREVERRLHS 181
A ++S ++QL + + ++AKL+E+E + S
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKS 1810
Score = 35.0 bits (79), Expect = 0.059
Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 17/182 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLK----TEDLLAMVIKLQKEG--SLEPQIEDLISRIND 57
KLK L E + EE ++ + D LA I G +L + L +RI
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
Query: 58 LQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESE 117
L++ ++ + + + ++D+LN E K A ++ E
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA---------RQQLE 1791
Query: 118 AQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVER 177
Q +++ +L++L G K +F L +I LE EQ ER +R E+
Sbjct: 1792 RQNKELKAKLQELEGAVKS--KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 178 RL 179
+L
Sbjct: 1850 KL 1851
Score = 33.9 bits (76), Expect = 0.13
Identities = 42/176 (23%), Positives = 79/176 (44%), Gaps = 28/176 (15%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K+KPL +E E QAK E+LL + +K+ +E ++E++ ++
Sbjct: 840 KVKPL---LQVTRQEEELQAKD---EELLKVK---EKQTKVEGELEEM----------ER 880
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV 123
K + L E + L E L E + + + KKQE IL + ES + +
Sbjct: 881 KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEIL----HDLESRVEEEEE 936
Query: 124 RGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
R Q ++ K + H+ Q L ++ E ++++L E+ AK++++E +
Sbjct: 937 RNQ---ILQNEKKKMQAHI--QDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEI 987
Score = 32.0 bits (71), Expect = 0.50
Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 18/121 (14%)
Query: 95 EVLGKKQE---ALRILQMHCQEK------------ESEAQRLDVRGQLEDLMGQHKDLWE 139
+ KKQ+ AL++LQ +C L V Q E+L + ++L +
Sbjct: 804 KAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLK 863
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAEL 199
+ ++ E+ +ER +QLL E+ ++ +L+ E+ +A K EL
Sbjct: 864 VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAK---KQEL 920
Query: 200 E 200
E
Sbjct: 921 E 921
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 46.2 bits (108), Expect = 3e-05
Identities = 52/196 (26%), Positives = 95/196 (48%), Gaps = 15/196 (7%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSL-EPQIEDLISRINDLQQAKKKSSEELR-ETHS 74
+E E + K+L E V KLQ+ + + + E+L+ + N + + K K+ E++R + S
Sbjct: 242 QEVEKKQKTL-IEMYKTQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMES 300
Query: 75 LWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQH 134
+ L R DSL + L E QE+L+ + C ++E + L +GQ++ G H
Sbjct: 301 HLKELERVCDSLTAAERRLHEC----QESLQCCKGKCADQEHTIREL--QGQVD---GNH 351
Query: 135 KDLWEFHMLEQRLAREIRA--LERSKEQLLSERRLVRAKLREVERRL-HSPPEVEGAMAV 191
L + + E+ +++ L++ EQ+ +E + + KL E L HS + + A
Sbjct: 352 NLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAE 411
Query: 192 NDGLKAELEIFGEQVR 207
L +LE E+ R
Sbjct: 412 YTALARQLEAALEEGR 427
Score = 35.8 bits (81), Expect = 0.034
Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 29/172 (16%)
Query: 34 MVIKLQKEGSLEPQIEDLISRINDLQQAK---KKSSEE-LRETHSL-------------- 75
++ K + E +E + +I+ + DL++ + K S EE LR+ HS+
Sbjct: 161 VIEKTELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTKL 220
Query: 76 ---WEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMG 132
AL E+ S+ E L+EV K++ + + + Q+ + A+ V+ + E+L+
Sbjct: 221 KTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAE--IVKSRCENLL- 277
Query: 133 QHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPE 184
HK+ + + + + + + E L E V L ERRLH E
Sbjct: 278 -HKN----NQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQE 324
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 46.2 bits (108), Expect = 3e-05
Identities = 52/196 (26%), Positives = 95/196 (48%), Gaps = 15/196 (7%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSL-EPQIEDLISRINDLQQAKKKSSEELR-ETHS 74
+E E + K+L E V KLQ+ + + + E+L+ + N + + K K+ E++R + S
Sbjct: 373 QEVEKKQKTL-IEMYKTQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMES 431
Query: 75 LWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQH 134
+ L R DSL + L E QE+L+ + C ++E + L +GQ++ G H
Sbjct: 432 HLKELERVCDSLTAAERRLHEC----QESLQCCKGKCADQEHTIREL--QGQVD---GNH 482
Query: 135 KDLWEFHMLEQRLAREIRA--LERSKEQLLSERRLVRAKLREVERRL-HSPPEVEGAMAV 191
L + + E+ +++ L++ EQ+ +E + + KL E L HS + + A
Sbjct: 483 NLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAE 542
Query: 192 NDGLKAELEIFGEQVR 207
L +LE E+ R
Sbjct: 543 YTALARQLEAALEEGR 558
Score = 35.8 bits (81), Expect = 0.034
Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 29/172 (16%)
Query: 34 MVIKLQKEGSLEPQIEDLISRINDLQQAK---KKSSEE-LRETHSL-------------- 75
++ K + E +E + +I+ + DL++ + K S EE LR+ HS+
Sbjct: 292 VIEKTELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTKL 351
Query: 76 ---WEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMG 132
AL E+ S+ E L+EV K++ + + + Q+ + A+ V+ + E+L+
Sbjct: 352 KTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAE--IVKSRCENLL- 408
Query: 133 QHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPE 184
HK+ + + + + + + E L E V L ERRLH E
Sbjct: 409 -HKN----NQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQE 455
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/196 (23%), Positives = 87/196 (44%), Gaps = 22/196 (11%)
Query: 15 ATEEAEGQAKSLKTEDLLAMV-IKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETH 73
A +E E QA + E+ A + L+K LE QI +L + + ++ K+ ++ R+
Sbjct: 1079 AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLG 1138
Query: 74 SLWEALHRELDSLNGEKVHLEEVLGKKQEALRIL-------------------QMHCQEK 114
EAL EL+ +E+ K+++ + IL Q H Q
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV 1198
Query: 115 ESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLRE 174
E A++L+ +++ + + K E E LA E++ L + K +R+ V A+L+E
Sbjct: 1199 EELAEQLEQTKRVKANLEKAKQTLENERGE--LANEVKVLLQGKGDSEHKRKKVEAQLQE 1256
Query: 175 VERRLHSPPEVEGAMA 190
++ + + V +A
Sbjct: 1257 LQVKFNEGERVRTELA 1272
Score = 42.7 bits (99), Expect = 3e-04
Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 25/187 (13%)
Query: 25 SLKTEDLLAMVIKLQKEGS-LEPQIEDLISRIN-------DLQQAKKKSSEELRETHSLW 76
S + E+ +A KL+K + L+ +++DL+ ++ +L++ +KK + L E ++
Sbjct: 1398 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTIS 1457
Query: 77 EALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLD--VRGQLEDLMGQH 134
E D E E K R L+ E+++E +RL+ R ++EDLM
Sbjct: 1458 AKYAEERDRAEAEAREKET---KALSLARALE-EAMEQKAELERLNKQFRTEMEDLMSSK 1513
Query: 135 KDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-D 193
D+ + + LE+SK L + ++ +L E+E L + + + + VN
Sbjct: 1514 DDV----------GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563
Query: 194 GLKAELE 200
+KA+ E
Sbjct: 1564 AMKAQFE 1570
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/180 (22%), Positives = 82/180 (45%), Gaps = 20/180 (11%)
Query: 6 KPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKS 65
K ++ + E + AE +A+ +T+ L SL +E+ + + +L++ K+
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKAL-----------SLARALEEAMEQKAELERLNKQF 1502
Query: 66 SEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV-- 123
E+ + S + + + + L K LE+ + + + L L+ Q E RL+V
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Query: 124 ---RGQLE-DLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
+ Q E DL G+ + E +++L R++R +E E +R + A +++E L
Sbjct: 1563 QAMKAQFERDLQGRDEQSEE---KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL 1619
Score = 40.0 bits (92), Expect = 0.002
Identities = 58/244 (23%), Positives = 105/244 (43%), Gaps = 40/244 (16%)
Query: 1 MAGKLKPLNVEAPEATEE-AEGQAKSLK-TEDLLAMVIKLQKEGSL----EPQIEDLISR 54
+A K+ L VE T ++ +KS K T+D A+ +LQ L Q L ++
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 55 INDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHL--------------EEVLGKK 100
+ ++ K E+L E L +++ +L+ + + EEV K
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 101 QEALRILQMHCQEKESEAQRLD-----VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALE 155
Q+ L L +EK + +L+ ++ +L+DL+ DL +++ A + +
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL---VDLDH----QRQSACNLEKKQ 1443
Query: 156 RSKEQLLSERRLVRAKL------REVERRLHSPPEVEGAMAVNDGL--KAELEIFGEQVR 207
+ +QLL+E + + AK E E R + A A+ + + KAELE +Q R
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
Query: 208 SAPE 211
+ E
Sbjct: 1504 TEME 1507
Score = 40.0 bits (92), Expect = 0.002
Identities = 48/199 (24%), Positives = 87/199 (43%), Gaps = 23/199 (11%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
K K L + E E E + K +M + +K+ LE ++DL + I+ + +
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQR------SMAVAARKK--LEMDLKDLEAHIDSANKNRD 1634
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV 123
++ ++LR+ + + RELD + EE+L + +E + L K EA+ + +
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASR---EEILAQAKENEKKL------KSMEAEMIQL 1685
Query: 124 RGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPP 183
+ E+L + + LA EI L E+R + A++ ++E L
Sbjct: 1686 Q---EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE-- 1740
Query: 184 EVEGAMAVNDGL-KAELEI 201
E +ND L KA L+I
Sbjct: 1741 EQGNTELINDRLKKANLQI 1759
Score = 37.4 bits (85), Expect = 0.012
Identities = 44/182 (24%), Positives = 77/182 (42%), Gaps = 18/182 (9%)
Query: 10 VEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEEL 69
V+ E AE + ++T M KLQ + L+ + E L + +L+ +EL
Sbjct: 855 VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE-LCAEAEELRARLTAKKQEL 913
Query: 70 RET-HSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLE 128
E H L + E + HL+ K Q+ ++ L+ +E+ES Q+L QLE
Sbjct: 914 EEICHDLEARVEEEEERCQ----HLQAEKKKMQQNIQELEEQLEEEESARQKL----QLE 965
Query: 129 DLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGA 188
+ + K ++L E LE +L E++L+ ++ E L E +
Sbjct: 966 KVTTEAK--------LKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 189 MA 190
+A
Sbjct: 1018 LA 1019
Score = 33.1 bits (74), Expect = 0.22
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 21/138 (15%)
Query: 44 LEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEA 103
LE ++E+ R LQ KKK + ++E E L EKV E L K +E
Sbjct: 920 LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 104 LRILQ-MHC---QEKESEAQRL-----------DVRGQLEDLMGQHKDLWEFHMLEQRLA 148
IL+ +C +EK+ R+ + L L +H+ + LE+RL
Sbjct: 980 QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM--ITDLEERLR 1037
Query: 149 REIRALERSKEQLLSERR 166
RE E+ +++L RR
Sbjct: 1038 RE----EKQRQELEKTRR 1051
Score = 30.4 bits (67), Expect = 1.4
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 11/140 (7%)
Query: 38 LQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVL 97
+ KE L E ++ N L + + S+ + E L E L E + + +
Sbjct: 848 MAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLT 907
Query: 98 GKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWE-FHMLEQRLAREIRALER 156
KKQE L+ C + E+ + + R Q L + K + + LE++L E E
Sbjct: 908 AKKQE----LEEICHDLEARVEEEEERCQ--HLQAEKKKMQQNIQELEEQLEEE----ES 957
Query: 157 SKEQLLSERRLVRAKLREVE 176
++++L E+ AKL+++E
Sbjct: 958 ARQKLQLEKVTTEAKLKKLE 977
Score = 30.0 bits (66), Expect = 1.9
Identities = 45/208 (21%), Positives = 89/208 (42%), Gaps = 23/208 (11%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK 63
++ L+ + + ++ E L+T + + ++ EG L + E+ ++ + L++ K
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG-LSQRHEEKVAAYDKLEKTKT 1416
Query: 64 KSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDV 123
+ +EL + L +LD +LE KKQ+ + Q+ +EK A+ +
Sbjct: 1417 RLQQELDD-------LLVDLDHQRQSACNLE----KKQK--KFDQLLAEEKTISAKYAEE 1463
Query: 124 RGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPP 183
R + E E E + RALE + EQ RL + E+E + S
Sbjct: 1464 RDRAEA---------EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKD 1514
Query: 184 EVEGAMAVNDGLKAELEIFGEQVRSAPE 211
+V ++ + K LE E++++ E
Sbjct: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLE 1542
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 45.8 bits (107), Expect = 3e-05
Identities = 53/223 (23%), Positives = 99/223 (44%), Gaps = 32/223 (14%)
Query: 9 NVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGS----LEPQIEDLISRINDLQQAKKK 64
++ A E + A+ Q ++ E + +LQ++ + L Q +DL S++ + +A +
Sbjct: 288 SLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSR 347
Query: 65 SSEELRETHSLWEALHRELD----SLNGEKVHLEEVLGKKQEALRILQMHCQEKES---- 116
E+L+E E L +EL S K L+E+ A+ LQ Q KE
Sbjct: 348 LLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDEL------AMETLQEKSQHKEELGAV 401
Query: 117 ----EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKL 172
E + L VR + E ++L E H ++R E+R R ++ E ++ +
Sbjct: 402 RLRHEKEVLGVRARYE------RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTV 455
Query: 173 REVERRLHSPPEVEG----AMAVNDGLKAELEIFGEQVRSAPE 211
E++ ++HS +G + +G + EL+ +Q+ A E
Sbjct: 456 EELQAQVHSMDGAKGWFERRLKEAEGKEEELQDVRDQLEQAQE 498
Score = 45.4 bits (106), Expect = 4e-05
Identities = 46/164 (28%), Positives = 73/164 (44%), Gaps = 13/164 (7%)
Query: 58 LQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESE 117
L + + K E E LWE L S E L+E L K E L+ Q ++E
Sbjct: 136 LAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTE 195
Query: 118 AQRL--DVRGQLEDLM----GQHK-DLWEFHMLEQRLAREIRALERSKEQLLSERRLVRA 170
+ L D R ++E+L HK L L+Q L ++L ++Q ER A
Sbjct: 196 KETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAA 255
Query: 171 KLREVERRL-----HSPPEVEGAMAVNDGLKAELEIFGEQVRSA 209
LR ++ ++ + +VEG +A N+ L+ L EQ+++A
Sbjct: 256 ALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAAL-EQIQTA 298
Score = 38.5 bits (88), Expect = 0.005
Identities = 53/242 (21%), Positives = 102/242 (42%), Gaps = 22/242 (9%)
Query: 8 LNVEAPEATEEAEG---QAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKK 64
+++++ +A E+ EG + +L+T I+ K L E +LQQ + +
Sbjct: 264 VSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAE 323
Query: 65 SSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR 124
+ + + L L L + + L+E+ +K++ + LQ + E LD
Sbjct: 324 YEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDEL 383
Query: 125 GQLEDLM--GQHKDLW---------EFHMLEQRLAREIRAL----ERSKEQLLSERRLVR 169
+E L QHK+ E + R RE+R L +R +E+L + R +
Sbjct: 384 A-METLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEK 442
Query: 170 AKLREVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDE 229
A+ RE+E + E++ + DG K E +++ A + +L +A++E
Sbjct: 443 ARTRELETLQQTVEELQAQVHSMDGAKGWFE---RRLKEAEGKEEELQDVRDQLEQAQEE 499
Query: 230 ED 231
D
Sbjct: 500 RD 501
Score = 38.1 bits (87), Expect = 0.007
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 19/165 (11%)
Query: 22 QAKSLKTEDLLAMVIKLQKEG-SLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALH 80
Q KS E+L A+ ++ +KE + + E + +L + KK+ EELR +A
Sbjct: 389 QEKSQHKEELGAVRLRHEKEVLGVRARYE---RELRELHEDKKRQEEELRGQIREEKART 445
Query: 81 RELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRL-DVRGQLEDLMGQHKDLWE 139
REL++L L+ + A + +E E + + L DVR QLE Q ++ +
Sbjct: 446 RELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEGKEEELQDVRDQLE----QAQEERD 501
Query: 140 FHMLEQRLAREIRALERSKEQLLSERRLVRAK----LREVERRLH 180
H+ + I +L++ + + +R++ K L++++R+LH
Sbjct: 502 CHL------KTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLH 540
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 45.8 bits (107), Expect = 3e-05
Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 18/216 (8%)
Query: 10 VEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEEL 69
VE T + Q K ++ +++ +L+ E SL+ ED++ I +++ K EL
Sbjct: 1377 VEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHH-EDIVDEIECIEKTLLKRRSEL 1435
Query: 70 RETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR----- 124
RE L EL + + E + +L + +E E AQ V
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 125 GQLEDLMGQHKDLWEFHMLEQRLAREI-----------RALERSKEQLLSERRLVRAKLR 173
QL L KDL + + ++ + +EI + L + KE+L E + ++ +
Sbjct: 1496 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE 1555
Query: 174 EVERRL-HSPPEVEGAMAVNDGLKAELEIFGEQVRS 208
ER H ++ + + +AELE QV S
Sbjct: 1556 MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTS 1591
Score = 39.3 bits (90), Expect = 0.003
Identities = 50/213 (23%), Positives = 101/213 (47%), Gaps = 24/213 (11%)
Query: 1 MAGKLKPLN-----VEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRI 55
+AGK K + +++ ++ + K+ K+ + I ++ LE ++++++SRI
Sbjct: 526 IAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRI 585
Query: 56 NDLQQAKKKSSEELRETH-SLWEALHRELDS-LNGEKVHLEEVLGKKQEALRILQMHCQE 113
+ K E+L E + EAL ++L+ ++G + +L + G+ +A + E
Sbjct: 586 AKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDE 645
Query: 114 KESEAQRLDVRGQLEDLMGQHKDLWEFHMLE-QRLAREIRALERSKEQLLSERRLVRAKL 172
KE+ QRL + Q +D E ++ + + +E+ LE + L E+ V A L
Sbjct: 646 KETLLQRLTE-------VEQERDQLEIVAMDAENMRKELAELESA----LQEQHEVNASL 694
Query: 173 REVERRLHS-PPEVEGAMAVNDG----LKAELE 200
++ + L + E+E + + D LK ELE
Sbjct: 695 QQTQGDLSAYEAELEARLNLRDAEANQLKEELE 727
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 45 EPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEAL 104
+ Q+ L + DL+Q K K E L+E + + A + L+ +K L E L K Q+ +
Sbjct: 1495 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1554
Query: 105 RILQM----HCQE-KESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKE 159
+ + H Q KESE R +LE L Q +Q +A R L KE
Sbjct: 1555 EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQ------VTSQQQEMAVLDRQLGHKKE 1608
Query: 160 QL-LSERRLVRAK 171
+L L + +V+AK
Sbjct: 1609 ELHLLQGSMVQAK 1621
Score = 37.0 bits (84), Expect = 0.015
Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 15/128 (11%)
Query: 48 IEDLISRINDLQQ-AKKKSSEEL------RETHSLWEALHRELDSLNGEKVHLEEVLGKK 100
+E+ +SR+ D+ Q K K EE R++ E LH +D L EK LE +
Sbjct: 1321 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLE---CEV 1377
Query: 101 QEALRILQMHCQEK---ESEAQRLDVRGQLEDLMGQHKDLW-EFHMLEQRLAREIRALER 156
+E R +Q Q+K + + L ++E + H+D+ E +E+ L + R+ R
Sbjct: 1378 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKR-RSELR 1436
Query: 157 SKEQLLSE 164
++LL+E
Sbjct: 1437 EADRLLAE 1444
Score = 37.0 bits (84), Expect = 0.015
Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 33/210 (15%)
Query: 15 ATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHS 74
A ++++ Q S K E L + KLQK+ + + ED Q K+S L+ +
Sbjct: 1527 AAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNED------HHLQVLKESEVLLQAKRA 1580
Query: 75 LWEALHRELDSLNGEKVHLEEVLGKKQEALRILQ---MHCQEKESEAQRL---------- 121
E L ++ S E L+ LG K+E L +LQ + + EA RL
Sbjct: 1581 ELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCN 1640
Query: 122 ---DVRGQLEDLMGQHKDL--------WEFHMLEQRLAREIRALERSKEQLLSERRLVRA 170
+V+ LE+L Q +L + +++Q + +E L+ Q+ + ++
Sbjct: 1641 HIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKN 1700
Query: 171 KLREVERRLHSPPEVEGAMAVNDGLKAELE 200
L ++ H E++G +D +ELE
Sbjct: 1701 ILDMLQLENH---ELQGLKLQHDQRVSELE 1727
Score = 33.1 bits (74), Expect = 0.22
Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 15/166 (9%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLW 76
E+ KS K E+ K Q E ++E+L I+DL Q KK E+ E H
Sbjct: 1329 EDIMQHLKSKKREERWMRASKRQSE----KEMEELHHNIDDLLQEKKSLECEVEELHRTV 1384
Query: 77 EALHRELDSLNGE----KVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMG 132
+ ++ D ++G LE K + ++ C EK +R ++R + + L+
Sbjct: 1385 QKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELR-EADRLLA 1443
Query: 133 QHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
+ + E +++ + +K LL + E+ERR
Sbjct: 1444 EAES--ELSCTKEKTKNAVEKFTDAKRSLLQ----TESDAEELERR 1483
Score = 33.1 bits (74), Expect = 0.22
Identities = 39/171 (22%), Positives = 80/171 (46%), Gaps = 10/171 (5%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLW 76
E E Q L+ + ++ + K Q LE ++E + +LQQ ++ E+ L
Sbjct: 1708 ENHELQGLKLQHDQRVSELEKTQV-AVLEEKLE-----LENLQQISQQQKGEIEWQKQLL 1761
Query: 77 EALHRELDSLNGEKVHLE---EVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQ 133
E RE++ + E L+ E L K++E L+ ++K ++ +R+ + M Q
Sbjct: 1762 ERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQ 1821
Query: 134 HKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPE 184
+L + + ++L +E+ L R K L ++ ++ +L+E ++S E
Sbjct: 1822 -SNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQE 1871
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.4 bits (106), Expect = 4e-05
Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 14/182 (7%)
Query: 57 DLQQAKKKSSEELRETHSL--WEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEK 114
+LQQ +++ E RE WE +R+ D L E+ E++L +++E R+ + Q +
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE---EQLLREEREKRRLQERERQYR 1051
Query: 115 ESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLRE 174
E E +++ + E L+G+ ++ LE++ +E L++ +EQLL E R + +E
Sbjct: 1052 EEE----ELQQEEEQLLGEERETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRR-QE 1105
Query: 175 VERRLHSPPEV---EGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEED 231
ER+ E+ E + + K + Q R EV E + E P R ++
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 232 PE 233
E
Sbjct: 1166 LE 1167
Score = 38.5 bits (88), Expect = 0.005
Identities = 56/226 (24%), Positives = 99/226 (43%), Gaps = 20/226 (8%)
Query: 8 LNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSE 67
L +E E E+ E + + L+ E +L+++ E +++ + L++ +++ E
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEE-EERLQQRLRSEQQLRREQEERRE 547
Query: 68 EL--RETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRG 125
+L RE E RE L E+ + L K++E R ++ K + +RL+ R
Sbjct: 548 QLLKREEEKRLEQERRE-QRLKREQEERRDQLLKREEERRQQRL----KREQEERLEQRL 602
Query: 126 QLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLS----ERRLVRAKLREVERRLHS 181
+ E++ + L + EQRL RE ER ++ L S ERR + + + ERR
Sbjct: 603 KREEV----ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658
Query: 182 PPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRAR 227
E + LK E E+ R E+ E E E ++R
Sbjct: 659 LKREEEEERLEQRLKRE----HEEERREQELAEEEQEQARERIKSR 700
Score = 36.6 bits (83), Expect = 0.020
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 20/144 (13%)
Query: 39 QKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLG 98
+K+ Q E+ R L++ +++ +E RE + L RE + +++ +E
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERRE-----QQLRREQEERREQRLKRQEEEE 526
Query: 99 KKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSK 158
+ Q+ LR Q +E+E ++L R + + L + + EQRL RE E +
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR--------EQRLKRE---QEERR 575
Query: 159 EQLL---SERRLVRAKLREVERRL 179
+QLL ERR R K RE E RL
Sbjct: 576 DQLLKREEERRQQRLK-REQEERL 598
Score = 33.9 bits (76), Expect = 0.13
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 8/171 (4%)
Query: 37 KLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEV 96
KLQ+E EPQ + + + +Q +K +ELR E + L + EE
Sbjct: 259 KLQEE---EPQRQRELQE--EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 97 LGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALER 156
++QE R Q +++E ++ R Q E Q + E EQ+L RE + ER
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE-QEEER 372
Query: 157 SKEQLLSERRLVRAKLREVERRLHSPPEV--EGAMAVNDGLKAELEIFGEQ 205
++QL E++L R + E++L ++ E + L+ E ++ EQ
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Score = 33.9 bits (76), Expect = 0.13
Identities = 42/168 (25%), Positives = 79/168 (47%), Gaps = 15/168 (8%)
Query: 14 EATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKK-KSSEELRET 72
E E E Q + + E+ ++ ++E E + E + R L++ ++ + ++LR
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQE---EERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 73 HSLW--EALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDL 130
L + L RE +++ E+ L ++QE R Q H QE+ + + + + + L
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 131 MGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
+ ++ E H E+R + L+R +E+ ERR KL E ERR
Sbjct: 459 --KREEETERHEQERRK----QQLKRDQEE---ERRERWLKLEEEERR 497
Score = 32.3 bits (72), Expect = 0.38
Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 22/235 (9%)
Query: 17 EEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAK----KKSSEELR-- 70
E+ + + L+ E L +L++E L + E+ Q+ + K+ EE R
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 71 ----------ETHSLWEALHRELDSLNGEK-VHLEEVLGKKQEALRILQMHCQEKESEAQ 119
E + L R+ + E+ + LEE ++Q+ R Q+ +++E Q
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 120 RLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLL-SERRLVRAKLREVERR 178
RL + Q E+ Q + E + ++ R + L+R +E+ L ERR R K + ERR
Sbjct: 518 RL--KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 179 LHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPE 233
E LK E E EQ EV E E E R+E + E
Sbjct: 576 DQLLKREEERR--QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Score = 31.6 bits (70), Expect = 0.65
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 15/153 (9%)
Query: 47 QIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRI 106
Q+E+ R AK E+LR+ L + EL EK +E + +E ++
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 107 LQMHCQ--EKESEAQRLDVRGQL-----------EDLMGQHKDLWEFHMLEQRLAREIRA 153
Q Q +E E +R R + E L+G+ + E++ RE
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY-REEEE 995
Query: 154 LERSKEQLLSERRLVRAKLREVERRLHSPPEVE 186
L++ +EQLL E R R + +E ER+ E++
Sbjct: 996 LQQEEEQLLREEREKRRR-QEWERQYRKKDELQ 1027
Score = 30.0 bits (66), Expect = 1.9
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 39 QKEGSLEPQIEDLISRINDL--QQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEV 96
++E L+ + E L+ + Q+ +++ EE + +R+ D + K E
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP- 1229
Query: 97 LGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAR----EIR 152
+K+ A+R +++C+ +E+E R QL D Q +DL H+L ++ R E R
Sbjct: 1230 --EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQ--HLLGEQQERDREQERR 1284
Query: 153 ALERSKEQLLSERRLVRAKLREVERR 178
++ E +L R + +E +RR
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRR 1310
Score = 28.1 bits (61), Expect = 7.2
Identities = 33/156 (21%), Positives = 64/156 (41%), Gaps = 12/156 (7%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLW- 76
E E + + LK E + +L++E ++E L Q+ K++ EE R L
Sbjct: 582 EEERRQQRLKREQEERLEQRLKRE-----EVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 77 -EALHRELDSLNGEKVHLEEVLGKKQEA-----LRILQMHCQEKESEAQRLDVRGQLEDL 130
E R L E+ E K++E R+ + H +E+ + + + Q +
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 131 MGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERR 166
+ W++ + + AR+ + R ++Q RR
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Score = 28.1 bits (61), Expect = 7.2
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 94 EEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRA 153
EE L +++ A ++ QE+E Q R + ++ K W+ +R + A
Sbjct: 837 EEQLQRRERAQQL-----QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 154 LERSKEQLLSERRLVRAKLREVER 177
+EQL E++L++ + E++R
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQR 915
Score = 28.1 bits (61), Expect = 7.2
Identities = 42/194 (21%), Positives = 79/194 (40%), Gaps = 30/194 (15%)
Query: 11 EAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELR 70
E E E+ E + + K+++ ++ + ++E + + L Q +++ +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 71 ETHSLW---EALHRELDSLNGEKVHLEEVLGKKQEALRIL-----QMHCQEKESEAQR-- 120
E + E H+E G K EE ++QE R Q+ CQE+E + ++
Sbjct: 1357 ERDRKFREEELRHQE----QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 121 -LDVRGQLEDLMGQHKDLW---------------EFHMLEQRLAREIRALERSKEQLLSE 164
R + + L Q +D +F EQ+L +E R +EQLL E
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 165 RRLVRAKLREVERR 178
R + +E +R+
Sbjct: 1473 REEQQLHRQERDRK 1486
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 4e-05
Identities = 42/220 (19%), Positives = 98/220 (44%), Gaps = 24/220 (10%)
Query: 1 MAGKLKPLNVEAPEATE---EAEGQAKSLKT----------------EDLLAMVIKLQKE 41
M G L + ++ A EA+ Q KSL++ +DL + +++
Sbjct: 1620 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1679
Query: 42 GSL-EPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKK 100
+L + ++E+L + + ++++K + +EL ET + LH + SL +K +E L +
Sbjct: 1680 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQL 1739
Query: 101 QEALRILQMHCQEKESEAQR--LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSK 158
Q + C+ E +A++ D E+L + +++ + + I+ L+
Sbjct: 1740 QSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1799
Query: 159 EQLLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAE 198
++ +E+ ++ +++++ E+EG + AE
Sbjct: 1800 DE--AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAE 1837
Score = 36.6 bits (83), Expect = 0.020
Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 31/214 (14%)
Query: 14 EATEEAEGQA-KSLKTEDLLAMVIKLQKEGSLEPQIEDLISRIN-------DLQQAKKKS 65
+A +EA QA L+ E+ + K LE Q++DL + DL++AK+K
Sbjct: 999 KALQEAHQQALDDLQVEEDKVNSLSKSKV-KLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1057
Query: 66 SEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRG 125
+L+ T + L +K+ LEE L KK+ I Q + + ++ + L ++
Sbjct: 1058 EGDLKLTQE-------SIMDLENDKLQLEEKLKKKE--FDINQQNSKIEDEQVLALQLQK 1108
Query: 126 QLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEV 185
+L++ + ++L E E+ A ++ ++ R + +L E+ RL E
Sbjct: 1109 KLKENQARIEELEE----------ELEAERTARAKVEKLRSDLSRELEEISERLE---EA 1155
Query: 186 EGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEA 219
GA +V + + E +++R E + EA
Sbjct: 1156 GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1189
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 45.4 bits (106), Expect = 4e-05
Identities = 46/164 (28%), Positives = 73/164 (44%), Gaps = 13/164 (7%)
Query: 58 LQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESE 117
L + + K E E LWE L S E L+E L K E L+ Q ++E
Sbjct: 189 LAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTE 248
Query: 118 AQRL--DVRGQLEDLM----GQHK-DLWEFHMLEQRLAREIRALERSKEQLLSERRLVRA 170
+ L D R ++E+L HK L L+Q L ++L ++Q ER A
Sbjct: 249 KETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAA 308
Query: 171 KLREVERRL-----HSPPEVEGAMAVNDGLKAELEIFGEQVRSA 209
LR ++ ++ + +VEG +A N+ L+ L EQ+++A
Sbjct: 309 ALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAAL-EQIQTA 351
Score = 42.7 bits (99), Expect = 3e-04
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 28/195 (14%)
Query: 9 NVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGS----LEPQIEDLISRINDLQQAKKK 64
++ A E + A+ Q ++ E + +LQ++ + L Q +DL S++ + +A +
Sbjct: 341 SLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSR 400
Query: 65 SSEELRETHSLWEALHRELD----SLNGEKVHLEEVLGKKQEALRILQMHCQEKES---- 116
E+L+E E L +EL S K L+E+ A+ LQ Q KE
Sbjct: 401 LLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDEL------AMETLQEKSQHKEELGAV 454
Query: 117 ----EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKL 172
E + L VR + E ++L E H ++R E+R R ++ E ++ +
Sbjct: 455 RLRHEKEVLGVRARYE------RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTV 508
Query: 173 REVERRLHSPPEVEG 187
E++ ++HS +G
Sbjct: 509 EELQAQVHSMDGAKG 523
Score = 39.3 bits (90), Expect = 0.003
Identities = 50/193 (25%), Positives = 87/193 (45%), Gaps = 22/193 (11%)
Query: 4 KLKPLNVEAPEATE-EAEGQAKSLKTEDLLAMVIKL--QKEGSLEPQIEDLISRINDLQQ 60
K + LN+ + T AE Q + + EDL+ L Q + SL L+ ++ ++ Q
Sbjct: 352 KTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSR-LLEQLQEIGQ 410
Query: 61 AKKKSSEELRETHSLWEALHRELDSLNGEKV-----HLEEV----LGKKQEALRILQMHC 111
K++ ++EL+E E LD L E + H EE+ L ++E L + +
Sbjct: 411 EKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARY- 469
Query: 112 QEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAK 171
E+E D + Q E+L GQ ++ E+ RE+ L+++ E+L ++ +
Sbjct: 470 -ERELRELHEDKKRQEEELRGQIRE-------EKARTRELETLQQTVEELQAQVHSMDGA 521
Query: 172 LREVERRLHSPPE 184
ERRL E
Sbjct: 522 KGWFERRLKEAEE 534
Score = 37.7 bits (86), Expect = 0.009
Identities = 48/211 (22%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 8 LNVEAPEATEEAEG---QAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKK 64
+++++ +A E+ EG + +L+T I+ K L E +LQQ + +
Sbjct: 317 VSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAE 376
Query: 65 SSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVR 124
+ + + L L L + + L+E+ +K++ + LQ + E LD
Sbjct: 377 YEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDEL 436
Query: 125 GQLEDLM--GQHKDLW---------EFHMLEQRLAREIRAL----ERSKEQLLSERRLVR 169
+E L QHK+ E + R RE+R L +R +E+L + R +
Sbjct: 437 A-METLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEK 495
Query: 170 AKLREVERRLHSPPEVEGAMAVNDGLKAELE 200
A+ RE+E + E++ + DG K E
Sbjct: 496 ARTRELETLQQTVEELQAQVHSMDGAKGWFE 526
Score = 35.8 bits (81), Expect = 0.034
Identities = 42/181 (23%), Positives = 84/181 (46%), Gaps = 25/181 (13%)
Query: 22 QAKSLKTEDLLAMVIKLQKEG-SLEPQIEDLISRINDLQQAKKKSSEEL----------- 69
Q KS E+L A+ ++ +KE + + E + +L + KK+ EEL
Sbjct: 442 QEKSQHKEELGAVRLRHEKEVLGVRARYE---RELRELHEDKKRQEEELRGQIREEKART 498
Query: 70 RETHSLW---EALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE---KESEAQRLDV 123
RE +L E L ++ S++G K E L + +E+L+ Q +E + E ++
Sbjct: 499 RELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAEL 558
Query: 124 RGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAK----LREVERRL 179
+G+ E+L L + + I +L++ + + +R++ K L++++R+L
Sbjct: 559 KGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQL 618
Query: 180 H 180
H
Sbjct: 619 H 619
Score = 33.5 bits (75), Expect = 0.17
Identities = 41/186 (22%), Positives = 82/186 (44%), Gaps = 17/186 (9%)
Query: 4 KLKPLNVEAPEATEEAEGQAKSLKTE----DLLAMVIKLQKEGSLEPQIEDLISRINDLQ 59
+L+ + E + T+E + KS + D LAM +K E + ++
Sbjct: 404 QLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVL 463
Query: 60 QAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQ 119
+ + ELRE H E R+ + L G+ + E + +E L LQ +E +++
Sbjct: 464 GVRARYERELRELH---EDKKRQEEELRGQ---IREEKARTRE-LETLQQTVEELQAQVH 516
Query: 120 RLD-VRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
+D +G E + + ++ L+Q+ + AL++ +EQ +E + +L++V +
Sbjct: 517 SMDGAKGWFERRLKEAEE-----SLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQ 571
Query: 179 LHSPPE 184
L E
Sbjct: 572 LEQAQE 577
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.1 bits (105), Expect = 6e-05
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 12/152 (7%)
Query: 39 QKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSL---NGEKVHLEE 95
Q EG + E L R L Q +K +++ ++ WE + RE + L G+ ++
Sbjct: 1632 QAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKN 1691
Query: 96 VLGKKQEAL--RILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRA 153
+L +K E L R + QEKE + ++ +E+L + ++L + E +L E +
Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEEL---NQEEGKLVEEKKK 1748
Query: 154 LERSKEQLLSERRLVRAKLREVERRLHSPPEV 185
L +E L +R KL E E +L E+
Sbjct: 1749 LAEEEEALAWQRE----KLSEEETKLAQEEEL 1776
Score = 38.1 bits (87), Expect = 0.007
Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Query: 29 EDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNG 88
E + V +++ E ++E L+ + + + EE E E RE +
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK 2270
Query: 89 EKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQ--------HKDLWEF 140
E+ EE +K+E + + ++KE ++ +V + E++M + ++ E
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Query: 141 HMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRL 179
LE+ + RE L++ K+ L E+R R LR ER L
Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQR--RKSLRGRERVL 2367
Score = 36.2 bits (82), Expect = 0.026
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 14/187 (7%)
Query: 29 EDLLAMVIKLQK-EGSLEPQIEDLISRIND-LQQAKKKSSEELRETHSLWEALHRELDSL 86
E++L+ K Q+ + E +E+ +SR + +Q + ++E H W +HR+
Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK-WARIHRKRARA 1584
Query: 87 NGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDL-MGQHKDLWEFHMLEQ 145
++ E L +++E L + ++E + + V+ +D M Q + +F E+
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEG--KFAQKEE 1642
Query: 146 RLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELE-IFGE 204
LA+ L + E+L +R+ + K +V R E +A G AE++ I +
Sbjct: 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWEKVARE-------EEKLAKKGGKLAEVKNILAQ 1695
Query: 205 QVRSAPE 211
+V P+
Sbjct: 1696 KVEELPQ 1702
Score = 35.8 bits (81), Expect = 0.034
Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 16/173 (9%)
Query: 11 EAPEATEEAEGQAKSL--KTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEE 68
E + EE E + L K E+L Q+EG L + + L L ++K SEE
Sbjct: 1713 ELAQELEELEWDMEELSWKEEELN------QEEGKLVEEKKKLAEEEEALAWQREKLSEE 1766
Query: 69 LRETHSLWEALHRELDSLNGEKVHL---EEVLGKKQEALRILQMH-CQEKESEAQRLDVR 124
+ E L +E + L K + EE LG+K+E L +M Q++E ++
Sbjct: 1767 ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Query: 125 GQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLL-SERRLVRAKLREVE 176
+ + ++ Q K+L + ++ LA+E L + KE LL ++ RL +K + V+
Sbjct: 1827 TKNKMILYQKKNLAQ---EKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 45.1 bits (105), Expect = 6e-05
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 26/214 (12%)
Query: 25 SLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELD 84
SL E+ LA VI+LQ ++IS+ + Q K E L S L +LD
Sbjct: 242 SLSHEEDLAKVIELQ----------EIISKQSREQSQMK---ERLASLSSHVTELEEDLD 288
Query: 85 SLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLE 144
+ + + EE+ K Q +R ++ E L+ R + ++ H L
Sbjct: 289 TARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKR-----YLAAQREATSVHDLN 343
Query: 145 QRLAREI-------RALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLK 196
+L EI R E QL L KL++ R+ + PEVE +A L
Sbjct: 344 DKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALS 403
Query: 197 AELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
E G ++ A E EL RAR E
Sbjct: 404 KAEERHGNIEERLRQMEAQLEEKNQELQRARQRE 437
Score = 39.7 bits (91), Expect = 0.002
Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 9/178 (5%)
Query: 1 MAGKLKPLNVEAPEATEEAEGQAKSL-KTEDLLAMVIKLQKE-GSLEPQIEDLISRINDL 58
M +L L+ E E+ + K L K+E+ M KLQ++ Q ED+ RI L
Sbjct: 269 MKERLASLSSHVTELEEDLDTARKDLIKSEE---MNTKLQRDVREAMAQKEDMEERITTL 325
Query: 59 QQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEA 118
++ + E H L + L E+ + + E+ + QE L + + Q+ +A
Sbjct: 326 EKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKA 385
Query: 119 QRL-DVRGQLEDLMGQHKDLWEFH-MLEQRLAREIRALERSKEQLLSERRLVRAKLRE 174
+ L +V +L + E H +E+RL + LE ++L +R R K+ E
Sbjct: 386 ETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQEL--QRARQREKMNE 441
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 45.1 bits (105), Expect = 6e-05
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 26/214 (12%)
Query: 25 SLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELD 84
SL E+ LA VI+LQ ++IS+ + Q K E L S L +LD
Sbjct: 242 SLSHEEDLAKVIELQ----------EIISKQSREQSQMK---ERLASLSSHVTELEEDLD 288
Query: 85 SLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLE 144
+ + + EE+ K Q +R ++ E L+ R + ++ H L
Sbjct: 289 TARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKR-----YLAAQREATSVHDLN 343
Query: 145 QRLAREI-------RALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVN-DGLK 196
+L EI R E QL L KL++ R+ + PEVE +A L
Sbjct: 344 DKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALS 403
Query: 197 AELEIFGEQVRSAPEVGAGEGEAGPELPRARDEE 230
E G ++ A E EL RAR E
Sbjct: 404 KAEERHGNIEERLRQMEAQLEEKNQELQRARQRE 437
Score = 39.7 bits (91), Expect = 0.002
Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 9/178 (5%)
Query: 1 MAGKLKPLNVEAPEATEEAEGQAKSL-KTEDLLAMVIKLQKE-GSLEPQIEDLISRINDL 58
M +L L+ E E+ + K L K+E+ M KLQ++ Q ED+ RI L
Sbjct: 269 MKERLASLSSHVTELEEDLDTARKDLIKSEE---MNTKLQRDVREAMAQKEDMEERITTL 325
Query: 59 QQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEA 118
++ + E H L + L E+ + + E+ + QE L + + Q+ +A
Sbjct: 326 EKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKA 385
Query: 119 QRL-DVRGQLEDLMGQHKDLWEFH-MLEQRLAREIRALERSKEQLLSERRLVRAKLRE 174
+ L +V +L + E H +E+RL + LE ++L +R R K+ E
Sbjct: 386 ETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQEL--QRARQREKMNE 441
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 45.1 bits (105), Expect = 6e-05
Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 31/239 (12%)
Query: 15 ATEEAEGQAKSLKTE-DLLAMVIKLQKEGSLEPQI-EDLISRINDLQQAKKKSSEELRET 72
A AE +A++++ E D+ A+ +L ++ S + + +++L + + S++L +
Sbjct: 108 AARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQA 167
Query: 73 HSLWEALHRELDSLNGE-----------KVHLEEVLGKKQEALRILQMHCQEKESEAQRL 121
+ L RELD+L G+ + LE + G+ Q +LQ Q+ E++
Sbjct: 168 SQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQ----MLQSRRQDLEAQ---- 219
Query: 122 DVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHS 181
+RG E++ L H L RE R E+ SE + LR ++RR+
Sbjct: 220 -IRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRV-- 276
Query: 182 PPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGP------ELPRARDEEDPEP 234
E+E + D + + E S + G+G P P+ R P+P
Sbjct: 277 -SELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQP 334
>gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo
sapiens]
Length = 805
Score = 44.7 bits (104), Expect = 7e-05
Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 25/148 (16%)
Query: 39 QKEGSLEPQIEDLISRI----NDLQQAKKKSSEELRETHSLW---EALHRELDSLNGEKV 91
+K L I DL SRI + L+ A++K +E L + L R+L++ + + +
Sbjct: 598 RKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNI 657
Query: 92 HLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREI 151
+V+ K++EA+ Q+ +EK E L LE +
Sbjct: 658 EFLQVIAKREEAIHQSQLRLEEKTRECGTL------------------ARQLESAIEDAR 699
Query: 152 RALERSKEQLLSERRLVRAKLREVERRL 179
R +E++KE LS+ R + K+ ++E +L
Sbjct: 700 RQVEQTKEHALSKERAAQNKILDLETQL 727
Score = 35.8 bits (81), Expect = 0.034
Identities = 40/180 (22%), Positives = 79/180 (43%), Gaps = 19/180 (10%)
Query: 18 EAEGQAKSLKTEDLLAMVIKLQKE--------GSLEPQIEDLISRINDLQQAKKKSSEEL 69
E +G A + + L + KL+ E +L Q E L+ +++ ++ + + L
Sbjct: 191 EMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLL 250
Query: 70 RETHSLWE---------ALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQR 120
RE H + AL + L + EK L +L K + + L Q ++++A+
Sbjct: 251 REQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKT 310
Query: 121 L-DVRGQLEDLMGQ-HKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERR 178
++ +E + G L RL +I+ LERS Q +E + +L+E++++
Sbjct: 311 ASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQK 370
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/231 (20%), Positives = 102/231 (44%), Gaps = 31/231 (13%)
Query: 1 MAGKLKPLNVEAPEATE---EAEGQAKSLKT----------------EDLLAMVIKLQKE 41
M G L + ++ A EA+ Q KSL++ +DL + +++
Sbjct: 1618 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1677
Query: 42 GSL-EPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKK 100
+L + ++E+L + + ++++K + +EL ET + LH + SL +K ++ L +
Sbjct: 1678 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQL 1737
Query: 101 QEALRILQMHCQEKESEAQR--LDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALER-- 156
Q + C+ E +A++ D E+L + +++ + + I+ L+
Sbjct: 1738 QTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797
Query: 157 -SKEQLL-----SERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELEI 201
EQ+ + + + A++RE+E L + + A +V K+E I
Sbjct: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEA-EQKRNAESVKGMRKSERRI 1847
Score = 30.8 bits (68), Expect = 1.1
Identities = 41/190 (21%), Positives = 79/190 (41%), Gaps = 20/190 (10%)
Query: 6 KPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEP---QIEDLISRINDLQQAK 62
K + ++ A + EG K + + K Q + L+ ++ L +RI D Q
Sbjct: 1042 KKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALG 1101
Query: 63 KKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQE--------- 113
+ ++L+E + E L EL++ + +E++ L + +E
Sbjct: 1102 SQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1161
Query: 114 ---KESEAQRLDVRGQLEDLMGQHK----DLWEFHM-LEQRLAREIRALERSKEQLLSER 165
K+ EA+ +R LE+ QH+ L + H L +I L+R K++L E+
Sbjct: 1162 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1221
Query: 166 RLVRAKLREV 175
+ +L +V
Sbjct: 1222 SEFKLELDDV 1231
Score = 30.4 bits (67), Expect = 1.4
Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 31/188 (16%)
Query: 5 LKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKK 64
L V+ + ++ EG + K + K + EG L+ E ++ ND QQ ++
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 65 SSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKK-QEALRILQMHCQEKESEAQ---- 119
++ EL++LN ++ E+ LG + Q+ L+ LQ +E E E +
Sbjct: 1080 LKKK-----------DFELNALNA-RIEDEQALGSQLQKKLKELQARIEELEEELEAERT 1127
Query: 120 --------RLDVRGQLEDLMGQHKDLW-----EFHMLEQRLAREIRALERSKEQLLSERR 166
R D+ +LE++ + ++ + M ++R A E + + R E+ +
Sbjct: 1128 ARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA-EFQKMRRDLEEATLQHE 1186
Query: 167 LVRAKLRE 174
A LR+
Sbjct: 1187 ATAAALRK 1194
Score = 28.9 bits (63), Expect = 4.2
Identities = 28/126 (22%), Positives = 57/126 (45%), Gaps = 17/126 (13%)
Query: 43 SLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQE 102
S + + L + + L+ A ++S E L E RE +L E L E LG +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHL-------ETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 103 ALRILQMHCQEKESEAQRLDVRGQLEDLMG--QHKD------LWEFHMLEQRLAREIRAL 154
+ L+ K+ EA++++++ LE+ +H++ EF+ ++ + R++
Sbjct: 1522 TIHELEK--VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Query: 155 ERSKEQ 160
+ EQ
Sbjct: 1580 DEEMEQ 1585
Score = 28.5 bits (62), Expect = 5.5
Identities = 41/179 (22%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 6 KPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKE-GSLEPQIED---LISRIN----- 56
+ L + E +AE +S+ DL + KLQ E G L Q+++ LIS++
Sbjct: 1250 RTLEDQMNEHRSKAEETQRSVN--DLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLT 1307
Query: 57 ---DLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRIL------ 107
L+ K++ EE++ ++L AL + + EE K E R+L
Sbjct: 1308 YTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367
Query: 108 --QMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSE 164
Q + + QR + + + + Q L E + + + +LE++K +L +E
Sbjct: 1368 VAQWRTKYETDAIQRTEELEEAKKKLAQR--LQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 44.3 bits (103), Expect = 1e-04
Identities = 63/299 (21%), Positives = 114/299 (38%), Gaps = 79/299 (26%)
Query: 12 APEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEEL-- 69
A + EE +G ++L+ E Q++ + + E L R+ ++ +A+ ++ E+
Sbjct: 2354 AQQLAEETQGFQRTLEAER--------QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 70 --RETHSLWEALHRELDSLNGEKVHLEEVLG-----------KKQEALRILQMHCQEKES 116
++ + E LHR + EKV L + L + +EA+ L+ ++ +
Sbjct: 2406 FRKQAEEIGEKLHRT-ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2464
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRAL---------------------- 154
EA+ L ++ + + Q + L E L+Q E +L
Sbjct: 2465 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2524
Query: 155 ----------ERSKEQLLSERRLVRAKLREVERRLHSPPE-------------------V 185
+R ++Q+ ER+ + A + E RR H E
Sbjct: 2525 AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQE 2584
Query: 186 EGAMAVNDGLKAELEIFGEQVRSA----PEVGAGEGEAGPELPRARDEEDPEPPVAAPD 240
E N L+ +L++ EQ R+A EV A + A LP RD D A P+
Sbjct: 2585 ELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2643
Score = 42.0 bits (97), Expect = 5e-04
Identities = 56/231 (24%), Positives = 98/231 (42%), Gaps = 17/231 (7%)
Query: 10 VEAPEATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEE 68
+E + + EAE Q+K + A + + LQ+E Q+ + R Q +++ EE
Sbjct: 1567 LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1626
Query: 69 LRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLE 128
W+ E L ++ EEV +K A + +E E EA+R RG+ E
Sbjct: 1627 AERELERWQLKANEALRL---RLQAEEVAQQKSLAQAEAEKQKEEAEREARR---RGKAE 1680
Query: 129 DLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLR----EVERRL--HSP 182
+ + ++L E + +QR E A +R L +E+ L+R + E +R+L
Sbjct: 1681 EQAVRQRELAEQELEKQRQLAEGTAQQR----LAAEQELIRLRAETEQGEQQRQLLEEEL 1736
Query: 183 PEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPE 233
++ A + ELE +VR+ EV E R+ E+ +
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1787
Score = 34.3 bits (77), Expect = 0.10
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 48 IEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRIL 107
I + + R+ + ++ ++ E RE + EA + L + H + ++EA + L
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL--AEAHAQAKAQAEREA-KEL 1393
Query: 108 QMHCQEK--ESEAQRLDVRGQLEDLMGQHKDLWEFHMLE-QRLAREIRALERSKEQLLSE 164
Q QE+ E +D + Q + + + L + E Q AR+ A ERS+ ++ E
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1453
Query: 165 RRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPE 211
R+VR +L ER + GA L+A E Q R A E
Sbjct: 1454 IRVVRLQLEATER------QRGGAEGELQALRARAEEAEAQKRQAQE 1494
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 44.3 bits (103), Expect = 1e-04
Identities = 63/299 (21%), Positives = 114/299 (38%), Gaps = 79/299 (26%)
Query: 12 APEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEEL-- 69
A + EE +G ++L+ E Q++ + + E L R+ ++ +A+ ++ E+
Sbjct: 2358 AQQLAEETQGFQRTLEAER--------QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409
Query: 70 --RETHSLWEALHRELDSLNGEKVHLEEVLG-----------KKQEALRILQMHCQEKES 116
++ + E LHR + EKV L + L + +EA+ L+ ++ +
Sbjct: 2410 FRKQAEEIGEKLHRT-ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2468
Query: 117 EAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRAL---------------------- 154
EA+ L ++ + + Q + L E L+Q E +L
Sbjct: 2469 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2528
Query: 155 ----------ERSKEQLLSERRLVRAKLREVERRLHSPPE-------------------V 185
+R ++Q+ ER+ + A + E RR H E
Sbjct: 2529 AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQE 2588
Query: 186 EGAMAVNDGLKAELEIFGEQVRSA----PEVGAGEGEAGPELPRARDEEDPEPPVAAPD 240
E N L+ +L++ EQ R+A EV A + A LP RD D A P+
Sbjct: 2589 ELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2647
Score = 42.0 bits (97), Expect = 5e-04
Identities = 56/231 (24%), Positives = 98/231 (42%), Gaps = 17/231 (7%)
Query: 10 VEAPEATEEAEGQAKSLKTEDLLAMVIK-LQKEGSLEPQIEDLISRINDLQQAKKKSSEE 68
+E + + EAE Q+K + A + + LQ+E Q+ + R Q +++ EE
Sbjct: 1571 LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1630
Query: 69 LRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLE 128
W+ E L ++ EEV +K A + +E E EA+R RG+ E
Sbjct: 1631 AERELERWQLKANEALRL---RLQAEEVAQQKSLAQAEAEKQKEEAEREARR---RGKAE 1684
Query: 129 DLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLR----EVERRL--HSP 182
+ + ++L E + +QR E A +R L +E+ L+R + E +R+L
Sbjct: 1685 EQAVRQRELAEQELEKQRQLAEGTAQQR----LAAEQELIRLRAETEQGEQQRQLLEEEL 1740
Query: 183 PEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPE 233
++ A + ELE +VR+ EV E R+ E+ +
Sbjct: 1741 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1791
Score = 34.3 bits (77), Expect = 0.10
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 48 IEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRIL 107
I + + R+ + ++ ++ E RE + EA + L + H + ++EA + L
Sbjct: 1341 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL--AEAHAQAKAQAEREA-KEL 1397
Query: 108 QMHCQEK--ESEAQRLDVRGQLEDLMGQHKDLWEFHMLE-QRLAREIRALERSKEQLLSE 164
Q QE+ E +D + Q + + + L + E Q AR+ A ERS+ ++ E
Sbjct: 1398 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1457
Query: 165 RRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPE 211
R+VR +L ER + GA L+A E Q R A E
Sbjct: 1458 IRVVRLQLEATER------QRGGAEGELQALRARAEEAEAQKRQAQE 1498
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,794,615
Number of Sequences: 37866
Number of extensions: 460113
Number of successful extensions: 4228
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 595
Number of HSP's that attempted gapping in prelim test: 2864
Number of HSP's gapped (non-prelim): 1668
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.