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Search of human proteins with 193788632
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2
isoform 2 [Homo sapiens]
(568 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 1142 0.0
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 1117 0.0
gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s... 102 7e-22
gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo s... 100 4e-21
gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo sa... 78 2e-14
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 69 1e-11
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 68 2e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 68 3e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 68 3e-11
gi|148746195 trichohyalin [Homo sapiens] 67 6e-11
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 66 7e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 65 2e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 65 2e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 3e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 5e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 63 6e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 8e-10
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 63 8e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 63 8e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 63 8e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 63 8e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 63 8e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 2e-09
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 61 2e-09
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 61 2e-09
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 61 3e-09
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 60 5e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 7e-09
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 60 7e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 60 7e-09
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
[Homo sapiens]
Length = 568
Score = 1142 bits (2953), Expect = 0.0
Identities = 568/568 (100%), Positives = 568/568 (100%)
Query: 1 MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS 60
MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS
Sbjct: 1 MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS 60
Query: 61 EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP 120
EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP
Sbjct: 61 EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP 120
Query: 121 DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE 180
DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE
Sbjct: 121 DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE 180
Query: 181 VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC 240
VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC
Sbjct: 181 VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC 240
Query: 241 RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE 300
RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE
Sbjct: 241 RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE 300
Query: 301 AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC 360
AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC
Sbjct: 301 AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC 360
Query: 361 KIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGT 420
KIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGT
Sbjct: 361 KIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGT 420
Query: 421 NSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVP 480
NSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVP
Sbjct: 421 NSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVP 480
Query: 481 QADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCM 540
QADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCM
Sbjct: 481 QADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCM 540
Query: 541 KRYKELVEMVKAKKAAQEQVLNASRAKK 568
KRYKELVEMVKAKKAAQEQVLNASRAKK
Sbjct: 541 KRYKELVEMVKAKKAAQEQVLNASRAKK 568
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 1117 bits (2889), Expect = 0.0
Identities = 568/621 (91%), Positives = 568/621 (91%), Gaps = 53/621 (8%)
Query: 1 MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS 60
MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS
Sbjct: 1 MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELS 60
Query: 61 EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP 120
EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP
Sbjct: 61 EESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHP 120
Query: 121 DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE 180
DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE
Sbjct: 121 DKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFE 180
Query: 181 VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC 240
VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC
Sbjct: 181 VFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAEC 240
Query: 241 RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE 300
RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE
Sbjct: 241 RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAE 300
Query: 301 AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC 360
AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC
Sbjct: 301 AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSC 360
Query: 361 K-----------------------------------------------------IEEINE 367
K IEEINE
Sbjct: 361 KTWNHFSDNEAERVKMMEEVEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINE 420
Query: 368 QIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVI 427
QIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVI
Sbjct: 421 QIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVI 480
Query: 428 ANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATP 487
ANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATP
Sbjct: 481 ANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATP 540
Query: 488 SERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELV 547
SERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELV
Sbjct: 541 SERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELV 600
Query: 548 EMVKAKKAAQEQVLNASRAKK 568
EMVKAKKAAQEQVLNASRAKK
Sbjct: 601 EMVKAKKAAQEQVLNASRAKK 621
>gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo
sapiens]
Length = 531
Score = 102 bits (255), Expect = 7e-22
Identities = 100/415 (24%), Positives = 184/415 (44%), Gaps = 56/415 (13%)
Query: 89 HYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEML 148
HY LG VR A++ ++K A++ + LK HPDK E F I AY++L
Sbjct: 4 HYEALG---VRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAE----QFKLIQAAYDVL 56
Query: 149 SDPVKRRAFNS-----VDPTFDNSVPSKS----------------EAKDNFFEVFTPVFE 187
SDP +R +++ + FD S + + F+ V+ VFE
Sbjct: 57 SDPQERAWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFE 116
Query: 188 RNSRWSNKK-------NVPKLGDMNSSFEDV-DIFYSFWYNFDSWREFSYLDEEEKEKAE 239
++ + + P GD S ++ V FY++W +F + + F++ +E + +A
Sbjct: 117 MIAKEELESVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQAS 176
Query: 240 CRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKA 299
R E+R +EK+N+ R + +KE+ +R LV D R++ ++ + ++ AEK KA
Sbjct: 177 NRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVE-EQNAEKARKA 235
Query: 300 EAKRKEQEAKEK------QRQAELEAARLAKEKEEEEVRQQALL--AKKEKDIQKKAIKK 351
E R++Q+ K+ + Q+ + A L KE +E E R + E ++++ +K
Sbjct: 236 EEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKD 295
Query: 352 ERQ-KLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLI 410
E K + + E+ + + + + +A KN EKS ++ L+
Sbjct: 296 EEDGKDSDEAEDAELYDDLYCPACDKSFKTEKAMKNHEKSK----------KHREMVALL 345
Query: 411 KAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDIN 465
K SR ++ N ++ +S ++ K + K + +K P Q D N
Sbjct: 346 KQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLSKKQKKKKQKPAQNYDDN 400
>gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo
sapiens]
Length = 576
Score = 100 bits (249), Expect = 4e-21
Identities = 98/410 (23%), Positives = 182/410 (44%), Gaps = 56/410 (13%)
Query: 89 HYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEML 148
HY LG VR A++ ++K A++ + LK HPDK E F I AY++L
Sbjct: 4 HYEALG---VRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAE----QFKLIQAAYDVL 56
Query: 149 SDPVKRRAFNS-----VDPTFDNSVPSKS----------------EAKDNFFEVFTPVFE 187
SDP +R +++ + FD S + + F+ V+ VFE
Sbjct: 57 SDPQERAWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFE 116
Query: 188 RNSRWSNKK-------NVPKLGDMNSSFEDV-DIFYSFWYNFDSWREFSYLDEEEKEKAE 239
++ + + P GD S ++ V FY++W +F + + F++ +E + +A
Sbjct: 117 MIAKEELESVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQAS 176
Query: 240 CRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKA 299
R E+R +EK+N+ R + +KE+ +R LV D R++ ++ + ++ AEK KA
Sbjct: 177 NRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVE-EQNAEKARKA 235
Query: 300 EAKRKEQEAKEK------QRQAELEAARLAKEKEEEEVRQQALL--AKKEKDIQKKAIKK 351
E R++Q+ K+ + Q+ + A L KE +E E R + E ++++ +K
Sbjct: 236 EEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKD 295
Query: 352 ERQ-KLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLI 410
E K + + E+ + + + + +A KN EKS ++ L+
Sbjct: 296 EEDGKDSDEAEDAELYDDLYCPACDKSFKTEKAMKNHEKSK----------KHREMVALL 345
Query: 411 KAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQ 460
K SR ++ N ++ +S ++ K + K + +K P Q
Sbjct: 346 KQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLSKKQKKKKQKPAQ 395
>gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo
sapiens]
Length = 554
Score = 77.8 bits (190), Expect = 2e-14
Identities = 42/110 (38%), Positives = 67/110 (60%), Gaps = 1/110 (0%)
Query: 449 KAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATP-SERFEGPYTDFTPWTTEEQK 507
+ K + L+ K + +K+ K +K+ + Q +++ S R E + PWT +QK
Sbjct: 444 RRKPARLLEATAKPEPEEKSRAKRQKDFDIAEQNESSDEESLRKERARSAEEPWTQNQQK 503
Query: 508 LLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQ 557
LLE AL+ YP + +RW+KIA VP ++K+DC+ RYK LVE+V+ KK A+
Sbjct: 504 LLELALQQYPRGSSDRWDKIARCVPSKSKEDCIARYKLLVELVQKKKQAK 553
Score = 49.7 bits (117), Expect = 7e-06
Identities = 82/366 (22%), Positives = 135/366 (36%), Gaps = 58/366 (15%)
Query: 90 YAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLS 149
Y LG V+ A+ I+ A++ + L HPDK K E F + YE+L
Sbjct: 67 YQFLG---VQQDASSADIRKAYRKLSLTLHPDKNK------DENAETQFRQLVAIYEVLK 117
Query: 150 DPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFE-RNSRWSNKKNVPKLGDMNSSF 208
D +R+ ++ + N +P + PVF R R + + L + +
Sbjct: 118 DDERRQRYDDI---LINGLPDWRQ----------PVFYYRRVRKMSNAELALLLFIILTV 164
Query: 209 EDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRT 268
+ +S + LDE K + ++ + + + +K E ++
Sbjct: 165 GHYAVVWSIYLE-------KQLDELLSRKKREKKKKTGSKSVDVSKLGASEKNERLLMKP 217
Query: 269 LVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE 328
+ C I + + + AK KE KEK E A E E
Sbjct: 218 QWHDLLPCKLGIWFCLTLKALPHLIQDAGQFYAKYKETRLKEK------EDALTRTELET 271
Query: 329 EEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+ +++ K E + Q + IEEI EQ+ + E R R K
Sbjct: 272 LQKQKKVKKPKPEFPVYTPLETTYIQSYDHGTSIEEIEEQM---DDWLENRNRTQKKQAP 328
Query: 389 KSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIG 448
+ W+E+DL L +++ FP GT RWE IA+ + R+ DV
Sbjct: 329 E-----------WTEEDLSQLTRSMVKFPGGTPGRWEKIAHELG--------RSVTDVTT 369
Query: 449 KAKSLQ 454
KAK L+
Sbjct: 370 KAKQLK 375
Score = 38.1 bits (87), Expect = 0.022
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 501 WTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMV 550
WT E+ L +++ +P TP RWEKIA + GR+ D + K+L + V
Sbjct: 330 WTEEDLSQLTRSMVKFPGGTPGRWEKIAHEL-GRSVTDVTTKAKQLKDSV 378
Score = 35.4 bits (80), Expect = 0.14
Identities = 36/165 (21%), Positives = 71/165 (43%), Gaps = 31/165 (18%)
Query: 297 AKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKL 356
A+ A +EQE +++ A A+ + + R AK E + +K R K
Sbjct: 417 AEGVAAEEEQEGDSGEQET---GATDARPRRRKPARLLEATAKPEPE------EKSRAKR 467
Query: 357 RNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLF 416
+ I E NE + E+ ++ +++ E+ W+++ +LL A+ +
Sbjct: 468 QKDFDIAEQNES-----SDEESLRKERARSAEEP----------WTQNQQKLLELALQQY 512
Query: 417 PAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQK 461
P G++ RW+ IA + ++ +D I + K L +L +K
Sbjct: 513 PRGSSDRWDKIARCV-------PSKSKEDCIARYKLLVELVQKKK 550
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 68.9 bits (167), Expect = 1e-11
Identities = 48/176 (27%), Positives = 91/176 (51%), Gaps = 8/176 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E EK K E R++ R E+ + + +RKKEE R + + +K K++EK ++
Sbjct: 65 EREKRKRE-REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
Query: 292 EAEKKAKAEAKRKEQEAKE--KQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI 349
K E +RKE+ +E K+R+ + E +E++E + R++ + +KE++ ++K
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
Query: 350 KKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDD 405
K+ +++ RN + E E+ RKE+ E R ++ K E+ + NW E +
Sbjct: 184 KERKKRERN--RKERKKERERKERRE---RKKERKKKEERKKERQKDRQTNWREKE 234
Score = 66.6 bits (161), Expect = 6e-11
Identities = 41/159 (25%), Positives = 86/159 (54%), Gaps = 7/159 (4%)
Query: 232 EEEKEKAECRDERRWIE-KQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
E +KE+ E + RR E K+ ++KKE+ R RT S + + ++ KEE K +
Sbjct: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT------SKEGKERERKEERKRE 142
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E++ K E + KE+E KE++++ + +E++E+E +++ + K+ +K+ +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
KER++ + K +E ++ R++ + R ++ K K
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
Score = 65.9 bits (159), Expect = 1e-10
Identities = 49/167 (29%), Positives = 89/167 (53%), Gaps = 9/167 (5%)
Query: 225 REFSYLDEEEKEK-AECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
RE E +KE+ +E + ERR EK+ R +RK+E + + + R +K
Sbjct: 43 REIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK---GERKKEERERKK 99
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+ EK KE E+K KRK++E KE+ R ++ R KE+ + E R++ K+E++
Sbjct: 100 RRREKENKEGEEK----EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 344 IQK-KAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ + +K+R++ + K EE E+ RKE+++ E ++ K E+
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/145 (29%), Positives = 85/145 (58%), Gaps = 3/145 (2%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E ++ E +++R+ EK+ R ++ KE + + + R K+ +E+E+ +K
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE-RKKEEREKERERK 161
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
E +K+ + + KE+E KEK+R+ + R KE+++E R++ KKE+ +K+ KK
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK-KKEERKK 220
Query: 352 ERQKLR-NSCKIEEINEQIRKEKEE 375
ERQK R + + +E ++ RKE+++
Sbjct: 221 ERQKDRQTNWREKERGKRERKERKK 245
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/159 (31%), Positives = 81/159 (50%), Gaps = 23/159 (14%)
Query: 237 KAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKK 296
++E R+ R IE TR + KKE + R K+ +E EK K+E EK+
Sbjct: 35 QSEIREREREIE-----TRKEGKKERESE-------------RKKERREREKRKREREKE 76
Query: 297 AKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK--KERQ 354
K E +KE++ + K+ + E + R +EKE +E ++ KKEK + + K KER+
Sbjct: 77 RKRERGKKEKKGERKKEERERKKRR--REKENKEGEEKEKRKKKEKKERGRTSKEGKERE 134
Query: 355 KLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGG 393
+ + K EE E+ RK++E + R R+ K E+ G
Sbjct: 135 R-KEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
+E +E KE+ + +R K+ + +R+KE + R + + ++ +
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+E K +K+ E+ K ++KE+E KE+ R+ + E + + K+E + +Q +KE+
Sbjct: 181 KERKERKKRERNRK--ERKKERERKER-RERKKERKKKEERKKERQKDRQTNWREKERG- 236
Query: 345 QKKAIKKERQK 355
K +KER+K
Sbjct: 237 --KRERKERKK 245
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 68.2 bits (165), Expect = 2e-11
Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 13/144 (9%)
Query: 245 RWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEA--- 301
R + ++ R R QR++EE R R + R K+ +EE+ A+ EAE +A+ EA
Sbjct: 601 RLLAEKRRQAREQREREEQER-RLQAE-------RDKRMREEQLAR-EAEARAEREAEAR 651
Query: 302 KRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCK 361
+R+EQEA+EK + + E RL K+KEE E R + ++ + +K ++E+++ +
Sbjct: 652 RREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKR 711
Query: 362 IEEINEQIRKEKEEAEARMRQASK 385
+EEI ++ RK E +E + +Q SK
Sbjct: 712 LEEIMKRTRK-SEVSETKQKQDSK 734
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/100 (31%), Positives = 64/100 (64%), Gaps = 8/100 (8%)
Query: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
EE + AEK+ +A R+++E +E++R+ L+A R + +EE+ R+ A++E + +
Sbjct: 597 EEATRLLAEKRRQA---REQREREEQERR--LQAERDKRMREEQLAREAEARAEREAEAR 651
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASK 385
++ ++ R+K + +E E+++K+KEEAEAR R+ ++
Sbjct: 652 RREEQEAREKAQAE---QEEQERLQKQKEEAEARSREEAE 688
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/113 (27%), Positives = 65/113 (57%), Gaps = 10/113 (8%)
Query: 286 EEKAKKEAEKKAKAEA--K-RKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
E++ ++E E++ +AE + R+EQ A+E + +AE EA A+ +EE+E R++A ++E+
Sbjct: 612 EQREREEQERRLQAERDKRMREEQLAREAEARAEREAE--ARRREEQEAREKAQAEQEEQ 669
Query: 343 DIQKKAIKKERQKLRNSCKIEEIN-----EQIRKEKEEAEARMRQASKNTEKS 390
+ +K ++ + R + + + +Q +E++E R+ + K T KS
Sbjct: 670 ERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKS 722
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 16/134 (11%)
Query: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD---------PRI 280
L E + +AE E R E+Q +AQ ++EE R++ + A + R
Sbjct: 636 LAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLERE 695
Query: 281 KKFKEEEKAKKEAEKKAKAEAKR--KEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLA 338
K F+++E+ ++E K+ + KR K + ++ KQ+Q EA A E V+ +
Sbjct: 696 KHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEAN--ANGSSPEPVK---AVE 750
Query: 339 KKEKDIQKKAIKKE 352
+ +QK+A++KE
Sbjct: 751 ARSPGLQKEAVQKE 764
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/127 (25%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE +E+E+ RD+R E+ R A+ ++E R R + ++ +
Sbjct: 611 REQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQE 670
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+K K+EAE +++ EA+R+ E ++ +Q E E R + K EE+ ++ ++ +
Sbjct: 671 RLQKQKEEAEARSREEAERQRLEREKHFQQQEQE--RQERRKRLEEIMKRTRKSEVSETK 728
Query: 345 QKKAIKK 351
QK+ K+
Sbjct: 729 QKQDSKE 735
Score = 37.0 bits (84), Expect = 0.049
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 298 KAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKL- 356
K E K+ + K + + E A LA +K +++ A +EK +Q++ + E Q+L
Sbjct: 129 KQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLK 188
Query: 357 ---RNSCKIEEINEQIRKEKEEAEARMRQASKNT 387
R + E +++ K KE EA ++++ K T
Sbjct: 189 AEQRRAALEERQRQKLEKNKERYEAAIQRSVKKT 222
Score = 35.4 bits (80), Expect = 0.14
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 6/96 (6%)
Query: 279 RIKKFKEEEKAKKEAEKKAK-AEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
++ K + EE+AK A KKA E + K + +EKQ Q RL +++ + E R+ AL
Sbjct: 140 KLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRR--RLEEQRLKAEQRRAAL- 196
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEK 373
+E+ QK KER + +++ +IR+++
Sbjct: 197 --EERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQR 230
Score = 34.7 bits (78), Expect = 0.24
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 19/102 (18%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
EE+ K + W+EK+ +A +A R+K+ R R L EE++ K E
Sbjct: 147 EERAKYLAAKKAVWLEKEEKA-KALREKQLQERRRRL---------------EEQRLKAE 190
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ 334
+ A E +R++ E +++ +A A + + +K E+RQQ
Sbjct: 191 QRRAALEERQRQKLEKNKERYEA---AIQRSVKKTWAEIRQQ 229
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/70 (24%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Query: 309 KEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQ-KLRNSCKIEEINE 367
+E+ + E R A+E+ E E +++ L A+++K ++++ + +E + + + E
Sbjct: 596 REEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREE 655
Query: 368 QIRKEKEEAE 377
Q +EK +AE
Sbjct: 656 QEAREKAQAE 665
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 67.8 bits (164), Expect = 3e-11
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 13/202 (6%)
Query: 195 KKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIE--KQNR 252
K+N P D SF + + ++ R ++ ++K E D+RR +E K R
Sbjct: 521 KRNTPLRMDPKCSFVEKER-----QRLENLRRKEEAEQLRRQKVE-EDKRRRLEEVKLKR 574
Query: 253 ATRAQRKKEEMNRIRTLVDNAYS-CDPRIKKFKEE-EKAKKE--AEKKAKAEAKRKEQEA 308
R ++ + R+ + + + + + E+ EKAK+E AE+KAK +A K+ E
Sbjct: 575 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 634
Query: 309 KEKQRQAELEAARLA-KEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINE 367
E +R+ E EA RL ++EEEE R Q LL KK+++ Q++ K K + +E E
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 694
Query: 368 QIRKEKEEAEARMRQASKNTEK 389
Q R+E+E E R+ + ++
Sbjct: 695 QERREQERREQERREQERREQE 716
Score = 66.2 bits (160), Expect = 7e-11
Identities = 45/162 (27%), Positives = 93/162 (57%), Gaps = 13/162 (8%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQ-----RKKEEMNRIRTLVDNAYSCDPR 279
++ ++ K++ E R RW++++ R Q +K+EE R+R + + R
Sbjct: 630 KKMEEVEARRKQEEEAR-RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 688
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK 339
++ +E+E+ ++E ++ + E +R+EQE + +++ E RL E+E +E R++AL +
Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE-REKALRLQ 747
Query: 340 KE---KDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEA 378
KE +++++K K+E+Q+L +++E EQ +K KE A A
Sbjct: 748 KEQLQRELEEKKKKEEQQRLAER-QLQE--EQEKKAKEAAGA 786
Score = 60.1 bits (144), Expect = 5e-09
Identities = 50/187 (26%), Positives = 92/187 (49%), Gaps = 24/187 (12%)
Query: 225 REFSYLDEEEKEKAECR-----DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279
+E +E+ K+KA + + RR E++ R R +++EE R + L+
Sbjct: 614 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK------- 666
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK 339
KK +E+E+ +K AE K AE + +E+ +E++ Q E R +E+ E+E RQ LA+
Sbjct: 667 -KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE-RQ---LAE 721
Query: 340 KEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEAR-------MRQASKNTEKSTG 392
+E+ +++ ++ ER+ + EQ+++E EE + + RQ + EK
Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Query: 393 GGGNGSK 399
SK
Sbjct: 782 EAAGASK 788
Score = 46.6 bits (109), Expect = 6e-05
Identities = 35/182 (19%), Positives = 86/182 (47%), Gaps = 25/182 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
+ +E+ E E + + + + + K E+ R + A K + E + K+E
Sbjct: 583 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE 642
Query: 293 AEKK-----AKAEAKRKEQEAKEKQRQAE-------LEAARLAKEKEE------------ 328
E + + E +R+ QE +K+++ E EA RLA+++E+
Sbjct: 643 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702
Query: 329 -EEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNT 387
E+ R++ ++E+ + ++ ++E+++L+ +++E + +R +KE+ + + + K
Sbjct: 703 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 762
Query: 388 EK 389
E+
Sbjct: 763 EQ 764
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/82 (29%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Query: 310 EKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQI 369
EK+RQ L +++E E++R+Q + K + +++ +K+E ++LR + E EQ+
Sbjct: 536 EKERQ---RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE-ERLRKVLQARERVEQM 591
Query: 370 RKE-KEEAEARMRQASKNTEKS 390
++E K++ E + Q + TEK+
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKA 613
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 67.8 bits (164), Expect = 3e-11
Identities = 58/189 (30%), Positives = 93/189 (49%), Gaps = 33/189 (17%)
Query: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKK------- 282
+D +EKE+ + RR + A + +R+K E ++ R L + + R++K
Sbjct: 528 MDPKEKERQRLENLRR----KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
Query: 283 ---FKEE----------------EKAKKE--AEKKAKAEAKRKEQEAKEKQRQAELEAAR 321
KEE EKAK+E AE+KAK +A K+ E E +R+ E EA R
Sbjct: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Query: 322 LA-KEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARM 380
L ++EEEE R Q LL KK+++ Q++ K K + +E EQ R+E+E E
Sbjct: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER 703
Query: 381 RQASKNTEK 389
R+ + ++
Sbjct: 704 REQERREQE 712
Score = 66.2 bits (160), Expect = 7e-11
Identities = 45/162 (27%), Positives = 93/162 (57%), Gaps = 13/162 (8%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQ-----RKKEEMNRIRTLVDNAYSCDPR 279
++ ++ K++ E R RW++++ R Q +K+EE R+R + + R
Sbjct: 626 KKMEEVEARRKQEEEAR-RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 684
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK 339
++ +E+E+ ++E ++ + E +R+EQE + +++ E RL E+E +E R++AL +
Sbjct: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE-REKALRLQ 743
Query: 340 KE---KDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEA 378
KE +++++K K+E+Q+L +++E EQ +K KE A A
Sbjct: 744 KEQLQRELEEKKKKEEQQRLAER-QLQE--EQEKKAKEAAGA 782
Score = 60.1 bits (144), Expect = 5e-09
Identities = 50/187 (26%), Positives = 92/187 (49%), Gaps = 24/187 (12%)
Query: 225 REFSYLDEEEKEKAECR-----DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279
+E +E+ K+KA + + RR E++ R R +++EE R + L+
Sbjct: 610 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK------- 662
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK 339
KK +E+E+ +K AE K AE + +E+ +E++ Q E R +E+ E+E RQ LA+
Sbjct: 663 -KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE-RQ---LAE 717
Query: 340 KEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEAR-------MRQASKNTEKSTG 392
+E+ +++ ++ ER+ + EQ+++E EE + + RQ + EK
Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Query: 393 GGGNGSK 399
SK
Sbjct: 778 EAAGASK 784
Score = 46.6 bits (109), Expect = 6e-05
Identities = 35/182 (19%), Positives = 86/182 (47%), Gaps = 25/182 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
+ +E+ E E + + + + + K E+ R + A K + E + K+E
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE 638
Query: 293 AEKK-----AKAEAKRKEQEAKEKQRQAE-------LEAARLAKEKEE------------ 328
E + + E +R+ QE +K+++ E EA RLA+++E+
Sbjct: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
Query: 329 -EEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNT 387
E+ R++ ++E+ + ++ ++E+++L+ +++E + +R +KE+ + + + K
Sbjct: 699 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
Query: 388 EK 389
E+
Sbjct: 759 EQ 760
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/85 (29%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Query: 307 EAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEIN 366
+ KEK+RQ L +++E E++R+Q + K + +++ +K+E ++LR + E
Sbjct: 529 DPKEKERQ---RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE-ERLRKVLQARERV 584
Query: 367 EQIRKE-KEEAEARMRQASKNTEKS 390
EQ+++E K++ E + Q + TEK+
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKA 609
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 66.6 bits (161), Expect = 6e-11
Identities = 42/166 (25%), Positives = 93/166 (56%), Gaps = 22/166 (13%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE--EEKA 289
EE +E+ R+E + +E++ R R +R++EE D +K+ +E +++
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERR------------DQLLKREEERRQQRL 590
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI 349
K+E E++ + KR+E E E++ + E RL +E+ EEE RQQ L ++++++ +++ +
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERRE---QRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 350 KKER-----QKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKS 390
++E+ Q+L+ + E + +++++E EE A + E++
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Score = 65.1 bits (157), Expect = 2e-10
Identities = 45/164 (27%), Positives = 88/164 (53%), Gaps = 22/164 (13%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+EE +E+ E R+++ E++ R + +++EE R++ ++ + E++ +
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQ-------------QRLRSEQQLR 539
Query: 291 KEAEKK-----AKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
+E E++ + E KR EQE +E++ + E E R K EEE RQQ L ++E+ ++
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ ++E ++L EE EQ K +E E R +Q K+ E+
Sbjct: 600 QRLKREEVERLEQ----EERREQRLKREEPEEERRQQLLKSEEQ 639
Score = 62.8 bits (151), Expect = 8e-10
Identities = 42/186 (22%), Positives = 89/186 (47%), Gaps = 14/186 (7%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECR--------DERRWIEKQNRATRAQRKKEEMNRIRTL 269
W W+E EE++ C+ DE + ++ R + ++E+ + R
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 270 VDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEE 329
D + + + K E +KE EK + E +R+ + +E+++ +LE L +E++EE
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 330 EV------RQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQA 383
E R+Q L K+E++ +++ ++ Q+ R + E +Q+R+E+EE + +
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 384 SKNTEK 389
+ E+
Sbjct: 354 EQEEER 359
Score = 62.8 bits (151), Expect = 8e-10
Identities = 41/153 (26%), Positives = 87/153 (56%), Gaps = 12/153 (7%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+EE++ + E R++R E++ R + +++EE + R + + R+K+ EE +
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR---EEVER 609
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
E E++ + KR+E E + +Q +L K +E+EE RQQ L +++++ +++ +K
Sbjct: 610 LEQEERREQRLKREEPEEERRQ--------QLLKSEEQEERRQQQ-LRREQQERREQRLK 660
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQA 383
+E ++ R +++ +E+ R+E+E AE QA
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 23/185 (12%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
+RE L +E +E+ R ER +++ R Q +++E R + +KF
Sbjct: 1669 FREEEQLLQEGEEQQLRRQER---DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+EEE+ ++E E++ +R + +E+Q + E E +L +++ + + R++ L ++ ++
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSE 403
Q ++ + +R K R EQ+R+E+EE + R +Q +G W E
Sbjct: 1786 QQLRSQESDR-KFRE-------EEQLRQEREEQQLRPQQR------------DGKYRWEE 1825
Query: 404 DDLQL 408
+ LQL
Sbjct: 1826 EQLQL 1830
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/167 (22%), Positives = 91/167 (54%), Gaps = 17/167 (10%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE ++E+E+ E ++ERR E+Q R + + ++E+ R R ++ +
Sbjct: 302 REQQLRRKQEEERREQQEERR--EQQERREQQEERREQQLR-------------REQEER 346
Query: 285 EEEKAKKEAEKKAKAEAKRKEQE--AKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
E++ ++E E++ + + R+EQE +E+Q + E + R + + E+++R++ L ++++
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+++ +++E+Q R E E+ ++K E E R ++ + E+
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/167 (26%), Positives = 90/167 (53%), Gaps = 11/167 (6%)
Query: 225 REFSYLDEEE--KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKK 282
RE Y +EEE +E+ + E R ++ R RK+EE+ + + +P ++
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE---EQLLREEPEKRR 1102
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
+E E+ +E E++ + E ++ +E +EK+R+ ELE + +EEEEV+Q+ +E+
Sbjct: 1103 RQERERQCRE-EEELQQEEEQLLREEREKRRRQELER----QYREEEEVQQEEEQLLREE 1157
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+++ + ERQ R ++++ EQ+ +E++E + R+ E+
Sbjct: 1158 PEKRRRQELERQ-YREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/168 (24%), Positives = 91/168 (54%), Gaps = 17/168 (10%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
R L E++E+ E + RR E++ R + +R++EE R + L R ++ +
Sbjct: 334 RREQQLRREQEERRE-QQLRREQEEERREQQLRREQEEERREQQL--------RREQQLR 384
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAAR---LAKEKEEEEVRQQALLAKKE 341
E++ ++E + + + + +R++Q +E+Q + E + R L +E+EEE Q K E
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ-----KHE 439
Query: 342 KDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ +++ +K+E+++ R+ K EE E+ +E+ + + + Q + E+
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/168 (25%), Positives = 90/168 (53%), Gaps = 25/168 (14%)
Query: 232 EEEKEKAE--------CRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSC-DPRIKK 282
EE+ EK E RDE W ++Q R +R+ EE + SC ++
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE--------EQLQSCKGHETEE 203
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVR-QQALLAKKE 341
F +EE+ + ++ E +RK +E K++QR+ + R+ +E+EE+E R ++ +L K+E
Sbjct: 204 FPDEEQLR----RRELLELRRKGREEKQQQRRERQD--RVFQEEEEKEWRKRETVLRKEE 257
Query: 342 KDIQKKAIKKERQKLRNSCKIEEINEQ-IRKEKEEAEARMRQASKNTE 388
+ +Q++ +++R+ ++ ++ Q +R+E++E E + ++ + +
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/169 (27%), Positives = 93/169 (55%), Gaps = 13/169 (7%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNR---IRTLVDNAYSCDP-RI 280
R L+ K + E + +RR E+Q+R + + +KE R +R + +P R
Sbjct: 211 RRRELLELRRKGREEKQQQRR--ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKK 340
++ +EEE+ ++ E++ E +R+ QE E+Q+Q L + + K+EEE R+Q ++
Sbjct: 269 RELQEEEEQLRKLERQ---ELRRERQE--EEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 341 EKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+++ +++ ++ Q+LR + E +Q+R+E+EE E R +Q + E+
Sbjct: 324 QQERREQQEERREQQLRRE-QEERREQQLRREQEE-ERREQQLRREQEE 370
Score = 55.5 bits (132), Expect = 1e-07
Identities = 39/161 (24%), Positives = 79/161 (49%), Gaps = 4/161 (2%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
EE +++ R+E R +Q R R Q ++ E R V+ + R ++ K EE ++
Sbjct: 572 EERRDQLLKREEER---RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
++ K+E + + ++ + ++ Q E RL +E+EEE + Q+ +E+ +++ ++
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Query: 352 ERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTG 392
E+++ R K Q + E EA+AR + K G
Sbjct: 689 EQEQARERIKSRIPKWQWQLE-SEADARQSKVYSRPRKQEG 728
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/187 (22%), Positives = 97/187 (51%), Gaps = 33/187 (17%)
Query: 225 REFSYLDEEE----KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRI 280
+E L EEE +E E ++ R +E+Q Q ++++ R+R + ++
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR--------EQQL 306
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAAR---LAKEKEEE-------- 329
++ +EEE+ +++ E++ + E + +++E +E+Q + E E R L +E+EEE
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 330 ----EVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQ 382
E R+Q L ++E+ ++++ + Q+LR ++ +Q+R+E++ E + R Q
Sbjct: 367 EQEEERREQQL--RREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQ 423
Query: 383 ASKNTEK 389
+ ++
Sbjct: 424 QLRREQE 430
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/165 (23%), Positives = 92/165 (55%), Gaps = 13/165 (7%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+E +++ + ++E ++++ R+ + R+++E R + L + R+++ + E++ K
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE---EKRLEQERREQRLK 568
Query: 291 KEAEKKAKAEAKRKEQEAKE--KQRQAELEAARLAKEK----EEEEVRQQALLAKK-EKD 343
+E E++ KR+E+ ++ K+ Q E RL +E+ E+EE R+Q L ++ E++
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKE---KEEAEARMRQASK 385
+++ +K E Q+ R ++ ++ R++ +EE E R+ Q K
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/167 (26%), Positives = 83/167 (49%), Gaps = 27/167 (16%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRAT--RAQRKKEEMNRIRTLVDNAYSCDPRIKK 282
RE Y +EEE ++ E + R EK+ R R RKK+E+ +
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ----------------- 1028
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQ-----AELEAARLAKEKEEEEVRQQALL 337
+EE+ ++E EK+ E +R+ +E +E Q++ E R +E E + +++ L
Sbjct: 1029 -EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKE--KEEAEARMRQ 382
++E+ ++++ K+ RQ+ C+ EE +Q ++ +EE E R RQ
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Score = 54.3 bits (129), Expect = 3e-07
Identities = 35/144 (24%), Positives = 85/144 (59%), Gaps = 13/144 (9%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
+E+E+ +CR+E +++ + R +R+K R R ++ Y + +++ +EE+ ++E
Sbjct: 1104 QERER-QCREEEELQQEEEQLLREEREK----RRRQELERQYREEEEVQQ-EEEQLLREE 1157
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKE 352
EK+ + E +R+ +E +E Q++ E +L +E++E+ +++ ++E+++Q+ +K
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEE----QLLREEQEKRRQERERQYREEEELQR---QKR 1210
Query: 353 RQKLRNSCKIEEINEQIRKEKEEA 376
+Q+ R+ + ++ Q EKE A
Sbjct: 1211 KQRYRDEDQRSDLKWQWEPEKENA 1234
Score = 53.5 bits (127), Expect = 5e-07
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 34/183 (18%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQR----------KKEEMNRIRTLVDNAY 274
+E L EEE+E E+R ++Q R R + ++E R R + Y
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 275 SCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ 334
D ++++ KEE+ +E EK+ + E ++K +E +E Q++ E +L +E+ E+ RQ+
Sbjct: 961 RKDKKLQQ-KEEQLLGEEPEKRRRQEREKKYREEEELQQEEE----QLLREEREKRRRQE 1015
Query: 335 ALLAKKEKDI----QKKAIKKERQKLRNSCKIEEINEQIRKEK-----------EEAEAR 379
++KD +++ +++ER+K R ++E Q R+E+ EE E R
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRR----LQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 380 MRQ 382
RQ
Sbjct: 1072 RRQ 1074
Score = 53.1 bits (126), Expect = 7e-07
Identities = 38/165 (23%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
R L E++ + E ++E R +K + R QR K E R + + ++ +
Sbjct: 414 RREQQLRREQQLRRE-QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+++ + + E++ + K +E+E +E+Q + E + R E+EE R+Q L ++E++
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR-----EQEERREQRLKRQEEEER 527
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ ++ E+Q R EE EQ+ K +EE + + ++
Sbjct: 528 LQQRLRSEQQLRREQ---EERREQLLKREEEKRLEQERREQRLKR 569
Score = 53.1 bits (126), Expect = 7e-07
Identities = 45/168 (26%), Positives = 92/168 (54%), Gaps = 23/168 (13%)
Query: 224 WREFSYLDEEEKEKAECRDER--RWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIK 281
+RE L +E +E+ R ER +++E++ + R +R+++ + R +
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH-------------DRDR 1667
Query: 282 KFKEEEKAKKEAEKKA--KAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK 339
KF+EEE+ +E E++ + E RK +E +++ R+ E E L +EE+++R+Q L K
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL---QEEQQLRRQELERK 1724
Query: 340 KEKDIQKKAIKKERQKLRNSCKIEEI--NEQIRKEKEEAEARMRQASK 385
++ Q + + E+++LR + +I EQ+R E+EE + R ++ +
Sbjct: 1725 FREEEQLRQ-ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Score = 52.8 bits (125), Expect = 9e-07
Identities = 40/172 (23%), Positives = 88/172 (51%), Gaps = 27/172 (15%)
Query: 231 DEEEKEKAECRD-------ERRWIEKQNRATRAQRK--KEEMNRIRTLVDNAYSCDPRIK 281
+E+++++ E +D E+ W +++ + + K +EE R R L + + +++
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE----EEQLR 279
Query: 282 KFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE-----EEVRQQAL 336
K + +E ++ E++ + + R+EQ+ + KQ + E +E++E EE R+Q L
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 337 LAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
++E ++ Q+LR + E +Q+R+E+EE E R +Q + +
Sbjct: 340 RREQE--------ERREQQLRREQEEERREQQLRREQEE-ERREQQLRREQQ 382
Score = 52.8 bits (125), Expect = 9e-07
Identities = 38/168 (22%), Positives = 97/168 (57%), Gaps = 19/168 (11%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E++E+ E ++ERR E+Q R + +R+++++ R + + ++++ +EEE ++E
Sbjct: 323 EQQERREQQEERR--EQQLRREQEERREQQLRREQ----EEERREQQLRREQEEE--RRE 374
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEV-------RQQALLAKKEKDIQ 345
+ + + + +R++Q +E+Q + E + R + + E+++ R+Q L ++E++
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKE----EAEARMRQASKNTEK 389
++ ++ER++ R + EE + +++E+E E E R +Q ++ E+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 27/190 (14%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQ----------NRATRAQRKKEEMNRIRTLVDNAY 274
RE +L EEE EK + R +RR EK+ R RAQ+ +EE + ++ +
Sbjct: 806 REQRFLPEEE-EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 275 SCDPRIKK-----FKEEEKAKKEA--EKKAKAEAKRKEQ-----EAKEKQRQAELEAARL 322
S + R + +EE K ++ K A E RKEQ E +E QR+ + R
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 323 AKEK---EEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEAR 379
+E+ EEE+++Q+ +E+ +++ ++ERQ R K+++ EQ+ E+ E R
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQ-YRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 380 MRQASKNTEK 389
+ K E+
Sbjct: 984 QEREKKYREE 993
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/177 (24%), Positives = 89/177 (50%), Gaps = 18/177 (10%)
Query: 230 LDEEEKEKAECRDERRWIE-KQNRATRAQRKKEEMNRIRTL-----VDNAYSCDPRIKKF 283
L EEE E ++ RR E ++++ R Q ++E R TL + + ++ +
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL----EAARLAKEKEEEEVRQQALLAK 339
+EEE ++E EK+ + E +R+ +E ++ Q++ E E + +++ E + R+ L +
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 340 KEKDI-----QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARM---RQASKNTE 388
KE+ + +K+ ++ +K R ++++ EQ+ +E+ E R RQ K E
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/160 (20%), Positives = 80/160 (50%), Gaps = 3/160 (1%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQR--KKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
EEE E+ E ++ +++ R +R K EE R R + R ++ + E++
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEER-REQQERREQQLRREQEERREQRL 519
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI 349
K++ E++ + R EQ+ + +Q + + + +EK E+ R++ L +++++ + + +
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 350 KKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
K+E ++ + K E+ ++ K E R+ Q + ++
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/152 (25%), Positives = 81/152 (53%), Gaps = 14/152 (9%)
Query: 234 EKEKAECRDERRWIEKQNRATRAQRKKE---EMNRIRTLVDNAYSCDPRIKKFKEEEK-- 288
E+E R+++E++ R R +R+++ E ++R R +KF+EEE+
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL 1423
Query: 289 AKKEAEKKAKAE---AKRKEQEAKEKQRQAELEAARLAKEKEEEEV---RQQALLAKKEK 342
+++E ++K + E +R+E+E K + + +L R K +EEE++ R++ L ++E+
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1483
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
D + +E Q+LR + + EQ + +E
Sbjct: 1484 D---RKFLEEEQQLRRQERDRKFREQELRSQE 1512
Score = 50.1 bits (118), Expect = 6e-06
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 18/181 (9%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSC--DPRIKK 282
RE +L+EE++ + E R + E+Q R +++ R R ++ R +K
Sbjct: 1444 RERKFLEEEQQLRQE-RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 283 FKEEEKAKKEAEKKAKAEAKR------------KEQEAKEKQRQAELEAARLAKEKEEEE 330
F+E+E +E E+K E ++ +EQ+ + ++R + R K +EEE+
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 331 VRQQA---LLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNT 387
+RQ+ L+++E+D + + +++ ++ K E +Q+R+++ + + R + K
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
Query: 388 E 388
E
Sbjct: 1623 E 1623
Score = 50.1 bits (118), Expect = 6e-06
Identities = 46/194 (23%), Positives = 96/194 (49%), Gaps = 43/194 (22%)
Query: 225 REFSYLDEEEKEKAECRD-------------ERRWIEKQNRATRAQRKK---EEMNRIRT 268
R+ +L+EE++ + + RD ER+++E++ + R QR++ +E ++R
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 269 LVDNAYSCDPRIKKFKEEEKAKKEAE------------------KKAKAEAKRK----EQ 306
R +KF+EEE+ ++E E K + E +RK EQ
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 307 EAKEKQRQAELEAARLAKEKEEEEV---RQQALLAKKEKDIQKKAIKKERQKLRNSCKIE 363
+ + ++ Q +L R K +E+E++ R++ L ++E+D +K +++E Q R + +
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD--RKFLEEEPQLRRQEREQQ 1660
Query: 364 EINEQIRKEKEEAE 377
+++ RK +EE +
Sbjct: 1661 LRHDRDRKFREEEQ 1674
Score = 49.3 bits (116), Expect = 9e-06
Identities = 47/205 (22%), Positives = 92/205 (44%), Gaps = 27/205 (13%)
Query: 226 EFSYLDEEEKEKAECRDERRWIEKQ---------NRATRAQRK-KEEMNRIRTLVDNAYS 275
E L+ EE+++A+ RD + EKQ R RK +EE ++ +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 276 CDPRIKKFKEEEKAKKEAEKKAKAEAKR------------KEQEAKEKQRQAELEAARLA 323
R +KF+EEE +E +K E +R +EQ+ + ++R+ +L R
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 324 KEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQA 383
K +EEE+ + +K ++ +++ ++ER++ K E +Q+R+E+ Q
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERER-----KFLEEEQQLRQERHRKFREEEQL 1469
Query: 384 SKNTEKSTGGGGNGSKNWSEDDLQL 408
+ E+ + + E++ QL
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQQL 1494
Score = 49.3 bits (116), Expect = 9e-06
Identities = 38/160 (23%), Positives = 88/160 (55%), Gaps = 11/160 (6%)
Query: 229 YLDEEEKEKAECRDERRWIEKQNRAT---RAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
+L+EE++ + + R ER++++++ + R Q+ +++ +R + S R +KF+E
Sbjct: 1376 FLEEEQRLRRQER-ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434
Query: 286 EEKA--KKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK-KEK 342
EE+ ++E E+K E ++ QE K R+ E +L +E+EE+++ +Q K E+
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEE----QLLQEREEQQLHRQERDRKFLEE 1490
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
+ Q + +++R+ + +E + +E+++ + RQ
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
Score = 49.3 bits (116), Expect = 9e-06
Identities = 45/173 (26%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 224 WREFSYLDEEEKEKAECRDER----RWIEKQNRATRAQRK-KEEMNRIRTLVDNAYSCDP 278
+RE L +E +E+ R ER R E++ R +RK E+ ++R
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 279 RIKKFKEEEKAKKEAEKKA--KAEAKRK----EQEAKEKQRQAELEAARLAKEKEEEEVR 332
R +KF+E+E+ +E E++ + E RK E + + ++R+ +L R K +EEE++
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 333 QQA---LLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
Q+ L ++E+D +K ++E+Q R + + + E+ + ++E E + R+
Sbjct: 1677 QEGEEQQLRRQERD--RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Score = 49.3 bits (116), Expect = 9e-06
Identities = 45/165 (27%), Positives = 83/165 (50%), Gaps = 8/165 (4%)
Query: 236 EKAECRDERRWIEKQNRATRAQRKKEEMNRIRT-LVDNAYSCDPRIKKFKEEEKAKKEAE 294
E+ + R ER E+Q R RK E ++R + +KF+EEE+ ++E E
Sbjct: 1751 EEEQLRPERE--EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 295 KKAKAEAKRK-EQEAKEKQRQAELEAARLAKEKEEE-EVRQQALLAKKEKDIQKKAIKKE 352
++ +R + +E+Q Q E + RL +E++ + +Q +K + +++ ++E
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 353 RQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNG 397
QK R + + E IR++++E E R RQ + KS G G+G
Sbjct: 1869 EQKRRQERERKLREEHIRRQQKE-EQRHRQVGE--IKSQEGKGHG 1910
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/175 (24%), Positives = 88/175 (50%), Gaps = 16/175 (9%)
Query: 224 WREFSYLDEEEKEKA-ECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKK 282
+RE L +EE++ E R++RR E++ + + ++ +++ ++ R KK
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 283 FKEEEKA--------KKEAEKKAKAE-----AKRKEQEAKEKQRQAELEAARLAKEKEEE 329
++EEE+ ++E EK+ + E K+ E + +E+Q E R +E+E +
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Query: 330 EVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKE--KEEAEARMRQ 382
++ L ++E+ + ++ + RQ+L + EE +Q ++ +EE E R RQ
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/160 (19%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
+RE L +E +++ R ER + R +R+++++ R D + + ++++
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER--DRKFREEEQLRQE 1782
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+EE++ + + + E ++ QE +E+Q + + + E+E+ ++ +Q ++E+D
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 344 IQKKAIKKERQKLRNSCKIEEI-NEQIRKEKEEAEARMRQ 382
Q +A ++ + ++ + +E+ E+ +K ++E E ++R+
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/163 (22%), Positives = 86/163 (52%), Gaps = 22/163 (13%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+EE +E+ R+++ E+Q R + R+++++ R + L R ++ + E++ +
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--------RREQQLRREQQLR 420
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+E + + + E +R EQ+ ++++R+ L K E+E R+ L K+E++ ++ +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRL--------KREQEERRDWL--KREEETERHEQE 470
Query: 351 KERQKLRNSCKIEEINEQIRKEKEE----AEARMRQASKNTEK 389
+ +Q+L+ + E ++ E+EE E R +Q + E+
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/163 (20%), Positives = 80/163 (49%), Gaps = 11/163 (6%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
EEE++ + +R++ E++ + R +R+++ + + L R +KF+EEE+ +
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE------RHRKFREEEQLLQ 1471
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI-----QK 346
E E++ +R + +E+Q+ E R +E+E + ++E+ + Q+
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 347 KAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
K +++E+Q R + ++ RK +EE + R + + +
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Score = 47.4 bits (111), Expect = 4e-05
Identities = 46/197 (23%), Positives = 92/197 (46%), Gaps = 41/197 (20%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
R L EE+E+ + RR E+Q R + +++EE R+ + + + R ++
Sbjct: 629 RRQQLLKSEEQEERRQQQLRR--EQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 285 EEE-----------------KAKKEAE----------KKAKAEAKRKEQEAKEKQRQAEL 317
EEE + + EA+ +K + + +R+EQE K ++R++EL
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 318 ---EAARLAKEKEEEEVR-----QQALLAKKEKDIQKKA----IKKERQKLRNSCKIEEI 365
E R ++++EEE R Q K E+ Q+ + ++++R++ + + ++
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Query: 366 NEQIRKEKEEAEARMRQ 382
++ E+EE E R RQ
Sbjct: 807 EQRFLPEEEEKEQRRRQ 823
Score = 47.0 bits (110), Expect = 5e-05
Identities = 39/152 (25%), Positives = 81/152 (53%), Gaps = 11/152 (7%)
Query: 226 EFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
E Y EEE ++ E + R EK+ R R ++ +EE + + + R K+ ++
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE--EEQLLREEREKRRRQ 1134
Query: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
E + + E++ + E ++ +E EK+R+ ELE + +EEEE++Q+ +E+ ++
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELER----QYREEEELQQE-----EEQLLR 1185
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAE 377
++ K+ +++ R + EE+ Q RK++ E
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Score = 46.6 bits (109), Expect = 6e-05
Identities = 39/173 (22%), Positives = 93/173 (53%), Gaps = 20/173 (11%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
R+ + EE+K + + ER+++E + + R++E ++R D + D ++ + +
Sbjct: 1577 RDRKFRLEEQKVRRQ-EQERKFMEDEQQL----RRQEGQQQLRQERDRKFREDEQLLQER 1631
Query: 285 EE------EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLA 338
EE E+ +K E++ + + +EQ+ + + + E +L +E EE+++R+Q
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR 1691
Query: 339 K-KEKDIQKKAIKKERQKLRNSCKI--EEI------NEQIRKEKEEAEARMRQ 382
K +E++ Q + ++ER+ L+ ++ +E+ EQ+R+E E+ + R ++
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/171 (20%), Positives = 84/171 (49%), Gaps = 15/171 (8%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR----I 280
RE Y +EEE ++ + R +R E Q + Q + E+ N +R DN C R
Sbjct: 1195 RERQYREEEELQRQK-RKQRYRDEDQRSDLKWQWEPEKENAVR---DNKVYCKGRENEQF 1250
Query: 281 KKFKEEEKAKKEAEKKAK------AEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ 334
++ ++ + +++++ + E R+++ + +QR + +E++E +++
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 335 ALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASK 385
+++EK + ++ +++R++ K E EQ+ +E+EE R ++ +
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFRE-EEQLLQEREEQPLRRQERDR 1360
Score = 44.7 bits (104), Expect = 2e-04
Identities = 40/156 (25%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLV-DNAYSCDPRIKKFKEEEKAKK 291
E++E+ E R +R E++ R + +++E R + L + + R+K+ EEE+ +
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR--EEEEERL 668
Query: 292 EAEKKAKAEAKRKEQE-AKEKQRQA-ELEAARLAK----EKEEEEVRQQALLAK-KEKDI 344
E K + E +R+EQE A+E+Q QA E +R+ K + E + RQ + ++ ++++
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 345 QKKAIKKERQKLRNSCKIE-EINEQIRKEKEEAEAR 379
Q++ ++E ++ R +++ + E+ ++++E E R
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/165 (18%), Positives = 77/165 (46%), Gaps = 10/165 (6%)
Query: 235 KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAE 294
+ +A+ R + + + + + +R+++E R R + + + R + ++EE+ +++
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768
Query: 295 KKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQ 354
+ +AE K + + R E EE + R+Q L ++E+ Q++ ++ER+
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 355 K----------LRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
K L+ + +++ E+ +E+ E R Q + +K
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 29/196 (14%)
Query: 230 LDEEEKEKAECRD----ERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
LDEE++ + + ++ +RR E Q R R+ EE R R ++ +E
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR-------QKRQEQERE 147
Query: 286 EEKAKKEAEKKAKAEAK----------RKEQEAKEK-QRQAELEAARLAKEKEEEEVRQQ 334
+ ++++EK+ + E + R+ QE +E+ +R+AE E + K E EE +
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 335 ALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQA--SKNTEKSTG 392
L ++E ++ ++E+Q+ R E +++ +E+EE E R R+ K EK
Sbjct: 208 EQLRRRELLELRRKGREEKQQQR-----RERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 393 GGGNGSKNWSEDDLQL 408
+ E++ QL
Sbjct: 263 EEPQRQRELQEEEEQL 278
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/197 (20%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
Query: 224 WREFSYLDEEEKEKAECRDER-RWI--EKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRI 280
W+E +++E+ + RD +W EK R + + + R A R
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKK 340
++F EE+ K++ ++ + K + +E+Q Q A +L +E++ + Q+ +++
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 341 EKDIQK--KAIKKERQKLRNSCKIE-EINEQIRKE-----KEEAEARMRQASKNTEKSTG 392
++ QK +++ER++ R++ + + EQ+RKE +EE E + + K +
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 393 GGGNGSKNWSEDDLQLL 409
+ +++ QLL
Sbjct: 928 RQYREEEQLQQEEEQLL 944
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 14/111 (12%)
Query: 232 EEEKEKAECRDER-RWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
EE++ + + RD + RW E+Q + +E+ R+R D Y + ++F +EK++
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQ------LQLEEQEQRLRQERDRQYRAE---EQFATQEKSR 1858
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKE 341
+E ++ + E +++ QE + K R+ + ++KEE+ RQ + +E
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIR----RQQKEEQRHRQVGEIKSQE 1905
Score = 38.9 bits (89), Expect = 0.013
Identities = 41/201 (20%), Positives = 92/201 (45%), Gaps = 32/201 (15%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMN-RIRTLVDN-----AYSCDP 278
RE EEE+E+ E R +R E++ A+ ++E+ RI++ + D
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 279 RIKKF--------------KEEEK-AKKEAEKKAKAEAKRKEQEAKEKQR---------- 313
R K ++EEK ++E+E + + E + Q+ +E+QR
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 314 -QAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKE 372
++E RL+ E R++ L A++ + +++ + +E +K + + E ++++
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 373 KEEAEARMRQASKNTEKSTGG 393
+EE + + R+ ++ ++ G
Sbjct: 835 EEEEQLQRRERAQQLQEEEDG 855
Score = 37.7 bits (86), Expect = 0.028
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 48/203 (23%)
Query: 232 EEEKEKAECRDERRW--IEKQNRATRAQRKKEEM-------NRIRTLVDNAYSCDPRIKK 282
EEE+ E R++RR +E+Q R +++EE R R ++ Y + +++
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAAR--------------------- 321
EEE+ +E ++K + E +R+ +E +E QRQ + R
Sbjct: 1179 --EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 322 ----LAKEKEEEEVRQ----QALLAKKEKDIQ-------KKAIKKERQKLRNSCKIEEIN 366
K +E E+ RQ Q + ++D+Q ++ ++ER++ + +
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 367 EQIRKEKEEAEARMRQASKNTEK 389
EQ+ +E E+ EA+ R EK
Sbjct: 1297 EQLERE-EQKEAKRRDRKSQEEK 1318
Score = 34.3 bits (77), Expect = 0.31
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
R+ Y EEE+ + E E+R ++++R RA+ + + R + +
Sbjct: 1817 RDGKYRWEEEQLQLE-EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ--------E 1867
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQ 314
EE+K ++E E+K + E R++Q+ +++ RQ
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 66.2 bits (160), Expect = 7e-11
Identities = 43/154 (27%), Positives = 89/154 (57%), Gaps = 13/154 (8%)
Query: 247 IEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEE-----EKAKKEAEKKAKAEA 301
+ ++ R R Q+++EE R+ + + +K +EE E+A+K+ E++ + E
Sbjct: 404 LAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEE 463
Query: 302 KRKEQEAKEKQRQAE-----LEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKL 356
++K+QE +EK++ E E L KEK+E+E +++A++ K+++ + KA ++ +++
Sbjct: 464 EKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKA-REVAEQM 522
Query: 357 RNSCKIEEINEQIRKEKEEAEARMRQASKNTEKS 390
R + E+I QI +E+ E + R+ + K T KS
Sbjct: 523 R--LEREQIMLQIEQERLERKKRIDEIMKRTRKS 554
Score = 63.9 bits (154), Expect = 4e-10
Identities = 43/147 (29%), Positives = 79/147 (53%), Gaps = 21/147 (14%)
Query: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
+++EE+++ E + +R E++ + +K+E R K +EEEK
Sbjct: 423 VEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER----------------KRQEEEKK 466
Query: 290 KKEAEKKAKA--EAKRKEQE---AKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
K+E E+K KA EAKRK +E KEKQ Q + E A + K+KE E + + + + +
Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRK 371
++ ++ E+++L +I+EI ++ RK
Sbjct: 527 EQIMLQIEQERLERKKRIDEIMKRTRK 553
Score = 50.8 bits (120), Expect = 3e-06
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
E K E ++A+ + +++EQE EK+ Q LE L ++ EEE +R + K+E++
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKS 390
+++ +K++Q+ K E E RK +EE + +Q + EK+
Sbjct: 459 KRQEEEKKKQEGEEKRKAGE--EAKRKAEEELLLKEKQEQEKQEKA 502
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/140 (29%), Positives = 73/140 (52%), Gaps = 20/140 (14%)
Query: 252 RATRAQRKKEEMNRIRTLVDN--AYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAK 309
R T K E +RT N + +K + + AK+ E++ K A R EQ+
Sbjct: 19 RGTSLPGKIAEPGAVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAR-EQQIL 77
Query: 310 EKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQI 369
EKQ++ ARL EK+ EE R + L +++++ QK+A +E++K +++
Sbjct: 78 EKQKR-----ARLQYEKQMEE-RWRKLEEQRQREDQKRAAVEEKRK-----------QKL 120
Query: 370 RKEKEEAEARMRQASKNTEK 389
R+E+E EA MR++ + T++
Sbjct: 121 REEEERLEAMMRRSLERTQQ 140
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 255 RAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKK--AKAEAKRKEQEAKEKQ 312
+A+++K R TL A P+ ++ E+ K A +K A A K + A K
Sbjct: 333 KAEKEKSNKEREGTLAQQA--AGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKP 390
Query: 313 RQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKE-----RQKLRNSCKIE--EI 365
+A AK E+ R+QA L +KE++ Q++ K+E R++L+ + E +
Sbjct: 391 TAGTTDAGEAAKILAEK--RRQARL-QKEQEEQERVEKEEQDRLEREELKRKAEEERLRL 447
Query: 366 NEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQL 408
E+ RK++EE + + + K + G +K +E++L L
Sbjct: 448 EEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL 490
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/70 (30%), Positives = 44/70 (62%), Gaps = 2/70 (2%)
Query: 284 KEEEKAKKEAEKKAKAE-AKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
+++++A+ + EK+ + K +EQ +E Q++A +E R K +EEEE R +A++ + +
Sbjct: 78 EKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEE-RLEAMMRRSLE 136
Query: 343 DIQKKAIKKE 352
Q+ +KK+
Sbjct: 137 RTQQLELKKK 146
Score = 34.7 bits (78), Expect = 0.24
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 24/108 (22%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
EE+EK E++ +EKQ RA R Q +K+ EE+ +K
Sbjct: 63 EEREKCLAAREQQILEKQKRA-RLQYEKQM-----------------------EERWRKL 98
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKK 340
E++ + + KR E K KQ+ E E A + E QQ L KK
Sbjct: 99 EEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKK 146
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/192 (23%), Positives = 95/192 (49%), Gaps = 16/192 (8%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
W + R + E++EK ++E W EK+ + + K E +IR
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKIRELEEKMHEQEKIRE--------- 455
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
+ +K +EEEK + E EK+ + EAK QE K ++++ ++ ++EE++ +Q +
Sbjct: 456 -QEEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKI----EEINEQIRKEKEEAEARMRQASKNTEKSTGG 393
++EK +++ + ++ +K+R +I E+I+EQ K +++ E RQ K ++
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 394 GGNGSKNWSEDD 405
K W +++
Sbjct: 574 REQEEKVWRQEE 585
Score = 60.8 bits (146), Expect = 3e-09
Identities = 38/181 (20%), Positives = 95/181 (52%), Gaps = 19/181 (10%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
WR+ + E+E EK ++E+ W +++ + ++ +E+ ++ + + +I++
Sbjct: 539 WRQKEKIHEQE-EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ 597
Query: 284 KE------------EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEV 331
+E EEK ++ EK + E K +EQE K ++++ ++ ++EE++
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 332 RQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQASKNTE 388
R+Q + +++ ++K ++E + K++E E++R+++E E E R+RQ + +
Sbjct: 658 REQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Query: 389 K 389
+
Sbjct: 715 E 715
Score = 58.5 bits (140), Expect = 2e-08
Identities = 36/164 (21%), Positives = 91/164 (55%), Gaps = 10/164 (6%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRI--- 280
WR+ + ++E EK ++E+ W +++ + ++ +E+ +IR + + ++
Sbjct: 560 WRQEEKMHDQE-EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ 618
Query: 281 --KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL-EAARLAKEKEEEEVRQQALL 337
K ++EEK +++ EK + E K +EQE K ++++ ++ E + +E+EE+ Q+ +
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 678
Query: 338 AKKEKDIQKKAIKKERQKLR---NSCKIEEINEQIRKEKEEAEA 378
++E+ +Q++ K RQ+ + ++ + E++++ +E EA
Sbjct: 679 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 56.2 bits (134), Expect = 8e-08
Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 13/178 (7%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQN-------RATRAQRKKEEMNRIRTLVDNAYSC 276
WR+ + E+E EK ++E+ W +++ R ++++EEM R +
Sbjct: 480 WRQEEKIREQE-EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 277 DPRIKKFKE-EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQA 335
+ +K E EEK +K+ EK + E K +QE K ++++ ++ ++EE++R+Q
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 336 LLAKKEKDIQKKAIKKERQKLRNSC----KIEEINEQIRKEKEEAEARMRQASKNTEK 389
++++++ ++ +K ++ C K++E E++R+++E+ + ++ + EK
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/179 (24%), Positives = 96/179 (53%), Gaps = 13/179 (7%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRK-KEEMNRIRTLVDNAYSCDPRI---KKFKEE 286
+E+ +E+ + R++ + E++ + R + K +E+ +IR + + + +I +K +EE
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 287 EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQK 346
EK ++E E+ + E K +EQE +Q++ E +++EE+ RQ+ + +E+ I++
Sbjct: 517 EK-RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Query: 347 KAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDD 405
+ K RQ+ E+I EQ K +E+ E ++R+ + T++ G + E +
Sbjct: 576 QEEKVWRQE-------EKIREQEEKIREQ-EEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Score = 49.7 bits (117), Expect = 7e-06
Identities = 34/130 (26%), Positives = 74/130 (56%), Gaps = 12/130 (9%)
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL-EAARLAKEKEEEEVRQQALLAK 339
K +++EEK ++ EK + E K +EQE K ++++ ++ + EKEE+ RQ+ ++ +
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 340 KEKDI--QKKAIKKERQKLRNSCKIEEINEQIR--KEKEEAEARMRQASKNTEKSTGGGG 395
KE+ + Q++ + ++ +K+R + E+IR +EK + E ++R+ K E+
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE----- 476
Query: 396 NGSKNWSEDD 405
+K W +++
Sbjct: 477 --AKMWRQEE 484
Score = 47.4 bits (111), Expect = 4e-05
Identities = 39/157 (24%), Positives = 83/157 (52%), Gaps = 13/157 (8%)
Query: 241 RDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE-----EEKAKKEAEK 295
++E+ W +++ ++ +E+ +IR + + ++++ +E EEK +++ E
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 418
Query: 296 KAKAEAKRKEQE--AKEKQRQ-AELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKE 352
+ E K + QE EK+ + ELE K E+E++R+Q ++E+ I+++ K++
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQE-KRQ 473
Query: 353 RQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
Q+ + + E+I EQ K +E+ E RQ K E+
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Score = 43.5 bits (101), Expect = 5e-04
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 231 DEEEK---EKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEE 287
++EEK ++ + R++ + I +Q R Q + + + C+ K ++EE
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAA 320
K +++ EK + E + ++QE K ++ Q LEAA
Sbjct: 691 KMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 37.4 bits (85), Expect = 0.037
Identities = 40/160 (25%), Positives = 80/160 (50%), Gaps = 30/160 (18%)
Query: 231 DEEEKEK-AECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
DEE KEK A+ +++ + +E + + Q +E+ R K + +
Sbjct: 277 DEELKEKNAKLQEKLQLVESEK--SEIQLNVKELKR----------------KLERAKLL 318
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAA----RLAKEKEEEEVRQQALLAKKEKDIQ 345
+ + +A+A+ KE ++ + QA++E RL +++EE+ RQ+ + + E+ IQ
Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 378
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQ 382
++ K Q+ KI E E++R+++E E E +MR+
Sbjct: 379 EQEEKIREQEE----KIREQEEKMRRQEEMMWEKEEKMRR 414
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/259 (23%), Positives = 121/259 (46%), Gaps = 17/259 (6%)
Query: 234 EKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEA 293
E+ + +E R +E+Q +A A++ K ++ L + R ++ ++E + +KE
Sbjct: 460 ERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKEL 519
Query: 294 EKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKER 353
EK+ + E R+++ K+++RQ E E L KE+E++ ++ +KEK++++ +KE+
Sbjct: 520 EKEQEQE--REKEREKDRERQQEKE-KELEKEQEKQREMEKERKQEKEKELER---QKEK 573
Query: 354 QKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAV 413
+K K +E ++ KE+E+ E ++ N E K SE+ + V
Sbjct: 574 EKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMV------EKQESENSCNKEEEPV 627
Query: 414 NLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDP----HQKDDINKKAF 469
S E SG + + G K QK P Q++ + ++ +
Sbjct: 628 FTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQW 687
Query: 470 DKFKKEHGVVPQADNATPS 488
+ +++ GV+PQ + PS
Sbjct: 688 QQ-QQQQGVLPQTVPSQPS 705
Score = 57.8 bits (138), Expect = 3e-08
Identities = 41/147 (27%), Positives = 79/147 (53%), Gaps = 5/147 (3%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
EE+ KA C ++ + ++++ Q EE+ + + ++K +E+E+ K+
Sbjct: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER--EKEREREKELEKEQEQEREKER 531
Query: 293 AEKKAKAEAKRKEQEAK-EKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKA-IK 350
+ + + + K KE E + EKQR+ E E + KEKE E +++ +K K+ +K+ ++
Sbjct: 532 EKDRERQQEKEKELEKEQEKQREMEKE-RKQEKEKELERQKEKEKELQKMKEQEKECELE 590
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAE 377
KER+KL + E N + EK+E+E
Sbjct: 591 KEREKLEEKIEPREPNLEPMVEKQESE 617
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 32/168 (19%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
+E E+E+EK +D R EK+ + Q K+ EM +
Sbjct: 517 KELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM--------------------E 556
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+E K +KE E + + E +++ Q+ KE++++ ELE R EK EE++ +E ++
Sbjct: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKER---EKLEEKIE------PREPNL 607
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTG 392
+ E+Q+ NSC EE R++ +E TE +G
Sbjct: 608 EPMV---EKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESG 652
Score = 35.4 bits (80), Expect = 0.14
Identities = 45/236 (19%), Positives = 97/236 (41%), Gaps = 23/236 (9%)
Query: 278 PRIKKFKEEE------KAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEV 331
P +KF E K ++ EK + + + + A + Q + A + +EK+ E+V
Sbjct: 1082 PEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKV 1141
Query: 332 RQQALLAKKEKDIQKKAIKKE-----RQKLRNSCKIEEINEQIRKEKEEAEARMRQASKN 386
+ L+ ++ + + A+KKE R + + + + +Q + + E R ++
Sbjct: 1142 ISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSR--GRS 1199
Query: 387 TEKSTGGGGNGSKNWSEDDLQLLIK--AVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAK 444
S GG G G + + D Q P+G + E S + + +
Sbjct: 1200 YRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQRE--------ESETRSESSDF 1251
Query: 445 DVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPYTDFTP 500
+V+ K + + + +I++ A DK G +P+ + +++ P++ F P
Sbjct: 1252 EVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKP 1307
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 64.3 bits (155), Expect = 3e-10
Identities = 47/199 (23%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
W + R + E++EK ++E W +++ + + E+ +IR L + + +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAK-----EKQRQAELEAARLAKE--KEEEE 330
K +E+E+ K++ E+K + + KR+EQEAK EK R+ E + K+ ++EE+
Sbjct: 405 ----KIREQEE-KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 331 VRQQALLAKKEKDIQKKAIKKERQKLRNSCKI----EEINEQIRKEKEEAEARMRQASKN 386
+ +Q + ++EK +++ + ++ +K+ +I E+++EQ K +++ E RQ K
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 387 TEKSTGGGGNGSKNWSEDD 405
E+ K W +++
Sbjct: 520 REQEEKIREQEEKMWRQEE 538
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/173 (24%), Positives = 91/173 (52%), Gaps = 14/173 (8%)
Query: 222 DSWREFSYLDEEEK----EKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
+ WRE + E+EK EK + ++++ W +++ + ++ + +IR +
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR---------E 595
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL-EAARLAKEKEEEEVRQQAL 336
K+ ++EEK K+ EK + E K +EQE K ++++ ++ E + +E+EE+ Q+
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 337 LAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+ ++E+ +Q++ RQ+ + + ++I EQ K +E+ E Q K E+
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708
Score = 57.8 bits (138), Expect = 3e-08
Identities = 51/201 (25%), Positives = 98/201 (48%), Gaps = 19/201 (9%)
Query: 222 DSWREFSYLDEEE---KEKAECRDERRWIEKQNRATRAQRKK--EEMNRIRTLVDNAYSC 276
+ WR+ + E+E ++K + ++ I KQ Q +K E+ +IR + +
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 277 DPRIKKFKE--EEKAKKEAEKKAKAEAKRKEQEAK-----EKQRQAELEAARLA---KEK 326
+ +I++ +E E+ K ++K E KR+EQE K EK R+ E + R +E+
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
Query: 327 EEEEVRQQALLAKKEKDI--QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQAS 384
EE+ Q+ + K+E+ I Q++ I+++ +K+R + E+I EQ +E+ E Q
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE--QEEKIREQEEMTQEQEEKMGEQEE 654
Query: 385 KNTEKSTGGGGNGSKNWSEDD 405
K E+ W +++
Sbjct: 655 KMCEQEEKMQEQEETMWRQEE 675
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/177 (24%), Positives = 89/177 (50%), Gaps = 20/177 (11%)
Query: 224 WREFSYLDEEEKEKAECRDERRW-----IEKQNRATRAQRKKEEMNRI------RTLVDN 272
WR+ + E+E EK ++E+ W I +Q R + K E +I + D
Sbjct: 513 WRQEEKIREQE-EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Query: 273 AYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVR 332
+ + +I++ +EEK ++ EK + E KR+EQE K +++ ++ +++EE++R
Sbjct: 572 MWRQEEKIRE--QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Query: 333 QQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+Q ++++++ ++ +K ++ C+ EE K +E+ E RQ K E+
Sbjct: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE------KMQEQEETMWRQEEKIREQ 680
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/173 (20%), Positives = 94/173 (54%), Gaps = 17/173 (9%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
WR+ + E+E+++ E ++E+ W +++ + ++ +E+ +IR + K
Sbjct: 587 WRQEEKIREQEEKRQE-QEEKMWKQEEKIREQEEKIQEQEEKIR---------EQEEKIR 636
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
++EE +++ EK + E K EQE K ++++ + ++E+++R+Q +++++
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 344 IQKKAIKKERQKLRNSC----KIEEINEQIRKEKE---EAEARMRQASKNTEK 389
+ ++ +K ++ C K++E E++R+++E E E R+RQ + ++
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/187 (24%), Positives = 93/187 (49%), Gaps = 17/187 (9%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRK-KEEMNRIRTLVDNAYSCDPRI---KKFKEE 286
+E+ +E+ + R++ + E++ + R + K +E+ +IR + + +I +K +EE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 287 EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQK 346
EK ++E E+ + E K EQE +Q++ E +++EE+ RQ+ + ++E+ I++
Sbjct: 470 EK-RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 347 KAIKKERQKLRNSCKIEEINEQIRKEKE--------EAEARMRQASKNTEKSTGGGGNGS 398
+ K RQ+ KI E E R+E++ E E R Q K +
Sbjct: 529 QEEKMWRQEE----KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEE 584
Query: 399 KNWSEDD 405
K W +++
Sbjct: 585 KVWRQEE 591
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/167 (20%), Positives = 88/167 (52%), Gaps = 8/167 (4%)
Query: 230 LDEEEKEKAECRDER--RWIEK---QNRATRAQRKK--EEMNRIRTLVDNAYSCDPRIKK 282
L+++++EK ++E+ W EK Q R Q +K E+ ++R + + + ++++
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
+EE +KE + + + E +++E +Q + E +E EE+ Q+ + ++EK
Sbjct: 354 -QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+++ I+++ ++ K+ E+IR+++E+ + ++ + EK
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Score = 47.0 bits (110), Expect = 5e-05
Identities = 42/209 (20%), Positives = 98/209 (46%), Gaps = 27/209 (12%)
Query: 171 KSEAKDNFFEVFTPVFERNSR-WSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSY 229
+ E +D + + E+ + W ++ + + + E+ W + RE
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-----KMWKQEEKIREQEE 619
Query: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
+E++EK R++ I +Q T+ Q +K + K ++EEK
Sbjct: 620 KIQEQEEKI--REQEEKIREQEEMTQEQEEK--------------MGEQEEKMCEQEEKM 663
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAEL-EAARLAKEKEEEEVRQQALLAKKEKDIQKKA 348
+++ E + E K +EQE K ++++ ++ E + +E+EE+ Q+ + ++E+ +Q++
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
Query: 349 IKKERQKLRNSCKIEEINEQIRKEKEEAE 377
K RQ+ K+ E ++R+++E+ +
Sbjct: 724 EKMRRQEE----KMWEQEVRLRQQEEKMQ 748
Score = 36.6 bits (83), Expect = 0.063
Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 15/183 (8%)
Query: 231 DEEEKEK-AECRDERRWIEKQNRATRAQRK--KEEMNRIRTLVDNAYSCDPRIKKFKEEE 287
DEE KEK A+ +++ + +E + + K K ++ R + L+ P+ + E +
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL-------PQQQLQAEAD 268
Query: 288 KAKKEAEK-KAKAEAKRKEQEAKEKQRQAELEAARLAKEK----EEEEVRQQALLAKKEK 342
KE + AK +A+ +E E + Q + E +EK EE+ Q+ + ++E+
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWS 402
I+++ K RQ+ K E++ Q E+ E RQ EK W
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 403 EDD 405
+++
Sbjct: 389 KEE 391
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 63.5 bits (153), Expect = 5e-10
Identities = 45/165 (27%), Positives = 90/165 (54%), Gaps = 13/165 (7%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E++EK ++E W +++ + + E+ +IR L + + + K +E+E+ K++
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE----KIREQEE-KRQ 367
Query: 293 AEKKAKAEAKRKEQEAK-----EKQRQAE---LEAARLAKEKEEEEVRQQALLAKKEKDI 344
E+K + + KR+EQEAK EK R+ E E + +E+EE+ Q+ + ++E+++
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
Q++ K RQ+ + + ++I EQ K +E+ E Q K E+
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Score = 62.8 bits (151), Expect = 8e-10
Identities = 36/172 (20%), Positives = 95/172 (55%), Gaps = 9/172 (5%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE + +E++EK ++E+ W +++ + ++ + + +IR + +I++
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE-- 457
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+EE +++ EK + E K EQEAK ++++ ++ ++E+++R+Q ++++++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 345 QKKAIKKERQKLRNSC----KIEEINEQIRKEKE---EAEARMRQASKNTEK 389
++ +K ++ C K++E E++R+++E E E R+RQ + ++
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 50.4 bits (119), Expect = 4e-06
Identities = 33/166 (19%), Positives = 89/166 (53%), Gaps = 7/166 (4%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRK-KEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
+E+ +E+ + R++ + E++ + R + K +E+ +IR + + ++ + +E+
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAE------LEAARLAKEKEEEEVRQQALLAKKEKD 343
++E ++ + + +R+E++ +E++++ E + +E+EE+ Q+ + ++E
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+Q++ K RQ+ + + ++I EQ K +E+ E Q K E+
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 528
Score = 48.5 bits (114), Expect = 2e-05
Identities = 37/173 (21%), Positives = 85/173 (49%), Gaps = 17/173 (9%)
Query: 235 KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAE 294
K +A+ + W NR Q+++E+M R + R +K +E+E+ +E E
Sbjct: 268 KLQAQVEENELW----NRLN--QQQEEKMWRQEEKIQE------REEKIQEQEEKIREQE 315
Query: 295 KKAKAEAKRKEQEAKEKQRQAEL--EAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKE 352
+K + + + ++ ++ +RQ E+ E +E EE+ Q+ + ++EK +++ I+++
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 353 RQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDD 405
++ K+ E+IR+++E+ + + EK G K W +++
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM---GEQEEKMWEQEE 425
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/160 (21%), Positives = 80/160 (50%), Gaps = 18/160 (11%)
Query: 224 WREFSYLDEEE----KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279
W + + E+E +++ + R++ + I +Q R Q + + + C+
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQE--AKEKQRQAELEAARLAKEKEEEEVRQQALL 337
K ++EEK +++ EK + E K +EQE +E++ + +E+EE+ Q+ +
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE--------EMMQEQEEKMWEQEEKM 532
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAE 377
++E+ +Q++ K RQ+ K+ E ++R+++E+ +
Sbjct: 533 CEQEEKMQEQEEKMRRQEE----KMREQEVRLRQQEEKMQ 568
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/171 (22%), Positives = 87/171 (50%), Gaps = 10/171 (5%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
W + EE+ + E + + R + Q + + + ++E+M R ++ + K
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM-----WEKEEKMR 333
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEA--KEKQRQAELEAARLAKEKEEEEV---RQQALLA 338
++EE ++ EK + E K EQE ++++++ E E R ++++E+E RQ+ +
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 339 KKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++E+ I+++ + Q+ + + E++ EQ + +E+ E RQ K E+
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/195 (20%), Positives = 98/195 (50%), Gaps = 28/195 (14%)
Query: 231 DEEEKEK-AECRDERRWIEKQNRATRAQRK--KEEMNRIRTLVDNAY------------- 274
DEE KEK A+ +++ + +E + + K K ++ R + L+
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 275 SCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ 334
S +++ EE + ++ + + R+E++ +E++ + + + ++ +E+EE+ RQ+
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI-REQEEKMRRQE 322
Query: 335 ALLAKKEKDI--QKKAIKKERQKLRNSCKIEEINEQIR--KEKEEAEARMRQASKNTEKS 390
++ +KE+ + Q++ + ++ +K+R + E+IR +EK + E ++R+ K E+
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 382
Query: 391 TGGGGNGSKNWSEDD 405
+K W +++
Sbjct: 383 -------AKMWRQEE 390
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 63.2 bits (152), Expect = 6e-10
Identities = 65/255 (25%), Positives = 115/255 (45%), Gaps = 22/255 (8%)
Query: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
++EE+KE+AE R E++ R Q KK R R + + R ++ EE +
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI 349
+E EK+A E Q KE++++A E R+ KE+E+ ++ + ++EK ++
Sbjct: 317 MREEEKRAAEE----RQRIKEEEKRAAEERQRI-KEEEKRAAEERQRIKEEEKRAAEER- 370
Query: 350 KKERQKLRNSCKIEE--INEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQ 407
++ R + K+EE N+Q+ +EK+ A + + E+ G K ED LQ
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQL-EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429
Query: 408 LLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDI--- 464
+ L G +V A + K T K K + ++K D K+++
Sbjct: 430 TAV----LKKQGEEKGTKVQAKREKLQED---KPTFKKEEIKDEKIKK-DKEPKEEVKSF 481
Query: 465 --NKKAFDKFKKEHG 477
KK F + K ++G
Sbjct: 482 MDRKKGFTEVKSQNG 496
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 19/183 (10%)
Query: 226 EFSYLDEEEKEKAECR------DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279
E + L+ EE+E+ + DER IE + +A +R++ E + +
Sbjct: 268 ERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEE 327
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKR---KEQEAKEKQRQAELEAARLAKEKEE----EEVR 332
++ KEEEK E ++ K E KR + Q KE++++A E R E+EE EE +
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Query: 333 QQALLAKKEKDIQKKAIKKER--QKLR----NSCKIEEINEQIRKEKEEAEARMRQASKN 386
+ L +K+ +Q+ IK E+ QK+ N K +E Q K++ E + +
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAK 447
Query: 387 TEK 389
EK
Sbjct: 448 REK 450
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/186 (27%), Positives = 93/186 (50%), Gaps = 34/186 (18%)
Query: 226 EFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIK---- 281
E + ++ EEK A+ R+ R E++ +R EE RI+ A RIK
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 350
Query: 282 -------KFKEEEK--------AKKEAEKKAKAEAKRKEQEAKEKQR------------Q 314
+ KEEEK A+ E E+KAK E +++ ++ +EK+ +
Sbjct: 351 RAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Query: 315 AELEAARLAKEKEEEEVRQQALLAK--KEKDIQKKAIKKERQKLRNSCKIEEI-NEQIRK 371
++E + ++K +E+ Q A+L K +EK + +A +++ Q+ + + K EEI +E+I+K
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 372 EKEEAE 377
+KE E
Sbjct: 471 DKEPKE 476
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/245 (23%), Positives = 109/245 (44%), Gaps = 32/245 (13%)
Query: 161 DPTFDN---SVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSF 217
DPT + S+PS+ D T E++ + + + + S++ D
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND----- 176
Query: 218 WYNFDSWR--EFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYS 275
WR E + +++EKE+ E +R +N+ +K ++ T+V + +
Sbjct: 177 ------WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Query: 276 CDPRIKKFKEEEK-----------AKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAK 324
++ K+EE+ K E E K +AEA+R EA+E++R + ++A
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 325 EKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQAS 384
E+ E ++A ++E+ ++A +ER+++R K Q KE+E+ A RQ
Sbjct: 291 ERARIEAEEKAAAQERER---REA--EERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 385 KNTEK 389
K EK
Sbjct: 346 KEEEK 350
Score = 53.1 bits (126), Expect = 7e-07
Identities = 43/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
KEAE + EA ++ +E + ++ + E E K+K++E + L KK+++ ++K ++
Sbjct: 522 KEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEEL-KKKREERRKVLE 580
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLI 410
+E Q+ K EE + ++R+E+E+ R+ + E+ + ED L
Sbjct: 581 EEEQRR----KQEEADRKLREEEEK-----RRLKEEIERRRAEAAEKRQKMPEDGLSDDK 631
Query: 411 KAVNLF-PAGTNSRWEVIANYMN--IHSSSGVKRTAKDVI 447
K F P G++ + E A ++N + SSGVK T + I
Sbjct: 632 KPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAI 671
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 12/172 (6%)
Query: 230 LDEEEKEKAECR-----DERRWIEKQNRATRAQRKK-EEMNRIRTLVDNAYSCDPRIKKF 283
+ EEEK AE R +E+R E++ R +++ EE R R + + + +
Sbjct: 331 IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNK 390
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAK----EKQRQAELEAARLAKEKEEEEVRQQALLAK 339
+ EEK E K K E ++ E K +K ++ +L+ A L K+ EE+ + QA K
Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450
Query: 340 KEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKST 391
++D K KKE K K +E E+++ + + S+N E T
Sbjct: 451 LQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT 500
Score = 44.3 bits (103), Expect = 3e-04
Identities = 82/358 (22%), Positives = 147/358 (41%), Gaps = 62/358 (17%)
Query: 39 VKRRNRNASASFQEL-EDKKELSEE------SEDEELQLEEFPMLKTLDPKDWKNQDHYA 91
+K + A+ Q + E++K +EE E+E+ ++EE K L+ K Q+
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE--- 401
Query: 92 VLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDP 151
+ K + + K K + K + + K+G+ TK
Sbjct: 402 ------TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKG----TKVQ------ 445
Query: 152 VKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFT-PVFERNSRWSNKKNVPKLGDMNSSFED 210
KR PTF K E KD + P E S KK ++ N F
Sbjct: 446 AKREKLQEDKPTF-----KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT 500
Query: 211 VDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLV 270
+ ++ F + +D +E E A + + +E+ R R + + EE ++
Sbjct: 501 HKLKHTE-NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR-RGETESEEFEKL---- 554
Query: 271 DNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE-- 328
K K++E A + E K K E +RK E +E++R+ E EA R +E+EE
Sbjct: 555 -----------KQKQQEAALELEELKKKREERRKVLEEEEQRRKQE-EADRKLREEEEKR 602
Query: 329 ---EEV-RQQALLAKKEKDIQKKAIKKERQKLR------NSCKIEEINEQIRKEKEEA 376
EE+ R++A A+K + + + + +++ + +S KIEE E + K +++
Sbjct: 603 RLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS 660
Score = 39.3 bits (90), Expect = 0.010
Identities = 35/175 (20%), Positives = 76/175 (43%), Gaps = 33/175 (18%)
Query: 231 DEEEKE-----KAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
DEE K + E DE ++E+ A+R++ R++ ++ DP I
Sbjct: 76 DEEAKTTTTNTQVEGDDEAAFLERL-----ARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLA---------------------K 324
+++ A+ E KE++++ +Q + E+E K
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 325 EKEEEEVRQQALLAKKEKD--IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAE 377
E+EEEE ++ + + + + +++K + + + + S K +I+ + K++EE E
Sbjct: 191 EEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEERE 245
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/76 (22%), Positives = 39/76 (51%)
Query: 302 KRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCK 361
+R+ + ++K+ + LEA R+A ++ +++ + A ++ ++ K+E + L
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 362 IEEINEQIRKEKEEAE 377
E+N Q EEA+
Sbjct: 65 QVEVNAQNSVPDEEAK 80
Score = 30.8 bits (68), Expect = 3.5
Identities = 26/106 (24%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQE-AKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
++ E+ + EAE+ A E+E A+E++R+A E RL +++EEE + Q + + E
Sbjct: 13 QKREEMRLEAERIAYQRNDDDEEEAARERRRRARQE--RLRQKQEEESLGQ--VTDQVEV 68
Query: 343 DIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQA 383
+ Q +E + + ++E E++ + +E + R+++A
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEA 114
Score = 30.4 bits (67), Expect = 4.5
Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+EE+A +E ++A+ E R++QE + + + +EE + + E D
Sbjct: 33 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD- 91
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
+A ER R + + + E + ++KE
Sbjct: 92 -DEAAFLERLARREERRQKRLQEALERQKE 120
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 62.8 bits (151), Expect = 8e-10
Identities = 65/379 (17%), Positives = 161/379 (42%), Gaps = 40/379 (10%)
Query: 27 QVEPVGRWFEAFVKRRN--RNASASFQELEDKKELSEES---------EDEELQLEEFPM 75
Q E + W E ++ R +E E+K EE EE+ E+
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 76 LKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDN 135
++ L+ W+ ++ L + + Q + + ++ +++ + ++ +
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 136 DYFTCITKAYEMLSDPVKR--RAFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWS 193
I + E + + K+ R + K + ++ + + E+ W
Sbjct: 425 -----IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 194 NKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRA 253
K+ + + + E V WR+ + ++E EK ++E+ W +++
Sbjct: 480 QKEKMHEQEKIRKQEEKV------------WRQEEKMHDQE-EKIREQEEKMWRQEEKIR 526
Query: 254 TRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQR 313
+ ++ +E+ +IR + + +K E+E+ +E EK + E K +EQE K +++
Sbjct: 527 EQEEKIREQEEKIR---EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Query: 314 QAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEK 373
+ ++ ++EE++R+Q + +++ ++K ++E + K++E E++R+++
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 374 E---EAEARMRQASKNTEK 389
E E E R+RQ + ++
Sbjct: 641 EKMWEQEVRLRQQEEKMQE 659
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/192 (23%), Positives = 94/192 (48%), Gaps = 17/192 (8%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
W + R + E++EK +E W EK+ + + K E +IR
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMW-EKEEKIRELEEKMHEQEKIRE--------- 394
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
+ +K +EEEK + E EK+ + EAK QE K ++++ ++ ++EE++ +Q +
Sbjct: 395 -QEEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 452
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKI----EEINEQIRKEKEEAEARMRQASKNTEKSTGG 393
++EK +++ + ++ +K+R +I E+++EQ + K+E E RQ K ++
Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE-EKVWRQEEKMHDQEEKI 511
Query: 394 GGNGSKNWSEDD 405
K W +++
Sbjct: 512 REQEEKMWRQEE 523
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/193 (25%), Positives = 95/193 (49%), Gaps = 18/193 (9%)
Query: 222 DSWREFSYLDEEEK--EKAECRDERRWIEKQNRATRAQRKK--EEMNRIRTLVDNAYSCD 277
+ WR+ + E+E+ + E E+ I KQ Q +K ++ +IR + + +
Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAK---EKQRQAELEAARLAKEK---EEEEV 331
+I++ +EEK +++ EK + E +EQE K ++++ E E R +EK +EE++
Sbjct: 523 EKIRE--QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 332 RQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKST 391
R+Q K++ Q++ I ++ +K+R + E + EQ K E+ E Q K E+
Sbjct: 581 REQ----KEKIREQEEKIWEQEEKIRE--QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 392 GGGGNGSKNWSED 404
K W ++
Sbjct: 635 KMRRQEEKMWEQE 647
Score = 50.8 bits (120), Expect = 3e-06
Identities = 61/307 (19%), Positives = 137/307 (44%), Gaps = 34/307 (11%)
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL-EAARLAKEKEEEEVRQQALLAK 339
K +++EEK ++ EK + E K +EQE K ++++ ++ + EKEE+ RQ+ ++ +
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 340 KEKDIQK--KAIKKERQKLRNSCKIEEINEQIR--KEKEEAEARMRQASKNTEKSTGGGG 395
KE+ +++ + + ++ +K+R + E+IR +EK + E ++R+ K E+
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE----- 415
Query: 396 NGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAK----------- 444
+K W ++ + + + W IH ++ K
Sbjct: 416 --AKMWRQE--EKIREQEEKIREQEKKMWR---QEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 445 DVIGKAKSL--QKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPYTDFTPWT 502
+ I + + + QK H+++ I K+ +++E + Q + E E +
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE--EKMWRQEEKIR 526
Query: 503 TEEQKLLEQ--ALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQV 560
+E+K+ EQ ++ E+ EK+ E +++ M+R +E + + K Q++
Sbjct: 527 EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
Query: 561 LNASRAK 567
+ K
Sbjct: 587 IREQEEK 593
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/170 (22%), Positives = 81/170 (47%), Gaps = 28/170 (16%)
Query: 230 LDEEEKEKAECRDER--RWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEE 287
L+++++EK ++E+ W EK R++EE R ++EE
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR------------------EQEE 335
Query: 288 KAKKEAEKKAKAEAKRKEQEA-----KEKQRQAE---LEAARLAKEKEEEEVRQQALLAK 339
K +++ E + E K + QE +EK R+ E E +E EE+ Q+ + +
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 340 KEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+EK +++ I+++ ++ K+ E+IR+++E+ + ++ + EK
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E+KEK ++E+ W +Q R Q + + + C+ K ++EEK +++
Sbjct: 582 EQKEKIREQEEKIW--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAA 320
EK + E + ++QE K ++ Q LEAA
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 37.4 bits (85), Expect = 0.037
Identities = 40/160 (25%), Positives = 80/160 (50%), Gaps = 30/160 (18%)
Query: 231 DEEEKEK-AECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
DEE KEK A+ +++ + +E + + Q +E+ R K + +
Sbjct: 216 DEELKEKNAKLQEKLQLVESEK--SEIQLNVKELKR----------------KLERAKLL 257
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAA----RLAKEKEEEEVRQQALLAKKEKDIQ 345
+ + +A+A+ KE ++ + QA++E RL +++EE+ RQ+ + + E+ IQ
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQ 382
++ K Q+ KI E E++R+++E E E +MR+
Sbjct: 318 EQEEKIREQEE----KIREQEEKMRRQEEMMWEKEEKMRR 353
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 62.8 bits (151), Expect = 8e-10
Identities = 44/161 (27%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E+ +AE R +R E++ R +R++EE+ R + + + + + K+EE ++
Sbjct: 732 EQERREAEMRAKREE-EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 790
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAE-LEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E++ A R+++E +E+Q+Q E L + +EEE +Q+ LL K+E++ K A +
Sbjct: 791 QREQEI---ALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 847
Query: 351 KERQKLR---NSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+E + R N ++EE ++R E+EE + + + + E
Sbjct: 848 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 888
Score = 59.7 bits (143), Expect = 7e-09
Identities = 41/158 (25%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Query: 231 DEEEKEKAECRDERRWI-EKQNRATRAQRKKEEMNRIRT--LVDNAYSCDPRIKKFKEEE 287
+EE K + E R ++ I +Q R +R++EE+ R + + + +++ +EEE
Sbjct: 746 EEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEE 805
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQ----RQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+ +++ E + E +R+E+E + KQ R+ E EAA+ A+E+EE + R + + E++
Sbjct: 806 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 865
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMR 381
+ ++E +K R +++ E +R+ +++ EA R
Sbjct: 866 AARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR 902
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/152 (28%), Positives = 86/152 (56%), Gaps = 20/152 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E+ + A+ ERR E + + +RK++E R + + +++ +EEE+ ++E
Sbjct: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ--------EEILRRQQEEERKRRE 775
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ--ALLAKKEKDIQKKAIK 350
E+ A+ RK++EA +QR+ E+ L +++EEEE +QQ AL +E+ +++ +
Sbjct: 776 EEELAR----RKQEEALRRQREQEIA---LRRQREEEERQQQEEALRRLEERRREEEERR 828
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
K+ + LR K EE + +E+EEA+ R+ +
Sbjct: 829 KQEELLR---KQEEEAAKWAREEEEAQRRLEE 857
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/117 (25%), Positives = 64/117 (54%), Gaps = 10/117 (8%)
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
P +++ ++ EKAK AK E +R+E E + K+ + E + + ++EE +R+Q
Sbjct: 715 PALEQLQQLEKAKA-----AKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE 769
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQASKNTEK 389
+K ++ ++ A +K+ + LR + E + E+ R+++EEA R+ + + E+
Sbjct: 770 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 826
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 62.8 bits (151), Expect = 8e-10
Identities = 44/161 (27%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E+ +AE R +R E++ R +R++EE+ R + + + + + K+EE ++
Sbjct: 759 EQERREAEMRAKREE-EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 817
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAE-LEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E++ A R+++E +E+Q+Q E L + +EEE +Q+ LL K+E++ K A +
Sbjct: 818 QREQEI---ALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 874
Query: 351 KERQKLR---NSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+E + R N ++EE ++R E+EE + + + + E
Sbjct: 875 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915
Score = 59.7 bits (143), Expect = 7e-09
Identities = 41/158 (25%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Query: 231 DEEEKEKAECRDERRWI-EKQNRATRAQRKKEEMNRIRT--LVDNAYSCDPRIKKFKEEE 287
+EE K + E R ++ I +Q R +R++EE+ R + + + +++ +EEE
Sbjct: 773 EEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEE 832
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQ----RQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+ +++ E + E +R+E+E + KQ R+ E EAA+ A+E+EE + R + + E++
Sbjct: 833 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 892
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMR 381
+ ++E +K R +++ E +R+ +++ EA R
Sbjct: 893 AARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR 929
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/152 (28%), Positives = 86/152 (56%), Gaps = 20/152 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E+ + A+ ERR E + + +RK++E R + + +++ +EEE+ ++E
Sbjct: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ--------EEILRRQQEEERKRRE 802
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ--ALLAKKEKDIQKKAIK 350
E+ A+ RK++EA +QR+ E+ L +++EEEE +QQ AL +E+ +++ +
Sbjct: 803 EEELAR----RKQEEALRRQREQEIA---LRRQREEEERQQQEEALRRLEERRREEEERR 855
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
K+ + LR K EE + +E+EEA+ R+ +
Sbjct: 856 KQEELLR---KQEEEAAKWAREEEEAQRRLEE 884
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/117 (25%), Positives = 64/117 (54%), Gaps = 10/117 (8%)
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
P +++ ++ EKAK AK E +R+E E + K+ + E + + ++EE +R+Q
Sbjct: 742 PALEQLQQLEKAKA-----AKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE 796
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQASKNTEK 389
+K ++ ++ A +K+ + LR + E + E+ R+++EEA R+ + + E+
Sbjct: 797 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 853
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 62.8 bits (151), Expect = 8e-10
Identities = 44/161 (27%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E+ +AE R +R E++ R +R++EE+ R + + + + + K+EE ++
Sbjct: 738 EQERREAEMRAKREE-EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAE-LEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E++ A R+++E +E+Q+Q E L + +EEE +Q+ LL K+E++ K A +
Sbjct: 797 QREQEI---ALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 853
Query: 351 KERQKLR---NSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+E + R N ++EE ++R E+EE + + + + E
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
Score = 59.7 bits (143), Expect = 7e-09
Identities = 41/158 (25%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Query: 231 DEEEKEKAECRDERRWI-EKQNRATRAQRKKEEMNRIRT--LVDNAYSCDPRIKKFKEEE 287
+EE K + E R ++ I +Q R +R++EE+ R + + + +++ +EEE
Sbjct: 752 EEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEE 811
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQ----RQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+ +++ E + E +R+E+E + KQ R+ E EAA+ A+E+EE + R + + E++
Sbjct: 812 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 871
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMR 381
+ ++E +K R +++ E +R+ +++ EA R
Sbjct: 872 AARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR 908
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/152 (28%), Positives = 86/152 (56%), Gaps = 20/152 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E+ + A+ ERR E + + +RK++E R + + +++ +EEE+ ++E
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ--------EEILRRQQEEERKRRE 781
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ--ALLAKKEKDIQKKAIK 350
E+ A+ RK++EA +QR+ E+ L +++EEEE +QQ AL +E+ +++ +
Sbjct: 782 EEELAR----RKQEEALRRQREQEIA---LRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
K+ + LR K EE + +E+EEA+ R+ +
Sbjct: 835 KQEELLR---KQEEEAAKWAREEEEAQRRLEE 863
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/117 (25%), Positives = 64/117 (54%), Gaps = 10/117 (8%)
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
P +++ ++ EKAK AK E +R+E E + K+ + E + + ++EE +R+Q
Sbjct: 721 PALEQLQQLEKAKA-----AKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE 775
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQASKNTEK 389
+K ++ ++ A +K+ + LR + E + E+ R+++EEA R+ + + E+
Sbjct: 776 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 832
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 62.8 bits (151), Expect = 8e-10
Identities = 44/161 (27%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E+ +AE R +R E++ R +R++EE+ R + + + + + K+EE ++
Sbjct: 738 EQERREAEMRAKREE-EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAE-LEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E++ A R+++E +E+Q+Q E L + +EEE +Q+ LL K+E++ K A +
Sbjct: 797 QREQEI---ALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 853
Query: 351 KERQKLR---NSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+E + R N ++EE ++R E+EE + + + + E
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
Score = 59.7 bits (143), Expect = 7e-09
Identities = 41/158 (25%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Query: 231 DEEEKEKAECRDERRWI-EKQNRATRAQRKKEEMNRIRT--LVDNAYSCDPRIKKFKEEE 287
+EE K + E R ++ I +Q R +R++EE+ R + + + +++ +EEE
Sbjct: 752 EEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEE 811
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQ----RQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+ +++ E + E +R+E+E + KQ R+ E EAA+ A+E+EE + R + + E++
Sbjct: 812 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 871
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMR 381
+ ++E +K R +++ E +R+ +++ EA R
Sbjct: 872 AARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR 908
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/152 (28%), Positives = 86/152 (56%), Gaps = 20/152 (13%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E+ + A+ ERR E + + +RK++E R + + +++ +EEE+ ++E
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ--------EEILRRQQEEERKRRE 781
Query: 293 AEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ--ALLAKKEKDIQKKAIK 350
E+ A+ RK++EA +QR+ E+ L +++EEEE +QQ AL +E+ +++ +
Sbjct: 782 EEELAR----RKQEEALRRQREQEIA---LRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
K+ + LR K EE + +E+EEA+ R+ +
Sbjct: 835 KQEELLR---KQEEEAAKWAREEEEAQRRLEE 863
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/117 (25%), Positives = 64/117 (54%), Gaps = 10/117 (8%)
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
P +++ ++ EKAK AK E +R+E E + K+ + E + + ++EE +R+Q
Sbjct: 721 PALEQLQQLEKAKA-----AKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE 775
Query: 338 AKKEKDIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQASKNTEK 389
+K ++ ++ A +K+ + LR + E + E+ R+++EEA R+ + + E+
Sbjct: 776 ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 832
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 62.8 bits (151), Expect = 8e-10
Identities = 42/160 (26%), Positives = 89/160 (55%), Gaps = 13/160 (8%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E+E+++ + E++ +K+ R +RK++E + R + R K+ ++ +K KK
Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK--------ERREKERRKRKKEKK 102
Query: 292 EAEKKAKAEAKRKEQ-EAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ E+K + +RK++ E KE++R+ + R K++ +++ R++ K+EK+ K+ K
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER---KREKERGKRERK 159
Query: 351 KERQKLRNSCKIEEINEQIRK-EKEEAEARMRQASKNTEK 389
++++K K E N + RK E+E E R R+ + E+
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
Score = 62.0 bits (149), Expect = 1e-09
Identities = 41/161 (25%), Positives = 89/161 (55%), Gaps = 21/161 (13%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+ + KE+ + R ERR EK+ R + ++KK E + R ++ K++E+ +
Sbjct: 76 ERKRKEREKQRKERR--EKERRKRKKEKKKRERKQ-----------RGRRERKKKKERKE 122
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+E E K + E KRK++ K+++++ + E R +E++ ++ +++ K+E++ +K K
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN--RKERK 180
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKST 391
KER++ + +E ++ RK+KE R+ + T++ T
Sbjct: 181 KERERKERRERKKERKKERRKKKE------RKKDRKTDRQT 215
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/158 (26%), Positives = 77/158 (48%), Gaps = 7/158 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E E++K E+R E++ R + KKE+ R R +K KE EK +K
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKR-----KKRERGKERERKRKEREKQRK 87
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
E++ K KRK+++ K +++Q + KE++E E + +K K +KK +K
Sbjct: 88 --ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 352 ERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
ER++ + K E ++ +KE+ E + + + E+
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Score = 59.3 bits (142), Expect = 9e-09
Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 21/155 (13%)
Query: 235 KEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAE 294
+ ++E + ERR EK+ R +RK+E + K+E+K +K+ E
Sbjct: 31 QRESERKKERREREKRKREREKERKRE--------------------RGKKEKKKRKKRE 70
Query: 295 KKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQ 354
+ + E KRKE+E + K+R+ E E + KEK++ E +Q+ +K+K +K+ ++ +Q
Sbjct: 71 RGKERERKRKEREKQRKERR-EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 355 KLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+ K ++ ++ K E E R+ + K
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRK 164
Score = 59.3 bits (142), Expect = 9e-09
Identities = 36/135 (26%), Positives = 72/135 (53%), Gaps = 1/135 (0%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE + EKE+ + + E++ E++ R R ++KK+E + ++ K
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+ K +K +++ K E KRK+++ +E++++ E KE+E +E R++ KKE+
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR- 200
Query: 345 QKKAIKKERQKLRNS 359
+KK KK+R+ R +
Sbjct: 201 KKKERKKDRKTDRQT 215
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/166 (25%), Positives = 82/166 (49%), Gaps = 5/166 (3%)
Query: 232 EEEKEKAECRDERRWIEKQNRAT-RAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
E KE+ R ER K+ R R +RKKE+ R R + +K +E E +
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI- 349
+ K+ K K++ +E K ++ + + E R ++KEE E +++ +++K+ ++K
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
Query: 350 --KKERQKLRNSCKIEEINEQIRKEKEEAEAR-MRQASKNTEKSTG 392
KKER+K R K + + + ++ + R +R+++ N TG
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTG 235
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/105 (23%), Positives = 64/105 (60%), Gaps = 4/105 (3%)
Query: 289 AKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQAL---LAKKEKDIQ 345
+K +++++ + +R+E+E ++++R+ E + R KEK++ + R++ +KE++ Q
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 346 KKAIK-KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+K + KER+K + K E ++ R+E+++ + R + +N ++
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130
Score = 40.0 bits (92), Expect = 0.006
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 12/101 (11%)
Query: 303 RKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKI 362
++E E K+++R+ E K K E E ++ KKEK KK K+ER K R +
Sbjct: 31 QRESERKKERRERE-------KRKREREKERKRERGKKEK---KKRKKRERGKERERKRK 80
Query: 363 EEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSE 403
E E+ RKE+ E E R R+ K + G K E
Sbjct: 81 ER--EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 61.2 bits (147), Expect = 2e-09
Identities = 31/144 (21%), Positives = 88/144 (61%), Gaps = 4/144 (2%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE 292
E++EK ++E+ W +++ + ++ +E+ ++R + + D R++ E+E+ +E
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR---EKEERMRE 377
Query: 293 AEKKAKAEAKRKEQEA-KEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
EK + E K +E+E +E++++ E + +++E+ + +++ + ++EK+ Q++ + +
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 352 ERQKLRNSCKIEEINEQIRKEKEE 375
+++KL K++E E+I +++E+
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEK 461
Score = 60.1 bits (144), Expect = 5e-09
Identities = 69/373 (18%), Positives = 156/373 (41%), Gaps = 38/373 (10%)
Query: 222 DSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRT----LVDNAYSCD 277
+ WR+ L E+EK K ++E+ W +++ + + +E+ ++R L +
Sbjct: 235 EMWRQEEELREQEK-KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALL 337
+ K+ +E++K +++ E+ + E K EQE K ++++ ++ ++E+++R+Q
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
Query: 338 AKKEKD---IQKKAIKKERQKLRNSCKI----------EEINEQIRKEKEEAEARMRQAS 384
+ +++ Q + ++++ +++R K+ E I E+ +K +EE E Q
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 385 KNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWE---VIANYMNIHSSSGVKR 441
K ++ K W + L P WE + I R
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRL----------PEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 442 TAKDVIGKAKSL--QKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPS-----ERFEGP 494
+++ G+ K + Q+ Q+D + ++ +E + Q + E+ E
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523
Query: 495 YTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKK 554
W EE+ E+ + T ++ EK+ E R ++ M+ +E++ + K
Sbjct: 524 REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 583
Query: 555 AAQEQVLNASRAK 567
QE+ + K
Sbjct: 584 QEQEEKMREQEEK 596
Score = 54.3 bits (129), Expect = 3e-07
Identities = 71/374 (18%), Positives = 153/374 (40%), Gaps = 34/374 (9%)
Query: 224 WREFSYLDEEEKE------KAECRDERRWIEKQNRATRAQRKKEE--MNRIRTLVDNAYS 275
WR+ L E+EK+ K ++ER W + + + +R +E+ M +
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 276 CDPRIKKFKEEEKAKKEAEKKA-KAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQ 334
R KK +EEE+ +E E+K K E EQE KE Q+Q E E+E+ + +++
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
Query: 335 ALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE----------EAEARMRQAS 384
+ ++EK ++ + + +K+ K+ E +Q+ +++E + E RM +
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513
Query: 385 KNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAK 444
+ + K W +++ K T + E + + R +
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 445 DVI-----------GKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEG 493
+++ K + ++ Q++ + ++ +++E + Q + E+ E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 494 PYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAK 553
+ +E+K+ EQ K E+ + E + G+ +K M+ +E ++ + K
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMR--EQEEKMREQEEKMQGQEEK--MREQEEKMQGQEEK 689
Query: 554 KAAQEQVLNASRAK 567
QE+ + K
Sbjct: 690 MREQEEKMRGQEEK 703
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/188 (22%), Positives = 91/188 (48%), Gaps = 17/188 (9%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRK--KEEMNRIRTLVDNAYSCDPRIKKFKEEE- 287
+E +K+ AE +++ R E + + K K ++ R + L+ + + + +++EE
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 288 ------KAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKE 341
K +K+ EK + E + +EQE K ++++ ++ ++E+E+R+Q +KE
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ----EKE 298
Query: 342 KDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE----EAEARMRQASKNTEKSTGGGGNG 397
QKK ++E Q K+ E E++R+++E + E Q + E+
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 398 SKNWSEDD 405
+ W +D+
Sbjct: 359 ERMWEQDE 366
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/202 (23%), Positives = 97/202 (48%), Gaps = 18/202 (8%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRI---RTLVDNAY 274
W + RE E+EK+ + ++ R E+ + R++EEM R +
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 275 SCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEK-QRQAEL-----EAARLAKEK-- 326
+ K +++EEK +++ EK + E K EQE ++K Q Q E+ E + +EK
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 327 -EEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASK 385
+EE++R+Q +++ Q++ ++ + +K+R + E++ Q K +E+ E Q K
Sbjct: 650 EQEEKMREQ----EEKMREQEEKMQGQEEKMRE--QEEKMQGQEEKMREQEEKMRGQEEK 703
Query: 386 NTEKSTGGGGNGSKNWSEDDLQ 407
+ G K W +++++
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMR 725
Score = 52.4 bits (124), Expect = 1e-06
Identities = 36/147 (24%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 243 ERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAK 302
E W +Q R Q KK IR + + + R+++ +E K +++ EK + E +
Sbjct: 234 EEMW--RQEEELREQEKK-----IRKQEEKMWRQEERLRE--QEGKMREQEEKMRRQEKR 284
Query: 303 RKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKI 362
+EQE + ++++ EL + +E+EE+ Q+ + ++E+ ++++ K RQ+ R +
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 363 EEINEQIRKEKEEAEARMRQASKNTEK 389
+++ EQ +K +++ E Q + EK
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREK 371
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/162 (20%), Positives = 83/162 (51%), Gaps = 16/162 (9%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
+E++EK ++E+ W +++ + ++ E+ ++ + + +++EEK ++
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643
Query: 292 EAEKKAKAEAKRKEQEAK------------EKQRQAELEAARLAKEKEEEEVRQQALLAK 339
+ EK + E K +EQE K EK R+ E ++ ++E+ +++ + +
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE---EKMQGQEEKMREQEEKMRGQ 700
Query: 340 KEKDI-QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARM 380
+EK Q++ + + +K+ ++ E E+IR +KE+ + R+
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 43.5 bits (101), Expect = 5e-04
Identities = 25/124 (20%), Positives = 66/124 (53%), Gaps = 2/124 (1%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
++EE++K + ++E W +++ + ++ E+ ++R + + +++ +EEK +
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG--QEEKMR 677
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
++ EK E K +EQE K + ++ ++ +EE++ Q + +KE+ I+ + K
Sbjct: 678 EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Query: 351 KERQ 354
+ +
Sbjct: 738 MQER 741
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/101 (20%), Positives = 51/101 (50%), Gaps = 3/101 (2%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
W + RE E++EK + ++E+ +++ + ++ +E+ ++R + + +
Sbjct: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 278 PRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELE 318
K + +EEK + E + K E + ++Q+ K ++R E E
Sbjct: 709 E--KMWGQEEKMWGQEEMREK-EERIRDQKEKMQERLPEHE 746
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/316 (22%), Positives = 135/316 (42%), Gaps = 50/316 (15%)
Query: 161 DPTFDN---SVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSF 217
DPT + S+PS+ D T E++ + + + + S++ D
Sbjct: 116 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND----- 170
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWI----EKQNRATRAQRKKEEMNRIRTLVDN- 272
WR+ +E+KEK E +E+ E Q + + ++ KE +++ +D
Sbjct: 171 ------WRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRK 224
Query: 273 -------AYSCDPRIKKFKEEEKA-----------KKEAEKKAKAEAKRKEQEAKEKQRQ 314
+ + + K K E KEAE + EA ++ +E + ++ +
Sbjct: 225 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 284
Query: 315 AELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
E E K+K++E + L KK+++ ++K +++E Q+ K EE + ++R+E+E
Sbjct: 285 TESEEFEKLKQKQQEAALELEEL-KKKREERRKVLEEEEQRR----KQEEADRKLREEEE 339
Query: 375 EAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLF-PAGTNSRWEVIANYMN- 432
+ R+ + E+ + ED L K F P G++ + E A ++N
Sbjct: 340 K-----RRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 394
Query: 433 -IHSSSGVKRTAKDVI 447
+ SSGVK T + I
Sbjct: 395 SVQKSSGVKSTHQAAI 410
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 11/152 (7%)
Query: 231 DEEEKE-----KAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
DEE K + E DE ++E+ A+R++ R++ ++ DP I
Sbjct: 70 DEEAKTTTTNTQVEGDDEAAFLERL-----ARREERRQKRLQEALERQKEFDPTITDASL 124
Query: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
+++ A+ E KE++++ +Q + E+E + ++ + A KKE D +
Sbjct: 125 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE-DKE 183
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAE 377
K+ ++E+ K + + + +E+I+K+KE E
Sbjct: 184 KEEEEEEKPKRGSIGENQIKDEKIKKDKEPKE 215
Score = 30.4 bits (67), Expect = 4.5
Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+EE+A +E ++A+ E R++QE + + + +EE + + E D
Sbjct: 27 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD- 85
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
+A ER R + + + E + ++KE
Sbjct: 86 -DEAAFLERLARREERRQKRLQEALERQKE 114
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/316 (22%), Positives = 135/316 (42%), Gaps = 50/316 (15%)
Query: 161 DPTFDN---SVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSF 217
DPT + S+PS+ D T E++ + + + + S++ D
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND----- 176
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWI----EKQNRATRAQRKKEEMNRIRTLVDN- 272
WR+ +E+KEK E +E+ E Q + + ++ KE +++ +D
Sbjct: 177 ------WRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRK 230
Query: 273 -------AYSCDPRIKKFKEEEKA-----------KKEAEKKAKAEAKRKEQEAKEKQRQ 314
+ + + K K E KEAE + EA ++ +E + ++ +
Sbjct: 231 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 290
Query: 315 AELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
E E K+K++E + L KK+++ ++K +++E Q+ K EE + ++R+E+E
Sbjct: 291 TESEEFEKLKQKQQEAALELEEL-KKKREERRKVLEEEEQRR----KQEEADRKLREEEE 345
Query: 375 EAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLF-PAGTNSRWEVIANYMN- 432
+ R+ + E+ + ED L K F P G++ + E A ++N
Sbjct: 346 K-----RRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNK 400
Query: 433 -IHSSSGVKRTAKDVI 447
+ SSGVK T + I
Sbjct: 401 SVQKSSGVKSTHQAAI 416
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 11/152 (7%)
Query: 231 DEEEKE-----KAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
DEE K + E DE ++E+ A+R++ R++ ++ DP I
Sbjct: 76 DEEAKTTTTNTQVEGDDEAAFLERL-----ARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
+++ A+ E KE++++ +Q + E+E + ++ + A KKE D +
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE-DKE 189
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAE 377
K+ ++E+ K + + + +E+I+K+KE E
Sbjct: 190 KEEEEEEKPKRGSIGENQIKDEKIKKDKEPKE 221
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/76 (22%), Positives = 39/76 (51%)
Query: 302 KRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCK 361
+R+ + ++K+ + LEA R+A ++ +++ + A ++ ++ K+E + L
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 362 IEEINEQIRKEKEEAE 377
E+N Q EEA+
Sbjct: 65 QVEVNAQNSVPDEEAK 80
Score = 30.8 bits (68), Expect = 3.5
Identities = 26/106 (24%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQE-AKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
++ E+ + EAE+ A E+E A+E++R+A E RL +++EEE + Q + + E
Sbjct: 13 QKREEMRLEAERIAYQRNDDDEEEAARERRRRARQE--RLRQKQEEESLGQ--VTDQVEV 68
Query: 343 DIQKKAIKKERQKLRNSCKIE-----EINEQIRKEKEEAEARMRQA 383
+ Q +E + + ++E E++ + +E + R+++A
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEA 114
Score = 30.4 bits (67), Expect = 4.5
Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
+EE+A +E ++A+ E R++QE + + + +EE + + E D
Sbjct: 33 DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD- 91
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKE 374
+A ER R + + + E + ++KE
Sbjct: 92 -DEAAFLERLARREERRQKRLQEALERQKE 120
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 60.8 bits (146), Expect = 3e-09
Identities = 70/302 (23%), Positives = 135/302 (44%), Gaps = 63/302 (20%)
Query: 229 YLDEE----EKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
Y++E E+EK E ++W +K RA +E+N R +D + +
Sbjct: 195 YIEERLHTLEEEKEELAQYQKW-DKMRRALEYTIYNQELNETRAKLDE-------LSAKR 246
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE------EEVRQQALLA 338
E K + A+ +A+ K ++ + + R+ + + + + +EKE+ E+++Q+ L
Sbjct: 247 ETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLE 306
Query: 339 KKEKDIQ---------KKAIKKERQKLRNSCKIEEINEQIR---------KEKEEAE-AR 379
K KD+Q +K + KERQKL KIEE +++ KEKEE AR
Sbjct: 307 LKAKDLQDELAGNSEQRKRLLKERQKLLE--KIEEKQKELAETEPKFNSVKEKEERGIAR 364
Query: 380 MRQASKNTEKSTGGGGNGSK--------NWSEDDLQLLIKAVNLFPAGTNSRWEVIANYM 431
+ QA++ G GS+ W + +L+ L +A+N + + ++ A +
Sbjct: 365 LAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAIN------DKKRQIAAIHK 418
Query: 432 NIHSSSGVK--------RTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQAD 483
++ + K + +D+ +++LD + NKK D+ + E + + +
Sbjct: 419 DLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKK--DELQSERNYLWREE 476
Query: 484 NA 485
NA
Sbjct: 477 NA 478
Score = 40.0 bits (92), Expect = 0.006
Identities = 58/272 (21%), Positives = 112/272 (41%), Gaps = 40/272 (14%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E +K+ + +E +E + + + N I L++ + + +KFK +
Sbjct: 677 ELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSIL 736
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAE-LEAARLAKEKEEEEVRQQA---LLAKKEKDIQKK 347
K K + ++ E+ KQR + LEA+ A E E ++ + LL++ + QK+
Sbjct: 737 SEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKR 796
Query: 348 A----------IKKERQKLRNSCKIEEI--------NEQIRKEKEEAEARMRQASKNTEK 389
++ RQ L K+E I NE +RK ++ E + N +
Sbjct: 797 VDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQEL-----NELR 851
Query: 390 STGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGK 449
T GG + SE ++A+N T +R E + N ++ + +G+K K +
Sbjct: 852 ETEGGTVLTATTSE------LEAINKRVKDTMARSEDLDNSID-KTEAGIKELQKSM--- 901
Query: 450 AKSLQKLDPHQKDDIN--KKAFDKFKKEHGVV 479
+ + ++ D IN K +K G++
Sbjct: 902 -ERWKNMEKEHMDAINHDTKELEKMTNRQGML 932
Score = 31.2 bits (69), Expect = 2.7
Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 18/102 (17%)
Query: 260 KEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEA-------------EKKAKA-EAKRKE 305
K+E+ + +++ I K E+ +A KE E KA+ E RK
Sbjct: 396 KKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKY 455
Query: 306 QEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKK 347
E K K+ + + E L + EE QQAL AK+E D++KK
Sbjct: 456 YEVKNKKDELQSERNYLWR---EENAEQQALAAKRE-DLEKK 493
Score = 30.8 bits (68), Expect = 3.5
Identities = 63/321 (19%), Positives = 127/321 (39%), Gaps = 28/321 (8%)
Query: 259 KKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAEL- 317
K+ ++N++ T D+ R+K +E + E+K ++ + KE E K ++ L
Sbjct: 140 KQGKINQMATAPDSQ-----RLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLK 194
Query: 318 --EAARLAKEKEEEEVRQQALLAKK----EKDIQKKAIKKERQKLRNSCKIEEINEQIRK 371
E E+E+EE+ Q K E I + + + R KL E + + +
Sbjct: 195 YIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSR 254
Query: 372 EKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYM 431
+ +A+ R ++ E+ E+ QL + T + E+ A +
Sbjct: 255 QLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRT--KLELKAKDL 312
Query: 432 NIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDIN---KKAFDKFKKEHGVVPQA---DNA 485
+ ++ + + + K L+K++ QK+ K K K+E G+ A
Sbjct: 313 QDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQER 372
Query: 486 TPSERFEGPYTDFT------PWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDC 539
T +G + FT W +E K L+QA+ + + + + K
Sbjct: 373 TDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKN-- 430
Query: 540 MKRYKELVEMVKAKKAAQEQV 560
+++Y +L + + KA E++
Sbjct: 431 LEQYNKLDQDLNEVKARVEEL 451
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/187 (24%), Positives = 90/187 (48%), Gaps = 20/187 (10%)
Query: 232 EEEKEKAECRDERRWIEKQN----RATRAQRKKEEMNRIRTLVDNAYSCD-PRIKKFKEE 286
E EK + E R+ R EK+N R + R++E T + D R ++ K E
Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE 239
Query: 287 EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQK 346
+ +K+AE++ +E + + + +E++R + + R KE+E + R++ +++++ ++
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 347 KAIK---KERQKLRNSCKIEEINEQIR-----------KEKEEAEARMRQASKNTEKSTG 392
K + +ER++ RN K E E+ R +EKE R RQ + E++
Sbjct: 300 KRERQRERERERERNR-KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 393 GGGNGSK 399
G G +
Sbjct: 359 TGREGRR 365
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/167 (24%), Positives = 84/167 (50%), Gaps = 10/167 (5%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
D E + K E + ER ++NR +R++E R R R +K K + +
Sbjct: 294 DRETERKRERQRERERERERNRKRERERERER-ERERQRETERDREKERERKRKRQTEMD 352
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVR----QQALLAKKEKDIQK 346
+E ++ E +R+ + +E++R+ + ++AR +E+E + R ++ +K++D Q+
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 347 KAIK-KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTG 392
+ K +ER+K R S E + +E+E+ + R R + T++ G
Sbjct: 413 ETEKQREREKDRES----ERGRERGREREKQKGRERDRERQTDRQAG 455
Score = 55.5 bits (132), Expect = 1e-07
Identities = 41/162 (25%), Positives = 79/162 (48%), Gaps = 5/162 (3%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEE---K 288
+ ++E+ R R EKQ RA ++ E ++ R + R +K +E + K
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 289 AKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKA 348
++ E+ + E KR+ Q +E++R+ + R +E+E E RQ+ +EK+ ++K
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRER-ERERERERERQRETERDREKERERKR 345
Query: 349 IKK-ERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ E + RN E Q +E+E R RQ+++ E+
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Score = 55.1 bits (131), Expect = 2e-07
Identities = 35/165 (21%), Positives = 82/165 (49%), Gaps = 10/165 (6%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIR-------TLVDNAYSCDPRIKKFK 284
E+E+E+ R+ +R E+ + R + K + R R ++ +S R ++ +
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDI 344
E + + E +++ E R+ + +E+++QAE E A E+E E +++ +++D
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERER---ASERETERDKERERERDRDRDR 272
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
++ ++ERQ R + E + + +++E R R+ +N ++
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/177 (23%), Positives = 87/177 (49%), Gaps = 24/177 (13%)
Query: 223 SWREFSYLDEEEKEKAECRD-ERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIK 281
S RE E E+E+ RD +RR E++ + R ++++ E +R +
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE------------R 299
Query: 282 KFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKE 341
K + + + ++E E+ K E +R+ + +E+QR+ E + +EKE E R++ +E
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERD-----REKERERKRKRQTEMDRE 354
Query: 342 KDIQ-----KKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGG 393
++ Q ++ ++ER++ R + + E+ +E++ R ++ + TEK G
Sbjct: 355 RNRQTGREGRRQAERERERERERDR-QSAREREERERDRDRDRQKERERQTEKDRDG 410
Score = 54.7 bits (130), Expect = 2e-07
Identities = 41/166 (24%), Positives = 79/166 (47%), Gaps = 5/166 (3%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
++E+E+ R +R E+ R + ++ E R R R ++ + + + ++
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLA---KEKEEEEVRQQAL-LAKKEKDIQKK 347
+ EK+ + + KR+ + +E+ RQ E R A +E+E E RQ A ++E+D +
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 348 AIK-KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTG 392
K +ERQ ++ E +Q +EK+ R R+ + EK G
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Score = 50.1 bits (118), Expect = 6e-06
Identities = 37/164 (22%), Positives = 85/164 (51%), Gaps = 9/164 (5%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+ +++ E R E+R E++ R +R++++ +R R + + R ++ + E +
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKR----DRHRERQRDREKERERQTD 110
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+E +++ + E R+++ +E +R+ E R + E E ++ A +KE++ Q +
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDA---EKERERQTDR-E 166
Query: 351 KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGG 394
++RQ RN K E E+ R+E+ E E + + +K ++ + G
Sbjct: 167 RQRQTERNRQKERE-REKNRQERRERERQREKENKTEDRHSERG 209
Score = 49.7 bits (117), Expect = 7e-06
Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE + E K E R E+ K++R QR +E+ +T + R ++ +
Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE-------RDRQRE 118
Query: 285 EEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEA-ARLAKEKEEEEVRQQALLAKKEKD 343
+E +KE E++ + E +R + QR+ E + A +E++ + RQ+ ++K+
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+++ ++ER++ + E E E+ R R+ TE+
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224
Score = 49.3 bits (116), Expect = 9e-06
Identities = 39/168 (23%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
E E+ + D +R E+Q A + + ++ + R R N R K +E + ++
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 292 EAEKKAKAEAKRKEQ-EAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+ EK+ K E + E+ +E++R+ E E R ++ + E RQ+ ++EK +++
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETER-KRQTDRERDRQRKTEREREKQAERERAS 252
Query: 351 -------KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKST 391
KER++ R+ + ++ +KE+E R RQ ++ T
Sbjct: 253 ERETERDKERERERDR---DRDRDRRQKERERQTDRKRQRRTERDRET 297
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/167 (22%), Positives = 76/167 (45%), Gaps = 13/167 (7%)
Query: 232 EEEKEKAECRDERRWIEKQ-----NRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEE 286
+ EKE+ ++ R E++ +R T QR++E R R R ++ + E
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERE---RQRDAEKERERQTDRERQRQTE 172
Query: 287 EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAK----KEK 342
+KE E++ + +R+ + +EK+ + E + +E+E E + K +E+
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
D Q+K ++ER+K + E + KE+E R R + ++
Sbjct: 233 DRQRKT-EREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 31/168 (18%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
D+ E+ + + R+ RR EK+ RK+E R ++ K
Sbjct: 52 DDRERNRQKERERRR--EKRQTERETDRKRE-----------------RRREKDRHRKRD 92
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEV--------RQQALLAKKEK 342
+ E++ E +R+ Q +E+ RQ E E R +KE E R + ++E+
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNR---QKERERETEREGERGRDRQTDGQRER 149
Query: 343 DIQKKAIK-KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+ Q+ A K +ERQ R + E N Q +E+E+ R+ + EK
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
+ ++EK R + R E + R + ++ + R R +A R + + + ++
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
+K+ + E R+E+ +E+QR+ E + E+ E R++ + E+ K+ +
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER---KRQTDR 230
Query: 352 ERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
ER + R + E + + E+E A R + K E+
Sbjct: 231 ERDRQRKT----EREREKQAERERASERETERDKERER 264
Score = 43.5 bits (101), Expect = 5e-04
Identities = 34/165 (20%), Positives = 76/165 (46%), Gaps = 13/165 (7%)
Query: 232 EEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKK 291
+ EKE+ D R +++ R + ++ E R + D + +E E+ ++
Sbjct: 100 DREKERERQTDRERDRQREKERNRQKERERETER-----EGERGRDRQTDGQRERER-QR 153
Query: 292 EAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE-EEVRQQALLAKKEKDIQKKAIK 350
+AEK+ + + R+ Q E+ RQ E E + +E+ E E R++ + + + +
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 351 KER------QKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+ER ++ R + + + + +E+E+ R R + + TE+
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Score = 38.5 bits (88), Expect = 0.017
Identities = 22/106 (20%), Positives = 56/106 (52%), Gaps = 4/106 (3%)
Query: 288 KAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKK 347
+A K+A+ + ++KE+E + ++RQ E E R + + E++ ++ ++ + ++K
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 348 AIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGG 393
+++ + R+ + +E N Q +E+E R+ + ++ T G
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETE----REGERGRDRQTDG 145
Score = 37.4 bits (85), Expect = 0.037
Identities = 19/108 (17%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
F +E+ ++ K+ + +++R + E R ++++ E + ++EK
Sbjct: 26 FSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 343 DIQKKAIK-KERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
D +K + +ERQ+ R + + + + +++E+ R ++ + TE+
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER 133
Score = 36.2 bits (82), Expect = 0.083
Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 20/135 (14%)
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEK----------QRQAELEAARLAKEKEEEEVRQ 333
+++E+ ++ +++ + E RK + +EK +RQ + E KE+E + R+
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE-----KERERQTDRE 112
Query: 334 QALLAKKEKDIQKKAIKK-----ERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTE 388
+ +KE++ QK+ ++ ER + R + E Q EKE R+ + TE
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 389 KSTGGGGNGSKNWSE 403
++ KN E
Sbjct: 173 RNRQKEREREKNRQE 187
Score = 35.4 bits (80), Expect = 0.14
Identities = 22/105 (20%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 220 NFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279
N + RE E E+E+ RD + E++ R R +++ +T D +
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Query: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAK 324
++ +E+++ + ++ + K+K +E ++++RQ + +A R K
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRE-RDRERQTDRQAGRQRK 459
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.7 bits (143), Expect = 7e-09
Identities = 44/171 (25%), Positives = 90/171 (52%), Gaps = 16/171 (9%)
Query: 230 LDEEEKEKAECRD-----ERRWIEKQNRATRAQRKKE----EMNRIRTLVDNAYSCDPRI 280
LD+EE+ E + +RRW K+ A R + KE +++ + + + + +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRW-RKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL 2234
Query: 281 KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQ--RQAELEAARLAKEKEEEEVRQQALLA 338
+ +++E E E++ + E +R+E+E +E++ R+ E E EKEEEE +++
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 339 KKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
KKE+ +K+ + +E++++ + EE E + E+EE E+ + + EK
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMS----EEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 56.6 bits (135), Expect = 6e-08
Identities = 54/174 (31%), Positives = 88/174 (50%), Gaps = 30/174 (17%)
Query: 191 RWSNKKNVPKLGD-----MNSSFEDVDIFYSFWYNFDSW----REFSYLDEEEKEKAECR 241
RW +K K GD +S ++V+ F +S + L EE+E+ E
Sbjct: 2196 RWRKRKEA-KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254
Query: 242 DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEA 301
+ER E++ R +RK+EE + +++K +EEEK KK+ EKK K E
Sbjct: 2255 EERE--EEEVREEEEERKEEEEGE-----------EKQVEK-EEEEKKKKKKEKK-KEEV 2299
Query: 302 KRKEQEAKEKQR-QAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQ 354
+ KE+ +EK+ +E E L+ E+EEEE + ++E D +K+ +KKE+Q
Sbjct: 2300 QEKEEVFEEKEEIMSEEETESLSDEEEEEE----SCSLEEEVDREKEILKKEKQ 2349
Score = 47.0 bits (110), Expect = 5e-05
Identities = 52/230 (22%), Positives = 99/230 (43%), Gaps = 39/230 (16%)
Query: 184 PVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDE 243
P E+N W K+ +L ++ E++ SW+E +E +E+ + +E
Sbjct: 1701 PQREQNLDWQEKELAQELEELEWDMEEL-----------SWKE----EELNQEEGKLVEE 1745
Query: 244 RRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKE----------- 292
++ + ++ A QR+K + + + K + +EK +E
Sbjct: 1746 KKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Query: 293 AEKKAKAEAKRK------EQEAKEK-----QRQAELEAARLAKEKEEEEVRQQALLAKKE 341
EKK K KR+ E+ K K ++ E LA+EKE+ R++ LL KE
Sbjct: 1806 IEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKE 1865
Query: 342 K-DIQKKAIKKERQKLRNSCKI-EEINEQIRKEKEEAEARMRQASKNTEK 389
+ KK + + + KL KI ++ E++ +EKE + + ++ +K
Sbjct: 1866 RLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKK 1915
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/374 (21%), Positives = 149/374 (39%), Gaps = 60/374 (16%)
Query: 56 KKELSEESEDEELQLEEFPML---------------KTLDPKDWKN--QDHYAVLGLGHV 98
K+E+++E D ++EE L +T +DWK + V G
Sbjct: 1417 KREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRK 1476
Query: 99 RYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFN 158
+KA + + + L +K AGE + + EML + K+ +
Sbjct: 1477 SWKAWKEEWEKR-----LLQEEEKLHQAGEKLSPEE-----------EMLQED-KKLKWE 1519
Query: 159 SVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFW 218
++N + SKS+ + E + E SR +K + E+ W
Sbjct: 1520 EWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK-----W 1574
Query: 219 YNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDP 278
R + ++E+ ++E + +++ + + +RK + T D +
Sbjct: 1575 ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634
Query: 279 RIKKFKEE------EKAKKEAEK---KAKAEAKRKEQEAKEKQRQAE-----LEAARLAK 324
KEE EK +EAEK K K AK+ E+ A+E+++ A+ E +
Sbjct: 1635 GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILA 1694
Query: 325 EKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEIN-------EQIRKEKEEAE 377
+K EE +++ L +EK++ ++ + E S K EE+N E+ +K EE E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Query: 378 ARMRQASKNTEKST 391
A Q K +E+ T
Sbjct: 1755 ALAWQREKLSEEET 1768
Score = 40.8 bits (94), Expect = 0.003
Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Query: 231 DEEEKEKAECRDERRWIEKQ----NRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEE 286
D EK +DE++ KQ N+ R K+E+M + + +S + EE
Sbjct: 2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHS---EVILDDEE 2180
Query: 287 EKAKKEAEKKAKAEAK-RKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQ 345
E +E E + + RK +EAK + E ++++ + + EE ++ E + Q
Sbjct: 2181 EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQ 2240
Query: 346 KKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDD 405
+ +E ++ + EE E++R+E+EE + K EK K +++
Sbjct: 2241 ESLSSEEEEEREEEEEREE--EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Query: 406 LQ 407
+Q
Sbjct: 2299 VQ 2300
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 18/135 (13%)
Query: 231 DEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
+EEE+E+ E R+E +++ Q +KEE + + + +K KEE + K
Sbjct: 2253 EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK----------KKEKKKEEVQEK 2302
Query: 291 KEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIK 350
+E ++ K E +E+ + E E+ L EEEV ++ + KKEK Q K +
Sbjct: 2303 EEVFEE-KEEIMSEEETESLSDEEEEEESCSL-----EEEVDREKEILKKEK--QFKLQE 2354
Query: 351 KERQKLRNSCKIEEI 365
+ R+ LR ++ I
Sbjct: 2355 QRRKSLRGRERVLSI 2369
Score = 37.7 bits (86), Expect = 0.028
Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 16/161 (9%)
Query: 233 EEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVD--NAYSCDPRIKKFKEEEKAK 290
+EKEK R E K+ R K+++ +++ + N K +E+E
Sbjct: 1848 QEKEKLAQRKENLLYNKE----RLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVI 1903
Query: 291 KEAEKKAKAEAK--RKEQEAKEKQRQAELEAARLAKEKE----EEEVRQQALLAKKEKDI 344
K+ EK A+ E K + E +KQ + E +LA EK ++ +R + +AK+EK +
Sbjct: 1904 KKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKAL 1963
Query: 345 QKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASK 385
+ + +K+R + E E + K + +R R+ ++
Sbjct: 1964 NLEMKRLAEEKMR----LVEGKETLSKGETPETSRQRKMTQ 2000
Score = 33.5 bits (75), Expect = 0.54
Identities = 35/165 (21%), Positives = 88/165 (53%), Gaps = 9/165 (5%)
Query: 230 LDEEEKEKAECRDE--RRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKK---FK 284
L +E ++ A+ R + ++W + + +K ++ ++ ++ P+ ++ ++
Sbjct: 1651 LSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ 1710
Query: 285 EEEKAKKEAEKK-AKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
E+E A++ E + E KE+E +++ + E +LA+E+E +++ L ++ K
Sbjct: 1711 EKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKL 1770
Query: 344 IQKKAIK-KERQKL-RNSCKIEEINEQI-RKEKEEAEARMRQASK 385
Q++ + +E++KL ++ K+ E E++ RK ++ E +M+ A K
Sbjct: 1771 AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK 1815
Score = 31.2 bits (69), Expect = 2.7
Identities = 27/115 (23%), Positives = 55/115 (47%), Gaps = 11/115 (9%)
Query: 287 EKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE--EEVRQQALLAKKEKDI 344
++ K+ EKK ++ ++ ++A +K+R+ + KE+ + EEV + A L +K
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ 1444
Query: 345 QKKAIKKERQKLRNSCK-----IEEINEQIRKE----KEEAEARMRQASKNTEKS 390
+ K + ER K ++++ + RK KEE E R+ Q + ++
Sbjct: 1445 EGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQA 1499
Score = 30.0 bits (66), Expect = 5.9
Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKD 343
+EEE+A+K+A E + K+ ++ LE + KE + ++ K K
Sbjct: 1345 REEEQAQKKARDMLGLE--ETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQ 1402
Query: 344 IQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+KA++KER K+ +I ++ KE+ + + + + EK
Sbjct: 1403 -GRKAVQKER-------KVGKIKREMTKEERDMSEEVEEMATLEEK 1440
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 59.7 bits (143), Expect = 7e-09
Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 7/146 (4%)
Query: 232 EEEKEKAECRDERRWIEKQN-RATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAK 290
E+E+E+ + RD +R E++ R T QR+++ + D D ++ +E ++ +
Sbjct: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
Query: 291 KEAEKKAKAEAKRKEQEA---KEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKK 347
+ K + K+ E+E +E+QRQ E E R + K E + +Q ++E+ KK
Sbjct: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREER---KK 169
Query: 348 AIKKERQKLRNSCKIEEINEQIRKEK 373
KKER+K R K EE + +K K
Sbjct: 170 ERKKERKKERKEKKKEEKRREDKKRK 195
Score = 47.8 bits (112), Expect = 3e-05
Identities = 37/169 (21%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 225 REFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFK 284
RE E E+E+ R+ E++NR + R +E D + ++ K
Sbjct: 9 RETDRGKETERERDRQRERENQTERENRHRQRDRHRER--------DRQTDREKERERQK 60
Query: 285 EEEKAK-KEAEKKAKAEAKRKEQEAKEKQRQAELEAAR---LAKEKEEEEVRQQALLAKK 340
E ++ + +E E + + E +R+ Q +E++RQ + E + +++E + R++ +
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 341 EKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
E+D Q + +++R++ R + E Q +++E R R A + K
Sbjct: 121 ERDKQTER-ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK 168
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Query: 279 RIKKFKEEEKAKKEAEKKAKAEAKRK---EQEAKEKQRQAELEAARLA-KEKEEEEVRQQ 334
R ++ K E KE E++ + +R+ E+E + +QR E R +EKE E +++
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 335 ALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGG 394
++E++ +++ ERQ+ R + + ++K+ R R+ +N E++ GG
Sbjct: 63 DRQRQRERETERET---ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 395 GNGSK 399
K
Sbjct: 120 RERDK 124
Score = 39.7 bits (91), Expect = 0.007
Identities = 19/100 (19%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Query: 290 KKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAI 349
+++ E+K + + ++ + +++QR+ E + R + ++ + R++ +EK+ ++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERER--- 58
Query: 350 KKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
+KER + R + E + ++E++ R RQ + +K
Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98
Score = 31.2 bits (69), Expect = 2.7
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 20/82 (24%)
Query: 225 REFSYLDEEEKEKAECRDERRWI--EKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKK 282
RE + E+E+ R+ +R E+Q A R +RKKE KK
Sbjct: 132 RERERQRQRERERQRQRERKRETDRERQRWAEREERKKER------------------KK 173
Query: 283 FKEEEKAKKEAEKKAKAEAKRK 304
+++E+ +K+ E+K + + KRK
Sbjct: 174 ERKKERKEKKKEEKRREDKKRK 195
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/178 (24%), Positives = 98/178 (55%), Gaps = 27/178 (15%)
Query: 222 DSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIK 281
+ WR+ +E+ +E+ E R E+ W +++ + +E+ +IR + + + +I+
Sbjct: 389 EMWRQ----EEKIREQEEKRQEKMWRQEK-------KMREQDEKIREQEEEMWRQEEKIR 437
Query: 282 KFKE-----EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQAL 336
+ +E EEK ++ EK + E K +EQE K ++++ +++ E+EE+ RQ+ L
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ------EQEEKTWRQEKL 491
Query: 337 LAKKEK--DIQKKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQASKNTEK 389
L ++EK + ++K ++E + K++E E++++++E E E R+ Q + ++
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/167 (24%), Positives = 82/167 (49%), Gaps = 18/167 (10%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMN-RIRTLVDNAYSCDPRIKK 282
WR+ + E+E++ C E + E++ + R + K E +IR D K
Sbjct: 300 WRQEEKIQEQEEKM--CEQELKIREQEEKMWRQEEKMHEQEEKIREQED---------KM 348
Query: 283 FKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEK 342
+++EEK +++ EK + E K QE K +++ +++ E+EEE RQ+ + ++E+
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ------EQEEEMWRQEEKIREQEE 402
Query: 343 DIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEK 389
Q+K ++E++ KI E E++ +++E+ EK
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Score = 55.8 bits (133), Expect = 1e-07
Identities = 43/182 (23%), Positives = 95/182 (52%), Gaps = 22/182 (12%)
Query: 227 FSYLDEEEKEK-------------AECRDERRWIEKQNRATRAQRK-KEEMNRIRTLVDN 272
++ L+++++EK C E + E++ + R + K E+ +IR D
Sbjct: 288 WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 273 AYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVR 332
+ + +I+ ++EEK +++ EK + E K +EQ+ K ++++ E+ K +E+EE R
Sbjct: 348 MWRQEEKIR--EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-EKIREQEEKR 404
Query: 333 QQAL--LAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKE---EAEARMRQASKNT 387
Q+ + KK ++ +K ++E + R KI E+ E ++ ++E E E +M++ +
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 388 EK 389
++
Sbjct: 465 QE 466
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/200 (21%), Positives = 98/200 (49%), Gaps = 28/200 (14%)
Query: 224 WREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKF 283
WR+ + E+E EK ++++ W +++ + +E+ +IR + + + +I++
Sbjct: 328 WRQEEKMHEQE-EKIREQEDKMWRQEE-------KIREQEEKIREQEEKMWRQEEKIRE- 378
Query: 284 KEEEKAKKEAEKKAKAEAKRKEQEAKE-----KQRQAELEAARLAKEKEEEEVRQQALLA 338
++EK +++ E+ + E K +EQE K +Q + E +E+EEE RQ+ +
Sbjct: 379 -QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 339 KKE----------KDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEA---EARMRQASK 385
+ E +++++K ++E + KI+ E+I++++E+ E ++Q K
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 386 NTEKSTGGGGNGSKNWSEDD 405
E+ K W +++
Sbjct: 498 IWEQEEKMWRQEEKMWEQEE 517
Score = 49.3 bits (116), Expect = 9e-06
Identities = 79/391 (20%), Positives = 169/391 (43%), Gaps = 62/391 (15%)
Query: 36 EAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGL 95
EA+++ R R + + E +D EESED + E + P D +D G+
Sbjct: 70 EAYLENRKRRGTKRWDEDDDL----EESEDSKQCKESLKRVTFTLPDDEAIED----AGV 121
Query: 96 GHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRR 155
HV K ++K++ K KR+ K + +Y + ++ P R
Sbjct: 122 SHV--KKNSDEVKSSFK---------KRQE-----KMNEKNY---TFRKRVVIKKPWLRL 162
Query: 156 AFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFY 215
+ +NS+ ++ D+ + T + + + +++ P L ++ D ++
Sbjct: 163 GEVTAQKRPENSLLEETLHFDHAVRMGTYI----EKLTKERDAPSLELYRNTITDEELKE 218
Query: 216 SFWYNFDSWREFSYLDEEEKE-KAECRDERRWIEK-------QNRATRAQRKKEEMNRIR 267
N + + ++ E+ E + +D +R +E+ Q A R +E+ +
Sbjct: 219 K---NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 268 TLVD---------NAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELE 318
+ N + K +++EEK +++ EK + E K +EQE K +++ ++
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 319 AARLAKEKEEEEVRQQA-LLAKKEKDI--QKKAIKKERQKL-RNSCKIEEINEQIRKEKE 374
++EE++R+Q + ++E+ I Q++ I+++ +K+ R KI E +E+I++++E
Sbjct: 336 -------EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 375 EAEARMRQASKNTEKSTGGGGNGSKNWSEDD 405
E + + + EK K E D
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/178 (21%), Positives = 86/178 (48%), Gaps = 9/178 (5%)
Query: 218 WYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCD 277
W + RE + ++++EK +E+ E++ + ++ + + +I+ + + +
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 278 PRIKK----FKEEEKAKKEAEKKAKAEAKRKEQEAK-----EKQRQAELEAARLAKEKEE 328
+K+ +++EEK ++ EK + E K +EQE K EK R+ E+ + ++ +E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 329 EEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKN 386
+EVR Q L + K QK + + S ++ + ++ E + EA+ Q ++
Sbjct: 550 QEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,865,361
Number of Sequences: 37866
Number of extensions: 1070626
Number of successful extensions: 29008
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 727
Number of HSP's successfully gapped in prelim test: 1124
Number of HSP's that attempted gapping in prelim test: 7625
Number of HSP's gapped (non-prelim): 9932
length of query: 568
length of database: 18,247,518
effective HSP length: 108
effective length of query: 460
effective length of database: 14,157,990
effective search space: 6512675400
effective search space used: 6512675400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.