Search of human proteins with 193083129

Search of human proteins with 193083129

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193083129 MAP/microtubule affinity-regulating kinase 3
isoform d [Homo sapiens]
         (713 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...  1420   0.0  
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...  1410   0.0  
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor...  1400   0.0  
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor...  1397   0.0  
gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ...  1011   0.0  
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...   910   0.0  
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...   904   0.0  
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...   902   0.0  
gi|193083131 MAP/microtubule affinity-regulating kinase 3 isofor...   889   0.0  
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor...   880   0.0  
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform...   865   0.0  
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s...   797   0.0  
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]        381   e-105
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                         355   1e-97
gi|116256471 SNF1-like kinase [Homo sapiens]                          352   7e-97
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]    289   7e-78
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]               288   1e-77
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]              283   5e-76
gi|156105707 SNF related kinase [Homo sapiens]                        268   1e-71
gi|156105705 SNF related kinase [Homo sapiens]                        268   1e-71
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun...   266   6e-71
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub...   263   5e-70
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]               262   9e-70
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]           256   4e-68
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]       255   9e-68
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub...   253   6e-67
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa...   222   8e-58
gi|14042947 testis-specific serine kinase 1 [Homo sapiens]            189   1e-47
gi|16418343 testis-specific serine kinase 3 [Homo sapiens]            188   2e-47
gi|194294513 testis-specific serine kinase 2 [Homo sapiens]           184   2e-46

>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score = 1420 bits (3677), Expect = 0.0
 Identities = 713/713 (100%), Positives = 713/713 (100%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
Sbjct: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
Sbjct: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ
Sbjct: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT
Sbjct: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360

Query: 361 YLLLGRKSSEVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRS 420
           YLLLGRKSSEVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRS
Sbjct: 361 YLLLGRKSSEVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRS 420

Query: 421 QTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSN 480
           QTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSN
Sbjct: 421 QTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSN 480

Query: 481 TASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFP 540
           TASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFP
Sbjct: 481 TASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFP 540

Query: 541 RGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSR 600
           RGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSR
Sbjct: 541 RGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSR 600

Query: 601 NVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFC 660
           NVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFC
Sbjct: 601 NVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFC 660

Query: 661 VHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 713
           VHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 661 VHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 713


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score = 1410 bits (3650), Expect = 0.0
 Identities = 713/729 (97%), Positives = 713/729 (97%), Gaps = 16/729 (2%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
Sbjct: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
Sbjct: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ
Sbjct: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT
Sbjct: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360

Query: 361 YLLLGRKSSE----------------VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 404
           YLLLGRKSSE                VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD
Sbjct: 361 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 420

Query: 405 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 464
           HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK
Sbjct: 421 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 480

Query: 465 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 524
           ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS
Sbjct: 481 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 540

Query: 525 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 584
           THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG
Sbjct: 541 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 600

Query: 585 STNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLD 644
           STNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLD
Sbjct: 601 STNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLD 660

Query: 645 ANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA 704
           ANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA
Sbjct: 661 ANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA 720

Query: 705 SKIANELKL 713
           SKIANELKL
Sbjct: 721 SKIANELKL 729


>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
           [Homo sapiens]
          Length = 744

 Score = 1400 bits (3624), Expect = 0.0
 Identities = 713/744 (95%), Positives = 713/744 (95%), Gaps = 31/744 (4%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
Sbjct: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
Sbjct: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ
Sbjct: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT
Sbjct: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360

Query: 361 YLLLGRKSSE----------------VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 404
           YLLLGRKSSE                VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD
Sbjct: 361 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 420

Query: 405 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 464
           HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK
Sbjct: 421 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 480

Query: 465 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 524
           ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS
Sbjct: 481 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 540

Query: 525 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 584
           THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG
Sbjct: 541 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 600

Query: 585 STNLFSKLTSKLTR---------------SRNVSAEQKDENKEAKPRSLRFTWSMKTTSS 629
           STNLFSKLTSKLTR               SRNVSAEQKDENKEAKPRSLRFTWSMKTTSS
Sbjct: 601 STNLFSKLTSKLTRRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRFTWSMKTTSS 660

Query: 630 MDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVR 689
           MDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVR
Sbjct: 661 MDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVR 720

Query: 690 FKRISGTSIAFKNIASKIANELKL 713
           FKRISGTSIAFKNIASKIANELKL
Sbjct: 721 FKRISGTSIAFKNIASKIANELKL 744


>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
           [Homo sapiens]
          Length = 753

 Score = 1397 bits (3615), Expect = 0.0
 Identities = 713/753 (94%), Positives = 713/753 (94%), Gaps = 40/753 (5%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
Sbjct: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
Sbjct: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ
Sbjct: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT
Sbjct: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360

Query: 361 YLLLGRKSSE----------------VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 404
           YLLLGRKSSE                VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD
Sbjct: 361 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSD 420

Query: 405 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 464
           HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK
Sbjct: 421 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 480

Query: 465 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 524
           ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS
Sbjct: 481 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 540

Query: 525 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 584
           THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG
Sbjct: 541 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 600

Query: 585 STNLFSKLTSKLTR------------------------SRNVSAEQKDENKEAKPRSLRF 620
           STNLFSKLTSKLTR                        SRNVSAEQKDENKEAKPRSLRF
Sbjct: 601 STNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRF 660

Query: 621 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL 680
           TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL
Sbjct: 661 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL 720

Query: 681 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL 713
           PRLSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 721 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL 753


>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
           sapiens]
          Length = 795

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 553/811 (68%), Positives = 610/811 (75%), Gaps = 114/811 (14%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59

Query: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119

Query: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179

Query: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVD 235
           HRDLKAENLLLD DMNIKIADFGFSNEFTVG KLDTFCGSPPYAAPELFQGKKYDGPEVD
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD 239

Query: 236 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
           VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKR
Sbjct: 240 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKR 299

Query: 296 GTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYD 355
           G+LEQIMKDRW+N GHEE+ELKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYD
Sbjct: 300 GSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYD 359

Query: 356 EITATYLLLGRKSSEV---------------RPSSDLNNSTGQSPHH-KVQRSVFSSQKQ 399
           E+ ATY+LLGRK  E                RPSSDLNNST QSP H KVQRS+ ++QKQ
Sbjct: 360 EVMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQ 419

Query: 400 RRYSDHAGPAIPSVVAYPKRSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPMLG 457
           RR+SDHAGP+IP  V+Y KR Q ++ +S+ KE  D   +RK   + VG K    ASP++G
Sbjct: 420 RRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVG 479

Query: 458 NASNPNKADIPERKKSSTVPSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENS--- 513
                     PERKKSST+PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S   
Sbjct: 480 ----------PERKKSSTIPSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLTE 527

Query: 514 ----------------------------------------TIPD----------QRTPVA 523
                                                   TI D          QR P A
Sbjct: 528 MSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAA 587

Query: 524 --STHSISSAATPDRIRFPRGTASRSTFHG-QPRERRTATYNGPPASPSLSHEATPLSQT 580
             S HSIS+ ATPDR RFPRG++SRSTFHG Q RERR+  YNGPPASP  SHE    +  
Sbjct: 588 SPSAHSIST-ATPDRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASP--SHETGAFAHA 644

Query: 581 RSRGSTNLFSKLTSKLTR--------------SRNVSAE----QKDENKEAKPRSLRFTW 622
           R   ST + SK+TSK  R              SR+ S E     K+E K++KPRSLRFTW
Sbjct: 645 RRGTSTGIISKITSKFVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTW 704

Query: 623 SMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPR 682
           SMKTTSSMDP DMMREIRKVLDANNCDYEQ+ERFLLFCVHGD   ++LVQWEMEVCKLPR
Sbjct: 705 SMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPR 764

Query: 683 LSLNGVRFKRISGTSIAFKNIASKIANELKL 713
           LSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 765 LSLNGVRFKRISGTSIAFKNIASKIANELKL 795


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score =  910 bits (2353), Expect = 0.0
 Identities = 500/736 (67%), Positives = 572/736 (77%), Gaps = 53/736 (7%)

Query: 2   STRTPLPTVNERDTENHT-SHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           S RTPLPT+NERDTE  T  H D +    S   R     RNS A+ ADEQPHIGNYRLLK
Sbjct: 3   SARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRG----RNS-ATSADEQPHIGNYRLLK 57

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTG+EVA+KIIDKTQLN +SLQKLFREVRIMK+LNHPNIVKLFE
Sbjct: 58  TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 117

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IVHRDLK
Sbjct: 118 VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLK 177

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 178 AENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+FL+LNP KRGTLEQ
Sbjct: 238 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 297

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRW+N GHE+DELKP+VEP  D  D +R ++MV MGY++EEIQ+SL   +Y+E+ AT
Sbjct: 298 IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMAT 357

Query: 361 YLLLGRKSSEV---------RPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIP 411
           YLLLG KSSE+         RPS+DL NS+  SP HKVQRSV ++ KQRR+SD AGPAIP
Sbjct: 358 YLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIP 417

Query: 412 SVVAYPKRSQTSTADSDL-KEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPER 470
           +  +Y K++Q++ A++   +ED  S RK+S +A       PASP+ G           ER
Sbjct: 418 TSNSYSKKTQSNNAENKRPEEDRESGRKASSTAK-----VPASPLPG----------LER 462

Query: 471 KKSSTVPSSNTASGGMTRRN-TYVCSERTTADRHSVIQNGKENSTIPDQRTPVA--STHS 527
           KK++  PS+N+     T R+      ER +  + S IQNGK+ ST P QR PVA  S H+
Sbjct: 463 KKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS-IQNGKD-STAP-QRVPVASPSAHN 519

Query: 528 ISSA-ATPDRIRFPRGTASRSTFHG----QPRERRTATYNGPPASPSLSHEATPLSQTRS 582
           ISS+   PDR  FPRG +SRSTFH     Q R+++   Y   PASPS  H     SQ R 
Sbjct: 520 ISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS-GH-----SQGRR 573

Query: 583 RGSTNLFSKLTSKLTRSRNV-----SAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMR 637
             S ++FSK TSK  R  +V     + ++K+E +EAKPRSLRFTWSMKTTSSM+P +MMR
Sbjct: 574 GASGSIFSKFTSKFVRRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMR 633

Query: 638 EIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTS 697
           EIRKVLDAN+C  E  E+++L C+HG    E+ VQWEMEVCKLPRLSLNGVRFKRISGTS
Sbjct: 634 EIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTS 693

Query: 698 IAFKNIASKIANELKL 713
           +AFKNIASKIANELKL
Sbjct: 694 MAFKNIASKIANELKL 709


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score =  904 bits (2336), Expect = 0.0
 Identities = 501/752 (66%), Positives = 573/752 (76%), Gaps = 70/752 (9%)

Query: 2   STRTPLPTVNERDTENHT-SHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           S RTPLPT+NERDTE  T  H D +    S   R     RNS A+ ADEQPHIGNYRLLK
Sbjct: 3   SARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRG----RNS-ATSADEQPHIGNYRLLK 57

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTG+EVA+KIIDKTQLN +SLQKLFREVRIMK+LNHPNIVKLFE
Sbjct: 58  TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 117

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IVHRDLK
Sbjct: 118 VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLK 177

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 178 AENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+FL+LNP KRGTLEQ
Sbjct: 238 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 297

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRW+N GHE+DELKP+VEP  D  D +R ++MV MGY++EEIQ+SL   +Y+E+ AT
Sbjct: 298 IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMAT 357

Query: 361 YLLLGRKSSEV---------RPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIP 411
           YLLLG KSSE+         RPS+DL NS+  SP HKVQRSV ++ KQRR+SD AGPAIP
Sbjct: 358 YLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIP 417

Query: 412 SVVAYPKRSQTSTADSDL-KEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPER 470
           +  +Y K++Q++ A++   +ED  S RK+S +A       PASP+ G           ER
Sbjct: 418 TSNSYSKKTQSNNAENKRPEEDRESGRKASSTAK-----VPASPLPG----------LER 462

Query: 471 KKSSTVPSSNTASGGMTRRN-TYVCSERTTADRHSVIQNGKENSTIPDQRTPVA--STHS 527
           KK++  PS+N+     T R+      ER +  + S IQNGK+ ST P QR PVA  S H+
Sbjct: 463 KKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS-IQNGKD-STAP-QRVPVASPSAHN 519

Query: 528 ISSA-ATPDRIRFPRGTASRSTFHG----QPRERRTATYNGPPASPSLSHEATPLSQTRS 582
           ISS+   PDR  FPRG +SRSTFH     Q R+++   Y   PASPS  H     SQ R 
Sbjct: 520 ISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS-GH-----SQGRR 573

Query: 583 RGSTNLFSKLTSKLTRSRNVSA---------------------EQKDENKEAKPRSLRFT 621
             S ++FSK TSK  R RN++                      ++K+E +EAKPRSLRFT
Sbjct: 574 GASGSIFSKFTSKFVR-RNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFT 632

Query: 622 WSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLP 681
           WSMKTTSSM+P +MMREIRKVLDAN+C  E  E+++L C+HG    E+ VQWEMEVCKLP
Sbjct: 633 WSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLP 692

Query: 682 RLSLNGVRFKRISGTSIAFKNIASKIANELKL 713
           RLSLNGVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 693 RLSLNGVRFKRISGTSMAFKNIASKIANELKL 724


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score =  902 bits (2332), Expect = 0.0
 Identities = 502/747 (67%), Positives = 573/747 (76%), Gaps = 65/747 (8%)

Query: 2   STRTPLPTVNERDTENHT-SHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           S RTPLPT+NERDTE  T  H D +    S   R     RNS A+ ADEQPHIGNYRLLK
Sbjct: 3   SARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRG----RNS-ATSADEQPHIGNYRLLK 57

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTG+EVA+KIIDKTQLN +SLQKLFREVRIMK+LNHPNIVKLFE
Sbjct: 58  TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 117

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IVHRDLK
Sbjct: 118 VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLK 177

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 178 AENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+FL+LNP KRGTLEQ
Sbjct: 238 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 297

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRW+N GHE+DELKP+VEP  D  D +R ++MV MGY++EEIQ+SL   +Y+E+ AT
Sbjct: 298 IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMAT 357

Query: 361 YLLLGRKSSEV---------RPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDH-AGPAI 410
           YLLLG KSSE+         RPS+DL NS+  SP HKVQRSV ++ KQRR+SD  AGPAI
Sbjct: 358 YLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAI 417

Query: 411 PSVVAYPKRSQTSTADSDL-KEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPE 469
           P+  +Y K++Q++ A++   +ED  S RK+S +A       PASP+ G           E
Sbjct: 418 PTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAK-----VPASPLPG----------LE 462

Query: 470 RKKSSTVPSSNTASGGMTRRN-TYVCSERTTADRHSVIQNGKENSTIPDQRTPVA--STH 526
           RKK++  PS+N+     T R+      ER +  + S IQNGK+ ST P QR PVA  S H
Sbjct: 463 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS-IQNGKD-STAP-QRVPVASPSAH 519

Query: 527 SISSA-ATPDRIRFPRGTASRSTFHG----QPRERRTATYNGPPASPSLSHEATPLSQTR 581
           +ISS+   PDR  FPRG +SRSTFH     Q R+++   Y   PASPS  H     SQ R
Sbjct: 520 NISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS-GH-----SQGR 573

Query: 582 SRGSTNLFSKLTSKLTRSRNVS---------------AEQKDENKEAKPRSLRFTWSMKT 626
              S ++FSK TSK  R RN+S                ++K+E +EAKPRSLRFTWSMKT
Sbjct: 574 RGASGSIFSKFTSKFVR-RNLSFRFARRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKT 632

Query: 627 TSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLN 686
           TSSM+P +MMREIRKVLDAN+C  E  E+++L C+HG    E+ VQWEMEVCKLPRLSLN
Sbjct: 633 TSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLN 692

Query: 687 GVRFKRISGTSIAFKNIASKIANELKL 713
           GVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 693 GVRFKRISGTSMAFKNIASKIANELKL 719


>gi|193083131 MAP/microtubule affinity-regulating kinase 3 isoform e
           [Homo sapiens]
          Length = 659

 Score =  889 bits (2298), Expect = 0.0
 Identities = 456/483 (94%), Positives = 458/483 (94%), Gaps = 25/483 (5%)

Query: 256 QNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDE 315
           ++LKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDE
Sbjct: 177 RDLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDE 236

Query: 316 LKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE----- 370
           LKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE     
Sbjct: 237 LKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASD 296

Query: 371 -----------VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKR 419
                      VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKR
Sbjct: 297 SSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKR 356

Query: 420 SQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSS 479
           SQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSS
Sbjct: 357 SQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSS 416

Query: 480 NTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRF 539
           NTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRF
Sbjct: 417 NTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRF 476

Query: 540 PRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTR- 598
           PRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTR 
Sbjct: 477 PRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRR 536

Query: 599 --------SRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDY 650
                   SRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDY
Sbjct: 537 NMSFRFIKSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDY 596

Query: 651 EQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE 710
           EQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE
Sbjct: 597 EQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE 656

Query: 711 LKL 713
           LKL
Sbjct: 657 LKL 659



 Score =  360 bits (924), Expect = 3e-99
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
Sbjct: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
Sbjct: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180


>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
           [Homo sapiens]
          Length = 788

 Score =  880 bits (2274), Expect = 0.0
 Identities = 501/814 (61%), Positives = 574/814 (70%), Gaps = 130/814 (15%)

Query: 2   STRTPLPTVNERDTENHT-SHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 60
           S RTPLPT+NERDTE  T  H D +    S   R     RNS A+ ADEQPHIGNYRLLK
Sbjct: 3   SARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRG----RNS-ATSADEQPHIGNYRLLK 57

Query: 61  TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 120
           TIGKGNFAKVKLARHILTG+EVA+KIIDKTQLN +SLQKLFREVRIMK+LNHPNIVKLFE
Sbjct: 58  TIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE 117

Query: 121 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 180
           VIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IVHRDLK
Sbjct: 118 VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLK 177

Query: 181 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
           AENLLLDADMNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
Sbjct: 178 AENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237

Query: 241 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
           VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+FL+LNP KRGTLEQ
Sbjct: 238 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 297

Query: 301 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 360
           IMKDRW+N GHE+DELKP+VEP  D  D +R ++MV MGY++EEIQ+SL   +Y+E+ AT
Sbjct: 298 IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMAT 357

Query: 361 YLLLGRKSSEV---------RPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHA-GPAI 410
           YLLLG KSSE+         RPS+DL NS+  SP HKVQRSV ++ KQRR+SD A GPAI
Sbjct: 358 YLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAI 417

Query: 411 PSVVAYPKRSQTSTADSDL-KEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPE 469
           P+  +Y K++Q++ A++   +ED  S RK+S +A       PASP+ G           E
Sbjct: 418 PTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAK-----VPASPLPGL----------E 462

Query: 470 RKKSSTVPSSNTASGGMTRRN-TYVCSERTTADRHSVIQNGKENSTIPD----------- 517
           RKK++  PS+N+     T R+      ER +  + S IQNGK++ T+P            
Sbjct: 463 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS-IQNGKDSLTMPGSRASTASASAA 521

Query: 518 -----------------------------------------QRTPVAS--THSISSAA-T 533
                                                    QR PVAS   H+ISS+   
Sbjct: 522 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA 581

Query: 534 PDRIRFPRGTASRSTFHG----QPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLF 589
           PDR  FPRG +SRSTFH     Q R+++   Y   PASPS  H     SQ R   S ++F
Sbjct: 582 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS-GH-----SQGRRGASGSIF 635

Query: 590 SKLTSKLTRSRNVS------------------------------AEQKDENKEAKPRSLR 619
           SK TSK  R RN+S                               ++K+E +EAKPRSLR
Sbjct: 636 SKFTSKFVR-RNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLR 694

Query: 620 FTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCK 679
           FTWSMKTTSSM+P +MMREIRKVLDAN+C  E  E+++L C+HG    E+ VQWEMEVCK
Sbjct: 695 FTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCK 754

Query: 680 LPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 713
           LPRLSLNGVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 755 LPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 788


>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
           [Homo sapiens]
          Length = 745

 Score =  865 bits (2235), Expect = 0.0
 Identities = 483/767 (62%), Positives = 555/767 (72%), Gaps = 115/767 (14%)

Query: 38  RCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL 97
           R RNS A+ ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTG+EVA+KIIDKTQLN +SL
Sbjct: 3   RGRNS-ATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL 61

Query: 98  QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARS 157
           QKLFREVRIMK+LNHPNIVKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+
Sbjct: 62  QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 121

Query: 158 KFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPP 217
           KFRQIVSAVQYCHQK IVHRDLKAENLLLDADMNIKIADFGFSNEFT G KLDTFCGSPP
Sbjct: 122 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPP 181

Query: 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 277
           YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS
Sbjct: 182 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 241

Query: 278 TDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVG 337
           TDCENLLK+FL+LNP KRGTLEQIMKDRW+N GHE+DELKP+VEP  D  D +R ++MV 
Sbjct: 242 TDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVS 301

Query: 338 MGYSQEEIQESLSKMKYDEITATYLLLGRKSSEV---------RPSSDLNNSTGQSPHHK 388
           MGY++EEIQ+SL   +Y+E+ ATYLLLG KSSE+         RPS+DL NS+  SP HK
Sbjct: 302 MGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHK 361

Query: 389 VQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDL-KEDGISSRKSSGSAVGGK 447
           VQRSV ++ KQRR+SD AGPAIP+  +Y K++Q++ A++   +ED  S RK+S +A    
Sbjct: 362 VQRSVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAK--- 418

Query: 448 GIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRN-TYVCSERTTADRHSVI 506
              PASP+ G           ERKK++  PS+N+     T R+      ER +  + S I
Sbjct: 419 --VPASPLPGL----------ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS-I 465

Query: 507 QNGKENSTIPD------------------------------------------------- 517
           QNGK++ T+P                                                  
Sbjct: 466 QNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPS 525

Query: 518 ---QRTPVAS--THSISSAA-TPDRIRFPRGTASRSTFHG----QPRERRTATYNGPPAS 567
              QR PVAS   H+ISS+   PDR  FPRG +SRSTFH     Q R+++   Y   PAS
Sbjct: 526 TAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPAS 585

Query: 568 PSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSRNVSA---------------------EQ 606
           PS  H     SQ R   S ++FSK TSK  R RN++                      ++
Sbjct: 586 PS-GH-----SQGRRGASGSIFSKFTSKFVR-RNLNEPESKDRVETLRPHVVGSGGNDKE 638

Query: 607 KDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGH 666
           K+E +EAKPRSLRFTWSMKTTSSM+P +MMREIRKVLDAN+C  E  E+++L C+HG   
Sbjct: 639 KEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPG 698

Query: 667 AENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 713
            E+ VQWEMEVCKLPRLSLNGVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 699 HEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 745


>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
           sapiens]
          Length = 688

 Score =  797 bits (2058), Expect = 0.0
 Identities = 431/671 (64%), Positives = 513/671 (76%), Gaps = 35/671 (5%)

Query: 1   MSTRTPLPTVNERDTENHTSHGDGRQ--EVTSRTSRS-GARCRNSIASCADEQPHIGNYR 57
           MS+RT L   N+R+++ H + G GR   +  S +SRS GARCRNSIASC +EQPH+GNYR
Sbjct: 1   MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYR 60

Query: 58  LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
           LL+TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNP+SLQKLFREVRIMK LNHPNIVK
Sbjct: 61  LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120

Query: 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHR 177
           LFEVIETEKTLYL+MEYAS GEVFDYLV+HGRMKEKEAR+KFRQIVSAV YCHQK IVHR
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHR 180

Query: 178 DLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 237
           DLKAENLLLDA+ NIKIADFGFSNEFT+G KLDTFCGSPPYAAPELFQGKKYDGPEVD+W
Sbjct: 181 DLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIW 240

Query: 238 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGT 297
           SLGVILYTLVSGSLPFDG NLKELRERVLRGKYR+PFYMSTDCE++L+RFLVLNP KR T
Sbjct: 241 SLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCT 300

Query: 298 LEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEI 357
           LEQIMKD+WIN G+E +ELKP+ EPE D  D KRI++MVGMGY++EEI+ESL+  KY+E+
Sbjct: 301 LEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEV 360

Query: 358 TATYLLLGRKSSE-------------VRPSSDLNNSTGQS---PHHKVQRSVFSS-QKQR 400
           TATYLLLGRK+ E             VR  SD  N T  S    H K QRS  S+  +QR
Sbjct: 361 TATYLLLGRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKGTSHSKGQRSSSSTYHRQR 420

Query: 401 RYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAV--GGKGIAPASPMLGN 458
           R+SD  GP+      +PKRS TST +++LKE+ +  RK+S S    G +G+ P+SPM+ +
Sbjct: 421 RHSDFCGPS--PAPLHPKRSPTSTGEAELKEERLPGRKASCSTAGSGSRGLPPSSPMVSS 478

Query: 459 ASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQ 518
           A NPNKA+IPER+K ST   +N     MTRRNTYVC+ER  A+R S++ NGKENS+    
Sbjct: 479 AHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGAERPSLLPNGKENSS-GTP 537

Query: 519 RTPVASTHSISSA-ATPDRIRFPRGTASRSTFH-GQPRERRT------ATYNGPPASPSL 570
           R P AS  S S A  + +R R  RG+  RSTFH GQ R+RR          NGPPASP+L
Sbjct: 538 RVPPASPSSHSLAPPSGERSRLARGSTIRSTFHGGQVRDRRAGGGGGGGVQNGPPASPTL 597

Query: 571 SHEATPLSQTRSRGSTNLFSKLTSKLTRSRNVS-AEQKDENKEAKPRSLRFTWSMKT-TS 628
           +HEA PL   R R +TNLF+KLTSKLTR   +  +++++ N+     SL     +++ T+
Sbjct: 598 AHEAAPLPAGRPRPTTNLFTKLTSKLTRRVTLDPSKRQNSNRCVSGASLPQGSKIRSQTN 657

Query: 629 SMDPGDMMREI 639
             + GD+  ++
Sbjct: 658 LRESGDLRSQV 668


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score =  381 bits (978), Expect = e-105
 Identities = 186/320 (58%), Positives = 245/320 (76%), Gaps = 8/320 (2%)

Query: 53  IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
           IG Y + +TIGKGNFA VK A H++T  +VAIKIIDKTQL+  +L+K+FREV+IMK+L H
Sbjct: 5   IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCH 64

Query: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
           P+I++L++V+ETE+ +YL+ EYASGGE+FD+LVAHGRM EKEAR KF+QIV+AV +CH +
Sbjct: 65  PHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCR 124

Query: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
            IVHRDLKAENLLLDA++NIKIADFGFSN FT G  L T+CGSPPYAAPELF+GK+YDGP
Sbjct: 125 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 184

Query: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
           +VD+WSLGV+LY LV G+LPFDG  L+ LR RVL GK+RIPF+MST+CE+L++  LVL+P
Sbjct: 185 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDP 244

Query: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRID--------IMVGMGYSQEE 344
            KR ++EQI K +W+  G  +      +     + +++++D         M  MG  +E+
Sbjct: 245 NKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQ 304

Query: 345 IQESLSKMKYDEITATYLLL 364
             +SL    YD  +A Y LL
Sbjct: 305 TLQSLRSDAYDHYSAIYSLL 324


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score =  355 bits (910), Expect = 1e-97
 Identities = 176/327 (53%), Positives = 238/327 (72%), Gaps = 5/327 (1%)

Query: 53  IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
           +G Y +  T+GKGNFA VKL RH +T  EVAIKIIDK+QL+  +L+K++REV+IMK+L+H
Sbjct: 17  VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 76

Query: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
           P+I+KL++V+ET+  LYL+ EYA  GE+FDYL  HGR+ E EAR KF QI+SAV YCH +
Sbjct: 77  PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136

Query: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
           +IVHRDLKAENLLLD +MNIKIADFGF N F  G  L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 196

Query: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
           ++D+WS+GV+LY LV G+LPFDG  L  LR+RVL G++RIP++MS DCE+L++R LVL+P
Sbjct: 197 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 256

Query: 293 IKRGTLEQIMKDRW--INAGHEEDELKPFV---EPELDISDQKRIDIMVGMGYSQEEIQE 347
            KR T+ QI + +W  I    +   L P     EP +   +++ + +M  +G  Q++  E
Sbjct: 257 SKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIE 316

Query: 348 SLSKMKYDEITATYLLLGRKSSEVRPS 374
           SL    Y+   A Y LL  +    R S
Sbjct: 317 SLQNKSYNHFAAIYFLLVERLKSHRSS 343


>gi|116256471 SNF1-like kinase [Homo sapiens]
          Length = 783

 Score =  352 bits (903), Expect = 7e-97
 Identities = 173/329 (52%), Positives = 238/329 (72%), Gaps = 12/329 (3%)

Query: 53  IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
           +G Y + +T+GKGNFA VKLARH +T  +VAIKIIDKT+L+ ++L+K++REV++MK+LNH
Sbjct: 24  VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 83

Query: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
           P+I+KL++V+ET+  LY++ E+A  GE+FDYL ++G + E EAR KF QI+SAV+YCH  
Sbjct: 84  PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143

Query: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
            IVHRDLK ENLLLD +M+IK+ADFGF N +  G  L T+CGSPPYAAPE+F+GK+Y+GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203

Query: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
           ++D+WSLGV+LY LV GSLPFDG NL  LR+RVL G++RIPF+MS DCE+L++R LV++P
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263

Query: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEP---------ELDISDQKRIDIMVGMGYSQE 343
            +R T+ QI + RW+ A   E  L     P          L   D++ + IM  +G  ++
Sbjct: 264 ARRITIAQIRQHRWMRA---EPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQ 320

Query: 344 EIQESLSKMKYDEITATYLLLGRKSSEVR 372
              ESL    Y+   A Y LL  +  E R
Sbjct: 321 RTVESLQNSSYNHFAAIYYLLLERLKEYR 349


>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
          Length = 651

 Score =  289 bits (739), Expect = 7e-78
 Identities = 211/670 (31%), Positives = 333/670 (49%), Gaps = 41/670 (6%)

Query: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115
           Y L +TIG G FAKVKLA HILTG  VAIKI+DK  L  + L ++  E+  +K L H +I
Sbjct: 11  YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69

Query: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
            +L+ V+ET   +++++EY  GGE+FDY+++  R+ E+E R  FRQIVSAV Y H +   
Sbjct: 70  CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129

Query: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYDGP 232
           HRDLK ENLL D    +K+ DFG   +   G K   L T CGS  YAAPEL QGK Y G 
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188

Query: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
           E DVWS+G++LY L+ G LPFD  N+  L ++++RGKY +P ++S     LL++ L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248

Query: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKM 352
            KR +++ ++   WI   +          P + + D    ++ V    +++ +++ +S  
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 308

Query: 353 KYDEITATYLLLGRKSSEVRP-SSDLNN-STGQSPHHKVQRSVFSSQKQRRYSDHAGPAI 410
           +YD +TATYLLL  K +  +P    L++ S GQ+       + F+  K   +S      +
Sbjct: 309 QYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQA-----SATPFTDIKSNNWS------L 357

Query: 411 PSVVAYPKRSQTSTADSDLKEDGISS-----RKSSGSAVGGKGIAPASPMLGNASNPNKA 465
             V A  K       D D  ED +S+     R S  +    +     S  L  A     A
Sbjct: 358 EDVTASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPA 417

Query: 466 DIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAST 525
           +  + K++   P S      +     ++  E  T    +  Q+ +E  T P++ T  +  
Sbjct: 418 NKLKNKENVYTPKS-----AVKNEEYFMFPEPKTPVNKN--QHKREILTTPNRYTTPSKA 470

Query: 526 HSISSAATPDRIRF-PRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 584
            +     TP +I     GT    T    P ERR         S  L      + +T  R 
Sbjct: 471 RNQCLKETPIKIPVNSTGTDKLMTGVISP-ERRC-------RSVELDLNQAHMEETPKRK 522

Query: 585 STNLFSKLTSKLTRSRNVSAEQKDENKEAK-PRSLRFTWSMKTTSSMDPGDMMREIRKVL 643
              +F  L   L +   V    K +      PR L+  +++ TT  ++P  ++ EI  +L
Sbjct: 523 GAKVFGSLERGLDKVITVLTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSIL 582

Query: 644 DANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNI 703
              + D+ Q+  + L C       +  +Q+E+EVC+L +  + G+R +R+ G +  +K +
Sbjct: 583 PKKHVDFVQK-GYTLKCQTQSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRL 641

Query: 704 ASKIANELKL 713
              I +  K+
Sbjct: 642 VEDILSSCKV 651


>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
          Length = 778

 Score =  288 bits (737), Expect = 1e-77
 Identities = 203/579 (35%), Positives = 300/579 (51%), Gaps = 62/579 (10%)

Query: 52  HIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILN 111
           ++G YRL KT+GKG    VKL  H +TG++VAIKI+++ +L+ + L K+ RE+ I+K++ 
Sbjct: 30  YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89

Query: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQ 171
           HP+++KL +V E +K LYL++E+ SGGE+FDYLV  GR+  KEAR  FRQIVSA+ +CH 
Sbjct: 90  HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149

Query: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
             I HRDLK ENLLLD   NI+IADFG ++       L+T CGSP YA PE+ +G+KYDG
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 209

Query: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291
              D+WS GVIL+ L+ G+LPFD  NL++L E+V RG + +P ++  DC++LL+  + + 
Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269

Query: 292 PIKRGTLEQIMKDRWINAG-HEEDELKPFVEP---------------ELDISDQKRIDIM 335
           P KR +LEQI K  W   G HE D   P +EP               ELD  D       
Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEPD---PCLEPAPGRRVAMRSLPSNGELD-PDVLESMAS 325

Query: 336 VGMGYSQEEIQESL-SKMKYDEITATYLLLGRK-------SSEVRPSSDLNNSTGQSPHH 387
           +G    +E +   L S+ +  E    YLLL RK         ++ P +D++      P  
Sbjct: 326 LGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVD-----PPRK 380

Query: 388 KVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADS-DLKEDGISSRKSSGSAVGG 446
           +V   + S   +RR    +   +    A    S   T  + ++ +    SR  SG++ G 
Sbjct: 381 RVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGL 440

Query: 447 KG---IAPASPMLGNASNPNKADIPE-----RKKSSTVPSSNTASGGM-------TRRNT 491
                 +P SP+   +  P   D          K+ T+PS     GG        + R+T
Sbjct: 441 SSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARST 500

Query: 492 YV----CSERTTADR--HSVIQNGKENST-IPDQRTPVASTHSISSAATPDRIRFPRGTA 544
            +     S R++     HS +   + + T  P    P +    +  AA   R+      +
Sbjct: 501 PLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRL-----NS 555

Query: 545 SRSTFHGQPR-ERRTATYNGPPASPSLSHEATPLSQTRS 582
            R++F G PR  RR           SL+ E++P    RS
Sbjct: 556 IRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRS 594


>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
          Length = 668

 Score =  283 bits (723), Expect = 5e-76
 Identities = 166/437 (37%), Positives = 249/437 (56%), Gaps = 13/437 (2%)

Query: 47  ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRI 106
           A    ++G YRL KT+GKG    VKL  H +T ++VAIKI+++ +L+ + L K+ RE+ I
Sbjct: 10  AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAI 69

Query: 107 MKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
           +K++ HP+++KL +V E +K LYL++E+ SGGE+FDYLV  GR+  KEAR  FRQI+SA+
Sbjct: 70  LKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISAL 129

Query: 167 QYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQG 226
            +CH   I HRDLK ENLLLD   NI+IADFG ++       L+T CGSP YA PE+ +G
Sbjct: 130 DFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRG 189

Query: 227 KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
           +KYDG + DVWS GVIL+ L+ G+LPFD  NL++L E+V RG + +P ++  DC++LL+ 
Sbjct: 190 EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRG 249

Query: 287 FLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVE--------PELDISDQKRIDIMVGM 338
            + ++  +R TLE I K  W   G  E E +  +         P L+  D   +D M  +
Sbjct: 250 MIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSL 309

Query: 339 GYSQEE---IQESLSKMKYDEITATYLLLGRKSS-EVRPSSDLNNSTGQSPHHKVQRSVF 394
           G  ++    +Q+ LS+ +  E    +LLL RK     +   DL       P  K   S  
Sbjct: 310 GCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPM 369

Query: 395 SSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASP 454
            ++  +R  +     + SV           A  ++ + G  SR  SG++ G      +SP
Sbjct: 370 LNRHGKRRPERKSMEVLSVTDGGSPVPARRA-IEMAQHGQRSRSISGASSGLSTSPLSSP 428

Query: 455 MLGNASNPNKADIPERK 471
            +    +P  + +P  K
Sbjct: 429 RVTPHPSPRGSPLPTPK 445


>gi|156105707 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  268 bits (685), Expect = 1e-71
 Identities = 143/346 (41%), Positives = 214/346 (61%), Gaps = 10/346 (2%)

Query: 54  GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHP 113
           G Y L KT+G+G+FA VKLARH+ TG +VA+K+IDKT+L+  +   LF+EVR MK++ HP
Sbjct: 14  GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73

Query: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGR-MKEKEARSKFRQIVSAVQYCHQK 172
           NIV+L+EVI+T+  LYLI+E   GG++FDY++ H   + E  A+  F QIV A+ YCH+ 
Sbjct: 74  NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133

Query: 173 RIVHRDLKAENLL-LDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
            +VHRDLK EN++  +    +K+ DFGFSN+F  G KL T CGS  Y+APE+  G +YD 
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193

Query: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291
           P VD+WSLGVIL+ LV G  PF   N  E    ++  KY +P ++S +C++L+ R L  +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253

Query: 292 PIKRGTLEQIMKDRWINAGHEEDELK---PFVEPELDISDQKRIDI----MVGMGYSQEE 344
           P +R +LE+I    W+         K   P V  + ++S+++   I    ++G    ++ 
Sbjct: 254 PKRRASLEEIENHPWLQGVDPSPATKYNIPLVSYK-NLSEEEHNSIIQRMVLGDIADRDA 312

Query: 345 IQESLSKMKYDEITATYLLLGRKSSEVRPSSDLNNSTGQSPHHKVQ 390
           I E+L   +Y+ ITATY LL  +    +   ++   +    + K Q
Sbjct: 313 IVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQ 358


>gi|156105705 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  268 bits (685), Expect = 1e-71
 Identities = 143/346 (41%), Positives = 214/346 (61%), Gaps = 10/346 (2%)

Query: 54  GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHP 113
           G Y L KT+G+G+FA VKLARH+ TG +VA+K+IDKT+L+  +   LF+EVR MK++ HP
Sbjct: 14  GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73

Query: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGR-MKEKEARSKFRQIVSAVQYCHQK 172
           NIV+L+EVI+T+  LYLI+E   GG++FDY++ H   + E  A+  F QIV A+ YCH+ 
Sbjct: 74  NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133

Query: 173 RIVHRDLKAENLL-LDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
            +VHRDLK EN++  +    +K+ DFGFSN+F  G KL T CGS  Y+APE+  G +YD 
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193

Query: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291
           P VD+WSLGVIL+ LV G  PF   N  E    ++  KY +P ++S +C++L+ R L  +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253

Query: 292 PIKRGTLEQIMKDRWINAGHEEDELK---PFVEPELDISDQKRIDI----MVGMGYSQEE 344
           P +R +LE+I    W+         K   P V  + ++S+++   I    ++G    ++ 
Sbjct: 254 PKRRASLEEIENHPWLQGVDPSPATKYNIPLVSYK-NLSEEEHNSIIQRMVLGDIADRDA 312

Query: 345 IQESLSKMKYDEITATYLLLGRKSSEVRPSSDLNNSTGQSPHHKVQ 390
           I E+L   +Y+ ITATY LL  +    +   ++   +    + K Q
Sbjct: 313 IVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQ 358


>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
           [Homo sapiens]
          Length = 552

 Score =  266 bits (679), Expect = 6e-71
 Identities = 141/331 (42%), Positives = 207/331 (62%), Gaps = 18/331 (5%)

Query: 47  ADEQPH-----IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KL 100
           A++Q H     IG+Y L  T+G G F KVK+  H LTG +VA+KI+++ ++    +  K+
Sbjct: 2   AEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKI 61

Query: 101 FREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFR 160
            RE++ +K+  HP+I+KL++VI T    +++MEY SGGE+FDY+  HGR++E EAR  F+
Sbjct: 62  KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQ 121

Query: 161 QIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAA 220
           QI+SAV YCH+  +VHRDLK EN+LLDA MN KIADFG SN  + G  L T CGSP YAA
Sbjct: 122 QILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 181

Query: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 280
           PE+  G+ Y GPEVD+WS GVILY L+ G+LPFD +++  L +++  G + IP Y++   
Sbjct: 182 PEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSV 241

Query: 281 ENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRID------I 334
             LL   L ++P+KR T++ I +  W      + +L  ++ PE    D   ID      +
Sbjct: 242 ATLLMHMLQVDPLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVIDDEAVKEV 296

Query: 335 MVGMGYSQEEIQESL-SKMKYDEITATYLLL 364
                 ++ E+  SL S    D++   Y L+
Sbjct: 297 CEKFECTESEVMNSLYSGDPQDQLAVAYHLI 327


>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 1 [Homo sapiens]
          Length = 559

 Score =  263 bits (671), Expect = 5e-70
 Identities = 138/331 (41%), Positives = 209/331 (63%), Gaps = 18/331 (5%)

Query: 47  ADEQPH-----IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KL 100
           A++Q H     IG+Y L  T+G G F KVK+ +H LTG +VA+KI+++ ++    +  K+
Sbjct: 13  AEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKI 72

Query: 101 FREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFR 160
            RE++ +K+  HP+I+KL++VI T   ++++MEY SGGE+FDY+  +GR+ EKE+R  F+
Sbjct: 73  RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQ 132

Query: 161 QIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAA 220
           QI+S V YCH+  +VHRDLK EN+LLDA MN KIADFG SN  + G  L T CGSP YAA
Sbjct: 133 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 192

Query: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 280
           PE+  G+ Y GPEVD+WS GVILY L+ G+LPFD  ++  L +++  G +  P Y++   
Sbjct: 193 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSV 252

Query: 281 ENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPE------LDISDQKRIDI 334
            +LLK  L ++P+KR T++ I +  W      + +L  ++ PE        I D+   ++
Sbjct: 253 ISLLKHMLQVDPMKRATIKDIREHEWF-----KQDLPKYLFPEDPSYSSTMIDDEALKEV 307

Query: 335 MVGMGYSQEEIQESL-SKMKYDEITATYLLL 364
                 S+EE+   L ++   D +   Y L+
Sbjct: 308 CEKFECSEEEVLSCLYNRNHQDPLAVAYHLI 338


>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
          Length = 661

 Score =  262 bits (669), Expect = 9e-70
 Identities = 191/634 (30%), Positives = 294/634 (46%), Gaps = 68/634 (10%)

Query: 8   PTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNF 67
           P   +R      + G  R+ V   T+    R  + +     +      Y L +T+GKG +
Sbjct: 7   PVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTY 66

Query: 68  AKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPNIVKLFEVIETEK 126
            KVK A    +GR VAIK I K ++ +   +  + RE+ IM  LNHP+I+ ++EV E + 
Sbjct: 67  GKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKD 126

Query: 127 TLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLL 186
            + +IMEYAS GE++DY+    R+ E+E R  FRQIVSAV YCH+  +VHRDLK EN+LL
Sbjct: 127 KIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILL 186

Query: 187 DADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 246
           D + NIKIADFG SN +     L TFCGSP YA+PE+  G+ Y GPEVD W+LGV+LYTL
Sbjct: 187 DDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTL 246

Query: 247 VSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRW 306
           V G++PFDG + K L  ++  G+YR P   S D   L++  L++NP +R T+E I    W
Sbjct: 247 VYGTMPFDGFDHKNLIRQISSGEYREPTQPS-DARGLIRWMLMVNPDRRATIEDIANHWW 305

Query: 307 INAGHE---------EDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEI 357
           +N G++          D   P +   +D   +       G+    E   + L+K    E+
Sbjct: 306 VNWGYKSSVCDCDALHDSESPLLARIIDWHHRS-----TGLQADTEAKMKGLAKPTTSEV 360

Query: 358 TATYLLLGRKSSE----VRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSV 413
                   +KS +     +   D    +      K  + +   +    +  H+   I  V
Sbjct: 361 MLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGV 420

Query: 414 VAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPER--- 470
           V  P    T   + DL   G+              + P+SP         +A++P +   
Sbjct: 421 VG-PALPSTFKMEQDLCRTGV--------------LLPSSP---------EAEVPGKLSP 456

Query: 471 KKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTP---VASTHS 527
           K+S+T+P          R + Y  S   +     +  N    S+IP    P     ++HS
Sbjct: 457 KQSATMPKKGILKKTQQRESGYYSSPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHS 516

Query: 528 ISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTN 587
           +S           +G    S+ +              P   SLS    P     + G + 
Sbjct: 517 LSCRR--------KGILKHSSKYSAGTMDPALVSPEMPTLESLSEPGVP-----AEGLSR 563

Query: 588 LFSKLTSKLTRSRNVSAEQKD-----ENKEAKPR 616
            +S+ +S ++    +S++  D     EN+ A+ R
Sbjct: 564 SYSRPSSVISDDSVLSSDSFDLLDLQENRPARQR 597


>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
          Length = 628

 Score =  256 bits (655), Expect = 4e-68
 Identities = 132/257 (51%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 114
           Y  L+T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111

Query: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
           I+ + EV E    + ++MEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ R+
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171

Query: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231

Query: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIK 294
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP +
Sbjct: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290

Query: 295 RGTLEQIMKDRWINAGH 311
           R TLE +    W+N G+
Sbjct: 291 RATLEDVASHWWVNWGY 307


>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
          Length = 436

 Score =  255 bits (652), Expect = 9e-68
 Identities = 129/320 (40%), Positives = 201/320 (62%), Gaps = 8/320 (2%)

Query: 53  IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNH 112
           IG YR+   IG GNF++VKL  H LT  +VAIKI+DKT+L+  + + L RE+  M+ L+H
Sbjct: 71  IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130

Query: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
           PNI++L+EV+ET   L+L+MEYA GGE+F  +   G++ E E++  F QIVSAV++ H+ 
Sbjct: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190

Query: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
           +I+HRDLKAEN+   ++  +K+ DFGFS     G  L+TFCGSPPYAAPELF+ + Y G 
Sbjct: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250

Query: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
            VD+W+LGV+LY +V+G++PF  + + +L++ +L G Y +P ++S  C  L++  L   P
Sbjct: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310

Query: 293 IKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRI--------DIMVGMGYSQEE 344
            +R  ++ IM D W+        L+PF      +S+   +          +  +G ++E 
Sbjct: 311 TERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEH 370

Query: 345 IQESLSKMKYDEITATYLLL 364
           I+ +  +     IT  Y ++
Sbjct: 371 IRNNQGRDARSSITGVYRII 390


>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 2 [Homo sapiens]
          Length = 574

 Score =  253 bits (645), Expect = 6e-67
 Identities = 138/346 (39%), Positives = 209/346 (60%), Gaps = 33/346 (9%)

Query: 47  ADEQPH-----IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KL 100
           A++Q H     IG+Y L  T+G G F KVK+ +H LTG +VA+KI+++ ++    +  K+
Sbjct: 13  AEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKI 72

Query: 101 FREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGR----------- 149
            RE++ +K+  HP+I+KL++VI T   ++++MEY SGGE+FDY+  +GR           
Sbjct: 73  RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTG 132

Query: 150 ----MKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTV 205
               + EKE+R  F+QI+S V YCH+  +VHRDLK EN+LLDA MN KIADFG SN  + 
Sbjct: 133 STKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD 192

Query: 206 GGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 265
           G  L T CGSP YAAPE+  G+ Y GPEVD+WS GVILY L+ G+LPFD  ++  L +++
Sbjct: 193 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 252

Query: 266 LRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPE-- 323
             G +  P Y++    +LLK  L ++P+KR T++ I +  W      + +L  ++ PE  
Sbjct: 253 CDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF-----KQDLPKYLFPEDP 307

Query: 324 ----LDISDQKRIDIMVGMGYSQEEIQESL-SKMKYDEITATYLLL 364
                 I D+   ++      S+EE+   L ++   D +   Y L+
Sbjct: 308 SYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLI 353


>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
           sapiens]
          Length = 714

 Score =  222 bits (566), Expect = 8e-58
 Identities = 160/509 (31%), Positives = 257/509 (50%), Gaps = 65/509 (12%)

Query: 48  DEQPH--IGNYRL-LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL--QKLFR 102
           D Q H  +GNY +  + +G+G+FAKV+   H+LTG +VAIK+IDK +    +   + L R
Sbjct: 51  DFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRR 110

Query: 103 EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQI 162
           E +I +++ HPNI +L +++ETE + YL+ME   GG +   +    R++E EAR   RQ+
Sbjct: 111 EGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQL 170

Query: 163 VSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTF---CGSPPYA 219
           +SAV++ H+  +VHRDLK ENLLLD D NIK+ DFG SN   + G  D F   CGSP YA
Sbjct: 171 ISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYA 230

Query: 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYR-IPFYM 276
           APEL   KKY GP++DVWS+GV +Y +++G+LPF  +  +L+ L ++++  +   +P  +
Sbjct: 231 APELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQL 289

Query: 277 STDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPEL----DISDQKRI 332
           ST   + L+  L  +P+KR  ++Q + +RW+N  +          P      D+S    +
Sbjct: 290 STGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVL 349

Query: 333 DIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE-VRPSSDLNNSTGQSPHHKVQR 391
            +   +GY   ++  ++   +   I A Y LL +K    +   SD+ +S         + 
Sbjct: 350 HMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSL------CYKT 403

Query: 392 SVFSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADS---DLKEDGISSRKSSGSAVGGKG 448
            ++  +K R                PK S  ++ D+   DL+   +  +K       G  
Sbjct: 404 RLYQIEKYRA---------------PKESYEASLDTWTRDLEFHAVQDKKPKEQEKRGDF 448

Query: 449 I----------------APASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTY 492
           +                 P+  ++    N  KA + +RK S    SS         RN +
Sbjct: 449 LHRPFSKKLDKNLPSHKQPSGSLMTQIQN-TKALLKDRKASK---SSFPDKDSFGCRNIF 504

Query: 493 VCSERTTADRHSVIQNGKENSTIPDQRTP 521
               R T+D + V  +  E   +P  RTP
Sbjct: 505 ----RKTSDSNCVASSSMEFIPVPPPRTP 529


>gi|14042947 testis-specific serine kinase 1 [Homo sapiens]
          Length = 367

 Score =  189 bits (479), Expect = 1e-47
 Identities = 104/263 (39%), Positives = 162/263 (61%), Gaps = 13/263 (4%)

Query: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
           Y L   +G+G++AKVK A        VAIKIID+ +     L+K   RE+ I+ +LNH +
Sbjct: 12  YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71

Query: 115 IVKLFEVIETEK-TLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
           I+K +E+ ET    +Y++ME A  G++ + +   G + E EAR KF Q+  A++YCH   
Sbjct: 72  IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131

Query: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEF--TVGGKL---DTFCGSPPYAAPELFQGKK 228
           +VHRDLK +NLLLD D NIK++DF FS        G++    TFCGSP YAAPE+ QG  
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191

Query: 229 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLL 284
           Y     D+WSLGVILY +V GS+P+D  N+K++    ++ ++R+ F    +++ +C++L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLR--IQKEHRVNFPRSKHLTGECKDLI 249

Query: 285 KRFLVLNPIKRGTLEQIMKDRWI 307
              L  +  +R  +++I+   W+
Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWM 272


>gi|16418343 testis-specific serine kinase 3 [Homo sapiens]
          Length = 268

 Score =  188 bits (477), Expect = 2e-47
 Identities = 103/257 (40%), Positives = 163/257 (63%), Gaps = 6/257 (2%)

Query: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
           Y+L KTIG+G ++KVK A      R+VAIK+IDK       +Q+   RE++I++ L+H N
Sbjct: 10  YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69

Query: 115 IVKLFEVIET-EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
           I++++E++E+ +  + L+ME A GG+VFD ++  G + E  A++ FRQ+V A++YCH   
Sbjct: 70  IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129

Query: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK--LDTFCGSPPYAAPELFQGKKYDG 231
           + HRDLK EN LL    N+K+ DFGF+       +    TFCGS  YAAPE+ QG  +D 
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188

Query: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG-KYRIPFYMSTDCENLLKRFLVL 290
            + DVWS+GV+LY ++  SLPFD  ++ ++  +  +G  +     +S DC++LLKR L  
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248

Query: 291 NPIKRGTLEQIMKDRWI 307
           + I R ++E++    W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265


>gi|194294513 testis-specific serine kinase 2 [Homo sapiens]
          Length = 358

 Score =  184 bits (467), Expect = 2e-46
 Identities = 103/258 (39%), Positives = 160/258 (62%), Gaps = 15/258 (5%)

Query: 62  IGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF--REVRIMKILNHPNIVKLF 119
           +GKG++AKVK A        VA+KIID+ +  PT   + F  RE+ I+  +NH +I+K +
Sbjct: 18  LGKGSYAKVKSAYSERLKFNVAVKIIDRKK-TPTDFVERFLPREMDILATVNHGSIIKTY 76

Query: 120 EVIET-EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
           E+ ET +  +Y+IME    G++ +++   G + E  AR  FRQ+ SAV+YCH   IVHRD
Sbjct: 77  EIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRD 136

Query: 179 LKAENLLLDADMNIKIADFGFSNEF--TVGGKL---DTFCGSPPYAAPELFQGKKYDGPE 233
           LK ENLLLD D NIK++DFGFS        G++    TFCGS  YAAPE+ Q   Y    
Sbjct: 137 LKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKV 196

Query: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKRFLV 289
            D+WSLGVILY +V GS+P+D  +++++    ++ ++R+ F     ++ +C++L+ R L 
Sbjct: 197 YDIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQ 254

Query: 290 LNPIKRGTLEQIMKDRWI 307
            +  +R  +++I+   W+
Sbjct: 255 PDVSQRLHIDEILSHSWL 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,730,122
Number of Sequences: 37866
Number of extensions: 1223121
Number of successful extensions: 7408
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 742
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 4193
Number of HSP's gapped (non-prelim): 1531
length of query: 713
length of database: 18,247,518
effective HSP length: 109
effective length of query: 604
effective length of database: 14,120,124
effective search space: 8528554896
effective search space used: 8528554896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.