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Search of human proteins with 190194365
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190194365 PAP associated domain containing 1 [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190194365 PAP associated domain containing 1 [Homo sapiens] 1161 0.0
gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific ... 162 8e-40
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho... 99 8e-21
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho... 97 4e-20
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho... 97 4e-20
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 88 2e-17
gi|167555099 PAP associated domain containing 4 [Homo sapiens] 86 9e-17
gi|167555097 PAP associated domain containing 4 [Homo sapiens] 86 9e-17
gi|167555095 PAP associated domain containing 4 [Homo sapiens] 86 9e-17
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 34 0.32
gi|45935391 coiled-coil domain containing 69 [Homo sapiens] 32 2.1
gi|33946313 ninein isoform 4 [Homo sapiens] 31 3.6
gi|33946321 ninein isoform 5 [Homo sapiens] 31 3.6
gi|148536871 ninein isoform 1 [Homo sapiens] 31 3.6
gi|148536869 ninein isoform 2 [Homo sapiens] 31 3.6
gi|6678271 TAR DNA binding protein [Homo sapiens] 30 4.7
gi|47458825 hypothetical protein LOC144577 [Homo sapiens] 30 4.7
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 30 8.0
gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom... 30 8.0
>gi|190194365 PAP associated domain containing 1 [Homo sapiens]
Length = 582
Score = 1161 bits (3003), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPK 60
MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPK
Sbjct: 1 MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPK 60
Query: 61 RRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQ 120
RRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQ
Sbjct: 61 RRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQ 120
Query: 121 KESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELL 180
KESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELL
Sbjct: 121 KESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELL 180
Query: 181 CYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKL 240
CYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKL
Sbjct: 181 CYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKL 240
Query: 241 GCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCV 300
GCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCV
Sbjct: 241 GCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCV 300
Query: 301 GVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCW 360
GVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCW
Sbjct: 301 GVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCW 360
Query: 361 ARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCT 420
ARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCT
Sbjct: 361 ARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCT 420
Query: 421 FVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPF 480
FVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPF
Sbjct: 421 FVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPF 480
Query: 481 ETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKS 540
ETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKS
Sbjct: 481 ETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKS 540
Query: 541 FTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT 582
FTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT
Sbjct: 541 FTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT 582
>gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific
[Homo sapiens]
Length = 912
Score = 162 bits (410), Expect = 8e-40
Identities = 95/272 (34%), Positives = 154/272 (56%), Gaps = 14/272 (5%)
Query: 277 ERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTS 336
E+ +L ++G L PG VQ + +AR P+V+F H+ SG D++ +NR+AL +
Sbjct: 371 EKAEGAAMLELVGSILRGCVPGVYRVQTVPSARRPVVKFCHRPSGLHGDVSLSNRLALHN 430
Query: 337 SELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPIL 396
S L + LD RVR LV+++RCWA+ L+ S G ++N++LT++VI+FLQ R PP+L
Sbjct: 431 SRFLSLCSELDGRVRPLVYTLRCWAQGRGLSGS--GPLLSNYALTLLVIYFLQTRDPPVL 488
Query: 397 PTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKN 456
PT+ L A ++ ++G +C+F RD SR++PS N E L LL +FF + +
Sbjct: 489 PTVSQLTQKAGEGEQVEVDGWDCSFPRDASRLEPSINVEPLSSLLAQFFSCVSCWDLRGS 548
Query: 457 SINIRQGR----EQNKPDS-------SPLYIQNPFETSLNISKNVSQSQLQKFVDLARES 505
+++R+G+ P + PL +Q+PF+ S N++ NV+ + + R +
Sbjct: 549 LLSLREGQALPVAGGLPSNLWEGLRLGPLNLQDPFDLSHNVAANVTSRVAGRLQNCCRAA 608
Query: 506 AWILQQEDTDRPSISSNRPWGLVSLLLPSAPN 537
A + R S S R WGL+ LL PS+P+
Sbjct: 609 ANYCRSLQYQRRS-SRGRDWGLLPLLQPSSPS 639
Score = 79.7 bits (195), Expect = 7e-15
Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 61 RRFSEMQNERREQAQRTVLIH-CPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFC 119
R E++ R+ Q R+V + P + + +Y FGP+ + + G++A+VE
Sbjct: 79 RHLVELRAARKAQGLRSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKDKGVFAIVE-- 136
Query: 120 QKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFEL 179
+G + S + + R R + K S S+ S + QL +
Sbjct: 137 ----MGDVGAREAVLSQSQHSLGGHRLRVRPREQKEFQSPASK--SPKGAAPDSHQLAKA 190
Query: 180 LCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGK 239
L A + Q+ L+ +L+E +LR L +L++++ +FP C+V PFGSS+N+F
Sbjct: 191 LAEAADVGAQMIKLVGLRELSEAERQLRSLVVALMQEVFTEFFPGCVVHPFGSSINSFDV 250
Query: 240 LGCDLDMFLDLDE 252
GCDLD+FLDL +
Sbjct: 251 HGCDLDLFLDLGD 263
>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
sapiens]
Length = 1640
Score = 99.4 bits (246), Expect = 8e-21
Identities = 87/349 (24%), Positives = 164/349 (46%), Gaps = 53/349 (15%)
Query: 230 FGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLG 289
FGSS N FG DLD+ + L+ N +E++ ++I+ L
Sbjct: 996 FGSSKNGFGFRDSDLDICMTLEGHEN--------------------AEKLNCKEIIENLA 1035
Query: 290 ECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSR 349
+ L PG + I A+ P+V+F H+ SG + D++ N +A ++ +L Y A+D R
Sbjct: 1036 KILKRH-PGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPR 1094
Query: 350 VRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAE 409
V+ L ++++ +A+ + + G+ +++++ +MV++FLQ+R PP++P L +
Sbjct: 1095 VQYLGYTMKVFAKRCDIGDASRGS-LSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIP 1153
Query: 410 DKCVIEGNNCTF---VRDLSRIKPS--QNTETL-ELLLKEFFEYFGNFAFDKNSINIRQG 463
+ +++G N F +L + PS +NTE+L EL L Y F F + I+IRQ
Sbjct: 1154 QR-MVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQK 1212
Query: 464 R----EQNKPDSSPLYIQNPFETSLNISKNVSQSQ----LQKFVD------------LAR 503
+ + + S + I++PF+ + N+ VS+ ++ F++ + R
Sbjct: 1213 KLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGR 1272
Query: 504 ESAWILQQEDTDRPSISSN----RPWGLVSLLLPSAPNRKSFTKKKSNK 548
E+ + ++ N R G + + P RK KK S +
Sbjct: 1273 EAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRKRLKKKDSEE 1321
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 29/208 (13%)
Query: 193 LLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
L KE +T+++ ++R + + + P+C +R +GSS+ F D+
Sbjct: 362 LAKEHGITDDDLRVRQEIVEEMSKVITTFLPECSLRLYGSSLTRFALKSSDV-------- 413
Query: 253 TRNLSAHKISGNFLMEFQVK-NVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCP 311
N ++F K N P I K+L +L + + + V V+ +A+ P
Sbjct: 414 -----------NIDIKFPPKMNHPDLLI---KVLGILKKNVLY-----VDVESDFHAKVP 454
Query: 312 LVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIP 371
+V + SG C ++ N +A +++LL G ++ LV + R WA+ + S
Sbjct: 455 VVVCRDRKSGLLCRVSAGNDMACLTTDLLTALGKIEPVFIPLVLAFRYWAKLCYIDSQTD 514
Query: 372 GAWITNFSLTMMVIFFLQRRSPPILPTL 399
G I ++ +MV+FFLQ+R PP+LP L
Sbjct: 515 GG-IPSYCFALMVMFFLQQRKPPLLPCL 541
>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
sapiens]
Length = 1645
Score = 97.1 bits (240), Expect = 4e-20
Identities = 75/273 (27%), Positives = 140/273 (51%), Gaps = 33/273 (12%)
Query: 230 FGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLG 289
FGSS N FG DLD+ + L+ N +E++ ++I+ L
Sbjct: 996 FGSSKNGFGFRDSDLDICMTLEGHEN--------------------AEKLNCKEIIENLA 1035
Query: 290 ECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSR 349
+ L PG + I A+ P+V+F H+ SG + D++ N +A ++ +L Y A+D R
Sbjct: 1036 KILKRH-PGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPR 1094
Query: 350 VRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAE 409
V+ L ++++ +A+ + + G+ +++++ +MV++FLQ+R PP++P L +
Sbjct: 1095 VQYLGYTMKVFAKRCDIGDASRGS-LSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIP 1153
Query: 410 DKCVIEGNNCTF---VRDLSRIKPS--QNTETL-ELLLKEFFEYFGNFAFDKNSINIRQG 463
+ +++G N F +L + PS +NTE+L EL L Y F F + I+IRQ
Sbjct: 1154 QR-MVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQK 1212
Query: 464 R----EQNKPDSSPLYIQNPFETSLNISKNVSQ 492
+ + + S + I++PF+ + N+ VS+
Sbjct: 1213 KLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSR 1245
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 29/208 (13%)
Query: 193 LLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
L KE +T+++ ++R + + + P+C +R +GSS+ F D+
Sbjct: 362 LAKEHGITDDDLRVRQEIVEEMSKVITTFLPECSLRLYGSSLTRFALKSSDV-------- 413
Query: 253 TRNLSAHKISGNFLMEFQVK-NVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCP 311
N ++F K N P I K+L +L + + + V V+ +A+ P
Sbjct: 414 -----------NIDIKFPPKMNHPDLLI---KVLGILKKNVLY-----VDVESDFHAKVP 454
Query: 312 LVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIP 371
+V + SG C ++ N +A +++LL G ++ LV + R WA+ + S
Sbjct: 455 VVVCRDRKSGLLCRVSAGNDMACLTTDLLTALGKIEPVFIPLVLAFRYWAKLCYIDSQTD 514
Query: 372 GAWITNFSLTMMVIFFLQRRSPPILPTL 399
G I ++ +MV+FFLQ+R PP+LP L
Sbjct: 515 GG-IPSYCFALMVMFFLQQRKPPLLPCL 541
>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
sapiens]
Length = 1644
Score = 97.1 bits (240), Expect = 4e-20
Identities = 75/273 (27%), Positives = 140/273 (51%), Gaps = 33/273 (12%)
Query: 230 FGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLG 289
FGSS N FG DLD+ + L+ N +E++ ++I+ L
Sbjct: 996 FGSSKNGFGFRDSDLDICMTLEGHEN--------------------AEKLNCKEIIENLA 1035
Query: 290 ECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSR 349
+ L PG + I A+ P+V+F H+ SG + D++ N +A ++ +L Y A+D R
Sbjct: 1036 KILKRH-PGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPR 1094
Query: 350 VRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAE 409
V+ L ++++ +A+ + + G+ +++++ +MV++FLQ+R PP++P L +
Sbjct: 1095 VQYLGYTMKVFAKRCDIGDASRGS-LSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIP 1153
Query: 410 DKCVIEGNNCTF---VRDLSRIKPS--QNTETL-ELLLKEFFEYFGNFAFDKNSINIRQG 463
+ +++G N F +L + PS +NTE+L EL L Y F F + I+IRQ
Sbjct: 1154 QR-MVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQK 1212
Query: 464 R----EQNKPDSSPLYIQNPFETSLNISKNVSQ 492
+ + + S + I++PF+ + N+ VS+
Sbjct: 1213 KLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSR 1245
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 29/208 (13%)
Query: 193 LLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
L KE +T+++ ++R + + + P+C +R +GSS+ F D+
Sbjct: 362 LAKEHGITDDDLRVRQEIVEEMSKVITTFLPECSLRLYGSSLTRFALKSSDV-------- 413
Query: 253 TRNLSAHKISGNFLMEFQVK-NVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCP 311
N ++F K N P I K+L +L + + + V V+ +A+ P
Sbjct: 414 -----------NIDIKFPPKMNHPDLLI---KVLGILKKNVLY-----VDVESDFHAKVP 454
Query: 312 LVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIP 371
+V + SG C ++ N +A +++LL G ++ LV + R WA+ + S
Sbjct: 455 VVVCRDRKSGLLCRVSAGNDMACLTTDLLTALGKIEPVFIPLVLAFRYWAKLCYIDSQTD 514
Query: 372 GAWITNFSLTMMVIFFLQRRSPPILPTL 399
G I ++ +MV+FFLQ+R PP+LP L
Sbjct: 515 GG-IPSYCFALMVMFFLQQRKPPLLPCL 541
>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
Length = 1495
Score = 87.8 bits (216), Expect = 2e-17
Identities = 73/308 (23%), Positives = 145/308 (47%), Gaps = 33/308 (10%)
Query: 195 KEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETR 254
K+F T + R +E FP + FGSS N FG DLD+ + ++
Sbjct: 1010 KDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLE 1069
Query: 255 NLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVR 314
+E + + + L L G + I A+ P+V+
Sbjct: 1070 T--------------------AEGLDCVRTIEELARVLRKHS-GLRNILPITTAKVPIVK 1108
Query: 315 FSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAW 374
F H SG + D++ N +AL ++ LL Y A+D RV+ L ++++ + + + + G+
Sbjct: 1109 FFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGS- 1167
Query: 375 ITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRI-----K 429
+++++ T+MV++FLQ+R+PP++P L + + + + ++G N F + + +
Sbjct: 1168 LSSYAYTLMVLYFLQQRNPPVIPVLQEIYK-GEKKPEIFVDGWNIYFFDQIDELPTYWSE 1226
Query: 430 PSQNTETL-ELLLKEFFEYFGNFAFDKNSINIRQ----GREQNKPDSSPLYIQNPFETSL 484
+NTE++ +L L Y F F ++ I+IR+ + + S + I++PF+ +
Sbjct: 1227 CGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNH 1286
Query: 485 NISKNVSQ 492
N+ +S+
Sbjct: 1287 NLGAGLSR 1294
Score = 67.8 bits (164), Expect = 3e-11
Identities = 52/208 (25%), Positives = 95/208 (45%), Gaps = 27/208 (12%)
Query: 190 LNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLD 249
++ +++EF L EN + R ++E++ PDC +R +GSS + G D+++
Sbjct: 299 IDKVVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNI--- 355
Query: 250 LDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNAR 309
+ Q + S+ +L ++ ECL + + V +AR
Sbjct: 356 ------------------DIQFPAIMSQ----PDVLLLVQECLKN-SDSFIDVDADFHAR 392
Query: 310 CPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSS 369
P+V + SG C ++ N A +++ L G L+ ++ LV + R WA+ S+
Sbjct: 393 VPVVVCREKQSGLLCKVSAGNENACLTTKHLTALGKLEPKLVPLVIAFRYWAKLCSIDRP 452
Query: 370 IPGAWITNFSLTMMVIFFLQRRSPPILP 397
G + + +M IFFLQ+R P+LP
Sbjct: 453 EEGG-LPPYVFALMAIFFLQQRKEPLLP 479
>gi|167555099 PAP associated domain containing 4 [Homo sapiens]
Length = 484
Score = 85.9 bits (211), Expect = 9e-17
Identities = 76/319 (23%), Positives = 148/319 (46%), Gaps = 31/319 (9%)
Query: 184 ESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCD 243
+ + Q+ L + Q + K + L + ++ FP + GSS+N FG D
Sbjct: 154 DKLSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSD 213
Query: 244 LDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQ 303
D+ L + E FQV +++ + IL+++ + G +
Sbjct: 214 GDLCLVVKEEPCF------------FQV----NQKTEARHILTLVHKHFCTRLSGYIERP 257
Query: 304 KILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARA 363
+++ A+ P+V+F + S + DL NN + + ++ LL Y L++RVR LV ++ WA
Sbjct: 258 QLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASH 317
Query: 364 HSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSL--KTLADAEDKCVIEGNNCTF 421
H + + G ++++SL +MV+ +LQ PILP+L + ++ + A ++ C
Sbjct: 318 HQINDASRGT-LSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNV 376
Query: 422 VRDLSRIKPSQNTETLELLLKEFFEYFG-NFAFDKNSINIRQGREQNKPD-----SSPLY 475
LS+ N L LL F +Y+ F ++ I++R+ + +PD + +
Sbjct: 377 PPYLSK-----NESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRNKYIC 431
Query: 476 IQNPFETSLNISKNVSQSQ 494
++ PF+ N ++ V + Q
Sbjct: 432 VEEPFD-GTNTARAVHEKQ 449
>gi|167555097 PAP associated domain containing 4 [Homo sapiens]
Length = 484
Score = 85.9 bits (211), Expect = 9e-17
Identities = 76/319 (23%), Positives = 148/319 (46%), Gaps = 31/319 (9%)
Query: 184 ESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCD 243
+ + Q+ L + Q + K + L + ++ FP + GSS+N FG D
Sbjct: 154 DKLSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSD 213
Query: 244 LDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQ 303
D+ L + E FQV +++ + IL+++ + G +
Sbjct: 214 GDLCLVVKEEPCF------------FQV----NQKTEARHILTLVHKHFCTRLSGYIERP 257
Query: 304 KILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARA 363
+++ A+ P+V+F + S + DL NN + + ++ LL Y L++RVR LV ++ WA
Sbjct: 258 QLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASH 317
Query: 364 HSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSL--KTLADAEDKCVIEGNNCTF 421
H + + G ++++SL +MV+ +LQ PILP+L + ++ + A ++ C
Sbjct: 318 HQINDASRGT-LSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNV 376
Query: 422 VRDLSRIKPSQNTETLELLLKEFFEYFG-NFAFDKNSINIRQGREQNKPD-----SSPLY 475
LS+ N L LL F +Y+ F ++ I++R+ + +PD + +
Sbjct: 377 PPYLSK-----NESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRNKYIC 431
Query: 476 IQNPFETSLNISKNVSQSQ 494
++ PF+ N ++ V + Q
Sbjct: 432 VEEPFD-GTNTARAVHEKQ 449
>gi|167555095 PAP associated domain containing 4 [Homo sapiens]
Length = 484
Score = 85.9 bits (211), Expect = 9e-17
Identities = 76/319 (23%), Positives = 148/319 (46%), Gaps = 31/319 (9%)
Query: 184 ESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCD 243
+ + Q+ L + Q + K + L + ++ FP + GSS+N FG D
Sbjct: 154 DKLSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSD 213
Query: 244 LDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQ 303
D+ L + E FQV +++ + IL+++ + G +
Sbjct: 214 GDLCLVVKEEPCF------------FQV----NQKTEARHILTLVHKHFCTRLSGYIERP 257
Query: 304 KILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARA 363
+++ A+ P+V+F + S + DL NN + + ++ LL Y L++RVR LV ++ WA
Sbjct: 258 QLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASH 317
Query: 364 HSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSL--KTLADAEDKCVIEGNNCTF 421
H + + G ++++SL +MV+ +LQ PILP+L + ++ + A ++ C
Sbjct: 318 HQINDASRGT-LSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNV 376
Query: 422 VRDLSRIKPSQNTETLELLLKEFFEYFG-NFAFDKNSINIRQGREQNKPD-----SSPLY 475
LS+ N L LL F +Y+ F ++ I++R+ + +PD + +
Sbjct: 377 PPYLSK-----NESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRNKYIC 431
Query: 476 IQNPFETSLNISKNVSQSQ 494
++ PF+ N ++ V + Q
Sbjct: 432 VEEPFD-GTNTARAVHEKQ 449
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 34.3 bits (77), Expect = 0.32
Identities = 42/184 (22%), Positives = 74/184 (40%), Gaps = 33/184 (17%)
Query: 43 DEQPSGSVETGFEDKIP---KRRFSEMQNERREQAQRTVLIHCPEKISEN---------K 90
+E S VE + K+ K RF+EM+ +R+E+ ++ +I ++ +
Sbjct: 83 EEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRE 142
Query: 91 FLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFN 150
K Q INN E +E SL T P + +T+ + F +
Sbjct: 143 LAKRAEQIEDINN----------TGTESASEEGDDSLLI-TVVPVKSYKTSGKMKKNFED 191
Query: 151 LKLKNQTSER------SRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENT 204
L+ + + ER R+R Q P L E C + +DD++ + K+ L+
Sbjct: 192 LEKEREEKERIKYEEDKRIRYEEQRP----SLKEAKCLSLVMDDEIESEAKKESLSPGKL 247
Query: 205 KLRY 208
KL +
Sbjct: 248 KLTF 251
>gi|45935391 coiled-coil domain containing 69 [Homo sapiens]
Length = 296
Score = 31.6 bits (70), Expect = 2.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 84 EKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIP 143
E I + K++ +G + + E L+ V+E + E I L T E +
Sbjct: 153 ESILSRNYKKHIQDYGSPSQFWEQELESLHFVIEM-KNERIHELDRRLILMETVKEKNLI 211
Query: 144 FRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEEN 203
+ L+ +N E VRS NQ+ S + +LL E+++ ++ L ++ Q +E
Sbjct: 212 LEEKITTLQQEN---EDLHVRSRNQVVLSRQLSEDLLLTREALEKEVQ-LRRQLQQEKEE 267
Query: 204 TKLRYLTCSLIEDMAAAYFPDCIVRP 229
R L + A+ FP V P
Sbjct: 268 LLYRVLGAN-----ASPAFPLAPVTP 288
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 30.8 bits (68), Expect = 3.6
Identities = 41/197 (20%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 145 RSRFFNLKLKNQ-----TSERSRVRSSNQ--LPRSNKQLFELLCYAESIDDQLNTLLKE- 196
+ + LK+KNQ +E S+ S NQ L N++L E+LC E + N+ L+E
Sbjct: 1582 KKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEK--EPGNSALEER 1639
Query: 197 ----FQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
F L EE + + + +L+ + A I N L +L+ L
Sbjct: 1640 EQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHL--LKDELEKMKQLHR 1697
Query: 253 TRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPL 312
+LS + + ++ + K + + +++ L C+D + +I +
Sbjct: 1698 CPDLSDFQQKISSVLSYNEKLLKEKEALSEE----LNSCVDKLAKSSLLEHRIATMKQEQ 1753
Query: 313 VRFSHQASGFQCDLTTN 329
+ HQ++ + L +
Sbjct: 1754 KSWEHQSASLKSQLVAS 1770
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 30.8 bits (68), Expect = 3.6
Identities = 41/197 (20%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 145 RSRFFNLKLKNQ-----TSERSRVRSSNQ--LPRSNKQLFELLCYAESIDDQLNTLLKE- 196
+ + LK+KNQ +E S+ S NQ L N++L E+LC E + N+ L+E
Sbjct: 1576 KKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEK--EPGNSALEER 1633
Query: 197 ----FQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
F L EE + + + +L+ + A I N L +L+ L
Sbjct: 1634 EQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHL--LKDELEKMKQLHR 1691
Query: 253 TRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPL 312
+LS + + ++ + K + + +++ L C+D + +I +
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEALSEE----LNSCVDKLAKSSLLEHRIATMKQEQ 1747
Query: 313 VRFSHQASGFQCDLTTN 329
+ HQ++ + L +
Sbjct: 1748 KSWEHQSASLKSQLVAS 1764
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 30.8 bits (68), Expect = 3.6
Identities = 41/197 (20%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 145 RSRFFNLKLKNQ-----TSERSRVRSSNQ--LPRSNKQLFELLCYAESIDDQLNTLLKE- 196
+ + LK+KNQ +E S+ S NQ L N++L E+LC E + N+ L+E
Sbjct: 1576 KKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEK--EPGNSALEER 1633
Query: 197 ----FQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
F L EE + + + +L+ + A I N L +L+ L
Sbjct: 1634 EQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHL--LKDELEKMKQLHR 1691
Query: 253 TRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPL 312
+LS + + ++ + K + + +++ L C+D + +I +
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEALSEE----LNSCVDKLAKSSLLEHRIATMKQEQ 1747
Query: 313 VRFSHQASGFQCDLTTN 329
+ HQ++ + L +
Sbjct: 1748 KSWEHQSASLKSQLVAS 1764
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 30.8 bits (68), Expect = 3.6
Identities = 41/197 (20%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 145 RSRFFNLKLKNQ-----TSERSRVRSSNQ--LPRSNKQLFELLCYAESIDDQLNTLLKE- 196
+ + LK+KNQ +E S+ S NQ L N++L E+LC E + N+ L+E
Sbjct: 1576 KKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEK--EPGNSALEER 1633
Query: 197 ----FQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDE 252
F L EE + + + +L+ + A I N L +L+ L
Sbjct: 1634 EQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHL--LKDELEKMKQLHR 1691
Query: 253 TRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPL 312
+LS + + ++ + K + + +++ L C+D + +I +
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEALSEE----LNSCVDKLAKSSLLEHRIATMKQEQ 1747
Query: 313 VRFSHQASGFQCDLTTN 329
+ HQ++ + L +
Sbjct: 1748 KSWEHQSASLKSQLVAS 1764
>gi|6678271 TAR DNA binding protein [Homo sapiens]
Length = 414
Score = 30.4 bits (67), Expect = 4.7
Identities = 14/64 (21%), Positives = 33/64 (51%)
Query: 64 SEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKES 123
S+ + ++++ + C E ++E++ ++ SQ+G + + F + F +A V F +
Sbjct: 180 SKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQI 239
Query: 124 IGSL 127
SL
Sbjct: 240 AQSL 243
>gi|47458825 hypothetical protein LOC144577 [Homo sapiens]
Length = 445
Score = 30.4 bits (67), Expect = 4.7
Identities = 12/31 (38%), Positives = 20/31 (64%)
Query: 438 ELLLKEFFEYFGNFAFDKNSINIRQGREQNK 468
+ +L+ FF + G F++DK N+ + RE NK
Sbjct: 15 QAVLETFFSHLGIFSYDKAKDNVEKEREANK 45
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 29.6 bits (65), Expect = 8.0
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 29/154 (18%)
Query: 455 KNSINIRQGREQNKPDSSPLY----IQNPFETSLNISKNVSQSQLQKFVDL--------A 502
+N +NIR+ RE+ ++ ++ T+L KN + + +DL A
Sbjct: 1386 ENIVNIRKQREKAAILIQAVWKGFILRKKLTTALEAIKNEESDEEYREIDLEDFIFDEAA 1445
Query: 503 RESAWI------------LQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFA 550
E W+ L P I N W S LPS P + K N +
Sbjct: 1446 LEEEWLALDSTRFPSQTLLLSNQLHWPKIPGNLKWDDTSFNLPSNPAQAWLCNDKENLSS 1505
Query: 551 IETVKNLLESLKGNRTENFT---KTSGKRTISTQ 581
E + S N+T ++T KTS K + ++
Sbjct: 1506 SEHTQ--FNSRSENKTSSWTPESKTSRKSLLKSE 1537
>gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo
sapiens]
Length = 1004
Score = 29.6 bits (65), Expect = 8.0
Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
Query: 145 RSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENT 204
RS L L Q +R+ + SS +L + L ES D++LN +L EEN
Sbjct: 220 RSLQEELYLLKQELQRANMVSSCELELQEQSL-RTASDQESGDEELN------RLKEENE 272
Query: 205 KLRYLTCSLIE 215
KLR LT SL E
Sbjct: 273 KLRSLTFSLAE 283
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,609,370
Number of Sequences: 37866
Number of extensions: 873625
Number of successful extensions: 2171
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2123
Number of HSP's gapped (non-prelim): 32
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.