Guide to the Human Genome
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Search of human proteins with 189458821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189458821 transglutaminase 3 precursor [Homo sapiens]
         (693 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189458821 transglutaminase 3 precursor [Homo sapiens]             1396   0.0  
gi|148664232 transglutaminase 6 [Homo sapiens]                        664   0.0  
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]               605   e-173
gi|16445035 transglutaminase 7 [Homo sapiens]                         525   e-149
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]                524   e-148
gi|39777597 transglutaminase 2 isoform a [Homo sapiens]               487   e-137
gi|4507475 transglutaminase 1 [Homo sapiens]                          445   e-125
gi|39777599 transglutaminase 2 isoform b [Homo sapiens]               417   e-116
gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ...   411   e-114
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]             390   e-108
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho...   332   7e-91
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho...   331   2e-90
gi|42476024 THUMP domain containing 1 [Homo sapiens]                   32   2.6  
gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens]         31   3.4  
gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens]          31   3.4  
gi|58743319 arylsulfatase family, member H [Homo sapiens]              31   4.4  
gi|38372901 Sp1 transcription factor isoform a [Homo sapiens]          30   5.8  
gi|218751903 Sp1 transcription factor isoform b [Homo sapiens]         30   5.8  
gi|148833504 interleukin 16 isoform 2 [Homo sapiens]                   30   5.8  
gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]          30   5.8  
gi|9945439 septin 5 [Homo sapiens]                                     30   5.8  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           30   5.8  
gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Hom...    30   7.5  
gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Hom...    30   7.5  
gi|18379366 zinc metallopeptidase STE24 [Homo sapiens]                 30   7.5  
gi|9256604 protocadherin beta 11 precursor [Homo sapiens]              30   7.5  
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]        30   9.8  
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]        30   9.8  
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]          30   9.8  
gi|40255119 RAS and EF-hand domain containing [Homo sapiens]           30   9.8  

>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
          Length = 693

 Score = 1396 bits (3614), Expect = 0.0
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST 60
           MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST
Sbjct: 1   MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST 60

Query: 61  GPYPSESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQ 120
           GPYPSESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQ
Sbjct: 61  GPYPSESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQ 120

Query: 121 GGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQ 180
           GGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQ
Sbjct: 121 GGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQ 180

Query: 181 FEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGT 240
           FEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGT
Sbjct: 181 FEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGT 240

Query: 241 YTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSA 300
           YTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSA
Sbjct: 241 YTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSA 300

Query: 301 HDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQER 360
           HDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQER
Sbjct: 301 HDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQER 360

Query: 361 SQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIG 420
           SQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIG
Sbjct: 361 SQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIG 420

Query: 421 RYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQE 480
           RYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQE
Sbjct: 421 RYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQE 480

Query: 481 PSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSAT 540
           PSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSAT
Sbjct: 481 PSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSAT 540

Query: 541 MSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDIILDNPTLTLE 600
           MSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDIILDNPTLTLE
Sbjct: 541 MSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDIILDNPTLTLE 600

Query: 601 VLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRFD 660
           VLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRFD
Sbjct: 601 VLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRFD 660

Query: 661 ILPSRSGTKQLLADFSCNKFPAIKAMLSIDVAE 693
           ILPSRSGTKQLLADFSCNKFPAIKAMLSIDVAE
Sbjct: 661 ILPSRSGTKQLLADFSCNKFPAIKAMLSIDVAE 693


>gi|148664232 transglutaminase 6 [Homo sapiens]
          Length = 706

 Score =  664 bits (1714), Expect = 0.0
 Identities = 354/710 (49%), Positives = 461/710 (64%), Gaps = 25/710 (3%)

Query: 1   MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST 60
           MA + V  ++WQ + N  AHHT ++   EL++RRGQ+F + + +++ L   E L F + T
Sbjct: 1   MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET 60

Query: 61  GPYPSESAMTKAVFPLSNGSSG-GWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFS 119
           GP  SE+  TKAVF  S    G GW+A  +A    TLT+S++SP SA IGRY +++++ S
Sbjct: 61  GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS 120

Query: 120 QGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFG 179
               S+ +LG F+LLFNPW   D VF+ +  ER+EYV  D+GIIF G    I   GWN+G
Sbjct: 121 HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG 180

Query: 180 QFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSG 239
           QFEEDIL+ICLSILDRS   + + ATDV+ R++P YV RV+SAM+NSN+D GV+ G W G
Sbjct: 181 QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG 240

Query: 240 TYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNS 299
            Y GG  P  W GSV IL+ W K  + PV+YGQCWVFAG L T LR LGI +RV++NFNS
Sbjct: 241 KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS 300

Query: 300 AHDTDRNLSVDVYYDPMGNPL-DKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQ 358
           AHDTD+NLSVD Y D  G  L D   DS+WNFHVWNE WF R DLGPSY GWQVLDATPQ
Sbjct: 301 AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ 360

Query: 359 ERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHT 418
           E S+GVF+CGPASV  +REGDV L  D PF+FAEVNAD ITWL+     ++   S N+  
Sbjct: 361 EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYS-NTKK 419

Query: 419 IGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSM------ 472
           IGR ISTKAVGS++R+D+TD YKYPEGS +ERQV+ KA+ +L     F   +S       
Sbjct: 420 IGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRL-----FGVEASGRRIWIR 474

Query: 473 ----------GLETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAW 522
                      L     +PSI GK KV     +G ++ L L L NL+   + V VN++  
Sbjct: 475 RAGGRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGA 534

Query: 523 TIIYNGTLVHEVWKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES 582
           TI+Y    V E+  +S  + L P+EE   PI ISY++Y++ L  D  I + A+C V    
Sbjct: 535 TILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGE 594

Query: 583 EVVVERDIILDNPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNL 642
           +++VE+DI L++  +T++VL  A V   V V++   NPL E V+DC LMVEGSGLL   L
Sbjct: 595 KLLVEKDITLED-FITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQL 653

Query: 643 KIDVPTLGPKEGSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDVA 692
            IDVPTL P+E + V+FDI PS+SG +QL  D     FP IK  + + VA
Sbjct: 654 SIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVA 703


>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
          Length = 720

 Score =  605 bits (1560), Expect = e-173
 Identities = 318/714 (44%), Positives = 451/714 (63%), Gaps = 28/714 (3%)

Query: 4   LGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQV-LMIMNKGLGSN-ERLEFIVSTG 61
           L V   + Q++ N   HHT++ +   L++RRGQ F + L   N+      + + F+V TG
Sbjct: 5   LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETG 64

Query: 62  PYPSESAMTKAVFPLS-NGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFS- 119
           P P  +  T+AVF L+ + S   W A L+ +   +  +S+ +P +A +GRY + + I S 
Sbjct: 65  PLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSF 124

Query: 120 QGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFG 179
           QG +++ +LG FILLFNPW   D+V++ +  +R+EYV  D G I+ GS N I    WN+G
Sbjct: 125 QGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYG 184

Query: 180 QFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSG 239
           QFE+ I+ ICL +LD+SL+F+ D ATD A R  P YV RV+ AMINSNDDNGVL GNWS 
Sbjct: 185 QFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSE 244

Query: 240 TYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNS 299
            YT G +P  W GSV ILK W  +G  PVRYGQCWVFA  + T +R LGIP+RVITNF+S
Sbjct: 245 NYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDS 304

Query: 300 AHDTDRNLSVDVYYDPMGNPL-DKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQ 358
            HDTD NL +D YYD  G  L +K  D++WNFHVWNE W  R DL P+YGGWQVLDATPQ
Sbjct: 305 GHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQ 364

Query: 359 ERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHT 418
           E S GV+ CGPASV  ++EG+V LN+D PF+F+ VNAD ++WL     GK+ K   ++ +
Sbjct: 365 EMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQG--GKEQKLHQDTSS 422

Query: 419 IGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPN--------------- 463
           +G +ISTK++ S+ R D+T+ YKY EGS QERQVF KAL KLK                 
Sbjct: 423 VGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSR 482

Query: 464 -TPFAATSSMGLETEEQEPS----IIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVN 518
            T  +  S   L T    PS    +  K K+     +G+++  VLL  N+S   K + VN
Sbjct: 483 PTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVN 542

Query: 519 MTAWTIIYNGTLVHEVWKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKV 578
           ++A +++++G+ +   W+D+A ++L P+E   +P KISY+QY +YL +D +IRI+A+ + 
Sbjct: 543 LSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEE 602

Query: 579 PDESE-VVVERDIILDNPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGL 637
               E ++V + I L  P++T+ VL  A V +P+++Q++FSNPL E V DCVL VEGSGL
Sbjct: 603 KSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGL 662

Query: 638 LLGNLKIDVPTLGPKEGSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
                K+ +  L P+  + +  + +P +SG +Q+ A+   NKF  IK   ++ V
Sbjct: 663 FKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 716


>gi|16445035 transglutaminase 7 [Homo sapiens]
          Length = 710

 Score =  525 bits (1351), Expect = e-149
 Identities = 283/706 (40%), Positives = 418/706 (59%), Gaps = 20/706 (2%)

Query: 1   MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGS-NERLEFIVS 59
           +A L ++S++ Q++ N + HHT +   + L +RRGQ F + +  ++   S N+ + F+  
Sbjct: 4   VATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITFVAE 63

Query: 60  TGPYPSESAMTKAVFPLSNGSSGG-WSAVLQASNGNTLTISISSPASAPIGRYTMALQIF 118
           TGP PSE   T+A F L+    G  WSA     + N+L +S+ +PA+A IG YT+ ++I 
Sbjct: 64  TGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEIS 123

Query: 119 S-QGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWN 177
             QG   +  LGTFILLFNPW   D V++ +    +EY+  D G ++ G    I    WN
Sbjct: 124 QGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWPWN 183

Query: 178 FGQFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNW 237
           +GQFEEDI+ IC  IL++SL   ++ A D + RND  YV RV+SAMINSNDDNGVL GNW
Sbjct: 184 YGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQGNW 243

Query: 238 SGTYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNF 297
              Y+ G  P  W GSV IL+ W   G  PV+YGQCWVFA  + T +R LG+P+RV++NF
Sbjct: 244 GEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVSNF 303

Query: 298 NSAHDTDRNLSVDVYYDPMGNPLD-KGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDAT 356
            SAH+ DRNL++D YYD     L  +  D +WNFHVWNE W +R DL P Y GWQVLD T
Sbjct: 304 RSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVLDPT 363

Query: 357 PQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNS 416
           PQ+ S G+F CGPASV  +REGDV L +D PF++AEVNAD + WL  +   ++   + N+
Sbjct: 364 PQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEIL-AHNT 422

Query: 417 HTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKA----LGKLKPNTPFA-ATSS 471
            +IG+ ISTK VGS+ R  +T  YKYPEGS +ER VF KA    LG  + + PF     S
Sbjct: 423 SSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLLES 482

Query: 472 MGLETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKT-----VTVNMTAWTIIY 526
            GL  +  +     +L +A +   G+++ L+L ++ +   T       + V   A  +++
Sbjct: 483 GGLRDQPAQL----QLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLH 538

Query: 527 NGTLVHEVWKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES-EVV 585
            G      W+ +  M+LD  +E + P+ + Y+ Y   L  + +IR++ + +V +    ++
Sbjct: 539 GGGTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSML 598

Query: 586 VERDIILDNPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKID 645
           V +DI L+ P L++EV   A V K + V +  +N L   +  C +++EGSGL+ G +  D
Sbjct: 599 VLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKD 658

Query: 646 VPTLGPKEGSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
           + TL      +++ D+ P+++G +QL    S N+   IK    I V
Sbjct: 659 LGTLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFV 704


>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
          Length = 638

 Score =  524 bits (1349), Expect = e-148
 Identities = 268/572 (46%), Positives = 370/572 (64%), Gaps = 24/572 (4%)

Query: 142 DSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFEEDILSICLSILDRSLNFRR 201
           D+V++ +  +R+EYV  D G I+ GS N I    WN+GQFE+ I+ ICL +LD+SL+F+ 
Sbjct: 65  DAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQT 124

Query: 202 DAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYTGGRDPRSWNGSVEILKNWK 261
           D ATD A R  P YV RV+ AMINSNDDNGVL GNWS  YT G +P  W GSV ILK W 
Sbjct: 125 DPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWN 184

Query: 262 KSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHDTDRNLSVDVYYDPMGNPL- 320
            +G  PVRYGQCWVFA  + T +R LGIP+RVITNF+S HDTD NL +D YYD  G  L 
Sbjct: 185 ATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILG 244

Query: 321 DKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASVIGVREGDV 380
           +K  D++WNFHVWNE W  R DL P+YGGWQVLDATPQE S GV+ CGPASV  ++EG+V
Sbjct: 245 NKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEV 304

Query: 381 QLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNARMDVTDKY 440
            LN+D PF+F+ VNAD ++WL     GK+ K   ++ ++G +ISTK++ S+ R D+T+ Y
Sbjct: 305 DLNYDTPFVFSMVNADCMSWLVQG--GKEQKLHQDTSSVGNFISTKSIQSDERDDITENY 362

Query: 441 KYPEGSDQERQVFQKALGKLKPN----------------TPFAATSSMGLETEEQEPS-- 482
           KY EGS QERQVF KAL KLK                  T  +  S   L T    PS  
Sbjct: 363 KYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDV 422

Query: 483 --IIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSAT 540
             +  K K+     +G+++  VLL  N+S   K + VN++A +++++G+ +   W+D+A 
Sbjct: 423 VQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAF 482

Query: 541 MSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESE-VVVERDIILDNPTLTL 599
           ++L P+E   +P KISY+QY +YL +D +IRI+A+ +     E ++V + I L  P++T+
Sbjct: 483 ITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITI 542

Query: 600 EVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRF 659
            VL  A V +P+++Q++FSNPL E V DCVL VEGSGL     K+ +  L P+  + +  
Sbjct: 543 NVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIIL 602

Query: 660 DILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
           + +P +SG +Q+ A+   NKF  IK   ++ V
Sbjct: 603 ETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 4  LGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQV-LMIMNKGLGSN-ERLEFIVST 60
          L V   + Q++ N   HHT++ +   L++RRGQ F + L   N+      + + F+V T
Sbjct: 5  LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVET 63


>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
          Length = 687

 Score =  487 bits (1254), Expect = e-137
 Identities = 264/682 (38%), Positives = 387/682 (56%), Gaps = 24/682 (3%)

Query: 16  NRQAHHTDKFSSQELILRRGQNFQVLMIMN--KGLGSNERLEFIVSTGPYPSESAMTKAV 73
           N + HHT     ++L++RRGQ F + +         S + L F V TGP PS+ A TKA 
Sbjct: 17  NGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKAR 76

Query: 74  FPLSNG-SSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFI 132
           FPL +    G W+A +      TL++ +++PA+APIG Y ++L+  +    SS  LG FI
Sbjct: 77  FPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFI 136

Query: 133 LLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFEEDILSICLSI 192
           LLFN W   D+V++ +  ER+EYV    G I+ GS   I  I WNFGQFE+ IL ICL +
Sbjct: 137 LLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLIL 196

Query: 193 LDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYTGGRDPRSWNG 252
           LD +  F ++A  D + R+ P YVGRV+S M+N NDD GVL G W   Y  G  P SW G
Sbjct: 197 LDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIG 256

Query: 253 SVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHDTDRNLSVDVY 312
           SV+IL+ WK  G   V+YGQCWVFA    T LR LGIP+RV+TN+NSAHD + NL ++ +
Sbjct: 257 SVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYF 316

Query: 313 YDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASV 372
            +  G      S+ +WNFH W E W  R DL P Y GWQ LD TPQE+S+G + CGP  V
Sbjct: 317 RNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPV 376

Query: 373 IGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNA 432
             ++EGD+   +D PF+FAEVNAD + W+  +  G   K+   S  +G  ISTK+VG + 
Sbjct: 377 RAIKEGDLSTKYDAPFVFAEVNADVVDWIQQD-DGSVHKSINRSLIVGLKISTKSVGRDE 435

Query: 433 RMDVTDKYKYPEGSDQERQVFQKA--LGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVA 490
           R D+T  YKYPEGS +ER+ F +A  L KL                E++E  +  +++V 
Sbjct: 436 REDITHTYKYPEGSSEEREAFTRANHLNKL---------------AEKEETGMAMRIRVG 480

Query: 491 GMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEV-WKDSATMSLDPEEEA 549
             + +G + ++   + N + +     + + A T+ YNG L  E   K    ++L+P  E 
Sbjct: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 540

Query: 550 EHPIKISYAQYEKYLKSDNMIRITAVCKVP-DESEVVVERDIILDNPTLTLEVLNEARVR 608
             P+ I Y +Y   L   N+I++ A+   P   S ++ ERD+ L+NP + + +L E + +
Sbjct: 541 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 600

Query: 609 KPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVP-TLGPKEGSRVRFDILPSRSG 667
           + +  ++   NPL   +  C   VEG+GL      +++P  +   E  +VR D+LP   G
Sbjct: 601 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 660

Query: 668 TKQLLADFSCNKFPAIKAMLSI 689
             +L+ +F  +K  A+K   ++
Sbjct: 661 LHKLVVNFESDKLKAVKGFRNV 682


>gi|4507475 transglutaminase 1 [Homo sapiens]
          Length = 817

 Score =  445 bits (1144), Expect = e-125
 Identities = 253/699 (36%), Positives = 387/699 (55%), Gaps = 36/699 (5%)

Query: 5   GVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVSTGPYP 64
           GV  ++ ++  NR+ HHTD++   ELI+RRGQ F +L+++++   S++R+   +  G  P
Sbjct: 114 GVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNP 173

Query: 65  SESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGIS 124
                T  + P+  G SGGW A +  ++G  L + + +  +A IG++   ++  S  G  
Sbjct: 174 EVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEF 233

Query: 125 SVKL---GTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQF 181
            +         +LFNPW   D V++ +   R+EYV  ++G I+ G+  +IG   WN+GQF
Sbjct: 234 QLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQF 293

Query: 182 EEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTY 241
           +  +L  CL ILDR              R DP  V RV+SAM+NS DDNGVL GNWSG Y
Sbjct: 294 DHGVLDACLYILDRR-------GMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDY 346

Query: 242 TGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAH 301
           + G +P +W GSVEIL ++ ++G+S V YGQCWVFAG   T LR LG+ +R +TNFNSAH
Sbjct: 347 SRGTNPSAWVGSVEILLSYLRTGYS-VPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAH 405

Query: 302 DTDRNLSVDVYYDPMGNPLDK-GSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQER 360
           DTD +L++D+Y+D    PL+    DSVWNFHVWN+ W  R DL   + GWQV+DATPQE 
Sbjct: 406 DTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQET 465

Query: 361 SQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIG 420
           S G+F CGP SV  ++ G V + +D PFIFAEVN+D++ W   +  G      V    IG
Sbjct: 466 SSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQD-DGSFKIVYVEEKAIG 524

Query: 421 RYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGK-LKPN--TPFAATSSMGLETE 477
             I TKA+ SN R D+T  YK+PEGSD ER+  + A     KPN      +   + ++ E
Sbjct: 525 TLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVE 584

Query: 478 EQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIY---NGTLVHEV 534
            Q+              +G+++ + ++L N S   +TV +++      Y   +GT+  E 
Sbjct: 585 AQD------------AVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKET 632

Query: 535 WKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDII-LD 593
            K+   + L P       + ++Y +Y  +L     + +     V +  +V+ ++    L 
Sbjct: 633 KKE---VELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLR 689

Query: 594 NPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKE 653
            P L+L +L  A V +   VQ++F NPL   + + V  +EGSGL    + ++V  +G  E
Sbjct: 690 TPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKI-LNVGDIGGNE 748

Query: 654 GSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDVA 692
              +R   +P R G +QL+A     +   +  ++ +DVA
Sbjct: 749 TVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVA 787


>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
          Length = 548

 Score =  417 bits (1072), Expect = e-116
 Identities = 219/520 (42%), Positives = 305/520 (58%), Gaps = 21/520 (4%)

Query: 16  NRQAHHTDKFSSQELILRRGQNFQVLMIMN--KGLGSNERLEFIVSTGPYPSESAMTKAV 73
           N + HHT     ++L++RRGQ F + +         S + L F V TGP PS+ A TKA 
Sbjct: 17  NGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKAR 76

Query: 74  FPLSNG-SSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFI 132
           FPL +    G W+A +      TL++ +++PA+APIG Y ++L+  +    SS  LG FI
Sbjct: 77  FPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFI 136

Query: 133 LLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFEEDILSICLSI 192
           LLFN W   D+V++ +  ER+EYV    G I+ GS   I  I WNFGQFE+ IL ICL +
Sbjct: 137 LLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLIL 196

Query: 193 LDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYTGGRDPRSWNG 252
           LD +  F ++A  D + R+ P YVGRV+S M+N NDD GVL G W   Y  G  P SW G
Sbjct: 197 LDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIG 256

Query: 253 SVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHDTDRNLSVDVY 312
           SV+IL+ WK  G   V+YGQCWVFA    T LR LGIP+RV+TN+NSAHD + NL ++ +
Sbjct: 257 SVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYF 316

Query: 313 YDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASV 372
            +  G      S+ +WNFH W E W  R DL P Y GWQ LD TPQE+S+G + CGP  V
Sbjct: 317 RNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPV 376

Query: 373 IGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNA 432
             ++EGD+   +D PF+FAEVNAD + W+  +  G   K+   S  +G  ISTK+VG + 
Sbjct: 377 RAIKEGDLSTKYDAPFVFAEVNADVVDWIQQD-DGSVHKSINRSLIVGLKISTKSVGRDE 435

Query: 433 RMDVTDKYKYPEGSDQERQVFQKA--LGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVA 490
           R D+T  YKYPEGS +ER+ F +A  L KL                E++E  +  +++V 
Sbjct: 436 REDITHTYKYPEGSSEEREAFTRANHLNKL---------------AEKEETGMAMRIRVG 480

Query: 491 GMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTL 530
             + +G + ++   + N + +     + + A T+ YNG L
Sbjct: 481 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGIL 520


>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
           sapiens]
          Length = 732

 Score =  411 bits (1056), Expect = e-114
 Identities = 240/694 (34%), Positives = 375/694 (54%), Gaps = 38/694 (5%)

Query: 11  WQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNE---RLEFIVSTGPYPSES 67
           W T  N+  HHTDK+ + +LI+RRGQ+F V +  ++         R+E+++  G YP E+
Sbjct: 58  WDT--NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVI--GRYPQEN 113

Query: 68  AMTKAVFPL-SNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGI--- 123
             T    P+ S   SG W A +      ++ +SI S     +G++ M + +++  G+   
Sbjct: 114 KGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRT 173

Query: 124 -SSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFE 182
             + +  T+IL FNPW   D+V++ N  EREEYV  D G+IF G  N I    W++GQFE
Sbjct: 174 SRNPETDTYIL-FNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFE 232

Query: 183 EDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYT 242
           + IL  CL ++DR       A  D++ R +P  V RV SAM+N+ DD GVL G+W   Y 
Sbjct: 233 DGILDTCLYVMDR-------AQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYA 285

Query: 243 GGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHD 302
            G  P +W GSV+IL  ++ S  +PVRYGQCWVFAG  NT LR LGIP+R++TN+ SAHD
Sbjct: 286 YGVPPSAWTGSVDILLEYRSSE-NPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHD 344

Query: 303 TDRNLSVDVYYDPMGNPLDK-GSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERS 361
            D NL +D++ +  GN   K   DSVWN+H WNE W  R DL   +GGWQ +D+TPQE S
Sbjct: 345 NDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENS 404

Query: 362 QGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGR 421
            G+++CGPASV  ++ G V   FD PF+FAEVN+D I ++     G     +V++  IG+
Sbjct: 405 DGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLI-YITAKKDGTHVVENVDATHIGK 463

Query: 422 YISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKAL--GKLKP-NTPFAATSSMGLETEE 478
            I TK +G +  MD+TD YK+ EG ++ER   + AL  G  KP NT     S   ++ + 
Sbjct: 464 LIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDF 523

Query: 479 QEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDS 538
           +  + +          +GK+  L +  +N S +  T+T  ++A    Y G    E  K++
Sbjct: 524 EVENAV----------LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKET 573

Query: 539 ATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVV-ERDIILDNPTL 597
             ++L+P    +  + I   +Y   L     +      ++ +  +V+  ++  +L  P +
Sbjct: 574 FDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEI 633

Query: 598 TLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRV 657
            ++V     V   + V + F+NPL E +R+  + ++G G+     K+    + P    + 
Sbjct: 634 IIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKM-FREIRPNSTVQW 692

Query: 658 RFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
                P  SG ++L+A  S +    +   L + +
Sbjct: 693 EEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726


>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
          Length = 684

 Score =  390 bits (1001), Expect = e-108
 Identities = 236/691 (34%), Positives = 364/691 (52%), Gaps = 31/691 (4%)

Query: 4   LGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVSTGPY 63
           L V  I++    N  +HHT +F +   + RRGQ F + +++N+ L S  +L+   STGP 
Sbjct: 8   LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPN 67

Query: 64  PSESAMTKAVF-PLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGG 122
           PS +  T  V  P +      W A LQ  +G  +T++++S  +A +G+Y   L + +   
Sbjct: 68  PSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQ--LNVKTGNH 125

Query: 123 ISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFE 182
           I   +     LLFNPW   D VFM +  ER+EY+  D G  +VG+   I    WNFGQFE
Sbjct: 126 ILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFE 185

Query: 183 EDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYT 242
           +++L  C+S+L  S       +     R DP  V R + AM++     GVL GNW+G Y 
Sbjct: 186 KNVLDCCISLLTES-------SLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYE 238

Query: 243 GGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHD 302
           GG  P  W GS  IL+ +  +    V +GQCWVFAG L T LR+LGIP+R +T F+SAHD
Sbjct: 239 GGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHD 297

Query: 303 TDRNLSVDVYYDPMGNPLDKGS-DSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERS 361
           T+RNL+VD Y +  G  +   + DSVWNFHVW + W  R DL   Y GWQ +DATPQERS
Sbjct: 298 TERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERS 357

Query: 362 QGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHT--I 419
           QGVF CGP+ +  +R+GD+ + +D  F+F+EVN DR+ WL     G++  + ++  T  I
Sbjct: 358 QGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSI 417

Query: 420 GRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQ 479
           G+ ISTKAVG + R D+T +YKYPEGS +ERQV   A         F   SS        
Sbjct: 418 GKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHA---------FLLLSSEREHRRPV 468

Query: 480 EPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSA 539
           + + +     +  + +G  VN  ++LK  +   + V +  +    +Y G  + ++   + 
Sbjct: 469 KENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNK 528

Query: 540 TMSLDPEEEAEHPIKI---SYAQYEKYLKSDNMIRITAVCKVPDESEVVV-ERDIILDNP 595
           T  +   + +E  + +   +Y      L  + +IR   + ++ +  E++  E       P
Sbjct: 529 TSQIQ-GQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYP 587

Query: 596 TLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKI-DVPTLGPKEG 654
             ++E+ N  R+ + +    +F N L  P+ D    +E  G  + +L+  D  T+ P E 
Sbjct: 588 EFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLG--ISSLQTSDHGTVQPGET 645

Query: 655 SRVRFDILPSRSGTKQLLADFSCNKFPAIKA 685
            + +    P ++G K+ +   S  +   I A
Sbjct: 646 IQSQIKCTPIKTGPKKFIVKLSSKQVKEINA 676


>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
           sapiens]
          Length = 721

 Score =  332 bits (851), Expect = 7e-91
 Identities = 212/698 (30%), Positives = 337/698 (48%), Gaps = 22/698 (3%)

Query: 1   MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKG----LGSNERLEF 56
           M ALG++S ++Q A N + HHT   SS+ L +RRGQ F +++         L + +++  
Sbjct: 32  MDALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVAL 91

Query: 57  IVSTGPYPSESAMTKAVFPLSN-GSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMAL 115
              TG  PS+   T+A FP+S+ G    WSAV++  +  + TIS+++PA A IG Y++ L
Sbjct: 92  TAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLL 151

Query: 116 QIFSQGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIG 175
           Q+    G   + LG F LLFNPW   D+VF+ N A+R EY+    G+I++G+ + I    
Sbjct: 152 QV---SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAES 208

Query: 176 WNFGQFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAG 235
           W+FGQFE D++ + L +L +           V   + P +V RVL A+++   +  VL  
Sbjct: 209 WDFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPT 260

Query: 236 NWSGTYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVIT 295
             +     G       GSV IL+ W      PV  GQ WV A    T LR LGIP+RV+T
Sbjct: 261 PQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVT 320

Query: 296 NFNSAHDTDRNLSVDVYYDPMGNPLDKGS-DSVWNFHVWNEGWFVRSDLGPSYGGWQVLD 354
            F SA  T   L +D YY+  G    +G    +W F    E W  R  L   Y GWQ+L 
Sbjct: 321 TFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILH 380

Query: 355 ATPQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSV 414
            +       +  C    V  V+EG + L   +  +FA +NA  + W        +  +S 
Sbjct: 381 PSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDS- 439

Query: 415 NSHTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGL 474
           N+  +G  ISTK VGS+   D+T  YKYPEGS QE++V ++   +              L
Sbjct: 440 NTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSL 499

Query: 475 ETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEV 534
           ET      +   LK    L +  +  + + L N S   K V + +    + YNG L  ++
Sbjct: 500 ETAS---PLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKL 556

Query: 535 WKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES-EVVVERDIILD 593
           W+    ++L    E    I + ++ +E+    +  +R+TA+    + +     + DI + 
Sbjct: 557 WRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAIC 616

Query: 594 NPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKE 653
            P L +++  +A   +P+   +   N LD P+ DCV+ + G GL+         ++ P+ 
Sbjct: 617 RPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPEN 676

Query: 654 GSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
               +F   P+  G ++L  +  CN F  +    S+ V
Sbjct: 677 TMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714


>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
           sapiens]
          Length = 691

 Score =  331 bits (848), Expect = 2e-90
 Identities = 211/696 (30%), Positives = 336/696 (48%), Gaps = 22/696 (3%)

Query: 3   ALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKG----LGSNERLEFIV 58
           ALG++S ++Q A N + HHT   SS+ L +RRGQ F +++         L + +++    
Sbjct: 4   ALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTA 63

Query: 59  STGPYPSESAMTKAVFPLSN-GSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQI 117
            TG  PS+   T+A FP+S+ G    WSAV++  +  + TIS+++PA A IG Y++ LQ+
Sbjct: 64  QTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQV 123

Query: 118 FSQGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWN 177
               G   + LG F LLFNPW   D+VF+ N A+R EY+    G+I++G+ + I    W+
Sbjct: 124 ---SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWD 180

Query: 178 FGQFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNW 237
           FGQFE D++ + L +L +           V   + P +V RVL A+++   +  VL    
Sbjct: 181 FGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQ 232

Query: 238 SGTYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNF 297
           +     G       GSV IL+ W      PV  GQ WV A    T LR LGIP+RV+T F
Sbjct: 233 TQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTF 292

Query: 298 NSAHDTDRNLSVDVYYDPMGNPLDKGS-DSVWNFHVWNEGWFVRSDLGPSYGGWQVLDAT 356
            SA  T   L +D YY+  G    +G    +W F    E W  R  L   Y GWQ+L  +
Sbjct: 293 ASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPS 352

Query: 357 PQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNS 416
                  +  C    V  V+EG + L   +  +FA +NA  + W        +  +S N+
Sbjct: 353 APNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDS-NT 411

Query: 417 HTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLET 476
             +G  ISTK VGS+   D+T  YKYPEGS QE++V ++   +              LET
Sbjct: 412 KYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLET 471

Query: 477 EEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWK 536
                 +   LK    L +  +  + + L N S   K V + +    + YNG L  ++W+
Sbjct: 472 AS---PLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWR 528

Query: 537 DSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES-EVVVERDIILDNP 595
               ++L    E    I + ++ +E+    +  +R+TA+    + +     + DI +  P
Sbjct: 529 KKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRP 588

Query: 596 TLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGS 655
            L +++  +A   +P+   +   N LD P+ DCV+ + G GL+         ++ P+   
Sbjct: 589 HLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTM 648

Query: 656 RVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
             +F   P+  G ++L  +  CN F  +    S+ V
Sbjct: 649 CAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 684


>gi|42476024 THUMP domain containing 1 [Homo sapiens]
          Length = 353

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 18/106 (16%)

Query: 129 GTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGII-FVGSTNRIGMIGWNFGQFEEDILS 187
           GTF +++    N       +H  REE ++E AGI+  + S N++ +    +    E I +
Sbjct: 194 GTFQIVYKSRNN-------SHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKA 246

Query: 188 I-CLSILDRSLNFRRDAATDVA-SRNDPKYVGRVLSAMINSNDDNG 231
           + CLS++   + FR+    +V  S  DP        + +NS   NG
Sbjct: 247 VCCLSVVKDYMLFRKYNLQEVVKSPKDP--------SQLNSKQGNG 284


>gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens]
          Length = 410

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 504 LLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSA---TMSLDPEEEAEHPIKIS 556
           L+    R  +++ + M  +T  Y GT+   +WKDS    ++  +P +E++ P K+S
Sbjct: 43  LVSREQRFYESLPLAMKRFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVS 98


>gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens]
          Length = 410

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 504 LLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSA---TMSLDPEEEAEHPIKIS 556
           L+    R  +++ + M  +T  Y GT+   +WKDS    ++  +P +E++ P K+S
Sbjct: 43  LVSREQRFYESLPLAMKRFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVS 98


>gi|58743319 arylsulfatase family, member H [Homo sapiens]
          Length = 562

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 10/28 (35%), Positives = 14/28 (50%)

Query: 229 DNGVLAGNWSGTYTGGRDPRSWNGSVEI 256
           D  V  G W+G Y GG+    W G + +
Sbjct: 332 DGAVQLGGWNGIYKGGKGMGGWEGGIRV 359


>gi|38372901 Sp1 transcription factor isoform a [Homo sapiens]
          Length = 785

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 25  FSSQELILRRGQNFQVLMIMNKG--------LGSNERLEFI---VSTGPYPSESAMTKAV 73
           F++Q +     QN Q+  + N G        +G N ++ +    +      +  A T  +
Sbjct: 425 FTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITL 484

Query: 74  FPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTM-ALQIFSQGGISSVKL 128
            P+   S G      Q S+ NT    I+S AS P G  T+ A Q+ S  G+ ++ L
Sbjct: 485 APMQGVSLG------QTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINL 534


>gi|218751903 Sp1 transcription factor isoform b [Homo sapiens]
          Length = 778

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 25  FSSQELILRRGQNFQVLMIMNKG--------LGSNERLEFI---VSTGPYPSESAMTKAV 73
           F++Q +     QN Q+  + N G        +G N ++ +    +      +  A T  +
Sbjct: 418 FTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITL 477

Query: 74  FPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTM-ALQIFSQGGISSVKL 128
            P+   S G      Q S+ NT    I+S AS P G  T+ A Q+ S  G+ ++ L
Sbjct: 478 APMQGVSLG------QTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINL 527


>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
          Length = 1332

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 19/162 (11%)

Query: 26   SSQELILRRGQNFQVLMIMNKGLGSNERLEF--IVSTGPYPSESA-----MTKAVFPLSN 78
            +SQE  +++G   +VL I  K L      +   I+     P ++      +T    P  N
Sbjct: 1150 ASQEGTIQKGN--EVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLN 1207

Query: 79   GSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFILLFNPW 138
             S+   ++   AS+     +S+ S A A +   T+ L+  S G   S++ G   L  +  
Sbjct: 1208 SSTDSAASASAASD-----VSVESTAEATV--CTVTLEKMSAGLGFSLEGGKGSLHGDKP 1260

Query: 139  LNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMI---GWN 177
            L ++ +F G  +E+ E VQ    I+ +G T   G+     WN
Sbjct: 1261 LTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWN 1302


>gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]
          Length = 631

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 19/162 (11%)

Query: 26  SSQELILRRGQNFQVLMIMNKGLGSNERLEF--IVSTGPYPSESA-----MTKAVFPLSN 78
           +SQE  +++G   +VL I  K L      +   I+     P ++      +T    P  N
Sbjct: 449 ASQEGTIQKGN--EVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLN 506

Query: 79  GSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFILLFNPW 138
            S+   ++   AS+     +S+ S A A +   T+ L+  S G   S++ G   L  +  
Sbjct: 507 SSTDSAASASAASD-----VSVESTAEATV--CTVTLEKMSAGLGFSLEGGKGSLHGDKP 559

Query: 139 LNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMI---GWN 177
           L ++ +F G  +E+ E VQ    I+ +G T   G+     WN
Sbjct: 560 LTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWN 601


>gi|9945439 septin 5 [Homo sapiens]
          Length = 369

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 27/120 (22%), Positives = 53/120 (44%), Gaps = 12/120 (10%)

Query: 440 YKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVAGMLAVGKEV 499
           Y++PE    E + F++   +LK + PFA   S     E +   + G+L   G++ V  + 
Sbjct: 218 YQFPECDSDEDEDFKQQDRELKESAPFAVIGS-NTVVEAKGQRVRGRLYPWGIVEVENQA 276

Query: 500 NL------VLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSATMSLDPEEEAEHPI 553
           +        +L++    D K VT +     + Y     H + + ++ ++ D   E+  PI
Sbjct: 277 HCDFVKLRNMLIRTHMHDLKDVTCD-----VHYENYRAHCIQQMTSKLTQDSRMESPIPI 331


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 23   DKFSSQELILRRGQNFQVLMIMNKGLGSNERLEF---IVSTGP 62
            +KF SQ L+ +  Q+ Q L ++ +G G   RLEF   ++  GP
Sbjct: 1792 EKFYSQTLVFQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGP 1834


>gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 1800

 Score = 30.0 bits (66), Expect = 7.5
 Identities = 14/39 (35%), Positives = 24/39 (61%)

Query: 77  SNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMAL 115
           SN S  G S  +Q ++ +T T + S+P S+P+GR+   +
Sbjct: 837 SNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGRWRFCI 875


>gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 1743

 Score = 30.0 bits (66), Expect = 7.5
 Identities = 14/39 (35%), Positives = 24/39 (61%)

Query: 77  SNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMAL 115
           SN S  G S  +Q ++ +T T + S+P S+P+GR+   +
Sbjct: 837 SNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGRWRFCI 875


>gi|18379366 zinc metallopeptidase STE24 [Homo sapiens]
          Length = 475

 Score = 30.0 bits (66), Expect = 7.5
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 6/55 (10%)

Query: 184 DILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDN-GVLAGNW 237
           ++LS CL++L R   F+ DA      +    Y     SA+I  N DN G    +W
Sbjct: 401 EVLSFCLTVLSRRFEFQADAFAKKLGKAKDLY-----SALIKLNKDNLGFPVSDW 450


>gi|9256604 protocadherin beta 11 precursor [Homo sapiens]
          Length = 797

 Score = 30.0 bits (66), Expect = 7.5
 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 585 VVERDIILDNPTLTLEVLNEARVR-----KPV--NVQMLFSNPLDEPVRDCVLMVEGSGL 637
           V+   +++ NPT  L++  E +VR      P+    QML   P + PV    L+     L
Sbjct: 103 VLHLQVLMQNPTQFLQI--ELQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESAKDL 160

Query: 638 LLGNLKIDVPTLGPKEGSRVRFDILPSRSGTKQLLAD--FSCNKFPAIKAMLS 688
            +G   +   T+ P     ++  ++P      +L+ D      + P +  +LS
Sbjct: 161 DVGINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKALDYEELPELSFILS 213


>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score = 29.6 bits (65), Expect = 9.8
 Identities = 16/75 (21%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 351 QVLDATPQERSQGVFQCGPASVIGVREGD-VQLNFDMPFIFAEVNADRITWLYDNTTGKQ 409
           ++L+A     ++ V++C P  VI   EG+ V+L+  +P   ++ +   I +   +  G +
Sbjct: 690 EILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNE 749

Query: 410 WKNSVNSHTIGRYIS 424
            K  V+      +++
Sbjct: 750 IKECVHGRPFFHHLT 764


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score = 29.6 bits (65), Expect = 9.8
 Identities = 16/75 (21%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 351 QVLDATPQERSQGVFQCGPASVIGVREGD-VQLNFDMPFIFAEVNADRITWLYDNTTGKQ 409
           ++L+A     ++ V++C P  VI   EG+ V+L+  +P   ++ +   I +   +  G +
Sbjct: 813 EILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNE 872

Query: 410 WKNSVNSHTIGRYIS 424
            K  V+      +++
Sbjct: 873 IKECVHGRPFFHHLT 887


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score = 29.6 bits (65), Expect = 9.8
 Identities = 16/75 (21%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 351 QVLDATPQERSQGVFQCGPASVIGVREGD-VQLNFDMPFIFAEVNADRITWLYDNTTGKQ 409
           ++L+A     ++ V++C P  VI   EG+ V+L+  +P   ++ +   I +   +  G +
Sbjct: 852 EILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNE 911

Query: 410 WKNSVNSHTIGRYIS 424
            K  V+      +++
Sbjct: 912 IKECVHGRPFFHHLT 926


>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
          Length = 740

 Score = 29.6 bits (65), Expect = 9.8
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 11/99 (11%)

Query: 443 PEGSDQERQVF---QKALGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVAGMLAVGKEV 499
           P+GS  E  +    +K +  L P T     ++    +++       K+ +AG  AVGK  
Sbjct: 502 PQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQKAY-----KIVLAGDAAVGKSS 556

Query: 500 NLVLLLKNLSRD--TKTVTVNMTAWTIIYNG-TLVHEVW 535
            L+ L KN  R+  + T+ V+    T+I +G   V ++W
Sbjct: 557 FLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLW 595


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,489,968
Number of Sequences: 37866
Number of extensions: 1143102
Number of successful extensions: 2519
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2428
Number of HSP's gapped (non-prelim): 35
length of query: 693
length of database: 18,247,518
effective HSP length: 109
effective length of query: 584
effective length of database: 14,120,124
effective search space: 8246152416
effective search space used: 8246152416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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