Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 188497705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497705 BRCA1 associated protein [Homo sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497705 BRCA1 associated protein [Homo sapiens] 1196 0.0
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 70 7e-12
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 70 7e-12
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 70 7e-12
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 59 1e-08
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens] 59 1e-08
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens] 59 1e-08
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 54 4e-07
gi|13128864 histone deacetylase 6 [Homo sapiens] 51 3e-06
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 50 6e-06
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 50 6e-06
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 50 6e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 50 8e-06
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 49 1e-05
gi|194353964 coiled-coil domain containing 157 [Homo sapiens] 49 1e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 1e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 48 2e-05
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 48 3e-05
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 48 3e-05
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 48 3e-05
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 48 3e-05
gi|55956899 keratin 9 [Homo sapiens] 47 4e-05
gi|4503593 epidermal growth factor receptor pathway substrate 15... 47 6e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 46 1e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 46 1e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 45 2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 45 2e-04
gi|55770834 centromere protein F [Homo sapiens] 45 2e-04
>gi|188497705 BRCA1 associated protein [Homo sapiens]
Length = 592
Score = 1196 bits (3094), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII 60
MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII
Sbjct: 1 MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII 60
Query: 61 HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK 120
HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK
Sbjct: 61 HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK 120
Query: 121 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF 180
QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF
Sbjct: 121 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF 180
Query: 181 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE 240
VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE
Sbjct: 181 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE 240
Query: 241 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC 300
RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC
Sbjct: 241 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC 300
Query: 301 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL 360
PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL
Sbjct: 301 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL 360
Query: 361 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR 420
TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR
Sbjct: 361 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR 420
Query: 421 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV 480
IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV
Sbjct: 421 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV 480
Query: 481 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL 540
AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL
Sbjct: 481 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL 540
Query: 541 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK 592
ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
Sbjct: 541 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK 592
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 69.7 bits (169), Expect = 7e-12
Identities = 25/58 (43%), Positives = 37/58 (63%)
Query: 317 CFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYV 374
C +C E++W CL C H+ CGRY+ HA KHF+E+ H A+++ V+ Y D+YV
Sbjct: 29 CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 69.7 bits (169), Expect = 7e-12
Identities = 25/58 (43%), Positives = 37/58 (63%)
Query: 317 CFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYV 374
C +C E++W CL C H+ CGRY+ HA KHF+E+ H A+++ V+ Y D+YV
Sbjct: 29 CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86
>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
Length = 640
Score = 69.7 bits (169), Expect = 7e-12
Identities = 28/58 (48%), Positives = 37/58 (63%)
Query: 317 CFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYV 374
C EC E++W CL C H+ CGRY+ HA KHFEET H AM++ + V+ Y +YV
Sbjct: 26 CLECATTESVWACLKCSHVACGRYIEDHALKHFEETGHPLAMEVRDLYVFCYLCKDYV 83
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 302 VCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGR-YVSRHAYKHF---EETQHTYA 357
+C+ C+T V++ E + ++W+CL CGH GCGR +HA KH+ H
Sbjct: 47 ICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLV 106
Query: 358 MQLTNHRVWDYAGDNYVHRLVASKTDGKIVQY 389
+ L N VW Y DN V + +S G++V Y
Sbjct: 107 LSLDNWSVWCYVCDNEV-QYCSSNQLGQVVDY 137
>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 302 VCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGR-YVSRHAYKHF---EETQHTYA 357
+C+ C+T V++ E + ++W+CL CGH GCGR +HA KH+ H
Sbjct: 47 ICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLV 106
Query: 358 MQLTNHRVWDYAGDNYVHRLVASKTDGKIVQY 389
+ L N VW Y DN V + +S G++V Y
Sbjct: 107 LSLDNWSVWCYVCDNEV-QYCSSNQLGQVVDY 137
>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 302 VCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGR-YVSRHAYKHF---EETQHTYA 357
+C+ C+T V++ E + ++W+CL CGH GCGR +HA KH+ H
Sbjct: 47 ICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLV 106
Query: 358 MQLTNHRVWDYAGDNYVHRLVASKTDGKIVQY 389
+ L N VW Y DN V + +S G++V Y
Sbjct: 107 LSLDNWSVWCYVCDNEV-QYCSSNQLGQVVDY 137
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 53.9 bits (128), Expect = 4e-07
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 317 CFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHR 376
C C ++ W+CL C + CGRYV+ HA KH+E+ Q + LTNH+ + D H
Sbjct: 29 CSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQ----VPLTNHKKSE-KQDKVQHT 83
Query: 377 LVASKTDGKIVQYECEGDTCQEEKIDALQ 405
+ + Y C+ + K+ +Q
Sbjct: 84 VCMDCSSYSTYCYRCDDFVVNDTKLGLVQ 112
>gi|13128864 histone deacetylase 6 [Homo sapiens]
Length = 1215
Score = 50.8 bits (120), Expect = 3e-06
Identities = 19/59 (32%), Positives = 29/59 (49%)
Query: 317 CFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVH 375
C +CG + W+CL C + CGRY++ H +H + H + + W Y YVH
Sbjct: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVH 1191
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 50.1 bits (118), Expect = 6e-06
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 317 CFECGVQ-ENLWICLI--CGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYA 369
C +C VQ NLW CL C ++GCG H+ H +ET+H + LT RVW YA
Sbjct: 61 CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHYLTVNLTTLRVWCYA 116
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 50.1 bits (118), Expect = 6e-06
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 317 CFECGVQ-ENLWICLI--CGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYA 369
C +C VQ NLW CL C ++GCG H+ H +ET+H + LT RVW YA
Sbjct: 61 CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHYLTVNLTTLRVWCYA 116
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 50.1 bits (118), Expect = 6e-06
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 317 CFECGVQ-ENLWICLI--CGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYA 369
C +C VQ NLW CL C ++GCG H+ H +ET+H + LT RVW YA
Sbjct: 30 CQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHYLTVNLTTLRVWCYA 85
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 49.7 bits (117), Expect = 8e-06
Identities = 43/161 (26%), Positives = 77/161 (47%), Gaps = 38/161 (23%)
Query: 420 RIYWENKIVRIEKDTAEEINNMKTKF---KETIEKCD----NLEHKLNDLLKEKQSV--- 469
++Y++ K + +T +E+ MK +F KET+EK + LE K+ LL+EK +
Sbjct: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQ 892
Query: 470 -----------ERKCTQL-------NTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEE 511
E +C QL KV ++ L++E+EMN L A + KL++E
Sbjct: 893 VQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK----KRKLEDE 948
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAE 552
LK+ D +L + +++++ T+ K+ +L E
Sbjct: 949 CSELKKDIDDLELTLAKVEKEKH------ATENKVKNLTEE 983
Score = 43.1 bits (100), Expect = 7e-04
Identities = 50/188 (26%), Positives = 85/188 (45%), Gaps = 32/188 (17%)
Query: 394 DTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTA--EEINNMKTKFKETIEK 451
D C E K D LE L +++E ++ ENK+ + ++ A +EI TK K+ +++
Sbjct: 947 DECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE 1003
Query: 452 C-----DNL---EHKLNDLLKEKQSVERKCTQLNTKVA--------------KLTNELKE 489
D+L E K+N L K K +E++ L + KL +LK
Sbjct: 1004 AHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
Query: 490 EQEMNKCLRANQVLLQNKLKEEE-RVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINH 548
QE L +++ L+ KLK++E + ++ +D Q+ +Q Q + E Q +I
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKK----LKENQARIEE 1119
Query: 549 LPAETRQE 556
L E E
Sbjct: 1120 LEEELEAE 1127
Score = 38.5 bits (88), Expect = 0.018
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 29/171 (16%)
Query: 415 QLESQRIYWENKIVRIEK--DTAEEINNMKTKFKETIE-KCDNLEHKLNDL-------LK 464
QL +I E K+ + + + EE+N T K +E +C L+ ++DL K
Sbjct: 909 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 968
Query: 465 EKQSVERKCTQLNTK-------VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKE 517
EK + E K L + +AKLT E K QE A+Q L + EE++V
Sbjct: 969 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE------AHQQALDDLQVEEDKV--- 1019
Query: 518 TCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMAS 568
+ ++++Q+ D+ LE ++K+ + E + EG + + S
Sbjct: 1020 --NSLSKSKVKLEQQVDDLEGSLEQEKKV-RMDLERAKRKLEGDLKLTQES 1067
Score = 38.5 bits (88), Expect = 0.018
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 23/166 (13%)
Query: 398 EEKIDALQLEYSYL--LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNL 455
E + + LQ E L + Q E R E +++ +T+E + + ++ I + +
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELI----ETSERVQLLHSQNTSLINQKKKM 1732
Query: 456 EHKLNDL-------LKEKQSVERKCTQLNTKVAKLTNELKEEQE-------MNKCLRANQ 501
E L L ++E ++ E K + T A + ELK+EQ+ M K +
Sbjct: 1733 ESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTI 1792
Query: 502 VLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKIN 547
LQ++L E E++ + + Q+ +++ ++R++ LE +QK N
Sbjct: 1793 KDLQHRLDEAEQIALKGGKK---QLQKLEARVRELEGELEAEQKRN 1835
Score = 33.9 bits (76), Expect = 0.43
Identities = 42/201 (20%), Positives = 87/201 (43%), Gaps = 19/201 (9%)
Query: 370 GDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVR 429
G VH L + ++ + E + + EE +L+ E +L +QLE +I E
Sbjct: 1521 GGKNVHELEKVRKQLEVEKLELQ--SALEEAEASLEHEEGKILRAQLEFNQIKAE----- 1573
Query: 430 IEKDTAEEINNMKTKFKETIEKCDNLEHKL-------NDLLKEKQSVERKCTQLNTKVAK 482
IE+ AE+ M+ + D+L+ L N++L+ K+ +E ++ +++
Sbjct: 1574 IERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSH 1633
Query: 483 LTNELKEEQEMNKCLRA----NQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMF 538
E Q+ K L++ Q+ L + ++ + LKE + + +Q +L ++
Sbjct: 1634 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD-LKENIAIVERRNNLLQAELEELRA 1692
Query: 539 YLETQQKINHLPAETRQEIQE 559
+E ++ L + E E
Sbjct: 1693 VVEQTERSRKLAEQELIETSE 1713
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/146 (19%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
Query: 426 KIVRIEKDTAEEINNMKTKFK-ETIEKCDNLEH-------KLNDLLKEKQSVERKCTQLN 477
++ R+ E+ +TK++ + I++ + LE +L D + ++V KC+ L
Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417
Query: 478 TKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVL---KETCDQKDLQITEIQEQLR 534
+L NE+++ + A L K + +++L K+ ++ ++ Q++ R
Sbjct: 1418 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Query: 535 DV---MFYLET--QQKINHLPAETRQ 555
+ +F L+ ++ + HL R+
Sbjct: 1478 SLSTELFKLKNAYEESLEHLETFKRE 1503
Score = 30.0 bits (66), Expect = 6.2
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 8/179 (4%)
Query: 403 ALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDL 462
++Q+E + ++ + R E ++ E A E E+ DNL+ L
Sbjct: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
Query: 463 LKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQK 522
KEK + + + + + ++ +++++ L + KL+E +R L + Q+
Sbjct: 1220 EKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR 1279
Query: 523 DLQITEIQEQLR-----DVMFYLETQQKINH---LPAETRQEIQEGQINIAMASASSPA 573
TE E R + + T+ K+++ + RQ +EG+ A+A A A
Sbjct: 1280 AKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSA 1338
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 422 YWENKIVRIEKDTAEEINNMKTKFKETIE----KCDNLEHKLNDLLKEKQSVERKCTQLN 477
Y+ ++ + + E ++++++ E + K LE L++ ++ K+ +E+KC +N
Sbjct: 415 YYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVN 474
Query: 478 TKVAKLTNELKEEQEMNKC-------LRANQVLLQNKLKEEERVLKETCDQK---DLQIT 527
T++ K EL+EE + K L + LLQ+K E +R D+K + +
Sbjct: 475 TRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVN 534
Query: 528 EIQEQLRDVMFYLETQQ----KINHL 549
+++QL D+ + Q K+N L
Sbjct: 535 SLKDQLEDLKKRNQNSQISTEKVNQL 560
Score = 36.2 bits (82), Expect = 0.087
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 34/200 (17%)
Query: 385 KIVQYECEGDTCQEEKIDALQLEYSYLLTS--QLESQRIYWENKIVRIEKDTAEEINNMK 442
K++Q E + + + A + + + S + +S+ + K + E+ +++ N+
Sbjct: 695 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 754
Query: 443 TKFKE--TIEKCD--NLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNK-CL 497
+ ++ ++ CD + K+N+LLK+K LN V LT LK EQE K CL
Sbjct: 755 LEAEKRCSLLDCDLKQSQQKINELLKQKD-------VLNEDVRNLT--LKIEQETQKRCL 805
Query: 498 RANQVLLQ-----------NKLKEEERVLKETCDQKDLQITEIQE-------QLRDVMFY 539
N + +Q +LK+E L E + Q E+++ Q++++
Sbjct: 806 TQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQ 865
Query: 540 LETQQKINHLPAETRQEIQE 559
LE +Q + L +E++E
Sbjct: 866 LEAEQYFSTLYKTQVRELKE 885
Score = 31.2 bits (69), Expect = 2.8
Identities = 28/129 (21%), Positives = 60/129 (46%), Gaps = 15/129 (11%)
Query: 442 KTKFKETIEKCD-------NLEHKLNDLLKEKQSVERKCTQLNTKV--AKLTNELKEEQE 492
KT+ +E E+C+ L+ K +L E+ S+ + TK +L + EEQ
Sbjct: 877 KTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQY 936
Query: 493 MNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLR----DVMFYLETQQKINH 548
+ L +++ + ++KE K+ +KD I ++E R DV ++++N+
Sbjct: 937 SD--LEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNN 994
Query: 549 LPAETRQEI 557
+ ++++
Sbjct: 995 KLKDVQEQL 1003
>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
Length = 752
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/189 (23%), Positives = 89/189 (47%), Gaps = 22/189 (11%)
Query: 398 EEKIDALQLEYSYLLTSQLES--QRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNL 455
EE++ L+ + LL +LE Q++ W + E++ K + + ++L
Sbjct: 399 EEQVQQLEAQVQ-LLVGRLEGAGQQVCW----------ASTELDKEKARVDSMVRHQESL 447
Query: 456 EHKLNDLLKEKQSVERKCTQLNTKV-------AKLTNELKEEQEMNKC-LRANQVLLQNK 507
+ K LLK+ S++++ +L + A++ +L+ E+E +C LRA Q LLQ+
Sbjct: 448 QAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQLQSEREQGQCQLRAQQELLQSL 507
Query: 508 LKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMA 567
+E++ + + T D + L I E++ +L ++ L T +I G+ + +
Sbjct: 508 QREKQGLEQATTDLR-LTILELERELEELKERERLLVAFPDLHRPTETQIHGGRSSSVES 566
Query: 568 SASSPASSG 576
+ P SG
Sbjct: 567 QITCPTDSG 575
Score = 35.0 bits (79), Expect = 0.19
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 456 EHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVL 515
E L++ +KQ + + + L TK+A L ELK+++E + + A LQ + E
Sbjct: 333 EQCLSEWEHDKQQLLTETSDLKTKMATLERELKQQRESTQAVEAKAQQLQEE-GERRAAA 391
Query: 516 KETCDQKDLQITEIQEQLRDVMFYLE 541
+ Q + Q+ +++ Q++ ++ LE
Sbjct: 392 ERQVQQLEEQVQQLEAQVQLLVGRLE 417
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/140 (25%), Positives = 74/140 (52%), Gaps = 5/140 (3%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Q + LLT Q+ S I ++K V+IE E+++++ +F E +L+ +L +
Sbjct: 787 QTAHDNLLTEQIHSLSIEAKSKDVKIEV-LQNELDDVQLQFSEQSTLIRSLQSQLQNKES 845
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
E + +++KV +L+ L +++ + + +Q+LL+ K E L++T ++KD
Sbjct: 846 EVLEGAERVRHISSKVEELSQALSQKEL--EITKMDQLLLEKKRDVE--TLQQTIEEKDQ 901
Query: 525 QITEIQEQLRDVMFYLETQQ 544
Q+TEI + + M L ++
Sbjct: 902 QVTEISFSMTEKMVQLNEEK 921
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/167 (22%), Positives = 81/167 (48%), Gaps = 11/167 (6%)
Query: 397 QEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINN----MKTKFKETIEKC 452
+ K+DA ++Y L +Q+ + + + +++ ++ +E+ N ++ K KE+ E
Sbjct: 2525 ENAKLDAELIQYREDL-NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAN 2583
Query: 453 DNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEE 512
++L N L +EKQ + ++ L +++LT ++ QE Q K+KEEE
Sbjct: 2584 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEG---TLGLYHAQLKVKEEE 2640
Query: 513 -RVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQ 558
L +I E++E+L V E +K+ + + ++E++
Sbjct: 2641 VHRLSALFSSSQKRIAELEEEL--VCVQKEAAKKVGEIEDKLKKELK 2685
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 16/163 (9%)
Query: 390 ECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETI 449
+C D + K L+LE ++ ++Q IY +N + A+EI+N+ +E
Sbjct: 680 QCHQDELERLKSQILELELNFH-----KAQEIYEKNL-----DEKAKEISNLNQLIEEFK 729
Query: 450 EKCDNLEHKLNDLLKEKQSVERK------CTQLNTKVAKLTNELKEEQEMNKCLRANQVL 503
+ DN L +E+ + + T+L +V +L L E + + +Q
Sbjct: 730 KNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTA 789
Query: 504 LQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKI 546
N L E+ L KD++I +Q +L DV Q +
Sbjct: 790 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTL 832
Score = 37.7 bits (86), Expect = 0.030
Identities = 36/175 (20%), Positives = 80/175 (45%), Gaps = 38/175 (21%)
Query: 431 EKDTAEEINNMKTKFKETIEKC--------DNLEHKLNDLLKEKQSVERKC--------- 473
+K+ EE N + + K+ ++ + L+H+ + L KE + +RK
Sbjct: 945 KKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKE 1004
Query: 474 -----TQLNTKVAKLTNELKEEQEMNKCLRA-----------NQVLLQNKLKEEERVLKE 517
++L ++A L +E K+E +++ R ++ + +K +E E LK+
Sbjct: 1005 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1064
Query: 518 TCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQE--GQINIAMASAS 570
T +K++++ I++ L + L +++ L + Q +Q+ QI++ A S
Sbjct: 1065 TISEKEVELQHIRKDLEE---KLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEIS 1116
Score = 37.0 bits (84), Expect = 0.051
Identities = 36/146 (24%), Positives = 69/146 (47%), Gaps = 21/146 (14%)
Query: 412 LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVER 471
L SQ E + I E + + T + + +KT KE I++ + +L+ +K S++
Sbjct: 2416 LLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ----KAQLDSFVKSMSSLQN 2471
Query: 472 KCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQ-----NKLKEEERVLKETCD------ 520
++ +L EE+ ++ L +Q++ + NKLKEE R L+ D
Sbjct: 2472 DRDRIVGDYQQL-----EERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2526
Query: 521 -QKDLQITEIQEQLRDVMFYLETQQK 545
+ D ++ + +E L V+ ++QQK
Sbjct: 2527 AKLDAELIQYREDLNQVITIKDSQQK 2552
Score = 35.4 bits (80), Expect = 0.15
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 18/137 (13%)
Query: 426 KIVRIEKDTAEEINNMKTKFKETIEK-CDNLEHKL-NDLLKEKQSVERKCTQLNTKVAKL 483
K+ + + EE++ + TK KET E+ D+LE +L N L + S+ C + A++
Sbjct: 1893 KMNLLNQQIQEELSRV-TKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTD--AQI 1949
Query: 484 TNELKEEQ--EMNKCL----RANQVLLQNKLKEEERVLKETCD-----QKDLQITEIQEQ 532
NEL E + + KC+ Q L++ K K E + KE + QK+ ++
Sbjct: 1950 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE 2009
Query: 533 LRDVMFYLETQQKINHL 549
L++++ E QQ++ L
Sbjct: 2010 LQELL--KEKQQEVKQL 2024
Score = 33.9 bits (76), Expect = 0.43
Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 18/146 (12%)
Query: 432 KDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNE----L 487
K EE++ + + + ++E +++ KEK +V + L + KL E L
Sbjct: 1500 KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSL 1559
Query: 488 KEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQI---TEIQEQLRDVMFYLE--- 541
E Q ++ + ++ L+ +++E+++KE K +I TE QE+ +++ E
Sbjct: 1560 LENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1619
Query: 542 --------TQQKINHLPAETRQEIQE 559
++I H+ RQE QE
Sbjct: 1620 QSYENVSNEAERIQHVVEAVRQEKQE 1645
Score = 32.7 bits (73), Expect = 0.96
Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Query: 460 NDLLKEKQSVERKCTQLNTKVAKLTNELKEEQ----EMNKCLRANQVLLQNK----LKEE 511
N L ++ S+ + + K+ L NEL + Q E + +R+ Q LQNK L+
Sbjct: 792 NLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGA 851
Query: 512 ERV---------LKETCDQKDLQITEIQEQLRDVMFYLETQQK 545
ERV L + QK+L+IT++ + L + +ET Q+
Sbjct: 852 ERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQ 894
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/146 (19%), Positives = 73/146 (50%), Gaps = 10/146 (6%)
Query: 414 SQLESQRIYWENKIVRIEKD------TAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQ 467
+ L+++R + N++ + K +A + + + + + +L++ + LLKE +
Sbjct: 2839 ASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELK 2898
Query: 468 SVERKCTQLN---TKVAKLTNELKEEQEMNKCLRANQ-VLLQNKLKEEERVLKETCDQKD 523
+++++ Q+N T++ L +L+E Q+ K + Q L Q L + + + ++
Sbjct: 2899 NLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSS 2958
Query: 524 LQITEIQEQLRDVMFYLETQQKINHL 549
+I E + + + +M + Q+++HL
Sbjct: 2959 WEIHERRMKEQYLMAISDKDQQLSHL 2984
Score = 31.6 bits (70), Expect = 2.1
Identities = 35/172 (20%), Positives = 67/172 (38%), Gaps = 32/172 (18%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
QL + L +L S + V+ ++ + E + + + + + L +LND LK
Sbjct: 2980 QLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLK 3039
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
E E + QLN+ ++L L+E+ + + CD
Sbjct: 3040 EIHQKELRIQQLNSNFSQL------------------------LEEKNTLSIQLCDTSQ- 3074
Query: 525 QITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSG 576
+ E Q+ D++ + +K QE+Q G +NI +A + +G
Sbjct: 3075 SLRENQQHYGDLLNHCAVLEK-------QVQELQAGPLNIDVAPGAPQEKNG 3119
Score = 31.2 bits (69), Expect = 2.8
Identities = 29/155 (18%), Positives = 70/155 (45%), Gaps = 8/155 (5%)
Query: 414 SQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKC 473
SQ++ + E ++ + E+ +E NM+ K + +LE + ++ +++
Sbjct: 2114 SQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEV 2173
Query: 474 TQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQI------- 526
QL + +L + L+ ++ + ++ K+ ER + K+ +I
Sbjct: 2174 QQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNC 2233
Query: 527 TEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQ 561
+ +++QLR + ++E + KIN E ++I E +
Sbjct: 2234 SVLKDQLRQMSIHME-ELKINISRLEHDKQIWESK 2267
Score = 30.8 bits (68), Expect = 3.7
Identities = 40/144 (27%), Positives = 65/144 (45%), Gaps = 16/144 (11%)
Query: 412 LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVER 471
L+S ES ++ E EK +EI ++K+ I + + K +L KE +
Sbjct: 1565 LSSSCESLKLALEGLTEDKEK-LVKEIESLKSS---KIAESTEWQEKHKELQKEYEI--- 1617
Query: 472 KCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQ- 530
L ++NE + Q + + +R + L KL+ E KET +K LQ E +
Sbjct: 1618 ----LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKET--EKQLQEAEQEM 1671
Query: 531 EQLRDVM--FYLETQQKINHLPAE 552
E++++ M F QQKI L E
Sbjct: 1672 EEMKEKMRKFAKSKQQKILELEEE 1695
Score = 30.8 bits (68), Expect = 3.7
Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 8/133 (6%)
Query: 397 QEEKIDALQLEYSYLLTSQLESQRIYWEN---KIVRIEKDTAEEINNMKTKFKETIEKCD 453
+EE+I L+ + +L QL I+ E I R+E D + +T+ + + CD
Sbjct: 2222 KEEEI-RLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2280
Query: 454 NLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEER 513
L+ + +LL + + ++AKL +ELK ++ L +N + K KE++
Sbjct: 2281 TLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL-SNSL---EKCKEQKG 2336
Query: 514 VLKETCDQKDLQI 526
L+ Q++ I
Sbjct: 2337 NLEGIIRQQEADI 2349
Score = 30.0 bits (66), Expect = 6.2
Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 8/116 (6%)
Query: 425 NKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLT 484
N V + + +EINN + + E+ LE + + Q++E + L ++++
Sbjct: 1822 NPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKD 1881
Query: 485 NELKEEQEMNKCLRANQVLLQNKLKEE-ERV--LKETCDQKDLQITE-IQEQLRDV 536
ELK QE + + N LL +++EE RV LKET +++ + E + QL ++
Sbjct: 1882 GELKMLQE--EVTKMN--LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAEL 1933
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/185 (25%), Positives = 94/185 (50%), Gaps = 26/185 (14%)
Query: 394 DTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKD-TAEEINNMK-TKFKETIEK 451
D C K D LE L +++E ++ ENK+ + ++ TA E N K TK K+++++
Sbjct: 949 DKCSSLKRDIDDLE---LTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQE 1005
Query: 452 CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNK---- 507
+ L+DL E+ V ++N K+ + T++L+ E K LRA+ + K
Sbjct: 1006 AH--QQTLDDLQVEEDKVNG-LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062
Query: 508 ----------LKEEERVLKETCDQKDLQITEIQEQLRDVMFY-LETQQKINHLPA---ET 553
L+ +++ ++E +K+ +++++Q ++ D + L+ Q+KI L A E
Sbjct: 1063 LKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 554 RQEIQ 558
+EI+
Sbjct: 1123 EEEIE 1127
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 27/146 (18%)
Query: 424 ENKIVRIEKD---TAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQS-------VERKC 473
E ++ +++D T EE+ + + KE EK +L + NDL + QS E +C
Sbjct: 850 EKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERC 909
Query: 474 TQL-------NTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQI 526
L KV +LT L+EE+EMN L A + L++K LK D +L +
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSS----LKRDIDDLELTL 965
Query: 527 TEIQEQLRDVMFYLETQQKINHLPAE 552
T+++++ T+ K+ +L E
Sbjct: 966 TKVEKEKH------ATENKVKNLSEE 985
Score = 40.4 bits (93), Expect = 0.005
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 13/140 (9%)
Query: 413 TSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERK 472
T +L Q + + V++ + N K K + I +C + ++ + ++E ++ E K
Sbjct: 1702 TRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQC---QAEVENSIQESRNAEEK 1758
Query: 473 CTQLNTKVAKLTNELKEEQE-------MNKCLRANQVLLQNKLKEEERVLKETCDQKDLQ 525
+ T A + ELK+EQ+ M K L LQ++L E E++ + + Q
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK---Q 1815
Query: 526 ITEIQEQLRDVMFYLETQQK 545
I +++ ++R++ L+ +QK
Sbjct: 1816 IQKLENRVRELENELDVEQK 1835
Score = 39.3 bits (90), Expect = 0.010
Identities = 50/213 (23%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 379 ASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEI 438
A KT + Q + + EE +L+ E S +L QLE ++ E IEKD EEI
Sbjct: 1530 AEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKD--EEI 1587
Query: 439 NNMKTKFKETIEKCDNL----EHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMN 494
+K + E ++ ND L+ K+ +E ++ ++ ++ E Q
Sbjct: 1588 EQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQ--- 1644
Query: 495 KCLRANQVLLQNKLKEEERVLKETCDQKD-LQITE-----IQEQLRDVMFYLETQQKINH 548
K LR Q L++ + L+ D K+ L I E + E+L ++ LE ++
Sbjct: 1645 KHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRR 1704
Query: 549 LPAETRQEIQEGQINIAMASASSPASSGGSGKL 581
L + QE+ + + + + + + KL
Sbjct: 1705 L---SEQELLDASDRVQLLHSQNTSLINTKKKL 1734
Score = 35.8 bits (81), Expect = 0.11
Identities = 50/203 (24%), Positives = 93/203 (45%), Gaps = 28/203 (13%)
Query: 377 LVASKTDGKI-VQYECEGDTCQEEKIDALQLEYSYLLTSQLE--SQRIYWENKIVRIEKD 433
L+ K D ++ VQ E E EE+ + L ++ LL ++++ ++R+ E ++ +
Sbjct: 884 LLQEKNDLQLQVQSETENLMDAEERCEGL-IKSKILLEAKVKELTERLEEEEEM---NSE 939
Query: 434 TAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERK-------CTQLNTKVAKLTNE 486
+ N++ K D+LE L + KEK + E K T L ++KLT E
Sbjct: 940 LVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKE 999
Query: 487 LKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQI-TEIQEQLRDVMFYLETQQK 545
K QE A+Q L + EE++V ++I ++++Q D+ LE ++K
Sbjct: 1000 KKSLQE------AHQQTLDDLQVEEDKV------NGLIKINAKLEQQTDDLEGSLEQEKK 1047
Query: 546 INHLPAETRQEIQEGQINIAMAS 568
+ E + EG + ++ S
Sbjct: 1048 L-RADLERAKRKLEGDLKMSQES 1069
Score = 35.0 bits (79), Expect = 0.19
Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 410 YLLTSQLESQRIYWENKIVRIEK-----DTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Y + S + + W N +I+ + +E+ MK F+ T E+ E + +L +
Sbjct: 820 YNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEE 879
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKE 517
+ S+ ++ L +V T L + +E + L +++LL+ K+KE L+E
Sbjct: 880 KMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEE 932
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 17/168 (10%)
Query: 398 EEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEK--DTAEEINNMKTKFKETIEKCDNL 455
++KI L+LE T ++SQ E + K D E+I +++ K + + C
Sbjct: 315 QQKIKELELEV-LKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVC--- 370
Query: 456 EHKLNDL-LKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNK---LKEE 511
L D + EKQ +E K + AK+ + +EEQ+ K L N L + L+++
Sbjct: 371 ---LTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDK 427
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQE 559
E +L+ TC Q+ +I + + L+ LE +++ ++ QE+ E
Sbjct: 428 ENLLEMTCSQQQSRIQQQEALLKQ----LENEKRKYDEHVKSNQELSE 471
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 317 CFECGVQ-ENLWICL--ICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNY 373
C CGV NLW CL C ++GCG + H+ H + +H + LT R+W YA +
Sbjct: 30 CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHNLTVNLTTFRLWCYACEKE 89
Query: 374 V 374
V
Sbjct: 90 V 90
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 317 CFECGVQ-ENLWICL--ICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNY 373
C CGV NLW CL C ++GCG + H+ H + +H + LT R+W YA +
Sbjct: 30 CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHNLTVNLTTFRLWCYACEKE 89
Query: 374 V 374
V
Sbjct: 90 V 90
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 317 CFECGVQ-ENLWICL--ICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNY 373
C CGV NLW CL C ++GCG + H+ H + +H + LT R+W YA +
Sbjct: 30 CQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHNLTVNLTTFRLWCYACEKE 89
Query: 374 V 374
V
Sbjct: 90 V 90
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/220 (22%), Positives = 98/220 (44%), Gaps = 21/220 (9%)
Query: 390 ECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIE--KDTAEEINNMKTKFKE 447
E + +T QEE + AL+ + + SQL Q N + + KD + +N+M+ ++++
Sbjct: 275 EMQYETLQEELM-ALKKNHKEEM-SQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQ 332
Query: 448 TIEK------------CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNK 495
I K +EH+++ +E QS ++ TQL V +L EL+ +
Sbjct: 333 LIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKA 392
Query: 496 CLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQL----RDVMFYLETQQKINHLPA 551
L + +N+ + ++++E + QIT++++++ ++ L + ++
Sbjct: 393 ALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEK-EI 451
Query: 552 ETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRG 591
ET + EG +S + GG G GR RG
Sbjct: 452 ETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRG 491
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/128 (29%), Positives = 69/128 (53%), Gaps = 6/128 (4%)
Query: 449 IEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKL 508
I++ D L +++ DL +EK +VE+ + + + T+E+++ Q+ + R N L KL
Sbjct: 332 IKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQD--EVQRENTNL--QKL 387
Query: 509 KEEERVLKETCDQKDLQITEIQEQLRDV-MFYLETQQKINHLPAE-TRQEIQEGQINIAM 566
+ +++ ++E D+ D Q +++EQL++V E Q I+ L AE T QE Q +
Sbjct: 388 QAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL 447
Query: 567 ASASSPAS 574
A A S
Sbjct: 448 AKAREELS 455
Score = 36.6 bits (83), Expect = 0.067
Identities = 30/138 (21%), Positives = 64/138 (46%), Gaps = 17/138 (12%)
Query: 430 IEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK---EKQSVERKCTQLNTKVAKLTNE 486
+E+D E+ + +K + E + D ++ + +L K +KQ V+ +L+ + A+L +
Sbjct: 352 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 411
Query: 487 LKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKI 546
LKE ++ KC Q++ LK ++ QI+ +E+L E ++
Sbjct: 412 LKEVRK--KCAEEAQLISS---------LKAELTSQESQISTYEEELAKAR---EELSRL 457
Query: 547 NHLPAETRQEIQEGQINI 564
AE + ++ G+ +
Sbjct: 458 QQETAELEESVESGKAQL 475
Score = 34.3 bits (77), Expect = 0.33
Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Query: 433 DTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQE 492
D E NN++ KE K D ++ + +++ + V+R+ NT + KL + ++ QE
Sbjct: 344 DLQREKNNVEQDLKE---KEDTIKQRTSEVQDLQDEVQRE----NTNLQKLQAQKQQVQE 396
Query: 493 MNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAE 552
+ L + L+ +LKE + E E+ Q + Y E K +
Sbjct: 397 LLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 456
Query: 553 TRQEIQEGQINIAMASA 569
+QE E + ++ A
Sbjct: 457 LQQETAELEESVESGKA 473
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 38/161 (23%)
Query: 420 RIYWENKIVRIEKDTAEEINNMKTKFKETIE-------KCDNLEHKLNDLLKEKQSV--- 469
++Y++ K + +T +E+ NMK +F++T E K LE K+ L++EK +
Sbjct: 835 KLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894
Query: 470 -----------ERKC-------TQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEE 511
E +C QL K+ ++T ++E+E+N L A + KL++E
Sbjct: 895 VQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAE 552
LK+ D +L + +++++ T+ K+ +L E
Sbjct: 951 CSELKKDIDDLELTLAKVEKEKH------ATENKVKNLTEE 985
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/215 (28%), Positives = 96/215 (44%), Gaps = 39/215 (18%)
Query: 380 SKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTS---------QLESQRIYWENKIVRI 430
+KT+ K + E + T +EK D LQL+ S QL +I E KI +
Sbjct: 868 AKTEAKRKELEEKMVTLMQEKND-LQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEV 926
Query: 431 EK--DTAEEINNMKTKFKETIE-KCDNLEHKLNDLL-------KEKQSVERKCTQLNTK- 479
+ + EEIN T K +E +C L+ ++DL KEK + E K L +
Sbjct: 927 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 986
Query: 480 ------VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQL 533
+AKLT E K QE A+Q L + EE++V T + ++++Q+
Sbjct: 987 AGLDETIAKLTKEKKALQE------AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQV 1035
Query: 534 RDVMFYLETQQKINHLPAETRQEIQEGQINIAMAS 568
D+ LE ++KI + E + EG + +A S
Sbjct: 1036 DDLEGSLEQEKKI-RMDLERAKRKLEGDLKLAQES 1069
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/165 (24%), Positives = 79/165 (47%), Gaps = 21/165 (12%)
Query: 398 EEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEE----INNMKTKFKETIEKCD 453
E + + LQ E L + +++R KI E A E ++ T T +K +
Sbjct: 1679 ERRANLLQAEIEELRATLEQTER---SRKIAEQELLDASERVQLLHTQNTSLINTKKKLE 1735
Query: 454 N----LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQE-------MNKCLRANQV 502
++ ++ D+++E ++ E K + T A + ELK+EQ+ M K L
Sbjct: 1736 TDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1795
Query: 503 LLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKIN 547
LQ++L E E++ + + QI +++ ++R++ +E++QK N
Sbjct: 1796 DLQHRLDEAEQLALKGGKK---QIQKLEARVRELEGEVESEQKRN 1837
Score = 39.3 bits (90), Expect = 0.010
Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 42/202 (20%)
Query: 394 DTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTA----------EEINNMKT 443
D C E K D LE L +++E ++ ENK+ + ++ A +E ++
Sbjct: 949 DECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1005
Query: 444 KFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA--------------KLTNELKE 489
++T++ E K+N L K K +E++ L + KL +LK
Sbjct: 1006 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKL 1065
Query: 490 EQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVM-FYLETQQKINH 548
QE + ++ L KLK +K+ +++ +Q ++ D ++ Q+KI
Sbjct: 1066 AQESTMDIENDKQQLDEKLK-----------KKEFEMSGLQSKIEDEQALGMQLQKKIKE 1114
Query: 549 LPA---ETRQEIQEGQINIAMA 567
L A E +EI+ + + A A
Sbjct: 1115 LQARIEELEEEIEAERASRAKA 1136
Score = 38.5 bits (88), Expect = 0.018
Identities = 31/138 (22%), Positives = 66/138 (47%), Gaps = 20/138 (14%)
Query: 433 DTAEEINNMKTKFKETIEK--------CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLT 484
+ E+I+N++ + K+ +EK D+L + + K K ++E+ C L +++++
Sbjct: 1206 ELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
Query: 485 NELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQ-------EQLRDVM 537
+ +E+Q + L A + LQ + E R L D+KD ++++ +Q+ ++
Sbjct: 1265 TKEEEQQRLINDLTAQRARLQTESGEYSRQL----DEKDTLVSQLSRGKQAFTQQIEELK 1320
Query: 538 FYLETQQKINHLPAETRQ 555
LE + K A Q
Sbjct: 1321 RQLEEEIKAKSALAHALQ 1338
Score = 33.5 bits (75), Expect = 0.56
Identities = 34/165 (20%), Positives = 67/165 (40%), Gaps = 21/165 (12%)
Query: 375 HRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDT 434
H L +S+ D +++ + E + QE K + + S+ S+ W K
Sbjct: 1335 HALQSSRHDCDLLREQYEEE--QEAKAELQRA------MSKANSEVAQWRTKYETDAIQR 1386
Query: 435 AEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMN 494
EE+ K K L +L D + ++V KC L +L NE+++
Sbjct: 1387 TEELEEAKKK----------LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDV 1436
Query: 495 KCLRANQVLLQNKLKEEERVL---KETCDQKDLQITEIQEQLRDV 536
+ A L K + +++L K+ C++ ++ Q++ R +
Sbjct: 1437 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSL 1481
Score = 32.0 bits (71), Expect = 1.6
Identities = 39/180 (21%), Positives = 72/180 (40%), Gaps = 22/180 (12%)
Query: 378 VASKTDGKIVQYECEGDTCQEEKIDALQLEYSYL------------LTSQLESQRIYWEN 425
V S+ D KI + + E D + I ++ S L L ++E E
Sbjct: 1572 VKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1631
Query: 426 KIVRIEKDTAEEINNMKTK---FKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAK 482
++ + AE + N + K+T D+ DL ++ VER+ L ++ +
Sbjct: 1632 QLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1691
Query: 483 LTNELKEEQEMNKCLRANQVLLQ-----NKLKEEERVLKETCDQKDLQITEIQEQLRDVM 537
L L++ + K A Q LL L + L T + + I++IQ ++ D++
Sbjct: 1692 LRATLEQTERSRKI--AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
Score = 30.8 bits (68), Expect = 3.7
Identities = 26/132 (19%), Positives = 55/132 (41%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Q+E + ++ + R E ++ E A E E+ DNL+ L K
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1223
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
EK ++ + L + + ++ ++M + L ++ K +E++R++ + Q+
Sbjct: 1224 EKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRAR 1283
Query: 525 QITEIQEQLRDV 536
TE E R +
Sbjct: 1284 LQTESGEYSRQL 1295
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 38/161 (23%)
Query: 420 RIYWENKIVRIEKDTAEEINNMKTKFKETIE-------KCDNLEHKLNDLLKEKQSV--- 469
++Y++ K + +T +E+ NMK +F++T E K LE K+ L++EK +
Sbjct: 835 KLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894
Query: 470 -----------ERKC-------TQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEE 511
E +C QL K+ ++T ++E+E+N L A + KL++E
Sbjct: 895 VQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAE 552
LK+ D +L + +++++ T+ K+ +L E
Sbjct: 951 CSELKKDIDDLELTLAKVEKEKH------ATENKVKNLTEE 985
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/214 (28%), Positives = 97/214 (45%), Gaps = 37/214 (17%)
Query: 380 SKTDGKIVQYECEGDTCQEEKIDA---LQLEYSYLLTS-----QLESQRIYWENKIVRIE 431
+KT+ K + E + T +EK D +Q E L + QL +I E KI +
Sbjct: 868 AKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVT 927
Query: 432 K--DTAEEINNMKTKFKETIE-KCDNLEHKLNDLL-------KEKQSVERKCTQLNTK-- 479
+ + EEIN T K +E +C L+ ++DL KEK + E K L +
Sbjct: 928 ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 987
Query: 480 -----VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLR 534
+AKLT E K QE A+Q L + EE++V T + T++++Q+
Sbjct: 988 GLDETIAKLTKEKKALQE------AHQQTLDDLQMEEDKVNTLTKAK-----TKLEQQVD 1036
Query: 535 DVMFYLETQQKINHLPAETRQEIQEGQINIAMAS 568
D+ LE ++K+ + E + EG + +A S
Sbjct: 1037 DLEGSLEQEKKL-CMDLERAKRKLEGDLKLAQES 1069
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/202 (23%), Positives = 85/202 (42%), Gaps = 42/202 (20%)
Query: 394 DTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTA----------EEINNMKT 443
D C E K D LE L +++E ++ ENK+ + ++ A +E ++
Sbjct: 949 DECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1005
Query: 444 KFKETIEKCDNLEHKLNDLLKEKQSVERK--------------CTQLNTKVAKLTNELKE 489
++T++ E K+N L K K +E++ C L KL +LK
Sbjct: 1006 AHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKL 1065
Query: 490 EQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVM-FYLETQQKINH 548
QE ++ L KLK +K+ +++ +Q ++ D ++ Q+KI
Sbjct: 1066 AQESTMDTENDKQQLNEKLK-----------KKEFEMSNLQGKIEDEQALAIQLQKKIKE 1114
Query: 549 LPA---ETRQEIQEGQINIAMA 567
L A E +EI+ + + A A
Sbjct: 1115 LQARIEELEEEIEAERASRAKA 1136
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/113 (24%), Positives = 61/113 (53%), Gaps = 9/113 (7%)
Query: 440 NMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRA 499
N K K + I + ++ ++ D+++E ++ E K + T A + ELK+EQ+ + L
Sbjct: 1729 NTKKKLETDISQ---IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
Query: 500 NQVLLQNKLKEEERVLKETCDQKDL-----QITEIQEQLRDVMFYLETQQKIN 547
+ ++ +K+ + L E +Q L QI +++ ++R++ +E++QK N
Sbjct: 1786 MKKNMEQTVKDLQLRLDE-AEQLALKGGKKQIQKLEARVRELESEVESEQKHN 1837
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/132 (20%), Positives = 55/132 (41%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Q+E + ++ + R E ++ E A E E+ D+L+ L K
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEK 1223
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
EK ++ + L + + ++ ++M + L ++ K +E++R++ E QK
Sbjct: 1224 EKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKAR 1283
Query: 525 QITEIQEQLRDV 536
TE E R +
Sbjct: 1284 LHTESGEFSRQL 1295
Score = 31.2 bits (69), Expect = 2.8
Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 28/148 (18%)
Query: 437 EINNMKTKFK-ETIEKCDNLEH-------KLNDLLKEKQSVERKCTQLNTKVAKLTNELK 488
E+ +TK++ + I++ + LE +L D + ++V KC L +L NE++
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
Query: 489 E-----EQEMNKCL-------RANQVLLQNKLKEEERVLKETCDQKD-----LQITEIQE 531
+ E+ C+ ++VL + K K EE + QK+ ++ +++
Sbjct: 1431 DLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKN 1490
Query: 532 QLRDVMFYLETQQKINHLPAETRQEIQE 559
+ + +LET ++ N +QEI +
Sbjct: 1491 AYEESLDHLETLKREN---KNLQQEISD 1515
Score = 30.8 bits (68), Expect = 3.7
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 22/180 (12%)
Query: 378 VASKTDGKIVQYECEGDTCQEEKIDALQLEYSYL------------LTSQLESQRIYWEN 425
V S+ D KI + + E D + + ++ S L + ++E E
Sbjct: 1572 VKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEI 1631
Query: 426 KIVRIEKDTAEEINNMKTK---FKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAK 482
++ + AE + N++ K+T D+ +DL ++ VER+ + +V +
Sbjct: 1632 QLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEE 1691
Query: 483 LTNELKEEQEMNKCLRANQVLLQ-----NKLKEEERVLKETCDQKDLQITEIQEQLRDVM 537
L L+ + K A Q LL L + L T + + I++IQ ++ D++
Sbjct: 1692 LRASLERTERGRK--MAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIV 1749
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/210 (28%), Positives = 93/210 (44%), Gaps = 42/210 (20%)
Query: 377 LVASKTDGKI-VQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEK--D 433
L+ K D ++ VQ E EG EE+ D QL +I E KI + + +
Sbjct: 886 LLKEKNDLQLQVQAEAEGLADAEERCD------------QLIKTKIQLEAKIKEVTERAE 933
Query: 434 TAEEINNMKTKFKETIE-KCDNLEHKLNDLL-------KEKQSVERKCTQLNTK------ 479
EEIN T K +E +C L+ ++DL KEK + E K L +
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 993
Query: 480 -VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMF 538
+AKLT E K QE A+Q L + EE++V T + ++++Q+ D+
Sbjct: 994 TIAKLTKEKKALQE------AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEG 1042
Query: 539 YLETQQKINHLPAETRQEIQEGQINIAMAS 568
LE ++K+ + E + EG + +A S
Sbjct: 1043 SLEQEKKL-RMDLERAKRKLEGDLKLAQES 1071
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/163 (23%), Positives = 79/163 (48%), Gaps = 17/163 (10%)
Query: 398 EEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEE----INNMKTKFKETIEKCD 453
E + + LQ E L + +++R KI E A E ++ T T +K +
Sbjct: 1681 ERRANLLQAEIEELRATLEQTER---SRKIAEQELLDASERVQLLHTQNTSLINTKKKLE 1737
Query: 454 N----LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLK 509
++ ++ D+L+E ++ E K + T A + ELK+EQ+ + L + ++ +K
Sbjct: 1738 TDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK 1797
Query: 510 EEERVLKETCDQKDL-----QITEIQEQLRDVMFYLETQQKIN 547
+ + L E +Q L QI +++ ++R++ +E++QK N
Sbjct: 1798 DLQLRLDE-AEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839
Score = 39.3 bits (90), Expect = 0.010
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 370 GDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVR 429
G +H L K ++ Q +CE EE +L+ E +L QLE ++ E
Sbjct: 1525 GGKRIHEL--EKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582
Query: 430 IEKDTAEEINNMKTKFKETIEKCDN-LEHKL---NDLLKEKQSVERKCT----QLNTKVA 481
EKD EEI+ +K +E + L+ ++ ND ++ K+ +E QLN
Sbjct: 1583 AEKD--EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLE 541
L+ + L+ Q+ L + L+ +E LKE + + +Q ++ ++ LE
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQED-LKEQLAMVERRANLLQAEIEELRATLE 1699
Query: 542 TQQK 545
++
Sbjct: 1700 QTER 1703
Score = 38.9 bits (89), Expect = 0.013
Identities = 37/173 (21%), Positives = 74/173 (42%), Gaps = 18/173 (10%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEI---NNMKTKFKETIEKCDNLEHKLND 461
QL+ L SQL + + +I +++ EEI N + + + CD L + +
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 462 LLKEKQSVERKCTQLNTKVAKLTNELKEE--QEMNKCLRANQVLLQNKLKEEERV--LKE 517
+ K ++R ++ NT+VA+ + + + Q + A + L Q EE V +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 518 TCDQKDLQITEIQEQLRDVMFYLE-----------TQQKINHLPAETRQEIQE 559
C + +Q ++ D+M +E Q+ + + AE +Q+ +E
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Score = 37.0 bits (84), Expect = 0.051
Identities = 29/139 (20%), Positives = 67/139 (48%), Gaps = 16/139 (11%)
Query: 433 DTAEEINNMKTKFKETIEK--------CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLT 484
+ E+I+N++ + K+ +EK D+L + + K K ++E+ C L ++++L
Sbjct: 1208 ELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266
Query: 485 NELKEEQEMNKCLRANQVLLQNK-------LKEEERVLKETCDQKDLQITEIQEQLRDVM 537
++ +E+Q + L A + LQ + L E+E ++ + K +I+E R +
Sbjct: 1267 SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLE 1326
Query: 538 FYLETQQKINHLPAETRQE 556
++ + + H +R +
Sbjct: 1327 EEIKAKNALAHALQSSRHD 1345
Score = 32.3 bits (72), Expect = 1.3
Identities = 32/168 (19%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Query: 381 KTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINN 440
+T K+ + + ++ +D LQ E + T L +I E ++ +E +E
Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT--LTKAKIKLEQQVDDLEGSLEQE-KK 1049
Query: 441 MKTKFKETIEKCDN----LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKC 496
++ + K + + + D+ EKQ ++ K + +++ L +++++EQ +
Sbjct: 1050 LRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQ 1109
Query: 497 LRANQVLLQNKLKE-EERVLKETCD--QKDLQITEIQEQLRDVMFYLE 541
L+ LQ +++E EE + E + + Q +++ +L ++ LE
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/132 (21%), Positives = 56/132 (42%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Q+E + ++ + R E ++ E A E E+ DNL+ L K
Sbjct: 1166 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1225
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
EK ++ + L + V ++ ++M + L L++K +E++R++ + Q+
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285
Query: 525 QITEIQEQLRDV 536
TE E R +
Sbjct: 1286 LQTESGEFSRQL 1297
Score = 31.6 bits (70), Expect = 2.1
Identities = 38/188 (20%), Positives = 76/188 (40%), Gaps = 38/188 (20%)
Query: 378 VASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLES--QRIYWENKIVRIEKDTA 435
V S+ D KI + ++E+ID L+ + ++ S + I N +R++K
Sbjct: 1574 VKSEVDRKIAE--------KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1625
Query: 436 EEINNMKTKF---------------------KETIEKCDNLEHKLNDLLKEKQSVERKCT 474
++N M+ + K+T D+ DL ++ VER+
Sbjct: 1626 GDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRAN 1685
Query: 475 QLNTKVAKLTNELKEEQEMNKCLRANQVLLQ-----NKLKEEERVLKETCDQKDLQITEI 529
L ++ +L L++ + K A Q LL L + L T + + I+++
Sbjct: 1686 LLQAEIEELRATLEQTERSRKI--AEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 530 QEQLRDVM 537
Q ++ D++
Sbjct: 1744 QGEMEDIL 1751
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/210 (28%), Positives = 93/210 (44%), Gaps = 42/210 (20%)
Query: 377 LVASKTDGKI-VQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEK--D 433
L+ K D ++ VQ E EG EE+ D QL +I E KI + + +
Sbjct: 886 LLKEKNDLQLQVQAEAEGLADAEERCD------------QLIKTKIQLEAKIKEVTERAE 933
Query: 434 TAEEINNMKTKFKETIE-KCDNLEHKLNDLL-------KEKQSVERKCTQLNTK------ 479
EEIN T K +E +C L+ ++DL KEK + E K L +
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 993
Query: 480 -VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMF 538
+AKLT E K QE A+Q L + EE++V T + ++++Q+ D+
Sbjct: 994 TIAKLTKEKKALQE------AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEG 1042
Query: 539 YLETQQKINHLPAETRQEIQEGQINIAMAS 568
LE ++K+ + E + EG + +A S
Sbjct: 1043 SLEQEKKL-RMDLERAKRKLEGDLKLAQES 1071
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/163 (23%), Positives = 79/163 (48%), Gaps = 17/163 (10%)
Query: 398 EEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEE----INNMKTKFKETIEKCD 453
E + + LQ E L + +++R KI E A E ++ T T +K +
Sbjct: 1681 ERRANLLQAEIEELRATLEQTER---SRKIAEQELLDASERVQLLHTQNTSLINTKKKLE 1737
Query: 454 N----LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLK 509
++ ++ D+L+E ++ E K + T A + ELK+EQ+ + L + ++ +K
Sbjct: 1738 TDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK 1797
Query: 510 EEERVLKETCDQKDL-----QITEIQEQLRDVMFYLETQQKIN 547
+ + L E +Q L QI +++ ++R++ +E++QK N
Sbjct: 1798 DLQLRLDE-AEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1839
Score = 39.3 bits (90), Expect = 0.010
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 370 GDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVR 429
G +H L K ++ Q +CE EE +L+ E +L QLE ++ E
Sbjct: 1525 GGKRIHEL--EKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582
Query: 430 IEKDTAEEINNMKTKFKETIEKCDN-LEHKL---NDLLKEKQSVERKCT----QLNTKVA 481
EKD EEI+ +K +E + L+ ++ ND ++ K+ +E QLN
Sbjct: 1583 AEKD--EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLE 541
L+ + L+ Q+ L + L+ +E LKE + + +Q ++ ++ LE
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQED-LKEQLAMVERRANLLQAEIEELRATLE 1699
Query: 542 TQQK 545
++
Sbjct: 1700 QTER 1703
Score = 38.9 bits (89), Expect = 0.013
Identities = 37/173 (21%), Positives = 74/173 (42%), Gaps = 18/173 (10%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEI---NNMKTKFKETIEKCDNLEHKLND 461
QL+ L SQL + + +I +++ EEI N + + + CD L + +
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 462 LLKEKQSVERKCTQLNTKVAKLTNELKEE--QEMNKCLRANQVLLQNKLKEEERV--LKE 517
+ K ++R ++ NT+VA+ + + + Q + A + L Q EE V +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 518 TCDQKDLQITEIQEQLRDVMFYLE-----------TQQKINHLPAETRQEIQE 559
C + +Q ++ D+M +E Q+ + + AE +Q+ +E
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Score = 37.0 bits (84), Expect = 0.051
Identities = 29/139 (20%), Positives = 67/139 (48%), Gaps = 16/139 (11%)
Query: 433 DTAEEINNMKTKFKETIEK--------CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLT 484
+ E+I+N++ + K+ +EK D+L + + K K ++E+ C L ++++L
Sbjct: 1208 ELGEQIDNLQ-RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266
Query: 485 NELKEEQEMNKCLRANQVLLQNK-------LKEEERVLKETCDQKDLQITEIQEQLRDVM 537
++ +E+Q + L A + LQ + L E+E ++ + K +I+E R +
Sbjct: 1267 SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLE 1326
Query: 538 FYLETQQKINHLPAETRQE 556
++ + + H +R +
Sbjct: 1327 EEIKAKNALAHALQSSRHD 1345
Score = 32.3 bits (72), Expect = 1.3
Identities = 32/168 (19%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Query: 381 KTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINN 440
+T K+ + + ++ +D LQ E + T L +I E ++ +E +E
Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT--LTKAKIKLEQQVDDLEGSLEQE-KK 1049
Query: 441 MKTKFKETIEKCDN----LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKC 496
++ + K + + + D+ EKQ ++ K + +++ L +++++EQ +
Sbjct: 1050 LRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQ 1109
Query: 497 LRANQVLLQNKLKE-EERVLKETCD--QKDLQITEIQEQLRDVMFYLE 541
L+ LQ +++E EE + E + + Q +++ +L ++ LE
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/132 (21%), Positives = 56/132 (42%)
Query: 405 QLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLK 464
Q+E + ++ + R E ++ E A E E+ DNL+ L K
Sbjct: 1166 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1225
Query: 465 EKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDL 524
EK ++ + L + V ++ ++M + L L++K +E++R++ + Q+
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285
Query: 525 QITEIQEQLRDV 536
TE E R +
Sbjct: 1286 LQTESGEFSRQL 1297
Score = 31.6 bits (70), Expect = 2.1
Identities = 38/188 (20%), Positives = 76/188 (40%), Gaps = 38/188 (20%)
Query: 378 VASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLES--QRIYWENKIVRIEKDTA 435
V S+ D KI + ++E+ID L+ + ++ S + I N +R++K
Sbjct: 1574 VKSEVDRKIAE--------KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1625
Query: 436 EEINNMKTKF---------------------KETIEKCDNLEHKLNDLLKEKQSVERKCT 474
++N M+ + K+T D+ DL ++ VER+
Sbjct: 1626 GDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRAN 1685
Query: 475 QLNTKVAKLTNELKEEQEMNKCLRANQVLLQ-----NKLKEEERVLKETCDQKDLQITEI 529
L ++ +L L++ + K A Q LL L + L T + + I+++
Sbjct: 1686 LLQAEIEELRATLEQTERSRKI--AEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 530 QEQLRDVM 537
Q ++ D++
Sbjct: 1744 QGEMEDIL 1751
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 5/186 (2%)
Query: 392 EGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEK 451
E T +E++ LQ E L +LE + K +I+ D AEE + + +
Sbjct: 508 ESLTAKEQRAAILQTEVD-ALRLRLEEKETMLNKKTKQIQ-DMAEEKGTQAGEIHDLKDM 565
Query: 452 CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEE 511
D E K+N L K+ ++++ + +++ L +K Q L+ L E+
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYL-ETQQKINHLPAETRQEIQEGQINIAMASAS 570
ER ++ +Q+D E QE++ + L + ++K++ L + + +E + AS
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE--KEASLLDLKEHAS 683
Query: 571 SPASSG 576
S ASSG
Sbjct: 684 SLASSG 689
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/156 (20%), Positives = 74/156 (47%), Gaps = 5/156 (3%)
Query: 425 NKIVRIEKDTA---EEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA 481
++I +E++ +E + + + +E +E++ ND K+ +ER+ N KVA
Sbjct: 735 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 794
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLE 541
L ++ + E++ + + ++ L + + L+++ +KD +I E++E LR+ +
Sbjct: 795 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITA 854
Query: 542 TQQKI--NHLPAETRQEIQEGQINIAMASASSPASS 575
++ + A T E Q ++ +AM S
Sbjct: 855 EREMVLAQEESARTNAEKQVEELLMAMEKVKQELES 890
Score = 38.5 bits (88), Expect = 0.018
Identities = 26/146 (17%), Positives = 75/146 (51%), Gaps = 8/146 (5%)
Query: 422 YWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA 481
+ +NK+ +++ EE+++ + +++E +K L+ ++ + +E + + L TK+
Sbjct: 435 FMKNKVEQLK----EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLE 490
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNK---LKEEERVLKETCDQKDLQITEIQEQLRDVMF 538
LTN+ + ++ + L+ + + + L+ E L+ ++K+ + + +Q++D+
Sbjct: 491 TLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE 550
Query: 539 YLETQQKINHLPAETRQEIQEGQINI 564
TQ H + +++E ++N+
Sbjct: 551 EKGTQAGEIH-DLKDMLDVKERKVNV 575
Score = 33.9 bits (76), Expect = 0.43
Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 8/111 (7%)
Query: 424 ENKIVRIEKDTAEEI--NNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA 481
EN ++R E E ++ KTK +T+ + + K++ + + + +E + L + A
Sbjct: 356 ENSMLREEMHRRFENAPDSAKTKALQTV--IEMKDSKISSMERGLRDLEEEIQMLKSNGA 413
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQ 532
T E +EE + + R++ ++NK+++ LKE K+ Q E++++
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKVEQ----LKEELSSKEAQWEELKKK 460
Score = 32.7 bits (73), Expect = 0.96
Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 10/97 (10%)
Query: 438 INNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCL 497
I +++T+ KE + + NDLL++ VE K ++L++ + + E + + L
Sbjct: 151 IMDLQTQLKEVLRE--------NDLLRK--DVEVKESKLSSSMNSIKTFWSPELKKERAL 200
Query: 498 RANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLR 534
R ++ KE+ RV++E + I +Q++LR
Sbjct: 201 RKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELR 237
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 5/186 (2%)
Query: 392 EGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEK 451
E T +E++ LQ E L +LE + K +I+ D AEE + + +
Sbjct: 480 ESLTAKEQRAAILQTEVD-ALRLRLEEKETMLNKKTKQIQ-DMAEEKGTQAGEIHDLKDM 537
Query: 452 CDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEE 511
D E K+N L K+ ++++ + +++ L +K Q L+ L E+
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 597
Query: 512 ERVLKETCDQKDLQITEIQEQLRDVMFYL-ETQQKINHLPAETRQEIQEGQINIAMASAS 570
ER ++ +Q+D E QE++ + L + ++K++ L + + +E + AS
Sbjct: 598 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE--KEASLLDLKEHAS 655
Query: 571 SPASSG 576
S ASSG
Sbjct: 656 SLASSG 661
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/156 (20%), Positives = 74/156 (47%), Gaps = 5/156 (3%)
Query: 425 NKIVRIEKDTA---EEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA 481
++I +E++ +E + + + +E +E++ ND K+ +ER+ N KVA
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 766
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLE 541
L ++ + E++ + + ++ L + + L+++ +KD +I E++E LR+ +
Sbjct: 767 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITA 826
Query: 542 TQQKI--NHLPAETRQEIQEGQINIAMASASSPASS 575
++ + A T E Q ++ +AM S
Sbjct: 827 EREMVLAQEESARTNAEKQVEELLMAMEKVKQELES 862
Score = 33.5 bits (75), Expect = 0.56
Identities = 25/112 (22%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 424 ENKIVRIEKDTAEEI--NNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVA 481
EN ++R E E ++ KTK +T+ + + K++ + + + +E + L + A
Sbjct: 356 ENSMLREEMHRRFENAPDSAKTKALQTV--IEMKDSKISSMERGLRDLEEEIQMLKSNGA 413
Query: 482 KLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQL 533
T E +EE + + R++ ++NK+ + +K+ +KD ++ +Q +L
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKIGQ----VKQELSRKDTELLALQTKL 461
Score = 32.7 bits (73), Expect = 0.96
Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 10/97 (10%)
Query: 438 INNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCL 497
I +++T+ KE + + NDLL++ VE K ++L++ + + E + + L
Sbjct: 151 IMDLQTQLKEVLRE--------NDLLRK--DVEVKESKLSSSMNSIKTFWSPELKKERAL 200
Query: 498 RANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLR 534
R ++ KE+ RV++E + I +Q++LR
Sbjct: 201 RKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELR 237
Score = 32.7 bits (73), Expect = 0.96
Identities = 45/212 (21%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 373 YVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEK 432
+VH L + + Q E E +EE + T L++ ++KI +E+
Sbjct: 342 HVHHL-----ESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMER 396
Query: 433 ---DTAEEINNMKTK----FKETIEKCDNLE-------HKLNDLLKEKQSVERKCTQL-- 476
D EEI +K+ +E E+ +E N + + KQ + RK T+L
Sbjct: 397 GLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLA 456
Query: 477 -NTKVAKLTNELKEEQEMNKCLRANQVLLQNK---LKEEERVLKETCDQKDLQITEIQEQ 532
TK+ LTN+ + ++ + L+ + + + L+ E L+ ++K+ + + +Q
Sbjct: 457 LQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 516
Query: 533 LRDVMFYLETQQKINHLPAETRQEIQEGQINI 564
++D+ TQ H + +++E ++N+
Sbjct: 517 IQDMAEEKGTQAGEIH-DLKDMLDVKERKVNV 547
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 19/166 (11%)
Query: 395 TCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDN 454
T E+K+ L + S ES R E KI EK+ EE++ + F+ ++C
Sbjct: 358 TALEQKLKKLTEDLS-CQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ 416
Query: 455 LEHKLNDLLKEKQS----VERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKE 510
++ +L L++ ++ ++ + +L + +L N L+E ++ K RA Q +++KE
Sbjct: 417 MKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ--KLCRAEQAFQASQIKE 474
Query: 511 ------------EERVLKETCDQKDLQITEIQEQLRDVMFYLETQQ 544
E +LK +QK ++ ++ +L+++ L Q
Sbjct: 475 NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ 520
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/222 (24%), Positives = 92/222 (41%), Gaps = 47/222 (21%)
Query: 395 TCQEEKIDALQLEYSYLLTSQLE-------SQRIYWENKIVRIEKDTAEEINNMKT---- 443
T +EE + + +LE L +S+ E + +I E K + + D + +N +K
Sbjct: 2733 TSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELK--KTKMDNLKYVNQLKKENER 2790
Query: 444 ---KFKETIEKCDNLEHKLNDLLKE------KQSVERKCTQLNTKVAKLTNELKEEQEMN 494
K K I+ C LE + L KE Q ++ T ++TKV +LT E+KE +E
Sbjct: 2791 AQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKE-- 2848
Query: 495 KCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETR 554
L+ K KE + L + C + E+L LETQ + HL ++
Sbjct: 2849 --------TLEEKTKEADEYLDKYC-----SLLISHEKLEKAKEMLETQ--VAHLCSQQS 2893
Query: 555 QEIQEGQINIA--------MASASSPASSGGSGKLPSRKGRS 588
++ G + + S + S G K ++ RS
Sbjct: 2894 KQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQRS 2935
Score = 38.1 bits (87), Expect = 0.023
Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 31/193 (16%)
Query: 412 LTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVER 471
L QL++Q NKI +E MK + + E LE +L+ EK+ V
Sbjct: 279 LLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI-EKEKVLN 337
Query: 472 KCT-----------QLNTKVAKLTNELKEEQEMNKCLRAN----QVLLQNKLKEEER--- 513
KC Q +TK L +LK+ E C R N + L+ K+KE+E+
Sbjct: 338 KCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQ 397
Query: 514 -----------VLKETCDQKDLQITEIQEQLRDVMFYLETQ-QKINHLPAETRQEIQEGQ 561
L + C Q ++T+ +Q +++ L+ + K+ + + ++E +
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 562 INIAMASASSPAS 574
+ A + AS
Sbjct: 458 QKLCRAEQAFQAS 470
Score = 37.4 bits (85), Expect = 0.039
Identities = 37/171 (21%), Positives = 83/171 (48%), Gaps = 27/171 (15%)
Query: 414 SQLESQRIYWENKIVRIEK--DTAEEINNMKTKFKETIEK----------CDNL-EHKLN 460
S+L Q Y + K++ +++ +T ++ K+K EK C +L E++ N
Sbjct: 1012 SELSDQ--YKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKN 1069
Query: 461 DLLKEKQSVERKCTQLNTKVA----KLTNELKEEQEMNKCLRANQVLLQNK-------LK 509
+L + K++ ++ + TK+A + N + E + + + LR+ QN LK
Sbjct: 1070 ELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLK 1129
Query: 510 EEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAE-TRQEIQE 559
+E LKE ++ ++ ++ ++ +M ++T+ + +L +E R ++E
Sbjct: 1130 QEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKE 1180
Score = 37.0 bits (84), Expect = 0.051
Identities = 45/213 (21%), Positives = 95/213 (44%), Gaps = 22/213 (10%)
Query: 363 HRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIY 422
H++W N R + + + KI + + + Q+ ++ LQ Y L ++LE ++
Sbjct: 2548 HQLWKE--QNLELRNLTVELEQKIQVLQSKNASLQDT-LEVLQSSYKNL-ENELELTKMD 2603
Query: 423 WENKIVRIEKDTAEEIN---NMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK 479
+ + ++ K TA+E M ++T E + L + N L E Q + + +
Sbjct: 2604 KMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQ 2663
Query: 480 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEE---------------ERVLKETCDQKDL 524
+ +LT E E ++ C+ +QV + K++EE + +L +T Q ++
Sbjct: 2664 LKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEV 2723
Query: 525 QITEIQEQLRDVMFYLETQQKINHLPAETRQEI 557
+I +E+L L +Q+ L +++E+
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEEL 2756
Score = 34.7 bits (78), Expect = 0.25
Identities = 32/122 (26%), Positives = 64/122 (52%), Gaps = 6/122 (4%)
Query: 428 VRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVE--RKCTQLNTKVAKLTN 485
VRIE D ++++ + K KE + D+L+ K+ +L +E Q E ++ L+ + +K
Sbjct: 2126 VRIEADEKKQLH-IAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEV 2184
Query: 486 ELKEEQ--EMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQ 543
E + Q EM + L+ ++ L E+E + K+ +K Q++E+ + L LE +
Sbjct: 2185 ETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQ-IQEKQGQLSELDKLLSSFKSLLEEK 2243
Query: 544 QK 545
++
Sbjct: 2244 EQ 2245
Score = 33.9 bits (76), Expect = 0.43
Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 16/107 (14%)
Query: 436 EEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNK 495
E+I+N++ + KET + L H + D ++ +S+ + +L++K+ L+E Q M K
Sbjct: 1767 EDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKL-----HLQEVQLMTK 1821
Query: 496 ---CLRANQVLLQNKLKEEERVLKE-----TCDQKD-LQITEIQEQL 533
C+ +++ +LK+E L E +CD ++ LQ E E L
Sbjct: 1822 IEACIELEKIV--GELKKENSDLSEKLEYFSCDHQELLQRVETSEGL 1866
Score = 33.9 bits (76), Expect = 0.43
Identities = 19/84 (22%), Positives = 43/84 (51%)
Query: 453 DNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEE 512
+ L+ K+ + + + +E + ++ LTNEL++EQE L +N L+E+E
Sbjct: 2367 ETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKE 2426
Query: 513 RVLKETCDQKDLQITEIQEQLRDV 536
+ + ++ + +Q QL+++
Sbjct: 2427 QEKVQMKEKSSTAMEMLQTQLKEL 2450
Score = 33.5 bits (75), Expect = 0.56
Identities = 22/115 (19%), Positives = 57/115 (49%), Gaps = 7/115 (6%)
Query: 451 KCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKE 510
+ D+LE L + ++++C +L ++ L + ++M++ A +KL+E
Sbjct: 831 RVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQE 890
Query: 511 E----ERVLKET---CDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQ 558
+ + V+ ET + K+ ++ + +++ ++ +K NHL ++ +E+Q
Sbjct: 891 DTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQ 945
Score = 32.7 bits (73), Expect = 0.96
Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 22/155 (14%)
Query: 415 QLESQRIYW---ENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVER 471
++E+Q++ + + K ++ +EI NM K + + ++LEHKL L E +R
Sbjct: 692 EVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDR 751
Query: 472 KCTQLNTKVAKLTNELK-------------------EEQEMNKCLRANQVLLQNKLKEEE 512
L+ + L + LK ++Q AN + Q + E
Sbjct: 752 CYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSER 811
Query: 513 RVLKETCDQKDLQITEIQEQLRDVMFYLETQQKIN 547
+ DQ +Q ++ + F LE+Q+++N
Sbjct: 812 SECRLEADQSPKNSAILQNRVDSLEFSLESQKQMN 846
Score = 32.7 bits (73), Expect = 0.96
Identities = 31/144 (21%), Positives = 70/144 (48%), Gaps = 13/144 (9%)
Query: 398 EEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDT---AEEINNMKTKFKETIEKCDN 454
+EK+ +L+ + L ++ E EN+I ++ K+ +E +++ + E+ + N
Sbjct: 2034 QEKLQSLEKDSQALSLTKCEL-----ENQIAQLNKEKELLVKESESLQARLSESDYEKLN 2088
Query: 455 LEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEER- 513
+ L L EK + + +V +L +++ + + Q+ + KLKE ER
Sbjct: 2089 VSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2148
Query: 514 --VLKETCD--QKDLQITEIQEQL 533
LK+ + +++LQ++E ++L
Sbjct: 2149 NDSLKDKVENLERELQMSEENQEL 2172
Score = 32.3 bits (72), Expect = 1.3
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 16/139 (11%)
Query: 414 SQLESQRIYWEN--KIVRIEKDTAEEINNMKTKFKETIEK-CDNLEHKLNDLLKEKQSVE 470
+ +E + +Y E ++V+ EK E+ N K K +E+ + + N L E ++
Sbjct: 1912 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMS 1971
Query: 471 RKCT---QLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQIT 527
+K T QL+ K+ + T EL+ Q ++CL QV E +KE + +
Sbjct: 1972 KKTTALDQLSEKMKEKTQELESHQ--SECLHCIQVA--------EAEVKEKTELLQTLSS 2021
Query: 528 EIQEQLRDVMFYLETQQKI 546
++ E L+D E Q +
Sbjct: 2022 DVSELLKDKTHLQEKLQSL 2040
Score = 32.3 bits (72), Expect = 1.3
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 22/156 (14%)
Query: 385 KIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTK 444
K+ + E E D+ ++ K++ L+ E L E+Q + ++ +++ E+ +KT+
Sbjct: 2141 KLKERERENDSLKD-KVENLERE----LQMSEENQEL-----VILDAENSKAEVETLKTQ 2190
Query: 445 FKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLT------NELKEEQE-----M 493
+E E L L EK+++ ++ + ++++L L EE+E +
Sbjct: 2191 IEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQI 2250
Query: 494 NKCLRANQVLLQNKLKEEERVLKETC-DQKDLQITE 528
+ + +LQN+LKE + C DQ+ ++ TE
Sbjct: 2251 KEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATE 2286
Score = 30.8 bits (68), Expect = 3.7
Identities = 44/223 (19%), Positives = 92/223 (41%), Gaps = 39/223 (17%)
Query: 344 HAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDA 403
H+ + E H A +L N + N+ + A T + + + + Q+E ++
Sbjct: 494 HSEQKAREVCHLEA-ELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQE--NS 550
Query: 404 LQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLL 463
L LE L + LE QR D ++++ ++K ++ +LND L
Sbjct: 551 LTLEKLKLAVADLEKQR------------DCSQDL----------LKKREHHIEQLNDKL 588
Query: 464 KEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKD 523
+ + + K ELKEE+ + C ++ E E++L + +K+
Sbjct: 589 SKTEKESKALLSALELKKKEYEELKEEKTLFSCWKS----------ENEKLLTQMESEKE 638
Query: 524 LQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAM 566
+Q ++ + L+TQQ +H E + ++ + N+++
Sbjct: 639 ----NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSV 677
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,494,556
Number of Sequences: 37866
Number of extensions: 1027108
Number of successful extensions: 7003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 634
Number of HSP's that attempted gapping in prelim test: 5102
Number of HSP's gapped (non-prelim): 2219
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.