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Search of human proteins with 187960055
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187960055 G protein-coupled receptor 52 [Homo sapiens]
(361 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187960055 G protein-coupled receptor 52 [Homo sapiens] 752 0.0
gi|4885307 G protein-coupled receptor 21 [Homo sapiens] 481 e-136
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 106 4e-23
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 106 4e-23
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 100 2e-21
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 95 1e-19
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 95 1e-19
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 91 1e-18
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 90 4e-18
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 90 4e-18
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 90 4e-18
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 90 4e-18
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 90 4e-18
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 90 4e-18
gi|222080109 orexin receptor 2 [Homo sapiens] 87 2e-17
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 87 2e-17
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 84 3e-16
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] 83 4e-16
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 82 6e-16
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 82 7e-16
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 80 2e-15
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 80 2e-15
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 80 2e-15
gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens] 79 5e-15
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 79 5e-15
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 79 6e-15
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 79 6e-15
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 79 6e-15
gi|4557857 somatostatin receptor 1 [Homo sapiens] 79 6e-15
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 79 8e-15
>gi|187960055 G protein-coupled receptor 52 [Homo sapiens]
Length = 361
Score = 752 bits (1941), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT 60
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
Sbjct: 1 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT 60
Query: 61 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI 120
VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
Sbjct: 61 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI 120
Query: 121 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW 180
ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
Sbjct: 121 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW 180
Query: 181 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR 240
GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
Sbjct: 181 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR 240
Query: 241 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF 300
RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
Sbjct: 241 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF 300
Query: 301 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
Sbjct: 301 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
Query: 361 I 361
I
Sbjct: 361 I 361
>gi|4885307 G protein-coupled receptor 21 [Homo sapiens]
Length = 349
Score = 481 bits (1237), Expect = e-136
Identities = 228/320 (71%), Positives = 268/320 (83%), Gaps = 1/320 (0%)
Query: 20 NVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYF 79
N S C L FG+ V+ C+ E ++IV LT LII+GN+ VIFVFHCAPLL+H+TTSYF
Sbjct: 8 NQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYF 67
Query: 80 IQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDR 139
IQTMAYADLFVGVSC+VP+LSLLH+ V ESLTCQ+FG+++SVLKSVSMA LACIS+DR
Sbjct: 68 IQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDR 127
Query: 140 YLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLT 199
Y+AITKPL+YN LVTP RLR+CI LIW+YS L+FLPSFF WGKPGYHGD+F+WCA SW T
Sbjct: 128 YIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHT 187
Query: 200 SAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSP 259
+YFT FIV +LYAPAA +VCFTYF+IF+IC+QHTK+I++R+ARF S ++ E P
Sbjct: 188 DSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETG-EVQACP 246
Query: 260 DRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSL 319
D+RYAMVLFRITSVFY+LWLPYIIYFLLESS N SFLTTWLAISNSFCNCVIYSL
Sbjct: 247 DKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSL 306
Query: 320 SNSVFRLGLRRLSETMCTSC 339
SNSVF+ GL+RLS MCTSC
Sbjct: 307 SNSVFQRGLKRLSGAMCTSC 326
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 106 bits (264), Expect = 4e-23
Identities = 86/298 (28%), Positives = 133/298 (44%), Gaps = 27/298 (9%)
Query: 44 TVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLH 103
TVV+ +L + +AGN+ V L + T FI ++A DL +G+ LV S ++
Sbjct: 22 TVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC-FIVSLAITDLLLGL--LVLPFSAIY 78
Query: 104 -----YSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRL 158
+S G + C ++ + +L + S+ L IS+DRY A+ PL Y LVTP R+
Sbjct: 79 QLSCKWSFG---KVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRV 135
Query: 159 RICIILIWIYS-CLIFLPSFFGWGKPG--YHGDIFEWCATSWLTSAYFTGFIVCLLYAPA 215
I ++LIW+ S L FL GW G+ + Y + Y P
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLP- 194
Query: 216 AFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFY 275
++C TY+ IFK+ R K IN SS + + + + L + F
Sbjct: 195 LLIMCITYYRIFKVARDQAKRINH----------ISSWKAATIREHKATVTLAAVMGAFI 244
Query: 276 MLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRL 331
+ W PY F+ R D N L + WL +NS N ++Y+ N FR G ++L
Sbjct: 245 ICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQL 302
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 106 bits (264), Expect = 4e-23
Identities = 86/298 (28%), Positives = 133/298 (44%), Gaps = 27/298 (9%)
Query: 44 TVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLH 103
TVV+ +L + +AGN+ V L + T FI ++A DL +G+ LV S ++
Sbjct: 22 TVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC-FIVSLAITDLLLGL--LVLPFSAIY 78
Query: 104 -----YSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRL 158
+S G + C ++ + +L + S+ L IS+DRY A+ PL Y LVTP R+
Sbjct: 79 QLSCKWSFG---KVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRV 135
Query: 159 RICIILIWIYS-CLIFLPSFFGWGKPG--YHGDIFEWCATSWLTSAYFTGFIVCLLYAPA 215
I ++LIW+ S L FL GW G+ + Y + Y P
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLP- 194
Query: 216 AFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFY 275
++C TY+ IFK+ R K IN SS + + + + L + F
Sbjct: 195 LLIMCITYYRIFKVARDQAKRINH----------ISSWKAATIREHKATVTLAAVMGAFI 244
Query: 276 MLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRL 331
+ W PY F+ R D N L + WL +NS N ++Y+ N FR G ++L
Sbjct: 245 ICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQL 302
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 100 bits (250), Expect = 2e-21
Identities = 83/346 (23%), Positives = 150/346 (43%), Gaps = 41/346 (11%)
Query: 39 VCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSY-FIQTMAYADLFVGVSCLVP 97
V I + + I+++T + GNL ++ + L + + F T++ L V V V
Sbjct: 26 VIITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVV 85
Query: 98 TLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCR 157
T S+ + + C + ++ S SM L I++DRY A+ P+ Y +T R
Sbjct: 86 TSSIRR--EWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNR 143
Query: 158 LRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEW-CATSWLTSAYFTGF--IVCLLYAP 214
+ ++ IW++S + LP FGW + D F+W C +W +T F I C L+
Sbjct: 144 AVMALVYIWLHSLIGCLPPLFGWSSVEF--DEFKWMCVAAWHREPGYTAFWQIWCALFPF 201
Query: 215 AAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV------DSSRETGHSPDRRYA---- 264
+VC+ + IF++ R ++++ + +SS T S RR A
Sbjct: 202 LVMLVCYGF--IFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGV 259
Query: 265 ----------MVLFRITSVFYMLWLPYIIYFLLES--SRVLDNPTLSFLTTWLAISNSFC 312
+ + + F + W PY++ E+ + +P+L TWL+ +++ C
Sbjct: 260 VYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVC 319
Query: 313 NCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANS 358
+ +IY L N R L MC D+ +EP +++ S
Sbjct: 320 HPLIYGLWNKTVRKELLG---------MCFGDRYYREPFVQRQRTS 356
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 94.7 bits (234), Expect = 1e-19
Identities = 85/326 (26%), Positives = 137/326 (42%), Gaps = 49/326 (15%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLL--- 102
++ L + GNL VI P L T + F+ ++A ADL +G+ + P +L
Sbjct: 43 LLALAVLATVGGNLLVIVAIAWTPRLQTMT-NVFVTSLAAADLVMGLLVVPPAATLALTG 101
Query: 103 HYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICI 162
H+ G + C+++ + + + S+ L ++VDRYLA+T PL Y LVT R +
Sbjct: 102 HWPLG---ATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAV 158
Query: 163 ILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAF---- 217
+L+W+ S + F P W + G + + C ++ A+ + LL + +F
Sbjct: 159 VLVWVVSAAVSFAPIMSQWWRVGADAEA-QRCHSNPRCCAFASNMPYVLLSSSVSFYLPL 217
Query: 218 -VVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSP----------------- 259
V+ F Y +F + + + + RFP E + +P
Sbjct: 218 LVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGR 277
Query: 260 ---------DRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTL----SFLT-TWL 305
+ R L I F + WLP +FL R L P+L +FL WL
Sbjct: 278 RPARLLPLREHRALCTLGLIMGTFTLCWLP---FFLANVLRALGGPSLVPGPAFLALNWL 334
Query: 306 AISNSFCNCVIYSLSNSVFRLGLRRL 331
+NS N +IY S FR RRL
Sbjct: 335 GYANSAFNPLIYCRSPD-FRSAFRRL 359
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 94.7 bits (234), Expect = 1e-19
Identities = 81/307 (26%), Positives = 134/307 (43%), Gaps = 25/307 (8%)
Query: 45 VVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHY 104
+V+ L+ I+ GN+ VI L T+YFI ++A ADL +G++ + + +
Sbjct: 38 IVMSLIVLAIVFGNVLVITAIAKFERLQT-VTNYFITSLACADLVMGLAVVPFGAAHILM 96
Query: 105 STGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIL 164
+ C+ + I + + S+ L I+VDRY AIT P Y L+T + R+ I++
Sbjct: 97 KMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILM 156
Query: 165 IWIYSCLI-FLPSFFGWGKPGYHGDI----FEWCATSWLTSAYFTGFIVCLLYAPAAFVV 219
+WI S L FLP W + + I E C + AY + Y P +V
Sbjct: 157 VWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMV 216
Query: 220 CFTYFHIFKICRQHTKEINDRRARFPSH---EVDSSRETGHS---------PDRRYAMVL 267
F Y +F+ ++ ++I+ RF +V+ TGH + + L
Sbjct: 217 -FVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTL 275
Query: 268 FRITSVFYMLWLPYIIYFLLESSRVLDN---PTLSFLTTWLAISNSFCNCVIYSLSNSVF 324
I F + WLP+ I ++ + DN + L W+ NS N +IY S F
Sbjct: 276 GIIMGTFTLCWLPFFIVNIVHV--IQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPD-F 332
Query: 325 RLGLRRL 331
R+ + L
Sbjct: 333 RIAFQEL 339
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 91.3 bits (225), Expect = 1e-18
Identities = 88/359 (24%), Positives = 152/359 (42%), Gaps = 48/359 (13%)
Query: 37 VDVCIFETVVIVLLTFLIIA--GNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSC 94
+D+ +V +VL F++ A GN+ VI C L T+YFI +A ADL + +
Sbjct: 40 LDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTV 98
Query: 95 LVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVT 154
L + +L V + C ++ + + + S+ L IS+DRY+ + L Y LVT
Sbjct: 99 LPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVT 158
Query: 155 PCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCL--LY 212
+ + ++ +W+ S +I + GW +P + D + C +T F L Y
Sbjct: 159 RRKAILALLSVWVLSTVISIGPLLGWKEPAPNDD--KECG---VTEEPFYALFSSLGSFY 213
Query: 213 APAAFVVCFTYFHIFKICRQHTKEI---------NDRRARFPSHE-------VDSSRETG 256
P A V+ Y ++ + ++ TK + N + H + S++ G
Sbjct: 214 IPLA-VILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKG 272
Query: 257 HSPDRRYAMVLFR-------------ITSVFYMLWLPYIIYFLLES-SRVLDNPTLSF-L 301
H+P A+ LF+ + +F + WLP+ I L S L P F +
Sbjct: 273 HNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKV 332
Query: 302 TTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
WL NS N +IY S+ F+ R+ C C + + + + R+R C+
Sbjct: 333 VFWLGYFNSCLNPIIYPCSSKEFKRAFVRI-----LGCQC-RGRGRRRRRRRRRLGGCA 385
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 89.7 bits (221), Expect = 4e-18
Identities = 92/350 (26%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFI 207
Y +TP R+ + + W+ I FLP GW G D+ E + +++ + F+
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIEKRKFNQNSNSTYCVFM 187
Query: 208 VCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHS 258
V YA VV F Y+ I+ ++H +I + S E HS
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 259 PDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNS 310
R + A L I F + W P+ + +++ V +FL WL NS
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL--WLGYINS 305
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS 360
N +Y+ N FR + +C D+ + P + CS
Sbjct: 306 GLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQTVPCS 347
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 87.4 bits (215), Expect = 2e-17
Identities = 93/347 (26%), Positives = 144/347 (41%), Gaps = 55/347 (15%)
Query: 52 FLIIAGNLTVIFVFHCAPLL--------HHY--TTSYFIQTMAYADLFVGVSCLVPTLSL 101
+++IAG + V V +L HH T+YFI ++ AD+ V ++CL TL +
Sbjct: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
Query: 102 LHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRIC 161
T C+V Y+ +V SVS+ L+CI++DR+ AI PL + T R R
Sbjct: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKS--TAKRARNS 172
Query: 162 IILIWIYSCLIFLPSFF----GWGKPGYHG--DIFEWCATSWLTSAYFTGFIVC---LLY 212
I++IWI SC+I +P PG +F C W Y + +C + Y
Sbjct: 173 IVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTY 232
Query: 213 APAAFVVCFTYFHIFK--ICRQ--HTKEINDRRARFPSHEVDSSRETGHSPD-------- 260
++ Y IF+ CRQ T + R+ + P V R G
Sbjct: 233 MAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWK-PLQPVSQPRGPGQPTKSRMSAVAA 291
Query: 261 --------RRYAMVLFRITSVFYMLWLPYIIYFLLES-----SRVLDNPTLSFLTT---W 304
R+ A +L + VF + +LP I +L+ + D T+ T W
Sbjct: 292 EIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHW 351
Query: 305 LAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPK 351
L +NS N +IY+ + FR + SC C+ QE +
Sbjct: 352 LVYANSAANPIIYNFLSGKFREEFK-----AAFSCCCLGVHHRQEDR 393
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 87.4 bits (215), Expect = 2e-17
Identities = 91/361 (25%), Positives = 151/361 (41%), Gaps = 55/361 (15%)
Query: 45 VVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHY 104
+++ L+ LI+AGN+ VI P L T + FI ++A ADL +G+ + +++ +
Sbjct: 63 LLMALIVLLIVAGNVLVIVAIAKTPRLQTLT-NLFIMSLASADLVMGLLVVPFGATIVVW 121
Query: 105 STGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIL 164
+ S C+++ + + + S+ L I++DRYLAIT P Y L+T R R +
Sbjct: 122 GRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCT 181
Query: 165 IWIYSCLI-FLPSFFGWGKPGYHGDIFEWC-----ATSWLTS-AYFTGFIVCLLYAPAAF 217
+W S L+ FLP W + D C ++T+ AY V Y P
Sbjct: 182 VWAISALVSFLPILMHWWRA--ESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLC- 238
Query: 218 VVCFTYFHIFKICRQHTKEINDRRARF-------PSHE---------------------- 248
++ F Y +F+ ++ K+I+ RF PS
Sbjct: 239 IMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAAT 298
Query: 249 --VDSSRETGHSPDRRYAM-------VLFRITSVFYMLWLPYIIYFLLES-SRVLDNPTL 298
+ + R P R A+ L I VF + WLP+ + ++++ R L L
Sbjct: 299 APLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRL 358
Query: 299 SFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANS 358
WL +NS N +IY S FR + L +C + + + A R RA+
Sbjct: 359 FVFFNWLGYANSAFNPIIYCRSPD-FRKAFQGL---LCCARRAARRRHATH-GDRPRASG 413
Query: 359 C 359
C
Sbjct: 414 C 414
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 83.6 bits (205), Expect = 3e-16
Identities = 83/332 (25%), Positives = 138/332 (41%), Gaps = 30/332 (9%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYS 105
V++ LT A N +I + P L + T+++F+ ++ +DL VG+ + P + Y
Sbjct: 35 VVIALT---AAANSLLIALICTQPALRN-TSNFFLVSLFTSDLMVGLVVMPPAMLNALYG 90
Query: 106 TGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILI 165
V C ++ + S S+ L IS+DRYL I PL Y +TP R ++
Sbjct: 91 RWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGA 150
Query: 166 WIYSCLI-FLPSFFGWGKPGY-HGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTY 223
W + L FLP GW + G+ + C L S F L + + +CFTY
Sbjct: 151 WSLAALASFLPLLLGWHELGHARPPVPGQCRL--LASLPFVLVASGLTFFLPSGAICFTY 208
Query: 224 FHIFKICR---------------QHTKEINDRRARFPSHEVDSSRETGHSPDR---RYAM 265
I R Q ++ + R P E SR R + ++
Sbjct: 209 CRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASL 268
Query: 266 VLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFR 325
L + +F++ WLP+ + ++++ +P L + TWL NS N +IY L F+
Sbjct: 269 TLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFK 328
Query: 326 LGLRRLSETMCTSCMCVKDQEAQEPKPRKRAN 357
L R C ++++A P R +
Sbjct: 329 RALGR----FLPCPRCPRERQASLASPSLRTS 356
>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
Length = 318
Score = 82.8 bits (203), Expect = 4e-16
Identities = 79/290 (27%), Positives = 127/290 (43%), Gaps = 31/290 (10%)
Query: 48 VLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG 107
+ + I GN+ VI V P L TT YFI ++A AD+ VGV ++P ++
Sbjct: 20 IFIGLCAIVGNVLVICVVKLNPSLQT-TTFYFIVSLALADIAVGV-LVMPLAIVVSLGIT 77
Query: 108 VHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWI 167
+H +C ++ + S+ L I+VDRYL + + Y ++ T R+ + + L W+
Sbjct: 78 IH-FYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWL 136
Query: 168 YSCLIFLPSFFGWG---KPGYHGDI-FEWCA-TSWLTSAYFTGFIVCLLYAPAAFVVCFT 222
S L+ L FGW YH ++ F C S + Y F V+C
Sbjct: 137 VSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAI 196
Query: 223 YFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRY--AMVLFRITSVFYMLWLP 280
Y IF I R S + +S+ETG R + A LF + +F + WLP
Sbjct: 197 YLDIFYIIRNKL-----------SLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLP 245
Query: 281 Y-----IIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFR 325
IIYF E ++ + ++ L+ +NS N ++Y+ F+
Sbjct: 246 LSIINCIIYFNGEVPQL-----VLYMGILLSHANSMMNPIVYAYKIKKFK 290
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 82.4 bits (202), Expect = 6e-16
Identities = 69/318 (21%), Positives = 141/318 (44%), Gaps = 13/318 (4%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYS 105
VI+L+ + GNLTVI+ F C + FI +A +D + + + Y
Sbjct: 76 VILLVGLTGMLGNLTVIYTF-CRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYK 134
Query: 106 TGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILI 165
+ C+ + + ++ SM L I++DRYL IT+PL+ + + R ++ +
Sbjct: 135 QWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGV 194
Query: 166 WIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSA----YFTGFIVCLLYAPAAFVVCF 221
W+Y+ LP FFGW G + C+ +++ +T + C ++ ++ +
Sbjct: 195 WLYALAWSLPPFFGWSAYVPEG-LLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIY 253
Query: 222 TYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPY 281
Y IF+ R+ + + A + E R+ S + + A ++ + +F + W PY
Sbjct: 254 CYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQS-ECKMAKIMLLVILLFVLSWAPY 312
Query: 282 IIYFLLE---SSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTS 338
L+ + VL P +S + +A +++ N +IY++++ +R+ + + C
Sbjct: 313 SAVALVAFAGYAHVL-TPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQ--HLPCLG 369
Query: 339 CMCVKDQEAQEPKPRKRA 356
+ + P P R+
Sbjct: 370 VLLGVSRRHSRPYPSYRS 387
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 82.0 bits (201), Expect = 7e-16
Identities = 92/365 (25%), Positives = 144/365 (39%), Gaps = 50/365 (13%)
Query: 30 GFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLF 89
GFG V + F + VI++ I GNL V+ L T+YFI ++A+ADL
Sbjct: 13 GFGSVEKVVLLTFLSTVILMA----ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL 68
Query: 90 VGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAI-TKPLS 148
V V + L ++ + C V + +L + S+ L CIS+DRY AI +PL
Sbjct: 69 VSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128
Query: 149 YNQLVTPCRLRICIILIWIYSCLI-FLPSFFGWGKPG---------------YHGDIFEW 192
Y +TP R+ + + W+ I FLP GW G +H E
Sbjct: 129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHA--IEK 186
Query: 193 CATSWLTSAYFTGFIVCLLYAPAAFVVCF---------TYFHIFKICRQHTKEINDRRAR 243
+ +++ + F+V YA VV F Y+ I+ ++H +I +
Sbjct: 187 RKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRA 246
Query: 244 FPSHEVDSSRETGHSPDR-----RYAMVLFRITSVFYMLWLPYIIYFLLE---SSRVLDN 295
S E HS R + A L I F + W P+ + +++ V
Sbjct: 247 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 306
Query: 296 PTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKR 355
+FL WL NS N +Y+ N FR + +C D+ + P +
Sbjct: 307 VWTAFL--WLGYINSGLNPFLYAFLNKSFRRAFLII--------LCCDDERYRRPSILGQ 356
Query: 356 ANSCS 360
CS
Sbjct: 357 TVPCS 361
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 80.5 bits (197), Expect = 2e-15
Identities = 71/329 (21%), Positives = 144/329 (43%), Gaps = 24/329 (7%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTT-----------SYFIQTMAYADLFVGVSC 94
VI+L+ + GNLTVI+ F C +L T + FI +A +D + +
Sbjct: 76 VILLVGLTGMLGNLTVIYTF-CRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQ 134
Query: 95 LVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVT 154
+ Y + C+ + + ++ SM L I++DRYL IT+PL+ + +
Sbjct: 135 APVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVAS 194
Query: 155 PCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSA----YFTGFIVCL 210
R ++ +W+Y+ LP FFGW G + C+ +++ +T + C
Sbjct: 195 KRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEG-LLTSCSWDYMSFTPAVRAYTMLLCCF 253
Query: 211 LYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRI 270
++ ++ + Y IF+ R+ + + A + E R+ S + + A ++ +
Sbjct: 254 VFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQS-ECKMAKIMLLV 312
Query: 271 TSVFYMLWLPYIIYFLLE---SSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLG 327
+F + W PY L+ + VL P +S + +A +++ N +IY++++ +R+
Sbjct: 313 ILLFVLSWAPYSAVALVAFAGYAHVL-TPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA 371
Query: 328 LRRLSETMCTSCMCVKDQEAQEPKPRKRA 356
+ + C + + P P R+
Sbjct: 372 IAQ--HLPCLGVLLGVSRRHSRPYPSYRS 398
>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
sapiens]
Length = 306
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 33/292 (11%)
Query: 52 FLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHES 111
F+ I GNL +I LH T++ I +MA D +G + ++P + +
Sbjct: 10 FITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFT-IMPYSMIRSVENCWYFG 67
Query: 112 LT-CQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIW---- 166
LT C+++ +L S+ L +++DR+ AI PL Y+ +T ++ ++L W
Sbjct: 68 LTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPG 127
Query: 167 IYSCLIFLPSFFGWGKPGYHGDIFEWCATS--------WLTSAYFTGFIVCLLYAPAAFV 218
++ + + G GY DI C++S W T+ + GF + P + +
Sbjct: 128 AFAFGVVFSEAYADGIEGY--DILVACSSSCPVMFNKLWGTTLFMAGF-----FTPGSMM 180
Query: 219 VCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLW 278
V Y IF + R+H IN+ R ++ D++ A L + VF + W
Sbjct: 181 VGI-YGKIFAVSRKHAHAINNLR---------ENQNNQVKKDKKAAKTLGIVIGVFLLCW 230
Query: 279 LPYIIYFLLESSRVLDNPTLSF-LTTWLAISNSFCNCVIYSLSNSVFRLGLR 329
P LL+ P + F TW NS CN +IY FR L+
Sbjct: 231 FPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALK 282
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 33/292 (11%)
Query: 52 FLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHES 111
F+ I GNL +I LH T++ I +MA D +G + ++P + +
Sbjct: 55 FITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFT-IMPYSMIRSVENCWYFG 112
Query: 112 LT-CQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIW---- 166
LT C+++ +L S+ L +++DR+ AI PL Y+ +T ++ ++L W
Sbjct: 113 LTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPG 172
Query: 167 IYSCLIFLPSFFGWGKPGYHGDIFEWCATS--------WLTSAYFTGFIVCLLYAPAAFV 218
++ + + G GY DI C++S W T+ + GF + P + +
Sbjct: 173 AFAFGVVFSEAYADGIEGY--DILVACSSSCPVMFNKLWGTTLFMAGF-----FTPGSMM 225
Query: 219 VCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLW 278
V Y IF + R+H IN+ R ++ D++ A L + VF + W
Sbjct: 226 VGI-YGKIFAVSRKHAHAINNLR---------ENQNNQVKKDKKAAKTLGIVIGVFLLCW 275
Query: 279 LPYIIYFLLESSRVLDNPTLSF-LTTWLAISNSFCNCVIYSLSNSVFRLGLR 329
P LL+ P + F TW NS CN +IY FR L+
Sbjct: 276 FPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALK 327
>gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]
Length = 357
Score = 79.3 bits (194), Expect = 5e-15
Identities = 85/312 (27%), Positives = 135/312 (43%), Gaps = 38/312 (12%)
Query: 41 IFETVVIVLLTFLI---IAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVP 97
+F +++ LL FL+ A NL V+ H + + +MA +D+ V + LV
Sbjct: 38 VFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHN-LVASMAVSDVLV--AALVM 94
Query: 98 TLSLLHYSTGVHESL---TCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVT 154
LSL+H +G L CQ++ + + S+ + I++DRY +IT+ + Y
Sbjct: 95 PLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTR 154
Query: 155 PCRLRICIILIWIYSCLIFL-PSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYA 213
C + I L W S +I L P FGWG+ G E C S +Y V Y
Sbjct: 155 KCVSNVMIALTWALSAVISLAPLLFGWGETYSEGS--EECQVS-REPSYAVFSTVGAFYL 211
Query: 214 PAAFVVCFTYFHIFKIC--RQHTKEINDRRARFPSHEV-DSSRETGHSPDRRYAMVLFR- 269
P VV F Y+ I+K R +++ N + EV DS+++ R+A V F+
Sbjct: 212 PLC-VVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQP 270
Query: 270 -------------------ITSVFYMLWLPYIIYFLLESSRVLDNPTL-SFLTTWLAISN 309
+ VF + W+P+ + L+ D P + + WL SN
Sbjct: 271 EGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSN 330
Query: 310 SFCNCVIYSLSN 321
SF N +IY+ N
Sbjct: 331 SFFNPLIYTAFN 342
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 79.3 bits (194), Expect = 5e-15
Identities = 76/326 (23%), Positives = 128/326 (39%), Gaps = 39/326 (11%)
Query: 45 VVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHY 104
V + + +AGNL VI C L T+YFI +A ADL + + L + ++
Sbjct: 101 VFLAAFILMAVAGNLLVILSVACNRHLQT-VTNYFIVNLAVADLLLSATVLPFSATMEVL 159
Query: 105 STGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIL 164
C V+ + + + S+ L ISVDRY+ + L Y ++T + + L
Sbjct: 160 GFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILAL 219
Query: 165 IWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYF 224
+W+ + ++ + GW +P + F C + + Y VC Y P A +V Y
Sbjct: 220 LWVVALVVSVGPLLGWKEPVPPDERF--CGIT-EEAGYAVFSSVCSFYLPMAVIVVM-YC 275
Query: 225 HIFKICRQHTK--EINDRRARFPSHEVD------------------------------SS 252
++ + R T+ E +R R + EV S
Sbjct: 276 RVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSV 335
Query: 253 RETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLES--SRVLDNPTLSFLTTWLAISNS 310
R S +++ A L + VF + W P+ L S ++ + + + WL NS
Sbjct: 336 RLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNS 395
Query: 311 FCNCVIYSLSNSVFRLGLRRLSETMC 336
N +IY S+ F+ RL C
Sbjct: 396 CVNPLIYPCSSREFKRAFLRLLRCQC 421
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 79.0 bits (193), Expect = 6e-15
Identities = 87/324 (26%), Positives = 135/324 (41%), Gaps = 50/324 (15%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYS 105
++ L+T L IAGN V+ + C ++Y I ++A ADL V V+ ++P +S+
Sbjct: 87 ILTLITLLTIAGNCLVV-ISVCFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI 144
Query: 106 TG--VHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICII 163
G + C VF + + + S+ L IS+DRYL IT+PL+Y + I+
Sbjct: 145 GGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMIL 204
Query: 164 LIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTY 223
+W+ S I LP FGW + + D + + + Y T Y P + V+ F Y
Sbjct: 205 SVWLLSASITLPPLFGWAQ-NVNDDKVCLISQDFGYTIYST---AVAFYIPMS-VMLFMY 259
Query: 224 FHIFKICRQHTKEINDRRARFPSHEVDS--------------------SRETGH------ 257
+ I+K R+ + + FP E DS SR H
Sbjct: 260 YQIYKAARKSAAK--HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317
Query: 258 --SPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPT--------LSFLTTWLAI 307
+++ A L I F + WLP +FLL ++R T + WL
Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARPFICGTSCSCIPLWVERTFLWLGY 374
Query: 308 SNSFCNCVIYSLSNSVFRLGLRRL 331
+NS N IY+ N R R L
Sbjct: 375 ANSLINPFIYAFFNRDLRTTYRSL 398
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 79.0 bits (193), Expect = 6e-15
Identities = 87/324 (26%), Positives = 135/324 (41%), Gaps = 50/324 (15%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYS 105
++ L+T L IAGN V+ + C ++Y I ++A ADL V V+ ++P +S+
Sbjct: 87 ILTLITLLTIAGNCLVV-ISVCFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI 144
Query: 106 TG--VHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICII 163
G + C VF + + + S+ L IS+DRYL IT+PL+Y + I+
Sbjct: 145 GGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMIL 204
Query: 164 LIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTY 223
+W+ S I LP FGW + + D + + + Y T Y P + V+ F Y
Sbjct: 205 SVWLLSASITLPPLFGWAQ-NVNDDKVCLISQDFGYTIYST---AVAFYIPMS-VMLFMY 259
Query: 224 FHIFKICRQHTKEINDRRARFPSHEVDS--------------------SRETGH------ 257
+ I+K R+ + + FP E DS SR H
Sbjct: 260 YQIYKAARKSAAK--HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317
Query: 258 --SPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPT--------LSFLTTWLAI 307
+++ A L I F + WLP +FLL ++R T + WL
Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARPFICGTSCSCIPLWVERTFLWLGY 374
Query: 308 SNSFCNCVIYSLSNSVFRLGLRRL 331
+NS N IY+ N R R L
Sbjct: 375 ANSLINPFIYAFFNRDLRTTYRSL 398
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 79.0 bits (193), Expect = 6e-15
Identities = 87/324 (26%), Positives = 135/324 (41%), Gaps = 50/324 (15%)
Query: 46 VIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYS 105
++ L+T L IAGN V+ + C ++Y I ++A ADL V V+ ++P +S+
Sbjct: 87 ILTLITLLTIAGNCLVV-ISVCFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI 144
Query: 106 TG--VHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICII 163
G + C VF + + + S+ L IS+DRYL IT+PL+Y + I+
Sbjct: 145 GGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMIL 204
Query: 164 LIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTY 223
+W+ S I LP FGW + + D + + + Y T Y P + V+ F Y
Sbjct: 205 SVWLLSASITLPPLFGWAQ-NVNDDKVCLISQDFGYTIYST---AVAFYIPMS-VMLFMY 259
Query: 224 FHIFKICRQHTKEINDRRARFPSHEVDS--------------------SRETGH------ 257
+ I+K R+ + + FP E DS SR H
Sbjct: 260 YQIYKAARKSAAK--HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317
Query: 258 --SPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPT--------LSFLTTWLAI 307
+++ A L I F + WLP +FLL ++R T + WL
Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARPFICGTSCSCIPLWVERTFLWLGY 374
Query: 308 SNSFCNCVIYSLSNSVFRLGLRRL 331
+NS N IY+ N R R L
Sbjct: 375 ANSLINPFIYAFFNRDLRTTYRSL 398
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 79.0 bits (193), Expect = 6e-15
Identities = 74/305 (24%), Positives = 131/305 (42%), Gaps = 36/305 (11%)
Query: 55 IAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYAD--LFVGVSCLVPTLSLLHYSTGVHESL 112
+ GN VI+V + T Y + +A AD L + V LV + L H+ G +L
Sbjct: 73 LCGNSMVIYVILRYAKMKTATNIYILN-LAIADELLMLSVPFLVTSTLLRHWPFG---AL 128
Query: 113 TCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLI 172
C++ + +V S+ CL +SVDRY+A+ P+ + P ++ + +W+ S L+
Sbjct: 129 LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLV 188
Query: 173 FLPSFFGWGKPGYHGDIFEWC-------ATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFH 225
LP + + + D C A WL F++ L A +C+
Sbjct: 189 ILP-IVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLI- 246
Query: 226 IFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYF 285
I K+ K +R R +R+ +++ + VF + W+P+ +
Sbjct: 247 IAKMRMVALKAGWQQRKR---------------SERKITLMVMMVVMVFVICWMPFYVVQ 291
Query: 286 LLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQ 345
L+ D+ T+S L+ L +NS N ++Y + F+ +R+ +C S M D
Sbjct: 292 LVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRI---LCLSWM---DN 345
Query: 346 EAQEP 350
A+EP
Sbjct: 346 AAEEP 350
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 78.6 bits (192), Expect = 8e-15
Identities = 76/312 (24%), Positives = 136/312 (43%), Gaps = 32/312 (10%)
Query: 37 VDVCIFETVVIVLLTFLIIAGNLTVIF-VFHCAPLLHHYTTSYFIQTMAYADLFVGVSCL 95
V ++ +V+++LT L+ GNL VI + H L H T++ I +MA D +G CL
Sbjct: 22 VRASLYSLMVLIILTTLV--GNLIVIVSISHFKQL--HTPTNWLIHSMATVDFLLG--CL 75
Query: 96 VPTLSLLHYSTGVHESLTCQVFGYIIS--------VLKSVSMACLACISVDRYLAITKPL 147
V S+ V + C FG + +L S S+ L+ IS+DRY A+ PL
Sbjct: 76 VMPYSM------VRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPL 129
Query: 148 SYNQLVTPCRLRICIILIWIYSC-----LIFLPSFFGWGKPGYHGDIF--EWCATSWLTS 200
Y + + + I + W +IFL F + Y+ + C+ +
Sbjct: 130 RYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKI 189
Query: 201 AYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPD 260
+ F+ Y P + ++C Y+ I+ I ++ + I+D + ++ S +
Sbjct: 190 SGVLTFMTS-FYIPGSIMLC-VYYRIYLIAKEQARLISDANQKL-QIGLEMKNGISQSKE 246
Query: 261 RRYAMVLFRITSVFYMLWLPYIIYFLLES-SRVLDNPTLSFLTTWLAISNSFCNCVIYSL 319
R+ L + VF + W P+ I +++ + PTL+ + W NS N ++Y+
Sbjct: 247 RKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAF 306
Query: 320 SNSVFRLGLRRL 331
FR L+ +
Sbjct: 307 FYPWFRKALKMM 318
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.141 0.467
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,627,981
Number of Sequences: 37866
Number of extensions: 564162
Number of successful extensions: 2590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 285
Number of HSP's that attempted gapping in prelim test: 1674
Number of HSP's gapped (non-prelim): 904
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.